Simple, short peptide derivatives of a sulfonylindolecarboxamide (L-737,126) active in vitro against HIV-1 wild type and variants carrying non-nucleoside reverse transcriptase inhibitor resistance mutations

Journal of Medicinal Chemistry

Volumn 47, Issue 15, 2004, Pages 3892-3896

  Silvestri, Romano ^a   Artico, Marino ^a   De Martino, Gabriella ^a   La Regina, Giuseppe ^a   Loddo, Roberta ^b   La Colla, Massimiliano ^b   La Colla, Paolo ^b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3 [(3,5 DIMETHYLPHENYL)SULFONYL] 1H NDOLE 2 CARBOXYLIC ACID; ALANINAMIDE; ALANINE DERIVATIVE; AMIDE; ANTIRETROVIRUS AGENT; BENZENESULFONIC ACID DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; EFAVIRENZ; GLYCINAMIDE; HYDRAZIDE DERIVATIVE; INDOLE DERIVATIVE; L 737126; METHYL GROUP; N [3 [(3,5 DIMETHYLPHENYL)SULFONYL] 5 CHLORO 1H INDOLE 2 CARBONYL]GLYCINAMIDE; N [3 [(3,5 DIMETHYLPHENYL)SULFONYL] 5 CHLORO 1H INDOLE 2 CARBONYL]GLYCINE ETHYL ESTER; N [3 [(3,5 DIMETHYLPHENYL)SULFONYL] 5 CHLORO 1H INDOLE 2 CARBONYL]GLYCINE HYDRAZIDE; NEVIRAPINE; PEPTIDE DERIVATIVE; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; SULFONYLINDOLECARBOXAMIDE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; NONHUMAN; STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE; VIRUS MUTANT;

ANTI-HIV AGENTS; CELL LINE; DRUG RESISTANCE, VIRAL; HIV-1; HUMANS; INDOLES; MUTATION; REVERSE TRANSCRIPTASE INHIBITORS; SULFONES;

EID: 3142651936     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm031147e     Document Type: Article

References (13)

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