Letter to the Editor: A regulatory view on the discussion on the role of alternative methods in the risk assessment of chemicals in the context of REACH

Archives of Toxicology

Volumn 83, Issue 1, 2009, Pages 9-10

  Gundert Remy, Ursula ^a   Bernauer, Ulrike ^a   Madle, Stephan ^a   Oberemm, Axel ^a   Schulte, Agnes ^a   Richter Reichhelm, Hans Bernhard ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

LAW; MEDICAL RESEARCH; NOTE; PRIORITY JOURNAL; RISK ASSESSMENT; TOXICOKINETICS;

ANIMAL TESTING ALTERNATIVES; ANIMALS; ANIMALS, LABORATORY; DATABASES, FACTUAL; ENVIRONMENTAL EXPOSURE; EUROPE; HUMANS; RISK ASSESSMENT; TOXICITY TESTS;

EID: 58149481489     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-008-0383-x     Document Type: Note

References (12)

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3. U Bernauer R Ellrich B Heinrich-Hirsch W Teubner B Vieth U Gundert-Remy 2002 Expression of cytochrome P450 enzymes in human colon IARC Sci Publ 156 487 499
4. U Bernauer H Garritsen B Heinrich-Hirsch U Gundert-Remy 2003 Immunochemical analysis of cytochrome P450 variability in human leukapheresed samples and its consequences for the risk assessment process Regul Toxicol Pharmacol 37 318 327
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6. Bernauer U, Gundert-Remy U (2008) (in press)
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9. ET Hulzebos JD Walker I Gerner K Schlegel 2005 Use of structural alerts to develop rules for identifying chemical substances with skin irritating or skin corrosion potential QSAR Comb Sci 24 232 242
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11. H Mielke A Gundert K Abraham U Gundert-Remy 2005 Acute inhalative exposure assessment: derivation of guideline levels with special regard to sensitive subpopulations and time scaling Toxicology 214 256 267
12. Settels E, Bernauer U, Palavinskas R, Klaffke HS, Gundert-Remy U, Appel KE (2008) Human CYP2E1 mediates the formation of glycidamide from acrylamide. Arch Toxicol. doi: 10.1007/s00204-008-0296-8