Use of structural alerts to develop rules for identifying chemical substances with skin irritation or skin corrosion potential

QSAR and Combinatorial Science

Volumn 24, Issue 3, 2005, Pages 332-342

  Hulzebos, Etje ^a   Walker, John D ^b   Gerner, Ingrid ^c   Schlegel, Kerstin ^c  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

Author keywords

Skin corrosion; Skin irritation; Structural alerts

Indexed keywords

STRUCTURAL PROPERTIES;

CHEMICAL SUBSTANCE; CORROSION POTENTIALS; LIMIT VALUES; MECHANISM-BASED; PHYSICOCHEMICAL PROPERTY; SKIN CORROSION; SKIN IRRITATION; SKIN LESION; STRUCTURAL ALERT; USER FRIENDLY;

CORROSION;

ACID ANHYDRIDE; ACID HALIDE; ACRYLIC ACID DERIVATIVE; ALDEHYDE; ALIPHATIC AMINE; ALIPHATIC CARBOXYLIC ACID; ALKANOL; ALLYL COMPOUND; AMINE; AROMATIC AMINE; AZIRIDINE DERIVATIVE; BENZANTHRONE DERIVATIVE; BENZOIC ACID DERIVATIVE; BENZYL DERIVATIVE; DISULFIDE; EPOXIDE; ETHYLENE GLYCOL DERIVATIVE; HALOGENATED HYDROCARBON; HETEROCYCLIC AMINE; HYDRAZINE DERIVATIVE; HYDRAZONE DERIVATIVE; HYDROPEROXIDE; ISOTHIOCYANIC ACID DERIVATIVE; LACTONE DERIVATIVE; METHACRYLIC ACID DERIVATIVE; OCTANOL; PHENOL DERIVATIVE; QUATERNARY AMMONIUM DERIVATIVE; QUINONE DERIVATIVE; SILANE DERIVATIVE; SILICON DERIVATIVE; SULFATE; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; WATER;

ARTICLE; CORROSION; DATA BASE; DRUG CLASSIFICATION; DRUG MECHANISM; DRUG STRUCTURE; EUROPEAN UNION; EXPERT SYSTEM; HUMAN; MOLECULAR WEIGHT; PARTITION COEFFICIENT; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SKIN CORROSION; SKIN IRRITATION; STRATUM CORNEUM;

ANIMALIA;

EID: 18344395176     PISSN: 1611020X     EISSN: None     Source Type: Journal    
DOI: 10.1002/qsar.200430905     Document Type: Article

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