Toxicological comments to the discussion about REACH (H. Greim, M. Arand, H. Autrup, H.M. Bolt, J. Bridges, E. Dybing, R. Glomot, V. Foa, R. Schulte-Hermann, Arch Toxicol 2006, 80: 121-124). Reply to the letter to the editor: The need for a new toxicity testing and risk analysis paradigm to implement REACH or any other large scale testing initiative, by B.J. Blaauboer and M.E. Andersen...

Archives of Toxicology

Volumn 81, Issue 12, 2007, Pages 895-896

  Greim, Helmut ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HAZARD ASSESSMENT; HEALTH; HUMAN; MEDICAL LITERATURE; NOTE; PRIORITY JOURNAL; RISK ASSESSMENT; SCIENTIFIC LITERATURE; TOXICITY TESTING; TOXICOKINETICS; TOXICOLOGY;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL EXPOSURE; EUROPEAN UNION; HAZARDOUS SUBSTANCES; HUMANS; NO-OBSERVED-ADVERSE-EFFECT LEVEL; RISK ASSESSMENT; TOXICITY TESTS;

EID: 36749097264     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-007-0216-3     Document Type: Note

References (10)

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2. Andersen ME (2003) Toxicokinetic modeling and its applications in chemical risk assessment. Toxicol Lett 138:9-27
3. Blaauboer BJ (2003) The integration of data on physico-chemical properties, in vitro-derived toxicity data and physiologically based kinetic and dynamic modelling as a tool in hazard and risk assessment. A Comment Toxicol Lett 138:161-171
4. Blaauboer BJ, Andersen ME (2007) The need for a new toxicity testing and risk analysis paradigm to implement REACH or any other large scale testing initiative. Arch Toxicol 81:385-387
5. Csanády GA, Filser JG (2007) A physiological toxicokinetic model for inhaled propylene oxide in rat and human with special emphasis on the nose. Toxicol Sci 95:37-62
6. Csanády GA, Denk B, Pütz C, Kreuzer PE, Kessler W, Baur C, Gargas ML, Filser JG (2000) A physiological toxicokinetic model for exogenous and endogenous ethylene and ethylene oxide in rat, mouse, and human: formation of 2-hydroxyethyl adducts with hemoglobin and DNA. Toxicol Appl Pharmacol 165:1-26
7. Csanády GA, Kessler W, Hoffmann HD, Filser JG (2003) A toxicokinetic model for styrene and its metabolite styrene-7,8-oxide in mouse, rat and human with special emphasis on the lung. Toxicol Lett 138:75-102
8. Eisenbrand G, Pool-Zobel B, Baker V, Balls M, Blaauboer BJ, Boobis A, Carere A, Kevekordes S, Lhuguenot J-C, Pieters R, Kleiner J (2002) Methods of in vitro toxicology. Food Chem Toxicol 40:193-236
9. DeJongh J, Nordin-Andersson M, Ploeger B, Forsby A (1999) Estimation of systemic toxicity of acrylamide by integration of in vitro toxicity data with kinetic simulations. Toxicol Appl Pharmacol 158:261-268
10. Greim H, Arand M, Autrup H, Bolt HM, Bridges J, Dybing E, Glomot R, Foa V, Schulte-Hermann R (2006) Toxicological comments to the discussion about REACH. Arch Toxicol 80:121-124