Signaling and invasin-promoted uptake via integrin receptors

Microbes and Infection

Volumn 2, Issue 7, 2000, Pages 793-801

  Isberg, Ralph R ^a   Hamburger, Zsuzsa ^b   Dersch, Petra ^a,c  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Integrin; Invasin; Receptor; Signalling; Yersinia

Indexed keywords

FOCAL ADHESION KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; INTEGRIN RECEPTOR; INVASIN;

ARTICLE; BINDING AFFINITY; CAPPING PHENOMENON; CELL INVASION; CYTOSKELETON; ENDOCYTOSIS; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION; YERSINIA; YERSINIOSIS;

EID: 0033920740     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1286-4579(00)90364-2     Document Type: Review

References (50)

1. Finlay B.B., Falkow S. Common themes in microbial pathogenicity revisited. Microbiol. Mol. Biol. Rev. 28:1997;136-169.
2. Sansonetti P.J., Tran Van Nhieu G., Egile C. Rupture of the intestinal epithelial barrier and mucosal invasion by Shigella flexneri. Clin. Infect. Dis. 30:1999;466-475.
3. Cirillo D.M., Valdivia R.H., Monack D.M., Falkow S. Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival. Mol. Microbiol. 65:1998;175-188.
4. Marra A., Isberg R.R. Invasin-dependent and invasin-independent pathways for translocation of Yersinia pseudotuberculosis across the Peyer's patch intestinal epithelium. Infect. Immun. 90:1997;3412-3421.
5. Pepe J.C., Miller V.L. Yersinia enterocolitica invasin: a primary role in the initiation of infection. Proc. Natl. Acad. Sci. USA. 63:1993;6473-6477.
6. Pepe J.C., Wachtel M.R., Wagar E., Miller V.L. Pathogenesis of defined invasion mutants of Yersinia enterocolitica in a BALB/c mouse model of infection. Infect. Immun. 10:1995;4837-4848.
7. Bottone E.J. Yersinia enterocolitica: the charisma continues. Clin. Microbiol. Rev. 18:1997;257-276.
8. Santoro M.J., Chen Y.K., Seid N.S., Abdulian J.D., Collen M.J. Yersinia enterocolitica liver abscesses unmasking idiopathic hemochromatosis. J. Clin. Gastroenterol. 60:1994;253-254.
9. Isberg R.R., Leong J.M. Multiple β1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cells. Cell. 69:1990;861-871.
10. Hynes R.O. Integrins: Versatility, Modulation, Signaling in Cell Adhesion. Cell. 66:1992;11-25.
11. Clark M.A., Hirst B.H., Jepson M.A. M-cell surface b1 integrin expression and invasin-mediated targeting of Yersinia pseudotuberculosis to mouse Peyer's patch M cells. Infect. Immun. 62:1998;1237-1243.
12. Cornelis G.R., Boland A., Boyd A.P., Geuijen C., Iriarte M., Neyt C., Sory M.P., Stainier I. The virulence plasmid of Yersinia, an antihost genome. Microbiol. Mol. Biol. Rev. 16:1998;1315-1352.
13. Persson C., Carballeira N., Wolf-Watz H., Fallman M. The PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation of p130Cas and FAK, the associated accumulation of these proteins in peripheral focal adhesions. EMBO J. 16:1997;2307-2318.
14. Black D.S., Bliska J.B. Identification of p130Cas as a substrate of Yersinia YopH (Yop51), a bacterial protein tyrosine phosphatase that translocates into mammalian cells and targets focal adhesions. EMBO J. 13:1997;2730-2744.
15. Rosqvist R., Persson C., Hakansson S., Nordfeldt R., Wolf-Watz H. Translocation of the Yersinia YopE and YopH virulence proteins into target cells is mediated by YopB and YopD. Contrib. Microbiol. Immunol. 65:1995;230-234.
16. Agin T.S., Wolf M.K. Identification of a family of intimins common to Escherichia coli causing attaching-effacing lesions in rabbits, humans, swine. Infect. Immun. 65:1997;320-326.
17. Kenny B., Finlay B.B. Intimin-dependent binding of enteropathogenic Escherichia coli to host cells triggers novel signaling events, including tyrosine phosphorylation of phospholipase C-gamma1. Infect. Immun. 9:1997;2528-2536.
18. Leong J.M., Fournier R.S., Isberg R.R. Identification of the integrin binding domain of the Yersinia pseudotuberculosis invasin protein. EMBO J. 14:1990;1979-1989.
19. Leong J.M., Morrissey P.E., Marra A., Isberg R.R. An aspartate residue of the Yersinia pseudotuberculosis invasin protein that is critical for integrin binding. EMBO J. 84:1995;422-431.
20. Leahy D.J., Aukhil I., Erickson H.P. A crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region. Cell. 271:1996;155-164.
21. Saltman L.H., Lu Y., Zaharias E.M., Isberg R.R. A region of the Yersinia pseudotuberculosis invasin protein that contributes to high affinity binding to integrin receptors. J. Biol. Chem. 269:1996;23438-23444.
22. Aota S., Nomizu M., Yamada K.M. The short amino acid sequence Pro-His-Ser-Arg-Asn in human fibronectin enhances cell-adhesive function. J. Biol. Chem. 286:1994;24756-24761.
23. Hamburger Z.A., Brown M.S., Isberg R.R., Bjorkman P.J. Crystal Structure of Invasin: A Bacterial Integrin-Binding Protein. Science. 18:1999;291-295.
24. Dersch P., Isberg R.R. A region of the Yersinia pseudotuberculosis invasin protein enhances integrin-mediated uptake into mammalian cells and promotes self-association. EMBO J. 163:1999;1199-1213.
25. Weis W.I., Taylor M.E., Drickamer K. The C-type lectin superfamily in the immune system. Immunol. Rev. 266:1998;19-34.
26. Tran Van, Nhieu G., Isberg R.R. The Yersinia pseudotuberculosis invasin protein and human fibronectin bind to mutually exclusive sites on the a5b1 integrin receptor. J. Biol. Chem. 60:1991;24367-24375.
27. Rankin S., Isberg R.R., Leong J.M. The integrin-binding domain of invasin is sufficient to allow bacterial entry into mammalian cells. Infect. Immun. 12:1992;3909-3912.
28. Tran, Van Nhieu G., Isberg R.R. Bacterial internalization mediated by β1 chain integrins is determined by ligand affinity and receptor density. EMBO J. 199:1993;1887-1895.
29. Destrooper B., Van Leuven F., Carmeliet G., Van Den Berghe H., Cassiman J.J. Cultured human fibroblasts contain a large pool of precursor β1-integrin but lack an intracellular pool of mature subunit. Eur. J. Biochem. 1991;25-33.
30. Reszka A.A., Hayashi Y., Horwitz A.F. Identification of amino acid sequences in the integrin β1 cytoplasmic domain implicated in cytoskeletal association. J. Cell Biol. 268:1992.
31. Otey C.A., Vasquez G.B., Burridge K., Erickson B.W. Mapping of the alpha-actinin binding site within the β1 integrin cytoplasmic domain. J. Biol. Chem. 130:1993;21193-21197.
32. Schaller M.D., Otey C.A., Hildebrand J.D., Parsons J.T. Focal adhesion kinase and paxillin bind to peptides mimicking β integrin cytoplasmic domains. J. Cell Biol. 274:1995;1181-1187.
33. Zhang X.A., Hemler M.E. Interaction of the integrin β1 cytoplasmic domain with ICAP-1 protein. J. Biol. Chem. 271:1999;11-19.
34. Tran Van, Nhieu G., Krukonis E.S., Reszka A.A., Horwitz A.F., Isberg R.R. Mutations in the cytoplasmic domain of the integrin β1 chain indicate a role for endocytosis factors in bacterial internalization. J. Biol. Chem. 15:1996;7665-7672.
35. Rosenshine I., Finlay B.B. Exploitation of host signal transduction pathways and cytoskeletal functions by invasive bacteria. Bioessays. 88:1993;17-24.
36. Bliska J.B., Guan K.L., Dixon J.E., Falkow S. Tyrosine phosphate hydrolysis of host proteins by an essential Yersinia virulence determinant. Proc. Natl. Acad. Sci. USA. 27:1991;1187-1191.
37. Fu Y., Galan J.E. The Salmonella typhimurium tyrosine phosphatase SptP is translocated into host cells and disrupts the actin cytoskeleton. Mol. Microbiol. 401:1998;359-368.
38. Fu Y., Galan J.E. A Salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion. Nature. 13:1999;293-297.
39. Rosqvist R., Magnusson K.E., Wolf W.H. Target cell contact triggers expression and polarized transfer of Yersinia YopE cytotoxin into mammalian cells. EMBO J. 17:1994;964-972.
40. Schlaepfer D.D., Broome M.A., Hunter T. Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, Nck adaptor proteins. Mol. Cell. Biol. 14:1997;1702-1713.
41. Schaller M.D., Hildebrand J.D., Shannon J.D., Fox J.W., Vines R.R., Parsons J.T. Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src. Mol. Cell Biol. 110:1994;1680-1688.
42. Ilic D., Damsky C.H., Yamamoto T. Focal adhesion kinase: at the crossroads of signal transduction. J. Cell. Sci. 377:1997;401-407.
43. Ilic D., Furuta Y., Kanazawa S., Takeda N., Sobue K., Nakatsuji N., Nomura S., Fujimoto J., Okada M., Yamamoto T. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature. 95:1995;539-544.
44. Alrutz M.A., Isberg R.R. Involvement of focal adhesion kinase in invasin-mediated uptake. Proc. Natl. Acad. Sci. USA. 375:1998;13658-13663.
45. Just I., Selzer J., Wilm M., Von Eichel-Streiber C., Mann M., Aktories K. Glucosylation of Rho proteins by Clostridium difficile toxin B. Nature. 9:1995;500-503.
46. Tapon N., Hall A. Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton. Curr. Opin. Cell Biol. 9:1997;86-92.
47. Welch M.D. The world according to Arp: regulation of actin nucleation by the Arp2/3 complex. Trends Cell Biol. 17:1999;423-427.
48. Miki H., Suetsugu S., Takenawa T. WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac. EMBO J. 95:1998;6932-6941.
49. Locher K.P., Rees B., Koebnik R., Mitschler A., Mouliner L., Rosenbusch J.P., Moras D. Transmembrane signaling across the ligand-gated FhuA receptor: Crystal structures of free and ferrichrome-bound states reveal allosteric changes. Cell. 82:1998;771-778.
50. Ferguson A.D., Hofmann E., Coulton J.W., Diederichs K., Welte W. Siderophore-mediated iron transport: crystal structure of FhuA with bound lipopolysaccharide. Science. 1998;2215-2220.