Hypoxia and leucine deprivation induce human insulin-like growth factor binding protein-1 hyperphosphorylation and increase its biological activity

Endocrinology

Volumn 150, Issue 1, 2009, Pages 220-231

  Seferovic, Maxim D ^a   Ali, Rashad ^a   Kamei, Hiroyasu ^b   Liu, Suya ^a   Khosravi, Javad M ^c   Nazarian, Steven ^a   Han, Victor K M ^a   Duan, Cunming ^b,d   Gupta, Madhulika B ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b UNIVERSITY OF MICHIGAN   (United States)

^c Diagnostic Systems Laboratories Inc   (United States)

^d OCEAN UNIVERSITY OF CHINA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

LEUCINE; SERINE; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN BINDING PROTEIN 1;

ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; DISSOCIATION CONSTANT; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOBLOTTING; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MALNUTRITION; PROTEIN PHOSPHORYLATION; TANDEM MASS SPECTROMETRY;

CARCINOMA, HEPATOCELLULAR; CELL HYPOXIA; CELL LINE, TUMOR; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENETIC VARIATION; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; KINETICS; LEUCINE; LIVER NEOPLASMS; MASS SPECTROMETRY; PHOSPHOPEPTIDES; PHOSPHORYLATION;

EID: 58149460381     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-0657     Document Type: Article

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