Are insulin-like growth factor and its binding proteins 1 and 3 clinically useful as markers of malnutrition, sarcopenia and inflammation in end-stage renal disease?

European Journal of Clinical Nutrition

Volumn 60, Issue 6, 2006, Pages 718-726

  Axelsson, Jonas ^a   Qureshi, A R ^a   Divino Filho, J C ^a   Barany P ^a   Heimburger O ^a   Lindholm, B ^a   Stenvinkel, P ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Chronic renal failure; End stage renal disease; IGF; Inflammation; Malnutrition

Indexed keywords

ALBUMIN; ANGIOTENSIN RECEPTOR ANTAGONIST; ASCORBIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; C REACTIVE PROTEIN; CALCIUM CHANNEL BLOCKING AGENT; CREATININE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INSULIN; INTERLEUKIN 6; IRON; NITROGEN; ORAL ANTIDIABETIC AGENT; PHOSPHATE BINDING AGENT; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; VITAMIN B GROUP; VITAMIN D;

ADULT; ARTICLE; BODY COMPOSITION; BODY MASS; CARDIOVASCULAR DISEASE; CHRONIC INFLAMMATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DIABETES MELLITUS; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DIET RESTRICTION; DISEASE ASSOCIATION; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; GRIP STRENGTH; HAND GRIP; HUMAN; INSULIN RESISTANCE; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MUSCLE ATROPHY; NUTRITIONAL STATUS; PROTEIN CALORIE MALNUTRITION; PROTEIN INTAKE; SENSITIVITY AND SPECIFICITY;

AGE FACTORS; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CROSS-SECTIONAL STUDIES; FEMALE; GLOMERULAR FILTRATION RATE; HAND STRENGTH; HUMANS; INFLAMMATION; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INTERLEUKIN-6; KIDNEY FAILURE, CHRONIC; MALE; MALNUTRITION; MIDDLE AGED; MULTIVARIATE ANALYSIS; MUSCULAR ATROPHY; NUTRITION ASSESSMENT; NUTRITION DISORDERS; NUTRITIONAL STATUS; PREDICTIVE VALUE OF TESTS; SOMATOMEDINS;

EID: 33744919259     PISSN: 09543007     EISSN: 14765640     Source Type: Journal    
DOI: 10.1038/sj.ejcn.1602373     Document Type: Article

References (48)

1. Axelsson J, Rashid Qureshi A, Suliman ME, Honda H, Pecoits-Filho R, Heimburger O et al. (2004). Truncal fat mass as a contributor to inflammation in end-stage renal disease. Am J Clin Nutr 80, 1222-1229.
2. Barbieri M, Ferrucci L, Ragno E, Corsi A, Bandinelli S, Bonafe M et al. (2003). Chronic inflammation and the effect of IGF-I on muscle strength and power in older persons. Am J Physiol Endocrinol Metab 284, E481-E487.
3. Bergstrom J (1995). Nutrition and mortality in hemodialysis. J Am Soc Nephrol 6, 1329-1341.
4. Boonen S, Lysens R, Verbeke G, Joosten E, Dejaeger E, Pelemans W et al. (1998). Relationship between age-associated endocrine deficiencies and muscle function in elderly women: A crosssectional study. Age Ageing 27, 449-454.
5. Borst SE, Lowenthal DT (1997). Role of IGF-I in muscular atrophy of aging. Endocrine 7, 61-63.
6. Brismar K, Fernqvist-Forbes E, Wahren J, Hall K (1994). Effect of insulin on the hepatic production of insulin-like growth factor-binding protein-1 (IGFBP-1), IGFBP-3, and IGF-I in insulin-dependent diabetes. J Clin Endocrinol Metab 79, 872-878.
7. Cappola AR, Bandeen-Roche K, Wand GS, Volpato S, Fried LP (2001). Association of IGF-I levels with muscle strength and mobility in older women. J Clin Endocrinol Metab 86, 4139-4146.
8. Clemmons DR, Busby WH, Arai T, Nam TJ, Clarke JB, Jones JI et al. (1995). Role of insulin-like growth factor binding proteins in the control of IGF actions. Prog Growth Factor Res 6, 357-366.
9. de Martino M, Galli L, Chiarelli F, Verrotti A, Rossi ME, Bindi G et al. (2000). Interleukin-6 release by cultured peripheral blood mononuclear cells inversely correlates with height velocity, bone age, insulin-like growth factor-I, and insulin-like growth factor binding protein-3 serum levels in children with perinatal HIV-1 infection. Clin Immunol 94, 212-218.
10. De Meyts P, Whittaker J (2002). Structural biology of insulin and IGF1 receptors: Implications for drug design. Nat Rev Drug Discov 1, 769-783.
11. Detsky AS, McLaughlin JR, Baker JP, Johnston N, Whittaker S, Mendelson RA et al. (1987). What is subjective global assessment of nutritional status? JPEN J Parenter Enteral Nutr 11, 8-13.
12. Ding H, Qing DP, Kopple JD (1997). IGF-1 resistance in chronic renal failure: Current evidence and possible mechanisms. Kidney Int Suppl 62, S45-S47.
13. Divino Filho JC, Hazel SJ, Furst P, Bergstrom J, Hall K (1998). Glutamate concentration in plasma, erythrocyte and muscle in relation to plasma levels of insulin-like growth factor (IGF)-I, IGF binding protein-1 and insulin in patients on haemodialysis. J Endocrinol 156, 519-527.
14. Frystyk J, Ivarsen P, Skjaerbaek C, Flyvbjerg A, Pedersen EB, Orskov H (1999). Serum-free insulin-like growth factor I correlates with clearance in patients with chronic renal failure. Kidney Int 56, 2076-2084.
15. Gibson TL, Cohen P (1999). Inflammation-related neutrophil proteases, cathepsin G and elastase, function as insulin-like growth factor binding protein proteases. Growth Horm IGF Res 9, 241-253.
16. Gourmelen M, Le Bouc Y, Girard F, Binoux M (1984). Serum levels of insulin-like growth factor (IGF) and IGF binding protein in constitutionally tall children and adolescents. J Clin Endocrinol Metab 59, 1197-1203.
17. Hardouin S, Gourmelen M, Noguiez P, Seurin D, Roghani M, Le Bouc Y et al. (1989). Molecular forms of serum insulin-like growth factor (IGF)-binding proteins in man: Relationships with growth hormone and IGFs and physiological significance. J Clin Endocrinol Metab 69, 1291-1301.
18. Hintz RL (1984). Plasma forms of somatomedin and the binding protein phenomenon. Clin Endocrinol Metab 13, 31-42.
19. Hokken-Koelega AC, Hackeng WH, Stijnen T, Wit JM, de Muinck Keizer-Schrama SM, Drop SL (1990). Twenty-four-hour plasma growth hormone (GH) profiles, urinary GH excretion, and plasma insulin-like growth factor-I and -II levels in prepubertal children with chronic renal insufficiency and severe growth retardation. J Clin Endocrinol Metab 71, 688-695.
20. Iglesias P, Diez JJ, Fernandez-Reyes MJ, Mendez J, Bajo MA, Aguilera A et al. (2004). Growth hormone, IGF-I and its binding proteins (IGFBP-1 and -3) in adult uraemic patients undergoing peritoneal dialysis and haemodialysis. Clin Endocrinol (Oxford) 60, 741-749.
21. Jacob V, Le Carpentier JE, Salzano S, Naylor V, Wild G, Brown CB et al. (1990). IGF-I, a marker of undernutrition in hemodialysis patients. Am J Clin Nutr 52, 39-44.
22. Janssen JA, Stolk RP, Pols HA, Grobbee DE, Lamberts SW (1998). Serum free and total insulin-like growth factor-I, insulin-like growth factor binding protein-1 and insulin-like growth factor binding protein-3 Levels in healthy elderly individuals. Relation to self-reported quality of health and disability. Gerontology 44, 277-280.
23. Justova V, Lacinova Z, Melenovsky V, Marek J, Holly JM, Hass T (2001). The changes of IGF binding proteins after rhGH administration to patients totally dependent on parenteral nutrition. Growth Horm IGF Res 11, 407-415.
24. Kaufman CR, Catanese VM (1995). Pre- and post-translational regulation of renal insulin-like growth factor binding protein-1 in insulin-deficient diabetes. J Investig Med 43, 178-186.
25. Kerr PG, Strauss BJG, Atkins RC (1996). Assessment of the nutritional state of dialysis patients. Blood Purif 14, 382-387.
26. Kostka T, Arsac LM, Patricot MC, Berthouze SE, Lacour JR, Bonnefoy M (2000). Leg extensor power and dehydroepiandrosterone sulfate, insulin-like growth factor-I and testosterone in healthy active elderly people. Eur J Appl Physiol 82, 83-90.
27. Krabbe KS, Pedersen M, Bruunsgaard H (2004). Inflammatory mediators in the elderly. Exp Gerontol 39, 687-699.
28. Lazarus DD, Moldawer LL, Lowry SF (1993). Insulin-like growth factor-1 activity is inhibited by interleukin-1 alpha, tumor necrosis factor-alpha, and interleukin-6. Lymphokine Cytokine Res 12, 219-223.
29. Lee PD, Rosenfeld RG (1987). Clinical utility of insulin-like growth factor assays. Pediatrician 14, 154-161.
30. Martinez V, Balbin M, Ordonez FA, Rodriguez J, Garcia E, Medina A et al. (1999). Hepatic expression of growth hormone receptor/binding protein and insulin-like growth factor I genes in uremic rats. Influence of nutritional deficit. Growth Horm IGF Res 9, 61-68.
31. Mortensen DL,Won WB, Siu J, Reifsnyder D, Gironella M, Etcheverry T et al. (1997). Insulin-like growth factor binding protein-1 induces insulin release in the rat. Endocrinology 138, 2073-2080.
32. Moses AC, Young SC, Morrow LA, O'Brien M, Clemmons DR (1996). Recombinant human insulin-like growth factor I increases insulin sensitivity and improves glycemic control in type II diabetes. Diabetes 45, 91-100.
33. Muntner P, He J, Chen J, Fonseca V, Whelton PK (2004). Prevalence of non-traditional cardiovascular disease risk factors among persons with impaired fasting glucose, impaired glucose tolerance, diabetes, and the metabolic syndrome: Analysis of the Third National Health and Nutrition Examination Survey (NHANES III). Ann Epidemiol 14, 686-695.
34. Musaro A, McCullagh K, Paul A, Houghton L, Dobrowolny G, Molinaro M et al. (2001). Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle. Nat Genet 27, 195-200.
35. Owino V, Yang SY, Goldspink G (2001). Age-related loss of skeletal muscle function and the inability to express the autocrine form of insulin-like growth factor-1 (MGF) in response to mechanical overload. FEBS Lett 505, 259-263.
36. Papadakis MA, Grady D, Tierney MJ, Black D, Wells L, Grunfeld C (1995). Insulin-like growth factor 1 and functional status in healthy older men. J Am Geriatr Soc 43, 1350-1355.
37. Powell DR, Durham SK, Brewer ED, Frane JW, Watkins SL, Hogg RJ et al. (1999). Effects of chronic renal failure and growth hormone on serum levels of insulin-like growth factor-binding protein-4 (IGFBP-4) and IGFBP-5 in children: A report of the Southwest Pediatric Nephrology Study Group. J Clin Endocrinol Metab 84, 596-601.
38. Powell DR, Durham SK, Liu F, Baker BK, Lee PD, Watkins SL et al. (1998). The insulin-like growth factor axis and growth in children with chronic renal failure: A report of the Southwest Pediatric Nephrology Study Group. J Clin Endocrinol Metab 83, 1654-1661.
39. Powell DR, Liu F, Baker BK, Lee PD, Hintz RL (1996). Insulin-like growth factor binding proteins as growth inhibitors in children with chronic renal failure. Pediatr Nephrol 10, 343-347.
40. Qureshi AR, Alvestrand A, Danielsson A, Divino-Filho JC, Gutierrez A, Lindholm B et al. (1998). Factors predicting malnutrition in hemodialysis patients: A cross-sectional study. Kidney Int 53, 773-782.
41. Rabkin R, Fervenza FC, Maidment H, Ike J, Hintz R, Liu F et al. (1996). Pharmacokinetics of insulin-like growth factor-1 in advanced chronic renal failure. Kidney Int 49, 1134-1140.
42. Ranke MB, Schweizer R, Elmlinger MW,Weber K, Binder G, Schwarze CP et al. (2001). Relevance of IGF-I, IGFBP-3, and IGFBP-2 measurements during GH treatment of GH-deficient and non-GH-deficient children and adolescents. Horm Res 55, 115-124.
43. Shen WH, Zhou JH, Broussard SR, Freund GG, Dantzer R, Kelley KW (2002). Proinflammatory cytokines block growth of breast cancer cells by impairing signals from a growth factor receptor. Cancer Res 62, 4746-4756.
44. Statistics NCfH (1996). The Third National Health and Nutrition Examination Survey, NHANES III (1988-94).Westat Inc.: Hyattsville, MD, USA.
45. Stenvinkel P, Heimburger O, Paultre F, Diczfalusy U, Wang T, Berglund L et al. (1999). Strong association between malnutrition, inflammation, and atherosclerosis in chronic renal failure. Kidney Int 55, 1899-1911.
46. Tonshoff B, Blum WF, Wingen AM, Mehls O (1995). Serum insulinlike growth factors (IGFs) and IGF binding proteins 1, 2, and 3 in children with chronic renal failure: Relationship to height and glomerular filtration rate. The European Study Group for Nutritional Treatment of Chronic Renal Failure in Childhood. J Clin Endocrinol Metab 80, 2684-2691.
47. Veldhuis JD, Johnson ML, Wilkowski MJ, Iranmanesh A, Bolton WK (1991). Neuroendocrine alterations in the somatotrophic axis in chronic renal failure. Acta Paediatr Scand Suppl 379, 12-22. discussion 23.
48. Wolk K, Larsson SC, Vessby B, Wolk A, Brismar K (2004). Metabolic, anthropometric, and nutritional factors as predictors of circulating insulin-like growth factor binding protein-1 levels in middle-aged and elderly men. J Clin Endocrinol Metab 89, 1879-1884.