MEKK3 initiates transforming growth factor β2-dependent epithelial-to-mesenchymal transition during endocardial cushion morphogenesis

Circulation Research

Volumn 103, Issue 12, 2008, Pages 1430-1440

  Stevens, Mark V ^a   Broka, Derrick M ^a   Parker, Patti ^a   Rogowitz, Elisa ^a   Vaillancourt, Richard R ^a   Camenisch, Todd D ^a,b,c  

^a UNIVERSITY OF ARIZONA   (United States)

^b University of Arizona   (United States)

^c UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

Endocardial cushions; Epithelial to mesenchymal transition; Heart; MEKK3; TGF 2

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 3; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA2; MAP3K3 PROTEIN, MOUSE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EMBRYO; ENDOCARDIAL CUSHION; ENDOCARDIUM; ENZYME ACTIVITY; EPITHELIUM CELL; FEMALE; GENE EXPRESSION; HEART DEVELOPMENT; HEART MUSCLE CELL; HEART VENTRICLE SEPTUM; IN VITRO STUDY; IN VIVO STUDY; MESENCHYME CELL; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; CELL DIFFERENTIATION; COMPARATIVE STUDY; CYTOLOGY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; MESODERM; METABOLISM; PHYSIOLOGY; PRENATAL DEVELOPMENT;

ANIMALS; CELL DIFFERENTIATION; ENDOCARDIAL CUSHIONS; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MAP KINASE KINASE KINASE 3; MESODERM; MICE; MORPHOGENESIS; TRANSFORMING GROWTH FACTOR BETA2;

EID: 58149394173     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.108.180752     Document Type: Article

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