A combination of ultrahigh throughput PathHunter and cytokine secretion assays to identify glucocorticoid receptor agonists

Analytical Biochemistry

Volumn 385, Issue 2, 2009, Pages 286-292

  Patel, Amita ^a   Murray, Justin ^a   McElwee Whitmer, Sheila ^a   Bai, Chang ^a   Kunapuli, Priya ^a   Johnson, Eric N ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Cytokine secretion; Glucocorticoid receptor; PathHunter; Ultrahigh throughput screen

Indexed keywords

PHYSIOLOGICAL MODELS; PHYSIOLOGY;

CYTOKINE SECRETIONS; FRAGMENT COMPLEMENTATION; FUNCTIONAL INFORMATION; GLUCOCORTICOID RECEPTOR; NUCLEAR TRANSLOCATIONS; PATHHUNTER; RECEPTOR ACTIVATION; SIGNAL-TO-BACKGROUND RATIO;

HORMONES;

CYTOKINE; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR ANTAGONIST; LIPOPOLYSACCHARIDE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MOLECULAR LIBRARY; MONOCYTE; NONHUMAN; PERFORMANCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

EID: 58149392973     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2008.11.005     Document Type: Article

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