Ethanol and arachidonic acid synergize to activate Kupffer cells and modulate the fibrogenic response via tumor necrosis factor α, reduced glutathione, and transforming growth factor β-dependent mechanisms

Hepatology

Volumn 48, Issue 6, 2008, Pages 2027-2039

  Cubero, Francisco Javier ^a   Nieto, Natalia ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ALPHA TOCOPHEROL; ARACHIDONIC ACID; BUTHIONINE SULFOXIMINE; DIPHENYLIODONIUM SALT; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; CENTRAL DEPRESSANT AGENT; COLLAGEN TYPE 1; UNSATURATED FATTY ACID;

ALCOHOL CONSUMPTION; ALCOHOL LIVER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL FUNCTION; CELL PROLIFERATION; COCULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; FIBROGENESIS; INFLAMMATION; KUPFFER CELL; LIPID PEROXIDATION; LIVER CELL; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; RAT; SPRAGUE DAWLEY RAT; STELLATE CELL; UPREGULATION; ANIMAL; APOPTOSIS; DISEASE MODEL; DRUG EFFECT; DRUG POTENTIATION; FEMALE; ITO CELL; LIVER CIRRHOSIS; METABOLISM; PATHOLOGY;

ANIMALS; APOPTOSIS; ARACHIDONIC ACID; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM DEPRESSANTS; COCULTURE TECHNIQUES; COLLAGEN TYPE I; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; ETHANOL; FATTY ACIDS, UNSATURATED; FEMALE; GLUTATHIONE; HEPATIC STELLATE CELLS; KUPFFER CELLS; LIVER CIRRHOSIS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 58149380812     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.22592     Document Type: Article

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