메뉴 건너뛰기




Volumn 86, Issue 10, 2008, Pages 1352-1360

Pancreatic islets induce CD4+CD25-Foxp3+ T-Cell regulated tolerance to HY-mismatched skin grafts

Author keywords

Diabetes; HY minor histocompatibility; Islet transplantation; Regulatory T cells; Tolerance

Indexed keywords

HY ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; STREPTOZOCIN; TRANSCRIPTION FACTOR FOXP3; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; LEUKOCYTE ANTIGEN; UNCLASSIFIED DRUG;

EID: 58149358850     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e31818aa43c     Document Type: Article
Times cited : (10)

References (42)
  • 1
    • 0021997185 scopus 로고
    • Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease
    • Sakaguchi S, Fukuma K, Kuribayashi K, et al. Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease. J Exp Med 1985; 161: 72.
    • (1985) J Exp Med , vol.161 , pp. 72
    • Sakaguchi, S.1    Fukuma, K.2    Kuribayashi, K.3
  • 2
    • 0035180065 scopus 로고    scopus 로고
    • Immunologic tolerance maintained by CD25 + CD4 + regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
    • Sakaguchi S, Sakaguchi N, Shimizu J, et al. Immunologic tolerance maintained by CD25 + CD4 + regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev 2001; 182: 18.
    • (2001) Immunol Rev , vol.182 , pp. 18
    • Sakaguchi, S.1    Sakaguchi, N.2    Shimizu, J.3
  • 3
    • 0037364804 scopus 로고    scopus 로고
    • Natural versus adaptive regulatory T cells
    • Bluestone JA, Abbas AK. Natural versus adaptive regulatory T cells. Nat Rev Immunol 2003; 3: 253.
    • (2003) Nat Rev Immunol , vol.3 , pp. 253
    • Bluestone, J.A.1    Abbas, A.K.2
  • 4
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25 + CD4+ regulatory T cells in immunological tolerance to self and non-self
    • Sakaguchi S. Naturally arising Foxp3-expressing CD25 + CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 2005; 6: 345.
    • (2005) Nat Immunol , vol.6 , pp. 345
    • Sakaguchi, S.1
  • 5
    • 0030704726 scopus 로고    scopus 로고
    • A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • Groux H, O'Garra A, Bigler M, et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997; 389: 737.
    • (1997) Nature , vol.389 , pp. 737
    • Groux, H.1    O'Garra, A.2    Bigler, M.3
  • 8
    • 0036122891 scopus 로고    scopus 로고
    • Tolerization of dendritic cells by T(S) cells: The crucial role of inhibitory receptors ILT3 and ILT4
    • Chang CC, Ciubotariu R, Manavalan JS, et al. Tolerization of dendritic cells by T(S) cells: The crucial role of inhibitory receptors ILT3 and ILT4. Nat Immunol 2002; 3: 237.
    • (2002) Nat Immunol , vol.3 , pp. 237
    • Chang, C.C.1    Ciubotariu, R.2    Manavalan, J.S.3
  • 9
    • 0033929005 scopus 로고    scopus 로고
    • Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression
    • Zhang ZX, Yang L, Young KJ, et al. Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression. Nat Med 2000; 6: 782.
    • (2000) Nat Med , vol.6 , pp. 782
    • Zhang, Z.X.1    Yang, L.2    Young, K.J.3
  • 10
    • 0035162560 scopus 로고    scopus 로고
    • Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
    • Brunkow ME, Jeffery EW, Hjerrild KA, et al. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat Genet 2001; 27: 68.
    • (2001) Nat Genet , vol.27 , pp. 68
    • Brunkow, M.E.1    Jeffery, E.W.2    Hjerrild, K.A.3
  • 11
    • 0035163909 scopus 로고    scopus 로고
    • X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
    • Wildin RS, Ramsdell F, Peake J, et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat Genet 2001; 27: 18.
    • (2001) Nat Genet , vol.27 , pp. 18
    • Wildin, R.S.1    Ramsdell, F.2    Peake, J.3
  • 12
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003; 4: 330.
    • (2003) Nat Immunol , vol.4 , pp. 330
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 13
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003; 299: 1057.
    • (2003) Science , vol.299 , pp. 1057
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 14
    • 0842278639 scopus 로고    scopus 로고
    • Antigen nonspecific suppression of T cell responses by activated stimulation-refractory CD4 + T cells
    • Duthoit CT, Nguyen P, Geiger TL. Antigen nonspecific suppression of T cell responses by activated stimulation-refractory CD4 + T cells. J Immunol 2004; 172: 2238.
    • (2004) J Immunol , vol.172 , pp. 2238
    • Duthoit, C.T.1    Nguyen, P.2    Geiger, T.L.3
  • 15
    • 0037108485 scopus 로고    scopus 로고
    • Generation ex vivo of TGF-betaproducing regulatory T cells from CD4+CD25-precursors
    • Zheng SG, GrayJD, OhtsukaK, et al. Generation ex vivo of TGF-betaproducing regulatory T cells from CD4+CD25-precursors. J Immunol 2002; 169: 4183.
    • (2002) J Immunol , vol.169 , pp. 4183
    • Zheng, S.G.1    Gray, J.D.2    Ohtsuka, K.3
  • 16
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25 - naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
    • Chen W, Jin W, Hardegen N, et al. Conversion of peripheral CD4+CD25 - naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 2003; 198: 1875.
    • (2003) J Exp Med , vol.198 , pp. 1875
    • Chen, W.1    Jin, W.2    Hardegen, N.3
  • 17
    • 8344275995 scopus 로고    scopus 로고
    • Crucial role of FOXP3 in the development and function of human CD25 + CD4 + regulatory T cells
    • Yagi H, Nomura T, Nakamura K, et al. Crucial role of FOXP3 in the development and function of human CD25 + CD4 + regulatory T cells. Int Immunol 2004; 16: 1643.
    • (2004) Int Immunol , vol.16 , pp. 1643
    • Yagi, H.1    Nomura, T.2    Nakamura, K.3
  • 18
    • 0034665514 scopus 로고    scopus 로고
    • CD25 is a marker for CD4+ thymocytes that prevent autoimmune diabetes in rats, but peripheral T cells with this function are found in both CD25 + and CD25 - subpopulations
    • Stephens LA, Mason D. CD25 is a marker for CD4+ thymocytes that prevent autoimmune diabetes in rats, but peripheral T cells with this function are found in both CD25 + and CD25 - subpopulations. J Immunol 2000; 165: 3105.
    • (2000) J Immunol , vol.165 , pp. 3105
    • Stephens, L.A.1    Mason, D.2
  • 19
    • 0036791004 scopus 로고    scopus 로고
    • Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25 - regulatory T cells
    • Lehmann J, Huehn J, de la Rosa M, et al. Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25 - regulatory T cells. Proc Natl Acad Sci USA 2002; 99: 13031.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13031
    • Lehmann, J.1    Huehn, J.2    de la Rosa, M.3
  • 20
    • 0036604283 scopus 로고    scopus 로고
    • Both CD4(+)CD25( + ) and CD4( + )CD25( - ) regulatory cells mediate dominant transplantation tolerance
    • Graca L, Thompson S, Lin CY, et al. Both CD4(+)CD25( + ) and CD4( + )CD25( - ) regulatory cells mediate dominant transplantation tolerance. J Immunol 2002; 168:5558.
    • (2002) J Immunol , vol.168 , pp. 5558
    • Graca, L.1    Thompson, S.2    Lin, C.Y.3
  • 21
    • 33748743615 scopus 로고    scopus 로고
    • Immune privilege induced by regulatory T cells in transplantation tolerance
    • Cobbold SP, Adams E, Graca L, et al. Immune privilege induced by regulatory T cells in transplantation tolerance. Immunol Rev 2006; 213: 239.
    • (2006) Immunol Rev , vol.213 , pp. 239
    • Cobbold, S.P.1    Adams, E.2    Graca, L.3
  • 22
    • 0030967156 scopus 로고    scopus 로고
    • Why do some females reject males? The molecular basis for male-specific graft rejection
    • Scott DM, Ehrmann IE, Ellis PS, et al. Why do some females reject males? The molecular basis for male-specific graft rejection. J Mol Med 1997; 75: 103.
    • (1997) J Mol Med , vol.75 , pp. 103
    • Scott, D.M.1    Ehrmann, I.E.2    Ellis, P.S.3
  • 23
    • 0036344353 scopus 로고    scopus 로고
    • Minor H antigens: Genes and peptides
    • Simpson E, Scott D, James E, et al. Minor H antigens: Genes and peptides. Transpl Immunol 2002; 10: 115.
    • (2002) Transpl Immunol , vol.10 , pp. 115
    • Simpson, E.1    Scott, D.2    James, E.3
  • 24
    • 0019825758 scopus 로고
    • Genetics of histocompatibility in mice. IV. Detection of certain minor (non-H-2) H antigens in selected organs by the popliteal node test
    • Johnson LL, Bailey DW, Mobraaten LE. Genetics of histocompatibility in mice. IV. Detection of certain minor (non-H-2) H antigens in selected organs by the popliteal node test. Immunogenetics 1981; 14: 63.
    • (1981) Immunogenetics , vol.14 , pp. 63
    • Johnson, L.L.1    Bailey, D.W.2    Mobraaten, L.E.3
  • 25
    • 0027486311 scopus 로고
    • The functional basis of minor histocompatibility loci
    • Roopenian DC, Davis AP, Christianson GJ, et al. The functional basis of minor histocompatibility loci. J Immunol 1993; 151: 4595.
    • (1993) J Immunol , vol.151 , pp. 4595
    • Roopenian, D.C.1    Davis, A.P.2    Christianson, G.J.3
  • 26
    • 10044223517 scopus 로고    scopus 로고
    • Role of CD4+ and CD8+ T cells in murine skin and heart allograft rejection across different antigenic desparities
    • Youssef AR, Otley C, Mathieson PW, et al. Role of CD4+ and CD8+ T cells in murine skin and heart allograft rejection across different antigenic desparities. Transpl Immunol 2004; 13: 297.
    • (2004) Transpl Immunol , vol.13 , pp. 297
    • Youssef, A.R.1    Otley, C.2    Mathieson, P.W.3
  • 27
    • 0033104692 scopus 로고    scopus 로고
    • Tolerance to antigen-presenting cell-depleted islet allografts is CD4 T cell dependent
    • Coulombe M, Yang H, Wolf LA, et al. Tolerance to antigen-presenting cell-depleted islet allografts is CD4 T cell dependent. J Immunol 1999; 162: 2503.
    • (1999) J Immunol , vol.162 , pp. 2503
    • Coulombe, M.1    Yang, H.2    Wolf, L.A.3
  • 28
    • 0026666567 scopus 로고
    • Systemic chimerism in human female recipients of male livers
    • Starzl TE, Demetris AJ, Trucco M, et al. Systemic chimerism in human female recipients of male livers. Lancet 1992; 340: 876.
    • (1992) Lancet , vol.340 , pp. 876
    • Starzl, T.E.1    Demetris, A.J.2    Trucco, M.3
  • 29
    • 0037062414 scopus 로고    scopus 로고
    • Allogeneic beta-islet cells correct diabetes and resist immune rejection
    • Pericin M, Althage A, Freigang S, et al. Allogeneic beta-islet cells correct diabetes and resist immune rejection. Proc Natl Acad Sci USA 2002; 99: 8203.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8203
    • Pericin, M.1    Althage, A.2    Freigang, S.3
  • 30
    • 0442276553 scopus 로고    scopus 로고
    • The VITAL assay: A versatile fluoro-metric technique for assessing CTL- and NKT-mediated cytotoxicity against multiple targets in vitro and in vivo
    • Hermans IF, Silk JD, Yang J, et al. The VITAL assay: A versatile fluoro-metric technique for assessing CTL- and NKT-mediated cytotoxicity against multiple targets in vitro and in vivo. J Immunol Methods 2004; 285: 25.
    • (2004) J Immunol Methods , vol.285 , pp. 25
    • Hermans, I.F.1    Silk, J.D.2    Yang, J.3
  • 31
    • 2342652841 scopus 로고    scopus 로고
    • Transplantation tolerance induced by intranasal administration of HY peptides
    • AQ
    • Chai JG, James E, Dewchand H, et al. Transplantation tolerance induced by intranasal administration of HY peptides. Blood 2004; 103: 3951. AQ
    • (2004) Blood , vol.103 , pp. 3951
    • Chai, J.G.1    James, E.2    Dewchand, H.3
  • 33
    • 28244481908 scopus 로고    scopus 로고
    • Millrain M, Scott D, Addey C, et al. Identification of the immunodominant HY H2-D(k) epitope and evaluation of the role of direct and indirect antigen presentation in HY responses. J Immunol 2005; 175: 7209.
    • Millrain M, Scott D, Addey C, et al. Identification of the immunodominant HY H2-D(k) epitope and evaluation of the role of direct and indirect antigen presentation in HY responses. J Immunol 2005; 175: 7209.
  • 34
    • 0030936986 scopus 로고    scopus 로고
    • Simpson E, Scott D, Chandler P. The male-specific histocompatibility antigen, HY: A history of transplantation, immune response genes, sex determination and expression cloning. Annu Rev Immunol 1997; 15: 39.
    • Simpson E, Scott D, Chandler P. The male-specific histocompatibility antigen, HY: A history of transplantation, immune response genes, sex determination and expression cloning. Annu Rev Immunol 1997; 15: 39.
  • 35
    • 0035477973 scopus 로고    scopus 로고
    • Examination of HY response: T cell expansion, immunodominance, and cross-priming revealed by HY tetramer analysis
    • Millrain M, Chandler P, Dazzi F, et al. Examination of HY response: T cell expansion, immunodominance, and cross-priming revealed by HY tetramer analysis. J Immunol 2001; 167: 3756.
    • (2001) J Immunol , vol.167 , pp. 3756
    • Millrain, M.1    Chandler, P.2    Dazzi, F.3
  • 36
    • 0018884742 scopus 로고
    • Successful allotransplantation of mouse pancreatic islets to nonimmunosuppressed recipients
    • Bowen KM, Andrus L, Lafferty KJ. Successful allotransplantation of mouse pancreatic islets to nonimmunosuppressed recipients. Diabetes 1980; 29(suppl 1): 98.
    • (1980) Diabetes , vol.29 , Issue.SUPPL. 1 , pp. 98
    • Bowen, K.M.1    Andrus, L.2    Lafferty, K.J.3
  • 37
    • 0019366833 scopus 로고
    • Survival of H-Y-incompatible endocrine grafts in mice and rats
    • Naji A, Frangipane L, Barker CF, et al. Survival of H-Y-incompatible endocrine grafts in mice and rats. Transplantation 1981; 31: 145.
    • (1981) Transplantation , vol.31 , pp. 145
    • Naji, A.1    Frangipane, L.2    Barker, C.F.3
  • 38
    • 0018761711 scopus 로고
    • Immune responses of diabetic animals. Direct immunosuppressant effects of streptozotocin in mice
    • Nichols WK, Spellman JB, Vann LL, et al. Immune responses of diabetic animals. Direct immunosuppressant effects of streptozotocin in mice. Diabetologia 1979; 16: 51.
    • (1979) Diabetologia , vol.16 , pp. 51
    • Nichols, W.K.1    Spellman, J.B.2    Vann, L.L.3
  • 39
    • 0032797556 scopus 로고    scopus 로고
    • Antigen presentation pathways for immunity to islet transplants. Relevance to immunoisolation
    • Gill RG. Antigen presentation pathways for immunity to islet transplants. Relevance to immunoisolation. Ann N Y Acad Sci 1999; 875: 255.
    • (1999) Ann N Y Acad Sci , vol.875 , pp. 255
    • Gill, R.G.1
  • 40
    • 0038325761 scopus 로고    scopus 로고
    • Inducible transgenic mice reveal resting dendritic cells as potent inducers of CD8+ T cell tolerance
    • Probst HC, Lagnel J, Kollias G, et al. Inducible transgenic mice reveal resting dendritic cells as potent inducers of CD8+ T cell tolerance. Immunity 2003; 18: 713.
    • (2003) Immunity , vol.18 , pp. 713
    • Probst, H.C.1    Lagnel, J.2    Kollias, G.3
  • 41
    • 0037124359 scopus 로고    scopus 로고
    • Identification of regulatory T cells in tolerated allografts
    • Graca L, Cobbold SP, Waldmann H. Identification of regulatory T cells in tolerated allografts. J Exp Med 2002; 195: 1641.
    • (2002) J Exp Med , vol.195 , pp. 1641
    • Graca, L.1    Cobbold, S.P.2    Waldmann, H.3
  • 42
    • 0035347514 scopus 로고    scopus 로고
    • Regulatory tolerance-mediating T cells in transplantation tolerance
    • Sawitzki B, Lehmann M, Ritter T, et al. Regulatory tolerance-mediating T cells in transplantation tolerance. Transplant Proc 2001; 33: 2092.
    • (2001) Transplant Proc , vol.33 , pp. 2092
    • Sawitzki, B.1    Lehmann, M.2    Ritter, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.