메뉴 건너뛰기




Volumn 56, Issue 21, 2008, Pages 9905-9910

Phytochemicals of apple peels: Isolation, structure elucidation, and their antiproliferative and antioxidant activities

Author keywords

Antioxidant; Antioxidant activities; Antiproliferative activities; Apples; Phytochemicals; Structure identification

Indexed keywords

MALUS X DOMESTICA;

EID: 58149343667     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf8015255     Document Type: Article
Times cited : (161)

References (38)
  • 1
    • 27844472511 scopus 로고    scopus 로고
    • Causes of cancer in the world: Comparative risk assessment of nine behavioural and environmental factors
    • Danaei. G.; Hoom, S. V.; Lopez, A. D.; Murray, C. J. L.; Ezzati, M. Causes of cancer in the world: comparative risk assessment of nine behavioural and environmental factors. Lancet 2005, 366, 1784-1793.
    • (2005) Lancet , vol.366 , pp. 1784-1793
    • Danaei, G.1    Hoom, S.V.2    Lopez, A.D.3    Murray, C.J.L.4    Ezzati, M.5
  • 2
    • 0028305595 scopus 로고
    • Diet and health: What should we eat?
    • Willett, W. C. Diet and health: what should we eat? Science 1994, 264, 532-537.
    • (1994) Science , vol.264 , pp. 532-537
    • Willett, W.C.1
  • 3
    • 0029568005 scopus 로고
    • Diet, nutrition, and avoidable cancer
    • Willett, W. C. Diet, nutrition, and avoidable cancer. Enpiron. Health Perspect. 1995, 103, 165-170.
    • (1995) Enpiron. Health Perspect , vol.103 , pp. 165-170
    • Willett, W.C.1
  • 4
    • 11144335228 scopus 로고    scopus 로고
    • Apple phytochemicals and their health benefits
    • Boyer, J.; Liu, R. H. Apple phytochemicals and their health benefits. Nutr. J. 2004, 3, 5.
    • (2004) Nutr. J , vol.3 , pp. 5
    • Boyer, J.1    Liu, R.H.2
  • 5
    • 0343458043 scopus 로고    scopus 로고
    • Antioxidant activity of fresh apples
    • Eberhardt, M. V.; Lee, C. Y.; Liu, R. H. Antioxidant activity of fresh apples. Nature 2000, 405, 903-904.
    • (2000) Nature , vol.405 , pp. 903-904
    • Eberhardt, M.V.1    Lee, C.Y.2    Liu, R.H.3
  • 7
    • 0001635956 scopus 로고    scopus 로고
    • Antioxidant and antiproliferative activites of selected New York apple cultivars
    • Liu, R. H.; Eberhardt, M. V.; Lee, C. Y. Antioxidant and antiproliferative activites of selected New York apple cultivars. N. Y. Fruit Qual. 2001, 9, 15-17.
    • (2001) N. Y. Fruit Qual , vol.9 , pp. 15-17
    • Liu, R.H.1    Eberhardt, M.V.2    Lee, C.Y.3
  • 8
    • 0037021625 scopus 로고    scopus 로고
    • Antioxidant and antiproliferative activities of common fruits
    • Sun, J.; Chu, Y. F.; Wu, X. Z.; Liu, R. H. Antioxidant and antiproliferative activities of common fruits. J. Agric Food Chem. 2002, 50, 7449-7454.
    • (2002) J. Agric Food Chem , vol.50 , pp. 7449-7454
    • Sun, J.1    Chu, Y.F.2    Wu, X.Z.3    Liu, R.H.4
  • 9
    • 0035177827 scopus 로고    scopus 로고
    • Phenol antioxidant quantity and quality in foods: Fruits
    • Vinson, J. A.: Su, X.; Zubik, L.; Bose, P. Phenol antioxidant quantity and quality in foods: fruits. J. Agric. Food Chem. 2001, 49, 5315-5321.
    • (2001) J. Agric. Food Chem , vol.49 , pp. 5315-5321
    • Vinson, J.A.1    Su, X.2    Zubik, L.3    Bose, P.4
  • 12
    • 0030068760 scopus 로고    scopus 로고
    • Flavonoid intake and coronary mortality in Finland: A cohort study
    • Knekt, P.; Jarvinen, R.; Reunanen, A.; Maatela. J. Flavonoid intake and coronary mortality in Finland: a cohort study. Br. Med. J. 1996, 312, 478-481.
    • (1996) Br. Med. J , vol.312 , pp. 478-481
    • Knekt, P.1    Jarvinen, R.2    Reunanen, A.3    Maatela, J.4
  • 13
    • 0035402252 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease and intake of catechins, flavonols. and flavones: The MORGEN Study
    • Tabak, C.; Arts, I. C. W.; Smit, H. A.; Heederik, D.; Kromhout, D. Chronic obstructive pulmonary disease and intake of catechins, flavonols. and flavones: the MORGEN Study. Am. J. Respir. Crit. Care Med. 2001, 164, 61-64.
    • (2001) Am. J. Respir. Crit. Care Med , vol.164 , pp. 61-64
    • Tabak, C.1    Arts, I.C.W.2    Smit, H.A.3    Heederik, D.4    Kromhout, D.5
  • 15
    • 0037433478 scopus 로고    scopus 로고
    • Antiproliferative activity of apples is not due to phenolic-induced hydrogen peroxide formation
    • Liu, R. H.; Sun, J. Antiproliferative activity of apples is not due to phenolic-induced hydrogen peroxide formation. J. Agric. Food Chem. 2003, 51, 1718-1723.
    • (2003) J. Agric. Food Chem , vol.51 , pp. 1718-1723
    • Liu, R.H.1    Sun, J.2
  • 16
    • 15444371406 scopus 로고    scopus 로고
    • Apples prevent mammary tumors in rats
    • Liu, R. H.; Liu. J.; Chen. B. Apples prevent mammary tumors in rats. J. Agric. Food Chem. 2005, 53, 2341-2343.
    • (2005) J. Agric. Food Chem , vol.53 , pp. 2341-2343
    • Liu, R.H.1    Liu, J.2    Chen, B.3
  • 17
    • 0037471604 scopus 로고    scopus 로고
    • Antioxidant activity of apple peels
    • Wolfe, K.; Wu, X. Z.; Liu, R. H. Antioxidant activity of apple peels. J. Agric. Food Chem. 2003, 51, 609-614.
    • (2003) J. Agric. Food Chem , vol.51 , pp. 609-614
    • Wolfe, K.1    Wu, X.Z.2    Liu, R.H.3
  • 18
    • 0344951109 scopus 로고    scopus 로고
    • Apple peels as a value-added food ingredient
    • Wolfe. K.; Liu, R. H. Apple peels as a value-added food ingredient. J. Agric. Food Chem. 2003, 51, 1676-1683.
    • (2003) J. Agric. Food Chem , vol.51 , pp. 1676-1683
    • Wolfe, K.1    Liu, R.H.2
  • 19
    • 34250659001 scopus 로고    scopus 로고
    • Triterpenoids isolated from apple peels have potent antiproliferative activity and may be responsible for apple's anticancer activity
    • He, X. J.; Liu. R. H. Triterpenoids isolated from apple peels have potent antiproliferative activity and may be responsible for apple's anticancer activity. J. Agric. Food Chem. 2007, 55, 4366-4370.
    • (2007) J. Agric. Food Chem , vol.55 , pp. 4366-4370
    • He, X.J.1    Liu, R.H.2
  • 20
    • 33750051385 scopus 로고    scopus 로고
    • Cranberry phytochemicals: Isolation, structure elucidation, and their antiproliferative and antioxidative activities
    • He. X. J.; Liu, R. H. Cranberry phytochemicals: isolation, structure elucidation, and their antiproliferative and antioxidative activities. J. Agric. Food Chem. 2006, 54, 7069-7074.
    • (2006) J. Agric. Food Chem , vol.54 , pp. 7069-7074
    • He, X.J.1    Liu, R.H.2
  • 21
    • 33644786887 scopus 로고    scopus 로고
    • (2 S*, 3 S*, 4R*, 5R*) -3, 4, 5-Trihydroxy-6- (hydroxymethyl) -3, 4, 5, 6-tetrahydro-2H-pyran-2-yl benzoate
    • He, X. J.; Lobkovsky, E.; Liu, R. H. (2 S*, 3 S*, 4R*, 5R*) -3, 4, 5-Trihydroxy-6- (hydroxymethyl) -3, 4, 5, 6-tetrahydro-2H-pyran-2-yl benzoate. Acta Crystallogr. 2006, E62, o471-o472.
    • (2006) Acta Crystallogr , vol.E62
    • He, X.J.1    Lobkovsky, E.2    Liu, R.H.3
  • 22
    • 33644543794 scopus 로고    scopus 로고
    • (R*) -Methyl 3-carboxy-2-hydroxypropanoate
    • He, X. J.; Lobkovsky. E.; Liu, R. H. (R*) -Methyl 3-carboxy-2-hydroxypropanoate. Acta Crystallogr. 2005, E61, o4104-o4106.
    • (2005) Acta Crystallogr , vol.E61
    • He, X.J.1    Lobkovsky, E.2    Liu, R.H.3
  • 24
    • 7444254075 scopus 로고    scopus 로고
    • Variet al. differences in phenolic content, and antioxidant and antiproliferative activities of onions
    • Yang. J.; Meyers, K. J.; van der Heide, J.; Liu, R. H. Variet al. differences in phenolic content, and antioxidant and antiproliferative activities of onions. J. Agric. Food Chem. 2004, 52, 6787-6793.
    • (2004) J. Agric. Food Chem , vol.52 , pp. 6787-6793
    • Yang, J.1    Meyers, K.J.2    van der Heide, J.3    Liu, R.H.4
  • 25
    • 33845973448 scopus 로고    scopus 로고
    • Cranberry phytochemical extracts induce cell cycle arrest and apoptosis in human MCF-7 breast cancer cells
    • Sun, J.; Liu, R. H. Cranberry phytochemical extracts induce cell cycle arrest and apoptosis in human MCF-7 breast cancer cells. Cancer Lett. 2006, 241. 124-134.
    • (2006) Cancer Lett , vol.241 , pp. 124-134
    • Sun, J.1    Liu, R.H.2
  • 26
    • 0028587328 scopus 로고
    • Hepatitis virus surface antigen induces nitric oxide synthesis in hepatocytes: Possible role in hepatocarcinogenesis
    • Liu, R. H.; Jacob, J. R.; Hotchkiss, J. H.: Cote, P. J.; Gerin, J. L.: Tennant, B. C. Hepatitis virus surface antigen induces nitric oxide synthesis in hepatocytes: possible role in hepatocarcinogenesis. Carcinogenesis 1994, 15, 2875-2877.
    • (1994) Carcinogenesis , vol.15 , pp. 2875-2877
    • Liu, R.H.1    Jacob, J.R.2    Hotchkiss, J.H.3    Cote, P.J.4    Gerin, J.L.5    Tennant, B.C.6
  • 27
    • 0027250184 scopus 로고
    • Synthesis of nitric oxide and nitrosamine by immortalized woodchuck hepatocytes
    • Liu, R. H.; Jacob, J. R.; Hotchkiss. J. H.; Tennant, B. C. Synthesis of nitric oxide and nitrosamine by immortalized woodchuck hepatocytes. Carcinogenesis 1993, 14, 1609-1613.
    • (1993) Carcinogenesis , vol.14 , pp. 1609-1613
    • Liu, R.H.1    Jacob, J.R.2    Hotchkiss, J.H.3    Tennant, B.C.4
  • 28
    • 24344469424 scopus 로고    scopus 로고
    • Rapid peroxyl radical scavenging capacity (PSC) assay for assessing both hydrophilic and lipophilic antioxidants
    • Adom, K. K.; Liu, R. H. Rapid peroxyl radical scavenging capacity (PSC) assay for assessing both hydrophilic and lipophilic antioxidants. J. Agric. Food Chem. 2005, 53, 6572-6580.
    • (2005) J. Agric. Food Chem , vol.53 , pp. 6572-6580
    • Adom, K.K.1    Liu, R.H.2
  • 29
    • 0034962067 scopus 로고    scopus 로고
    • 1. Triterpenes from Licania licaniaeflora
    • Braca, A.; Sortino, C.; Mendez, J.; Morelli, 1. Triterpenes from Licania licaniaeflora. Fitoterapia 2001, 72, 585-587.
    • (2001) Fitoterapia , vol.72 , pp. 585-587
    • Braca, A.1    Sortino, C.2    Mendez, J.3    Morelli4
  • 30
    • 0027476042 scopus 로고
    • The fluorine atom as a cation-stabilizing auxiliary in biomimetic polyene cyclizations. 4. Total synthesis of dl-β-amyrin
    • Johnson. W. S.; Plummer. M. S.; Reddy, S. P.; Bartlett, W. R. The fluorine atom as a cation-stabilizing auxiliary in biomimetic polyene cyclizations. 4. Total synthesis of dl-β-amyrin. J. Am. Chem. Soc. 1993, 115, 515-521.
    • (1993) J. Am. Chem. Soc , vol.115 , pp. 515-521
    • Johnson, W.S.1    Plummer, M.S.2    Reddy, S.P.3    Bartlett, W.R.4
  • 31
    • 0028248808 scopus 로고    scopus 로고
    • 13C NMR spectra of pentacyclic triterpenoids-a compilation and some salient features. Phytochemistry 1994, 37, 1517-1575.
    • 13C NMR spectra of pentacyclic triterpenoids-a compilation and some salient features. Phytochemistry 1994, 37, 1517-1575.
  • 32
    • 49549159866 scopus 로고
    • 13C chemical shifts in olean-12-enes and urs-12-enes as and aid to structural assignment
    • 13C chemical shifts in olean-12-enes and urs-12-enes as and aid to structural assignment. Tetrahedron Lett. 1974, 15, 2831-2834.
    • (1974) Tetrahedron Lett , vol.15 , pp. 2831-2834
    • Doddrell, D.M.1    Khong, P.W.2    Lewis, K.G.3
  • 33
    • 22144498407 scopus 로고
    • Studies on oxidation of triterpenoids Part Vll. Transformation of oleanane and ursane skeletons to 11α, 12α-oxidotriterpenoids with hydrogen peroxide and selenium dioxide and their carbon-13 NMR data
    • Pradhan, B. P.: Chakraborty, S. Studies on oxidation of triterpenoids Part Vll. Transformation of oleanane and ursane skeletons to 11α, 12α-oxidotriterpenoids with hydrogen peroxide and selenium dioxide and their carbon-13 NMR data. Tetrahedron 1987, 43, 4487-4495.
    • (1987) Tetrahedron , vol.43 , pp. 4487-4495
    • Pradhan, B.P.1    Chakraborty, S.2
  • 34
    • 0032078875 scopus 로고    scopus 로고
    • Menezes, F. S.: Borsatto, A. S.; Pereira, N. A.; Matos, F. J. A.; Kaplan, M. A. C. Chamaedrydiol, an ursane triterpene from Marsypianthes chamaedrys. iPhytochemistry 1998, 48, 323-325.
    • Menezes, F. S.: Borsatto, A. S.; Pereira, N. A.; Matos, F. J. A.; Kaplan, M. A. C. Chamaedrydiol, an ursane triterpene from Marsypianthes chamaedrys. iPhytochemistry 1998, 48, 323-325.
  • 35
    • 0037048738 scopus 로고    scopus 로고
    • Antioxidant activities and antitumor screening of extracts from cranberry fruit (Vaccinium macrocarpon)
    • Yan. X. J.; Murphy. B. T.; Hammond. G. B.; Vinson. J. A.; Neto. C. C. Antioxidant activities and antitumor screening of extracts from cranberry fruit (Vaccinium macrocarpon). J. Agric. Food Chem. 2002, 50, 5844-5849.
    • (2002) J. Agric. Food Chem , vol.50 , pp. 5844-5849
    • Yan, X.J.1    Murphy, B.T.2    Hammond, G.B.3    Vinson, J.A.4    Neto, C.C.5
  • 36
    • 0036369447 scopus 로고    scopus 로고
    • Kang, H. W.; Yu, K. W.; Jun, W. J.; Chang, 1. S.; Han, S. B.; Kim, H. Y.; Cho. H. Y. Isolation and characterization of alkyl peroxy radical scavenging compound from leaves of Lauras nobilis. Biol. Pharm. Bull. 2002, 25, 102-108.
    • Kang, H. W.; Yu, K. W.; Jun, W. J.; Chang, 1. S.; Han, S. B.; Kim, H. Y.; Cho. H. Y. Isolation and characterization of alkyl peroxy radical scavenging compound from leaves of Lauras nobilis. Biol. Pharm. Bull. 2002, 25, 102-108.
  • 37
    • 9744222928 scopus 로고    scopus 로고
    • Potential synergy of phytochemicals in cancer prevention: Mechanism of action
    • Liu, R. H. Potential synergy of phytochemicals in cancer prevention: mechanism of action. J. Nutr. 2004, 134, 3479S-3485S.
    • (2004) J. Nutr , vol.134
    • Liu, R.H.1
  • 38
    • 36148987289 scopus 로고    scopus 로고
    • Cellular antioxidant activity (CAA) assay for assessing antioxidants. foods, and dietary supplements
    • Wolfe, K. L.; Liu, R. H. Cellular antioxidant activity (CAA) assay for assessing antioxidants. foods, and dietary supplements. J. Agric. Food Chem. 2007, 55, 8896-8907.
    • (2007) J. Agric. Food Chem , vol.55 , pp. 8896-8907
    • Wolfe, K.L.1    Liu, R.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.