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Volumn 180, Issue 2, 2008, Pages 845-856

Secondary mutations correct fitness defects in Toxoplasma gondii with dinitroaniline resistance mutations

Author keywords

[No Author keywords available]

Indexed keywords

ANILINE DERIVATIVE; TUBULIN; DRUG DERIVATIVE; ETHAFLURALIN; NITROBENZENE DERIVATIVE; ORYZALIN; SULFANILAMIDE DERIVATIVE; TRIFLURALIN; TUBULIN MODULATOR; UNCLASSIFIED DRUG;

EID: 58149337610     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.108.092494     Document Type: Article
Times cited : (29)

References (70)
  • 1
    • 22544476838 scopus 로고    scopus 로고
    • Altered microtubule dynamics by expression of modified alpha-tubulin protein causes right-handed helical growth in transgenic Arabidopsis plants
    • ABE, T., and T. HASHIMOTO, 2005 Altered microtubule dynamics by expression of modified alpha-tubulin protein causes right-handed helical growth in transgenic Arabidopsis plants. Plant J. 43: 191-204.
    • (2005) Plant J , vol.43 , pp. 191-204
    • ABE, T.1    HASHIMOTO, T.2
  • 2
    • 1542351006 scopus 로고    scopus 로고
    • Microtubule defects and cell morphogenesis in the lefty1lefty2 tubulin mutant of Arabidopsis thaliana
    • ABE, T., S. THITAMADEE and T. HASHIMOTO, 2004 Microtubule defects and cell morphogenesis in the lefty1lefty2 tubulin mutant of Arabidopsis thaliana. Plant Cell Physiol. 45: 211-220.
    • (2004) Plant Cell Physiol , vol.45 , pp. 211-220
    • ABE, T.1    THITAMADEE, S.2    HASHIMOTO, T.3
  • 3
    • 0035665308 scopus 로고    scopus 로고
    • Dominant-lethal alpha-tubulin mutants defective in microtubule depolymerization in yeast
    • ANDERS, K. R., and D. BOTSTEIN, 2001 Dominant-lethal alpha-tubulin mutants defective in microtubule depolymerization in yeast. Mol. Biol. Cell 12: 3973-3986.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 3973-3986
    • ANDERS, K.R.1    BOTSTEIN, D.2
  • 4
    • 8444219613 scopus 로고    scopus 로고
    • Rare, highly pyrimethamine-resistant alleles of the Plasmodium falciparum dihydrofolate reductase gene from 5 African sites
    • BATES, S. J., P. A. WINSTANLEY, W. M. WATKINS, A. ALLOUECHE, J. BWIKA et al., 2004 Rare, highly pyrimethamine-resistant alleles of the Plasmodium falciparum dihydrofolate reductase gene from 5 African sites. J. Infect. Dis. 190: 1783-1792.
    • (2004) J. Infect. Dis , vol.190 , pp. 1783-1792
    • BATES, S.J.1    WINSTANLEY, P.A.2    WATKINS, W.M.3    ALLOUECHE, A.4    BWIKA, J.5
  • 5
    • 0037009241 scopus 로고    scopus 로고
    • Antileishmanial dinitroaniline sulfonamides with activity against parasite tubulin
    • BHATTACHARYA, G., M. M. SALEM and K. A. WERBOVETZ, 2002 Antileishmanial dinitroaniline sulfonamides with activity against parasite tubulin. Bioorg. Med. Chem. Lett. 12: 2395-2398.
    • (2002) Bioorg. Med. Chem. Lett , vol.12 , pp. 2395-2398
    • BHATTACHARYA, G.1    SALEM, M.M.2    WERBOVETZ, K.A.3
  • 7
    • 0032915701 scopus 로고    scopus 로고
    • Effects of the antitubulin drug trifluralin on the proliferation and metacyclogenesis of Trypanosoma cruzi epimastigotes
    • BOGITSH, B. J., O. L. MIDDLETON and R. RIBEIRO-RODRIGUES, 1999 Effects of the antitubulin drug trifluralin on the proliferation and metacyclogenesis of Trypanosoma cruzi epimastigotes. Parasitol. Res. 85: 475-480.
    • (1999) Parasitol. Res , vol.85 , pp. 475-480
    • BOGITSH, B.J.1    MIDDLETON, O.L.2    RIBEIRO-RODRIGUES, R.3
  • 8
    • 0023737790 scopus 로고
    • Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii
    • BURG, J. L., D. PERELMAN, L. H. KASPER, P. L. WARE and J. C. BOOTHROYD, 1988 Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii. J. Immunol. 141: 3584-3591.
    • (1988) J. Immunol , vol.141 , pp. 3584-3591
    • BURG, J.L.1    PERELMAN, D.2    KASPER, L.H.3    WARE, P.L.4    BOOTHROYD, J.C.5
  • 9
    • 0020016614 scopus 로고
    • Microtubule structure in Caenorhabditis elegans neurons
    • CHALFIE, M., 1982 Microtubule structure in Caenorhabditis elegans neurons. Cold Spring Harb. Symp. Quant. Biol. 46 (Pt 1): 255-261.
    • (1982) Cold Spring Harb. Symp. Quant. Biol , vol.46 , Issue.PART 1 , pp. 255-261
    • CHALFIE, M.1
  • 10
    • 0018385401 scopus 로고
    • Organization of neuronal microtubules in the nematode Caenorhabditis elegans
    • CHALFIE, M., and J. N. THOMSON, 1979 Organization of neuronal microtubules in the nematode Caenorhabditis elegans. J. Cell Biol. 82: 278-289.
    • (1979) J. Cell Biol , vol.82 , pp. 278-289
    • CHALFIE, M.1    THOMSON, J.N.2
  • 11
    • 0020061796 scopus 로고
    • Structural and functional diversity in the neuronal microtubules of Caenorhabditis elegans
    • CHALFIE, M., and J. N. THOMSON, 1982 Structural and functional diversity in the neuronal microtubules of Caenorhabditis elegans. J. Cell Biol. 93: 15-23.
    • (1982) J. Cell Biol , vol.93 , pp. 15-23
    • CHALFIE, M.1    THOMSON, J.N.2
  • 12
    • 0022857776 scopus 로고
    • Mutations affecting microtubule structure in Caenorhabditis elegans
    • CHALFIE, M., E. DEAN, E. REILLY, K. BUCK and J. N. THOMSON, 1986 Mutations affecting microtubule structure in Caenorhabditis elegans. J. Cell Sci. Suppl. 5: 257-271.
    • (1986) J. Cell Sci. Suppl , vol.5 , pp. 257-271
    • CHALFIE, M.1    DEAN, E.2    REILLY, E.3    BUCK, K.4    THOMSON, J.N.5
  • 13
    • 0025030523 scopus 로고
    • Inhibition of leishmanias but not host macrophages by the antitubulin herbicide trifluralin
    • CHAN, M. M., and D. FONG, 1990 Inhibition of leishmanias but not host macrophages by the antitubulin herbicide trifluralin. Science 249: 924-926.
    • (1990) Science , vol.249 , pp. 924-926
    • CHAN, M.M.1    FONG, D.2
  • 14
    • 0017708394 scopus 로고
    • Guanosinetriphosphatase activity of tubulin associated with microtubule assembly
    • DAVID-PFEUTY, T., H. P. ERICKSON and D. PANTALONI, 1977 Guanosinetriphosphatase activity of tubulin associated with microtubule assembly. Proc. Natl. Acad. Sci. USA 74: 5372-5376.
    • (1977) Proc. Natl. Acad. Sci. USA , vol.74 , pp. 5372-5376
    • DAVID-PFEUTY, T.1    ERICKSON, H.P.2    PANTALONI, D.3
  • 15
    • 61849143275 scopus 로고    scopus 로고
    • DELANO, W. L., 2002 The PyMOL Molecular Graphics System. http:// www.pymol.org.
    • (2002)
    • DELANO, W.L.1
  • 16
    • 0034711208 scopus 로고    scopus 로고
    • Cold adaptation of microtubule assembly and dynamics. Structural interpretation of primary sequence changes present in the alpha- and beta-tubulins of Antarctic fishes
    • DETRICH, H. W., III, S. K. PARKER, R. C. WILLIAMS, JR., E. NOGALES and K. H. DOWNING, 2000 Cold adaptation of microtubule assembly and dynamics. Structural interpretation of primary sequence changes present in the alpha- and beta-tubulins of Antarctic fishes. J. Biol. Chem. 275: 37038-37047.
    • (2000) J. Biol. Chem , vol.275 , pp. 37038-37047
    • DETRICH III, H.W.1    PARKER, S.K.2    WILLIAMS JR., R.C.3    NOGALES, E.4    DOWNING, K.H.5
  • 18
    • 0028799520 scopus 로고
    • Structural analysis of mutations in the Drosophila β2-tubulin isoform reveals regions in the β-tubulin molecular required for general and for tissue-specific microtubule functions
    • FACKENTHAL, J. D., J. A. HUTCHENS, F. R. TURNER and E. C. RAFF, 1995 Structural analysis of mutations in the Drosophila β2-tubulin isoform reveals regions in the β-tubulin molecular required for general and for tissue-specific microtubule functions. Genetics 139: 267-286.
    • (1995) Genetics , vol.139 , pp. 267-286
    • FACKENTHAL, J.D.1    HUTCHENS, J.A.2    TURNER, F.R.3    RAFF, E.C.4
  • 19
    • 0344826569 scopus 로고    scopus 로고
    • Fitness effects of DHFR-TS mutations associated with pyrimethamine resistance in apicomplexan parasites
    • FOHL, L. M., and D. S. ROOS, 2003 Fitness effects of DHFR-TS mutations associated with pyrimethamine resistance in apicomplexan parasites. Mol. Microbiol. 50: 1319-1327.
    • (2003) Mol. Microbiol , vol.50 , pp. 1319-1327
    • FOHL, L.M.1    ROOS, D.S.2
  • 20
    • 0033037583 scopus 로고    scopus 로고
    • MEC-12, an alpha-tubulin required for touch sensitivity in C. elegans
    • FUKUSHIGE, T., Z. K. SIDDIQUI, M. CHOU, J. G. CULOTTI, C. B. GOGONEA et al., 1999 MEC-12, an alpha-tubulin required for touch sensitivity in C. elegans. J. Cell Sci. 112(Pt 3): 395-403.
    • (1999) J. Cell Sci , vol.112 , Issue.PART 3 , pp. 395-403
    • FUKUSHIGE, T.1    SIDDIQUI, Z.K.2    CHOU, M.3    CULOTTI, J.G.4    GOGONEA, C.B.5
  • 21
    • 12944277104 scopus 로고    scopus 로고
    • A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells
    • GIANNAKAKOU, P., R. GUSSIO, E. NOGALES, K. H. DOWNING, D. ZAHAREVITZ et al., 2000 A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells. Proc. Natl. Acad. Sci. USA 97: 2904-2909.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 2904-2909
    • GIANNAKAKOU, P.1    GUSSIO, R.2    NOGALES, E.3    DOWNING, K.H.4    ZAHAREVITZ, D.5
  • 22
    • 0034664244 scopus 로고    scopus 로고
    • The 4 A X-ray structure of a tubulin:stathmin-like domain complex
    • GIGANT, B., P. A. CURMI, C. MARTIN- BARBEY, E. CHARBAUT, S. LACHKAR et al., 2000 The 4 A X-ray structure of a tubulin:stathmin-like domain complex. Cell 102: 809-816.
    • (2000) Cell , vol.102 , pp. 809-816
    • GIGANT, B.1    CURMI, P.A.2    MARTIN- BARBEY, C.3    CHARBAUT, E.4    LACHKAR, S.5
  • 23
    • 0029937237 scopus 로고    scopus 로고
    • Genetic interactions affecting touch sensitivity in Caenorhabditis elegans
    • GU, G., G. A. CALDWELL and M. CHALFIE, 1996 Genetic interactions affecting touch sensitivity in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 93: 6577-6582.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 6577-6582
    • GU, G.1    CALDWELL, G.A.2    CHALFIE, M.3
  • 24
    • 0037975662 scopus 로고    scopus 로고
    • Understanding tubulin-Taxol interactions: Mutations that impart Taxol binding to yeast tubulin
    • GUPTA, M. L., JR., C. J. BODE, G. I. GEORG and R. H. HIMES, 2003 Understanding tubulin-Taxol interactions: mutations that impart Taxol binding to yeast tubulin. Proc. Natl. Acad. Sci. USA 100: 6394-6397.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 6394-6397
    • GUPTA JR., M.L.1    BODE, C.J.2    GEORG, G.I.3    HIMES, R.H.4
  • 25
    • 0034844550 scopus 로고    scopus 로고
    • Novel alleles of the Plasmodium falciparum dhfr highly resistant to pyrimethamine and chlorcycloguanil, but not WR99210
    • HANKINS, E. G., D. C. WARHURST and C. H. SIBLEY, 2001 Novel alleles of the Plasmodium falciparum dhfr highly resistant to pyrimethamine and chlorcycloguanil, but not WR99210. Mol. Biochem. Parasitol. 117: 91-102.
    • (2001) Mol. Biochem. Parasitol , vol.117 , pp. 91-102
    • HANKINS, E.G.1    WARHURST, D.C.2    SIBLEY, C.H.3
  • 26
    • 0036881125 scopus 로고    scopus 로고
    • Highly pyrimethamine-resistant alleles of dihydrofolate reductase in isolates of Plasmodium falciparum from Tanzania
    • HASTINGS, M. D., S. J. BATES, E. A. BLACKSTONE, S. M. MONKS, T. K. MUTABINGWA et al., 2002 Highly pyrimethamine-resistant alleles of dihydrofolate reductase in isolates of Plasmodium falciparum from Tanzania. Trans. R. Soc. Trop. Med. Hyg. 96: 674-676.
    • (2002) Trans. R. Soc. Trop. Med. Hyg , vol.96 , pp. 674-676
    • HASTINGS, M.D.1    BATES, S.J.2    BLACKSTONE, E.A.3    MONKS, S.M.4    MUTABINGWA, T.K.5
  • 27
    • 0035523572 scopus 로고    scopus 로고
    • Mutations in {beta}-tubulin map to domains involved in regulation of microtubule stability in epothilone-resistant cell lines
    • HE, L., C.-P. HUANG YANG and S. B. HORWITZ, 2001 Mutations in {beta}-tubulin map to domains involved in regulation of microtubule stability in epothilone-resistant cell lines. Mol. Cancer Ther. 1: 3-10.
    • (2001) Mol. Cancer Ther , vol.1 , pp. 3-10
    • HE, L.1    HUANG YANG, C.-P.2    HORWITZ, S.B.3
  • 28
    • 0017366021 scopus 로고
    • Binding of the herbicide trifluralin to Chlamydomonas flagellar tubulin
    • HESS, F. D., and D. E. BAYER, 1977 Binding of the herbicide trifluralin to Chlamydomonas flagellar tubulin. J. Cell Sci. 24: 351-360.
    • (1977) J. Cell Sci , vol.24 , pp. 351-360
    • HESS, F.D.1    BAYER, D.E.2
  • 29
    • 0037128925 scopus 로고    scopus 로고
    • A novel polymer of tubulin forms the conoid of Toxoplasma gondii
    • HU, K., D. S. ROOS and J. M. MURRAY, 2002 A novel polymer of tubulin forms the conoid of Toxoplasma gondii. J. Cell Biol. 156: 1039-1050.
    • (2002) J. Cell Biol , vol.156 , pp. 1039-1050
    • HU, K.1    ROOS, D.S.2    MURRAY, J.M.3
  • 30
    • 0000032476 scopus 로고
    • Rapid and reversible high-affinity binding of the dinitroaniline herbicide oryzalin to tubulin from Zea mays L
    • HUGDAHL, J. D., and L. C. MOREJOHN, 1993 Rapid and reversible high-affinity binding of the dinitroaniline herbicide oryzalin to tubulin from Zea mays L. Plant Physiol. 102: 725-740.
    • (1993) Plant Physiol , vol.102 , pp. 725-740
    • HUGDAHL, J.D.1    MOREJOHN, L.C.2
  • 31
    • 34548414158 scopus 로고    scopus 로고
    • An Arabidopsis thaliana tubulin mutant with conditional root-skewing phenotype
    • ISHIDA, T., and T. HASHIMOTO, 2007 An Arabidopsis thaliana tubulin mutant with conditional root-skewing phenotype. J. Plant Res. 120: 635-640.
    • (2007) J. Plant Res , vol.120 , pp. 635-640
    • ISHIDA, T.1    HASHIMOTO, T.2
  • 32
    • 34347226330 scopus 로고    scopus 로고
    • Helical microtubule arrays in a collection of twisting tubulin mutants of Arabidopsis thaliana
    • ISHIDA, T., Y. KANEKO, M. IWANO and T. HASHIMOTO, 2007a Helical microtubule arrays in a collection of twisting tubulin mutants of Arabidopsis thaliana. Proc. Natl. Acad. Sci. USA 104: 8544-8549.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 8544-8549
    • ISHIDA, T.1    KANEKO, Y.2    IWANO, M.3    HASHIMOTO, T.4
  • 33
    • 33847318345 scopus 로고    scopus 로고
    • Twisted growth and organization of corticalmicrotubules
    • ISHIDA, T., S. THITAMADEE and T. HASHIMOTO, 2007b Twisted growth and organization of corticalmicrotubules. J. Plant Res. 120: 61-70.
    • (2007) J. Plant Res , vol.120 , pp. 61-70
    • ISHIDA, T.1    THITAMADEE, S.2    HASHIMOTO, T.3
  • 34
    • 0035815314 scopus 로고    scopus 로고
    • Optimized expression of green fluorescent protein in Toxoplasma gondii using thermostable green fluorescent protein mutants
    • KIM, K., M. S. EATON, W. SCHUBERT, S. WU and J. TANG, 2001 Optimized expression of green fluorescent protein in Toxoplasma gondii using thermostable green fluorescent protein mutants. Mol. Biochem. Parasitol. 113: 309-313.
    • (2001) Mol. Biochem. Parasitol , vol.113 , pp. 309-313
    • KIM, K.1    EATON, M.S.2    SCHUBERT, W.3    WU, S.4    TANG, J.5
  • 38
    • 0035834521 scopus 로고    scopus 로고
    • Refined structure of alpha beta-tubulin at 3.5 A resolution
    • LOWE, J., H. LI, K. H. DOWNING and E. NOGALES, 2001 Refined structure of alpha beta-tubulin at 3.5 A resolution. J. Mol. Biol. 313: 1045-1057.
    • (2001) J. Mol. Biol , vol.313 , pp. 1045-1057
    • LOWE, J.1    LI, H.2    DOWNING, K.H.3    NOGALES, E.4
  • 39
    • 37049001433 scopus 로고    scopus 로고
    • Mutations in {alpha}-tubulin confer dinitroaniline resistance at a cost to microtubule function
    • MA, C., C. LI, L. GANESAN, J. OAK, S. TSAI et al., 2007 Mutations in {alpha}-tubulin confer dinitroaniline resistance at a cost to microtubule function. Mol. Biol. Cell 18: 4711-4720.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 4711-4720
    • MA, C.1    LI, C.2    GANESAN, L.3    OAK, J.4    TSAI, S.5
  • 40
    • 0033917205 scopus 로고    scopus 로고
    • Effect of dinitroaniline herbicides on the growth of Entamoeba histolytica
    • MAKIOKA, A., M. KUMAGAI, H. OHTOMO, S. KOBAYASHI and T. TAKEUCHI, 2000 Effect of dinitroaniline herbicides on the growth of Entamoeba histolytica. J. Parasitol. 86: 607-610.
    • (2000) J. Parasitol , vol.86 , pp. 607-610
    • MAKIOKA, A.1    KUMAGAI, M.2    OHTOMO, H.3    KOBAYASHI, S.4    TAKEUCHI, T.5
  • 41
    • 33747451719 scopus 로고    scopus 로고
    • Binding and interaction of dinitroanilines with apicomplexan and kinetoplastid alpha-tubulin
    • MITRA, A., and D. SEPT, 2006 Binding and interaction of dinitroanilines with apicomplexan and kinetoplastid alpha-tubulin. J. Med. Chem. 49: 5226-5231.
    • (2006) J. Med. Chem , vol.49 , pp. 5226-5231
    • MITRA, A.1    SEPT, D.2
  • 42
    • 0033063875 scopus 로고    scopus 로고
    • Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations
    • MONZO, M., R. ROSELL, J. J. SANCHEZ, J. S. LEE, A. O'BRATE et al., 1999 Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations. J. Clin. Oncol. 17: 1786-1793.
    • (1999) J. Clin. Oncol , vol.17 , pp. 1786-1793
    • MONZO, M.1    ROSELL, R.2    SANCHEZ, J.J.3    LEE, J.S.4    O'BRATE, A.5
  • 43
    • 0000362063 scopus 로고    scopus 로고
    • MOREJOHN, L. C., T. E. BUREAU, J. MOLE- BAJER, A. S. BAJER and D. E. FOSKET, 1987 Oryzalin, a dinitroaniline herbicide, binds to plant tubulin and inhibits microtubule polymerization in vitro. Planta 172: 252-264.
    • MOREJOHN, L. C., T. E. BUREAU, J. MOLE- BAJER, A. S. BAJER and D. E. FOSKET, 1987 Oryzalin, a dinitroaniline herbicide, binds to plant tubulin and inhibits microtubule polymerization in vitro. Planta 172: 252-264.
  • 45
    • 0036500723 scopus 로고    scopus 로고
    • Disruption of microtubules uncouples budding and nuclear division in Toxoplasma gondii
    • MORRISSETTE, N. S., and L. D. SIBLEY, 2002b Disruption of microtubules uncouples budding and nuclear division in Toxoplasma gondii. J. Cell Sci. 115: 1017-1025.
    • (2002) J. Cell Sci , vol.115 , pp. 1017-1025
    • MORRISSETTE, N.S.1    SIBLEY, L.D.2
  • 46
    • 1642546217 scopus 로고    scopus 로고
    • Dinitroanilines bind alpha-tubulin to disrupt microtubules
    • MORRISSETTE, N. S., A. MITRA, D. SEPT and L. D. SIBLEY, 2004 Dinitroanilines bind alpha-tubulin to disrupt microtubules. Mol. Biol. Cell 15: 1960-1968.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 1960-1968
    • MORRISSETTE, N.S.1    MITRA, A.2    SEPT, D.3    SIBLEY, L.D.4
  • 47
    • 2442505707 scopus 로고    scopus 로고
    • SPIRAL1 encodes a plant-specific microtubule-localized protein required for directional control of rapidly expanding Arabidopsis cells
    • NAKAJIMA, K., I. FURUTANI, H. TACHIMOTO, H. MATSUBARA and T. HASHIMOTO, 2004 SPIRAL1 encodes a plant-specific microtubule-localized protein required for directional control of rapidly expanding Arabidopsis cells. Plant Cell 16: 1178-1190.
    • (2004) Plant Cell , vol.16 , pp. 1178-1190
    • NAKAJIMA, K.1    FURUTANI, I.2    TACHIMOTO, H.3    MATSUBARA, H.4    HASHIMOTO, T.5
  • 48
    • 33646243260 scopus 로고    scopus 로고
    • Role of the SPIRAL1 gene family in anisotropic growth of Arabidopsis thaliana
    • NAKAJIMA, K., T. KAWAMURA and T. HASHIMOTO, 2006 Role of the SPIRAL1 gene family in anisotropic growth of Arabidopsis thaliana. Plant Cell Physiol. 47: 513-522.
    • (2006) Plant Cell Physiol , vol.47 , pp. 513-522
    • NAKAJIMA, K.1    KAWAMURA, T.2    HASHIMOTO, T.3
  • 49
    • 33644853818 scopus 로고    scopus 로고
    • Structural intermediates in microtubule assembly and disassembly: How and why?
    • NOGALES, E., and H. W. WANG, 2006a Structural intermediates in microtubule assembly and disassembly: How and why? Curr. Opin. Cell Biol. 18: 179-184.
    • (2006) Curr. Opin. Cell Biol , vol.18 , pp. 179-184
    • NOGALES, E.1    WANG, H.W.2
  • 50
    • 33646494080 scopus 로고    scopus 로고
    • Structural mechanisms underlying nucleotide-dependent self-assembly of tubulin and its relatives
    • NOGALES, E., and H. W. WANG, 2006b Structural mechanisms underlying nucleotide-dependent self-assembly of tubulin and its relatives. Curr. Opin. Struct. Biol. 16: 221-229.
    • (2006) Curr. Opin. Struct. Biol , vol.16 , pp. 221-229
    • NOGALES, E.1    WANG, H.W.2
  • 51
    • 0031010399 scopus 로고    scopus 로고
    • Visualizing the secondary structure of tubulin: Three-dimensional map at 4 A
    • NOGALES, E., S. G. WOLF and K. H. DOWNING, 1997 Visualizing the secondary structure of tubulin: three-dimensional map at 4 A. J. Struct. Biol. 118: 119-127.
    • (1997) J. Struct. Biol , vol.118 , pp. 119-127
    • NOGALES, E.1    WOLF, S.G.2    DOWNING, K.H.3
  • 55
    • 0031817512 scopus 로고    scopus 로고
    • Identification of novel temperature-sensitive lethal alleles in essential beta-tubulin and nonessential alpha 2-tubulin genes as fission yeast polarity mutants
    • RADCLIFFE, P., D. HIRATA, D. CHILDS, L. VARDY and T. TODA, 1998 Identification of novel temperature-sensitive lethal alleles in essential beta-tubulin and nonessential alpha 2-tubulin genes as fission yeast polarity mutants. Mol. Biol. Cell 9: 1757-1771.
    • (1998) Mol. Biol. Cell , vol.9 , pp. 1757-1771
    • RADCLIFFE, P.1    HIRATA, D.2    CHILDS, D.3    VARDY, L.4    TODA, T.5
  • 56
  • 58
    • 0028709114 scopus 로고
    • Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondii
    • ROOS, D. S., R. G. DONALD, N. S. MORRISSETTE and A. L. MOULTON, 1994 Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondii. Methods Cell Biol. 45: 27-63.
    • (1994) Methods Cell Biol , vol.45 , pp. 27-63
    • ROOS, D.S.1    DONALD, R.G.2    MORRISSETTE, N.S.3    MOULTON, A.L.4
  • 59
    • 0028985927 scopus 로고
    • beta-Tubulin mutation suppresses microtubule dynamics in vitro and slows mitosis in vivo
    • SAGE, C. R., A. S. DAVIS, C. A. DOUGHERTY, K. SULLIVAN and K. W. FARRELL, 1995a beta-Tubulin mutation suppresses microtubule dynamics in vitro and slows mitosis in vivo. Cell Motil. Cytoskeleton 30: 285-300.
    • (1995) Cell Motil. Cytoskeleton , vol.30 , pp. 285-300
    • SAGE, C.R.1    DAVIS, A.S.2    DOUGHERTY, C.A.3    SULLIVAN, K.4    FARRELL, K.W.5
  • 60
    • 0029079135 scopus 로고
    • Site-directed mutagenesis of putative GTP-binding sites of yeast beta-tubulin: Evidence that alpha-, beta-, and gamma-tubulins are atypical GTPases
    • SAGE, C. R., C. A. DOUGHERTY, A. S. DAVIS, R. G. BURNS, L. WILSON et al., 1995b Site-directed mutagenesis of putative GTP-binding sites of yeast beta-tubulin: evidence that alpha-, beta-, and gamma-tubulins are atypical GTPases. Biochemistry 34: 7409-7419.
    • (1995) Biochemistry , vol.34 , pp. 7409-7419
    • SAGE, C.R.1    DOUGHERTY, C.A.2    DAVIS, A.S.3    BURNS, R.G.4    WILSON, L.5
  • 61
    • 0024688962 scopus 로고
    • mec-7 is a beta-tubulin gene required for the production of 15-protofilament microtubules in Caenorhabditis elegans
    • SAVAGE, C., M. HAMELIN, J. G. CULOTTI, A. COULSON, D. G. ALBERTSON et al., 1989 mec-7 is a beta-tubulin gene required for the production of 15-protofilament microtubules in Caenorhabditis elegans. Genes Dev. 3: 870-881.
    • (1989) Genes Dev , vol.3 , pp. 870-881
    • SAVAGE, C.1    HAMELIN, M.2    CULOTTI, J.G.3    COULSON, A.4    ALBERTSON, D.G.5
  • 62
    • 0028133187 scopus 로고
    • Mutations in the Caenorhabditis elegans beta-tubulin gene mec-7: Effects on microtubule assembly and stability and on tubulin autoregulation
    • SAVAGE, C., Y. XUE, S. MITANI, D. HALL, R. ZAKHARY et al., 1994 Mutations in the Caenorhabditis elegans beta-tubulin gene mec-7: effects on microtubule assembly and stability and on tubulin autoregulation. J. Cell Sci. 107(Pt 8): 2165-2175.
    • (1994) J. Cell Sci , vol.107 , Issue.PART 8 , pp. 2165-2175
    • SAVAGE, C.1    XUE, Y.2    MITANI, S.3    HALL, D.4    ZAKHARY, R.5
  • 63
    • 16644366267 scopus 로고    scopus 로고
    • Plant-specific microtubule-associated protein SPIRAL2 is required for anisotropic growth in Arabidopsis
    • SHOJI, T., N. N. NARITA, K. HAYASHI, J. ASADA, T. HAMADA et al., 2004 Plant-specific microtubule-associated protein SPIRAL2 is required for anisotropic growth in Arabidopsis. Plant Physiol. 136: 3933-3944.
    • (2004) Plant Physiol , vol.136 , pp. 3933-3944
    • SHOJI, T.1    NARITA, N.N.2    HAYASHI, K.3    ASADA, J.4    HAMADA, T.5
  • 65
    • 0037046524 scopus 로고    scopus 로고
    • Microtubule basis for left-handed helical growth in Arabidopsis
    • THITAMADEE, S., K. TUCHIHARA and T. HASHIMOTO, 2002 Microtubule basis for left-handed helical growth in Arabidopsis. Nature 417: 193-196.
    • (2002) Nature , vol.417 , pp. 193-196
    • THITAMADEE, S.1    TUCHIHARA, K.2    HASHIMOTO, T.3
  • 67
    • 39049183967 scopus 로고    scopus 로고
    • Malaria. Chloroquine makes a comeback
    • VOGEL, G., 2006 Malaria. Chloroquine makes a comeback. Science 314: 904.
    • (2006) Science , vol.314 , pp. 904
    • VOGEL, G.1
  • 68
    • 20544463212 scopus 로고    scopus 로고
    • Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly
    • WANG, H. W., and E. NOGALES, 2005 Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly. Nature 435: 911-915.
    • (2005) Nature , vol.435 , pp. 911-915
    • WANG, H.W.1    NOGALES, E.2
  • 69
    • 25444519945 scopus 로고    scopus 로고
    • Assembly of GMPCPP-bound tubulin into helical ribbons and tubes and effect of colchicine
    • WANG, H. W., S. LONG, K. R. FINLEY and E. NOGALES, 2005 Assembly of GMPCPP-bound tubulin into helical ribbons and tubes and effect of colchicine. Cell Cycle 4: 1157-1160.
    • (2005) Cell Cycle , vol.4 , pp. 1157-1160
    • WANG, H.W.1    LONG, S.2    FINLEY, K.R.3    NOGALES, E.4
  • 70
    • 3142663907 scopus 로고    scopus 로고
    • Intra-allelic suppression of a mutation that stabilizes microtubules and confers resistance to colcemid
    • WANG, Y., S. VEERARAGHAVAN and F. CABRAL, 2004 Intra-allelic suppression of a mutation that stabilizes microtubules and confers resistance to colcemid. Biochemistry 43: 8965-8973.
    • (2004) Biochemistry , vol.43 , pp. 8965-8973
    • WANG, Y.1    VEERARAGHAVAN, S.2    CABRAL, F.3


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