Assembly of GMPCPP-bound tubulin into helical ribbons and tubes and effect of colchicine

Cell Cycle

Volumn 4, Issue 9, 2005, Pages 1157-1160

  Wang, Hong Wei ^a,c   Long, Sydney ^b   Finley, K Rose ^c   Nogales, Eva ^a,b  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Colchicine; Dynamic instability; Electron microscopy; GMPCPP; Microtubules; Tubulin

Indexed keywords

COLCHICINE; GUANOSINE PHOSPHATE; TUBULIN;

HUMAN; LOW TEMPERATURE; MICROTUBULE ASSEMBLY; NONHUMAN; POLYMERIZATION; PROTEIN ASSEMBLY; PROTEIN STABILITY; REVIEW;

EID: 25444519945     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.4.9.2042     Document Type: Review

References (19)

1. Desai A, Mitchison TJ. Microtubule polymerization dynamics. Ann Rev Dev Biol 1997; 13:83-117.
2. Hamel E. Microtubule Inhibitors. Pergamon Press, 1992.
3. Heald R, Nogales E. Microtubule dynamics. J Cell Sci 2002; V115:3-4.
4. Carlier MF, Hill TL, Chen Y-D. Interfernce of GTP hydrolysis in the mechanism of microtubule assembly: An experimental study. Proc Natl Acad Sci USA 1984; 81:771-5.
5. Nogales E, Wolf SG, Downing KH. Structure of the αβ tubulin dimer by electron crystallography. Nature 1998; 391:199-203.
6. Nogales E, Downing KH, Amos LA, Löwe J. Tubulin and FtsZ form a distinct family of GTPases. Nature Struc Biol 1998; 5:451-8.
7. Lowe J, Li H, Downing KH, Nogales E. Refined structure of alpha beta-tubulin at 3.5 A resolution. Journal of Molecular Biology 2001; V313:1045-57.
8. Nogales E, Whittaker M, Milligan RA, Downing KH. High resolution structure of the microtubule. Cell 1999; 96:79-88.
9. Li H, DeRosier DJ, Nicholson WV, Nogales E, Downing KH. Microtubule structure at 8 A resolution. Structure (Camb) 2002; 10:1317-28.
10. Ravelli RB, Gigant B, Curmi PA, Jourdain I, Lachkar S, Sobel A, Knossow M. Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain. Nature 2004; 428:198-202.
11. Wang HW, Nogales E. Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly. Nature 2005; 435:911-5.
12. Chrétien D, Fuller SD, Karsenti E. Structure of growing microtubule ends: Two-dimensional sheets close into tubes at variable rates. J Cell Biol 1995; 129:1311-28.
13. Hyman AA, Salser S, Drechsel DN, Unwin N, Mitchison TJ. Role of GTP hydrolysis in microtubule dynamics: Information from a slowly hydrolyzable analogue, GMPCPP. Mol Biol Cell 1992; 3:1155-67.
14. Hyman AA, Chretien D, Arnal I, Wade RH. Structural changes accompanying GTP hydrolysis in microtubules: Information from a slowly hydrolyzable analogue guanylyl-(alpha,beta)-methylene-diphosphonate. J Cell Biol 1995; 128:117-25.
15. Diaz JF, Valpuesta JM, Chacon P, Diakun G, Andreu JM. Changes made in microtubule protofilament number induced by taxol binding to an easily accessible site. J Biol Chem 1998; 273:33803-10.
16. Wolff J. Promotion of microtubule assembly by oligocations: Cooperativity between charged groups. Biochemistry 1998; 37:10722-9.
17. White EA, Burton PR, Himes RH. Polymorphic assembly of subtilisin-cleaved tubulin. Cell motylity and the ctoskeleton 1987; 7:31-8.
18. Unger E, Böhm JK, Vater W. Structural diversity and dynamics of microtubules and polymorphic tubulin assemblies. Electron Microsc Rev 1990; 3:355-95.
19. Westermann S, Avila-Sakar A, Wang HW, Niederstrasser H, Wong J, Drubin DG, Nogales E, Barnes G. Formation of a dynamic kinetochore Microtubule interface through assembly of the Dam1 ring complex. Mol Cell 2005; 17:277-90.