Comparison of immunotoxicity among tetrachloro-, pentachloro-, tetrabromo- and pentabromo-dibenzo-p-dioxins in mice

Toxicology

Volumn 256, Issue 1-2, 2009, Pages 25-31

  Ao, Kana ^a   Suzuki, Takehiro ^a   Murai, Hikari ^a   Matsumoto, Michiyo ^a   Nagai, Haruko ^a   Miyamoto, Yoshimi ^a   Tohyama, Chiharu ^b   Nohara, Keiko ^a  

^a NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

1,2,3,7,8 Pentabromodibenzo p dioxin (PeBDD); 2,3,7,8 Tetrabromodibenzo p dioxin (TBDD); Brominated dioxins; IL 5; Immunotoxicity

Indexed keywords

1,2,3,7,8 PENTABROMODIBENZO 4 DIOXIN; 1,2,3,7,8 PENTACHLORODIBENZO 4 DIOXIN; 2,3,7,8 TETRABROMODIBENZO 4 DIOXIN; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CYTOCHROME P450 1A1; DIOXIN; INTERLEUKIN 5; OVALBUMIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; FEMALE; IMMUNIZATION; IMMUNOTOXICITY; LIVER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN; SPLEEN CELL;

ANIMALS; CYTOCHROME P-450 CYP1A1; DIOXINS; FEMALE; IMMUNE SYSTEM DISEASES; IMMUNOGLOBULIN M; INTERLEUKIN-5; LIVER; MICE; MICE, INBRED C57BL; OVALBUMIN; RECEPTORS, ARYL HYDROCARBON; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPLEEN; T-LYMPHOCYTES;

MUS;

EID: 58149231142     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2008.10.024     Document Type: Article

References (28)

1. Birnbaum L.S., Staskal D.F., and Diliberto J.J. Health effects of polybrominated dibenzo-p-dioxins (PBDDs) and dibenzofurans (PBDFs). Environ. Int. 29 (2003) 855-860
2. Cormier S.A., Lomnicki S., Backes W., and Dellinger B. Origin and health impacts of emissions of toxic by-products and fine particles from combustion and thermal treatment of hazardous wastes and materials. Environ. Health Perspect. 114 (2006) 810-817
3. De Heer C., Verlaan A.P., Penninks A.H., Vos J.G., Schuurman H.J., and Van Loveren H. Time course of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced thymic atrophy in the Wistar rat. Toxicol. Appl. Pharmacol. 128 (1994) 97-104
4. DeVito M.J., Diliberto J.J., Ross D.G., Menache M.G., and Birnbaum L.S. Dose-response relationships for polyhalogenated dioxins and dibenzofurans following subchronic treatment in mice. Toxicol. Appl. Pharmacol. 147 (1997) 267-280
5. Inouye K., Ito T., Fujimaki H., Takahashi Y., Takemori T., Pan X., Tohyama C., and Nohara K. Suppressive effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the high-affinity antibody response in C57BL/6 mice. Toxicol. Sci. 74 (2003) 315-324
6. Inouye K., Pan X., Imai N., Ito T., Takei T., Tohyama C., and Nohara K. T cell-derived IL-5 production is a sensitive target of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Chemosphere 60 (2005) 907-913
7. Ito T., Inouye K., Fujimaki H., Tohyama C., and Nohara K. Mechanism of TCDD-induced suppression of antibody production: effect on T cell-derived cytokine production in the primary immune reaction of mice. Toxicol. Sci. 70 (2002) 46-54
8. Johnson C.W., Williams W.C., Copeland C.B., DeVito M.J., and Smialowicz R.J. Sensitivity of the SRBC PFC assay versus ELISA for detection of immunosuppression by TCDD and TCDD-like congeners. Toxicology 156 (2000) 1-11
9. Jordan M.B., Mills D.M., Kappler J., Marrack P., and Cambier J.C. Promotion of B cell immune responses via an alum-induced myeloid cell population. Science 304 (2004) 1808-1810
10. Kende A.S., and Wade J.J. Synthesis of new steric and electronic analogs of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Environ. Health Perspect. 5 (1973) 49-57
11. Kerkvliet N.I. Recent advances in understanding the mechanisms of TCDD immunotoxicity. Int. Immunopharmacol. 2 (2002) 277-291
12. Kool M., Soullié T., van Nimwegen M., Willart M.A., Muskens F., Jung S., Hoogsteden H.C., Hammad H., and Lambrecht B.N. Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells. J. Exp. Med. 205 (2008) 869-882
13. Li H., Yu L., Sheng G., Fu J., and Peng P. Severe PCDD/F and PBDD/F pollution in air around an electronic waste dismantling area in China. Environ. Sci. Technol. 41 (2007) 5641-5646
14. Luster M.I., Portier C., Pait D.G., White Jr. K.L., Gennings C., Munson A.E., and Rosenthal G.J. Risk assessment in immunotoxicology. I. Sensitivity and predictability of immune tests. Fundam. Appl. Toxicol. 18 (1992) 200-210
15. Mason G., Zacharewski T., Denomme M.A., Safe L., and Safe S. Polybrominated dibenzo-p-dioxins and related compounds: quantitative in vivo and in vitro structure-activity relationships. Toxicology 44 (1987) 245-255
16. Mennear J.H., and Lee C.C. Polybrominated dibenzo-p-dioxins and dibenzofurans: literature review and health assessment. Environ. Health Perspect. 102 Suppl. 1 (1994) 265-274
17. Nohara K., Fujimaki H., Tsukumo S., Inouye K., Sone H., and Tohyama C. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on T cell-derived cytokine production in ovalbumin (OVA)-immunized C57Bl/6 mice. Toxicology 172 (2002) 49-58
18. Nohara K., Ao K., Miyamoto Y., Ito T., Suzuki T., Toyoshiba H., and Tohyama C. Comparison of the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced CYP1A1 gene expression profile in lymphocytes from mice, rats, and humans: most potent induction in humans. Toxicology 225 (2006) 204-213
19. Okey A.B. An aryl hydrocarbon receptor odyssey to the shores of toxicology: the Deichmann Lecture, International Congress of Toxicology-XI. Toxicol. Sci. 98 (2007) 5-38
20. Olsman H., Engwall M., Kammann U., Klempt M., Otte J., van Bavel B., and Hollert H. Relative differences in aryl hydrocarbon receptor-mediated response for 18 polybrominated and mixed halogenated dibenzo-p-dioxins and -furans in cell lines from four different species. Environ. Toxicol. Chem. 26 (2007) 2448-2454
21. Pan X., Inouye K., Ito T., Nagai H., Takeuchi Y., Miyabara Y., Tohyama C., and Nohara K. Evaluation of relative potencies of PCB126 and PCB169 for the immunotoxicities in ovalbumin (OVA)-immunized mice. Toxicology 204 (2004) 51-60
22. Sakai S., Watanabe J., Honda Y., Takatsuki H., Aoki I., Futamatsu M., and Shiozaki K. Combustion of brominated flame retardants and behavior of its byproducts. Chemosphere 42 (2001) 519-531
23. Schmidt J.V., and Bradfield C.A. Ah receptor signaling pathways. Annu. Rev. Cell Dev. Biol. 12 (1996) 55-89
24. Smialowicz R.J., DeVito M.J., Williams W.C., and Birnbaum L.S. Relative potency based on hepatic enzyme induction predicts immunosuppressive effects of a mixture of PCDDs/PCDFs and PCBs. Toxicol. Appl. Pharmacol. 227 (2008) 477-484
25. Van den Berg M., Birnbaum L., Bosveld A.T., Brunstrom B., Cook P., Feeley M., Giesy J.P., Hanberg A., Hasegawa R., Kennedy S.W., Kubiak T., Larsen J.C., van Leeuwen F.X., Liem A.K., Nolt C., Peterson R.E., Poellinger L., Safe S., Schrenk D., Tillitt D., Tysklind M., Younes M., Waern F., and Zacharewski T. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife. Environ. Health Perspect. 106 (1998) 775-792
26. Van den Berg M., Birnbaum L.S., Denison M., De Vito M., Farland W., Feeley M., Fiedler H., Hakansson H., Hanberg A., Haws L., Rose M., Safe S., Schrenk D., Tohyama C., Tritscher A., Tuomisto J., Tysklind M., Walker N., and Peterson R.E. The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol. Sci. 93 (2006) 223-241
27. Weber L.W.D., and Greim H. The toxicity of brominated and mixed-halogenated dibenzo-p-dioxins and dibenzofurans: an overview. J. Toxicol. Environ. Health 50 (1997) 195-215
28. World Health Organization (WHO). Polybrominated dibenzo-p-dioxins and dibenzofurans. Environ. Health Criteria 205 (1998) (Geneva)