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Volumn 209, Issue 2, 2006, Pages 166-173

Expression and regulation of human β-defensin-2 in osteoarthritic cartilage

Author keywords

Antimicrobial peptides; Cartilage; Cytokines; Defensins; Gene regulation; Inflammation; Osteoarthritis

Indexed keywords

BETA DEFENSIN 2; CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

EID: 33744496298     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.1974     Document Type: Article
Times cited : (36)

References (29)
  • 1
    • 0033712395 scopus 로고    scopus 로고
    • The role of the chondrocyte in osteoarthritis
    • Goldring MB. The role of the chondrocyte in osteoarthritis. Arthritis Rheum 2000;43:1916-1926.
    • (2000) Arthritis Rheum , vol.43 , pp. 1916-1926
    • Goldring, M.B.1
  • 2
    • 0034971296 scopus 로고    scopus 로고
    • Osteoarthritis, an inflammatory disease: Potential implication for the selection of new therapeutic targets
    • Pelletier JP, Martel-Pelletier J, Abramson SB. Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets. Arthritis Rheum 2001;44:1237-1247.
    • (2001) Arthritis Rheum , vol.44 , pp. 1237-1247
    • Pelletier, J.P.1    Martel-Pelletier, J.2    Abramson, S.B.3
  • 3
    • 0037165196 scopus 로고    scopus 로고
    • Antimicrobial peptides of multicellular organisms
    • Zasloff M. Antimicrobial peptides of multicellular organisms. Nature 2002;415:389-395.
    • (2002) Nature , vol.415 , pp. 389-395
    • Zasloff, M.1
  • 6
    • 0034125829 scopus 로고    scopus 로고
    • Mucoid Pseudomonas aeruginosa, TNF-alpha, and IL-1-beta, but not IL-6, induce human beta-defensin-2 in respiratory epithelia
    • Harder J, Meyer-Hoffert U, Teran LM, Schwichtenberg L, Bartels J, Maune S, et al. Mucoid Pseudomonas aeruginosa, TNF-alpha, and IL-1-beta, but not IL-6, induce human beta-defensin-2 in respiratory epithelia. Am J Respir Cell Mol Biol 2000;22:714-721.
    • (2000) Am J Respir Cell Mol Biol , vol.22 , pp. 714-721
    • Harder, J.1    Meyer-Hoffert, U.2    Teran, L.M.3    Schwichtenberg, L.4    Bartels, J.5    Maune, S.6
  • 7
    • 0035936156 scopus 로고    scopus 로고
    • Innate antimicrobial peptide protects the skin from invasive bacterial infection
    • Nizet V, Ohtake T, Lauth X, Trowbridge J, Rudisill J, Dorschner RA, et al. Innate antimicrobial peptide protects the skin from invasive bacterial infection. Nature 2001;414:454-457.
    • (2001) Nature , vol.414 , pp. 454-457
    • Nizet, V.1    Ohtake, T.2    Lauth, X.3    Trowbridge, J.4    Rudisill, J.5    Dorschner, R.A.6
  • 8
    • 0037218616 scopus 로고    scopus 로고
    • By IL-1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide
    • Liu L, Roberts AA, Ganz T. By IL-1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide. J Immunol 2003;170:575-580.
    • (2003) J Immunol , vol.170 , pp. 575-580
    • Liu, L.1    Roberts, A.A.2    Ganz, T.3
  • 9
    • 0034828007 scopus 로고    scopus 로고
    • Expression of natural peptide antibiotics in human articular cartilage and synovial membrane
    • Paulsen F, Pufe T, Petersen W, Tillmann B. Expression of natural peptide antibiotics in human articular cartilage and synovial membrane. Clin Diagn Lab Immunol 2001;8:1021-1023.
    • (2001) Clin Diagn Lab Immunol , vol.8 , pp. 1021-1023
    • Paulsen, F.1    Pufe, T.2    Petersen, W.3    Tillmann, B.4
  • 10
    • 0036841956 scopus 로고    scopus 로고
    • Antimicrobial peptides are expressed and produced in healthy and inflamed human synovial membranes
    • Paulsen F, Pufe T, Conradi L, Varoga D, Tsokos M, Papendieck J, et al. Antimicrobial peptides are expressed and produced in healthy and inflamed human synovial membranes. J Pathol 2002;198:369-377.
    • (2002) J Pathol , vol.198 , pp. 369-377
    • Paulsen, F.1    Pufe, T.2    Conradi, L.3    Varoga, D.4    Tsokos, M.5    Papendieck, J.6
  • 12
    • 20744447499 scopus 로고    scopus 로고
    • Human β-defensin-3 mediates tissue remodelling processes in articular cartilage by increasing metalloproteinases and reducing their endogenous inhibitors
    • Varoga D, Pufe T, Harder J, Schröder JM, Meyer-Hoffert U, Mentlein R, et al. Human β-defensin-3 mediates tissue remodelling processes in articular cartilage by increasing metalloproteinases and reducing their endogenous inhibitors. Arthritis Rheum 2005;52:1736-1745.
    • (2005) Arthritis Rheum , vol.52 , pp. 1736-1745
    • Varoga, D.1    Pufe, T.2    Harder, J.3    Schröder, J.M.4    Meyer-Hoffert, U.5    Mentlein, R.6
  • 13
    • 0015046195 scopus 로고
    • Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic hips. Correlation of morphology with biochemical and metabolic data
    • Mankin HJ, Dorfmaan H, Lipiello L, Zarins A. Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic hips. Correlation of morphology with biochemical and metabolic data. J Bone Jt Surg 1971;53A:523-537.
    • (1971) J Bone Jt Surg , vol.53 A , pp. 523-537
    • Mankin, H.J.1    Dorfmaan, H.2    Lipiello, L.3    Zarins, A.4
  • 15
    • 0034064619 scopus 로고    scopus 로고
    • Integrin expression by primary and immortalized human chondrocytes: Evidence of a differential role for α1β1 and α2β1 integrins mediating chondrocyte adhesion to types II and VI collagen
    • Loeser R, Sadiev S, Tan L, Goldring MB. Integrin expression by primary and immortalized human chondrocytes: evidence of a differential role for α1β1 and α2β1 integrins mediating chondrocyte adhesion to types II and VI collagen. Osteoarthritis Cartilage 2000; 8:96-105.
    • (2000) Osteoarthritis Cartilage , vol.8 , pp. 96-105
    • Loeser, R.1    Sadiev, S.2    Tan, L.3    Goldring, M.B.4
  • 16
    • 0037269828 scopus 로고    scopus 로고
    • The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon-γ-mediated inhibition in human chondrocytes: Requirement for Stat1α, Jak1, and Jak2
    • Osaki M, Tan L, Choy BK, Yoshida Y, Auron PE, Cheah KSE, et al. The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon-γ-mediated inhibition in human chondrocytes: requirement for Stat1α, Jak1, and Jak2. Biochem J 2003;369:103-115.
    • (2003) Biochem J , vol.369 , pp. 103-115
    • Osaki, M.1    Tan, L.2    Choy, B.K.3    Yoshida, Y.4    Auron, P.E.5    Cheah, K.S.E.6
  • 17
    • 12244276347 scopus 로고    scopus 로고
    • Endoglin is expressed on human chondrocytes and forms a heteromeric complex with betaglycan in a ligand and type II TGF-β receptor independent manner
    • Parker WL, Goldring MB, Philip A. Endoglin is expressed on human chondrocytes and forms a heteromeric complex with betaglycan in a ligand and type II TGF-β receptor independent manner. J Bone Miner Res 2003;18:289-302.
    • (2003) J Bone Miner Res , vol.18 , pp. 289-302
    • Parker, W.L.1    Goldring, M.B.2    Philip, A.3
  • 18
    • 0038381435 scopus 로고    scopus 로고
    • Egr-1 mediates transcriptional repression of COL2A1 promoter activity by interleukin-1β
    • Tan L, Peng H, Osaki M, Choy BK, Auron PE, Sandell LJ, et al. Egr-1 mediates transcriptional repression of COL2A1 promoter activity by interleukin-1β. J Biol Chem 2003;278:17 688-17 700.
    • (2003) J Biol Chem , vol.278 , pp. 17688-17700
    • Tan, L.1    Peng, H.2    Osaki, M.3    Choy, B.K.4    Auron, P.E.5    Sandell, L.J.6
  • 19
    • 0035460852 scopus 로고    scopus 로고
    • Anticytokine therapy for osteoarthritis
    • Goldring MB. Anticytokine therapy for osteoarthritis. Expert Opin Biol Ther 2001;1:817-829.
    • (2001) Expert Opin Biol Ther , vol.1 , pp. 817-829
    • Goldring, M.B.1
  • 20
    • 0035100991 scopus 로고    scopus 로고
    • Anti-cytokine therapy in chronic destructive arthritis
    • Van den Berg WB. Anti-cytokine therapy in chronic destructive arthritis. Arthritis Res 2001;3:18-26.
    • (2001) Arthritis Res , vol.3 , pp. 18-26
    • Van den Berg, W.B.1
  • 21
    • 0030961873 scopus 로고    scopus 로고
    • In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy
    • Pelletier JP, Caron JP, Evans C, Robbins PD, Georgescu HI, Janovic D, et al. In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy. Arthritis Rheum 1997;40:1012-1019.
    • (1997) Arthritis Rheum , vol.40 , pp. 1012-1019
    • Pelletier, J.P.1    Caron, J.P.2    Evans, C.3    Robbins, P.D.4    Georgescu, H.I.5    Janovic, D.6
  • 22
    • 0035937107 scopus 로고    scopus 로고
    • Isolation and characterization of human β-defensin-3, a novel human inducible peptide antibiotic
    • Harder J, Bartels J, Christophers E, Schröder JM. Isolation and characterization of human β-defensin-3, a novel human inducible peptide antibiotic. J Biol Chem 2001;276:5707-5713.
    • (2001) J Biol Chem , vol.276 , pp. 5707-5713
    • Harder, J.1    Bartels, J.2    Christophers, E.3    Schröder, J.M.4
  • 23
    • 0032169557 scopus 로고    scopus 로고
    • Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung
    • Bals R, Wang X, Wu Z, Freeman T, Bafna V, Zasloff M, et al. Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung. J Clin Invest 1998;102:874-880.
    • (1998) J Clin Invest , vol.102 , pp. 874-880
    • Bals, R.1    Wang, X.2    Wu, Z.3    Freeman, T.4    Bafna, V.5    Zasloff, M.6
  • 24
    • 0034703072 scopus 로고    scopus 로고
    • CD-14-dependent lipopolysaccharide-induced beta-defensin-2 expression in human tracheobronchial epithelium
    • Becker MN, Diamond G, Verghese MW, Randell SH. CD-14-dependent lipopolysaccharide-induced beta-defensin-2 expression in human tracheobronchial epithelium. J Biol Chem 2000;275:29 731-29 736.
    • (2000) J Biol Chem , vol.275 , pp. 29731-29736
    • Becker, M.N.1    Diamond, G.2    Verghese, M.W.3    Randell, S.H.4
  • 26
    • 0032734313 scopus 로고    scopus 로고
    • Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium
    • O'Neil DA, Porter EM, Elewaut D, Anderson GM, Eckmann L, Ganz T, et al. Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium. J Immunol 1999;163:6718-6724.
    • (1999) J Immunol , vol.163 , pp. 6718-6724
    • O'Neil, D.A.1    Porter, E.M.2    Elewaut, D.3    Anderson, G.M.4    Eckmann, L.5    Ganz, T.6
  • 27
    • 0033043785 scopus 로고    scopus 로고
    • Mouse beta-defensin 3 is an inducible antimicrobial peptide expressed in the epithelia of multiple organs
    • Bals R, Wang X, Meegalla RL, Wattler S, Weiner DJ, Nehls MC, et al. Mouse beta-defensin 3 is an inducible antimicrobial peptide expressed in the epithelia of multiple organs. Infect Immun 1999;67:3542-3547.
    • (1999) Infect Immun , vol.67 , pp. 3542-3547
    • Bals, R.1    Wang, X.2    Meegalla, R.L.3    Wattler, S.4    Weiner, D.J.5    Nehls, M.C.6
  • 28
    • 0034946907 scopus 로고    scopus 로고
    • Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A streptococcus
    • Dorschner RA, Pestonjamasp VK, Tamakuwala S, Ohtake T, Rudisill J, Nizet V, et al. Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A streptococcus. J Invest Dermatol 2001;117:91-96.
    • (2001) J Invest Dermatol , vol.117 , pp. 91-96
    • Dorschner, R.A.1    Pestonjamasp, V.K.2    Tamakuwala, S.3    Ohtake, T.4    Rudisill, J.5    Nizet, V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.