Inhibition of peroxisome proliferator-activated receptor γ promotes tumorigenesis through activation of the β-catenin/T cell factor (TCF) pathway in the mouse intestine

Journal of Pharmacological Sciences

Volumn 108, Issue 4, 2008, Pages 535-544

  Fujisawa, Toshio ^a   Sugiyama, Michiko ^a   Tomimoto, Ayako ^a   Wada, Koichiro ^b   Endo, Hiroki ^a   Takahashi, Hirokazu ^a   Yoneda, Kyoko ^a   Yoneda, Masato ^a   Inamori, Masahiko ^a   Saito, Satoru ^a   Terauchi, Yasuo ^a   Kadowaki, Takashi ^c   Tsuchiya, Naoto ^d   Nakagama, Hitoshi ^d   Nakajima, Atsushi ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

Aberrant crypt foci (ACF); Intestinal tumor; Peroxisome proliferator activated receptor (PPAR ); T0070907; catenin

Indexed keywords

2 CHLORO 5 NITRO N (4 PYRIDYL)BENZAMIDE; BETA CATENIN; CYCLIN D1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA ANTAGONIST; T CELL FACTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER MODEL; CARCINOGENESIS; CELL PROLIFERATION; COLON CANCER; COLON POLYP; CONTROLLED STUDY; EPITHELIUM CELL; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTESTINE CRYPT; MALE; MOUSE; NONHUMAN; ONCOGENE C MYC; SIGNAL TRANSDUCTION; SMALL INTESTINE;

EID: 58149174246     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.08193FP     Document Type: Article

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