메뉴 건너뛰기




Volumn 112, Issue 10, 2008, Pages 4069-4079

Amolecular signaling model of platelet phosphoinositide and calcium regulation during homeostasis and P2Y1 activation

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; CALCIUM; DIACYLGLYCEROL; GUANOSINE TRIPHOSPHATE; INOSITOL 1,4,5 TRISPHOSPHATE; PHOSPHATIDIC ACID; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; POLYPHOSPHOINOSITIDE; PURINERGIC P2Y1 RECEPTOR; PURINERGIC P2 RECEPTOR;

EID: 58149156729     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-05-157883     Document Type: Article
Times cited : (71)

References (50)
  • 1
    • 84884808691 scopus 로고    scopus 로고
    • Signal transduction during platelet plug formation
    • Michelson AD, ed, 2nd ed. Amsterdam: Elsevier Science;
    • Brass LF, Stalker TJ, Zhu L, Woulfe DS. Signal transduction during platelet plug formation. In: Michelson AD, ed. Platelets, 2nd ed. Amsterdam: Elsevier Science; 2007:319-346.
    • (2007) Platelets , pp. 319-346
    • Brass, L.F.1    Stalker, T.J.2    Zhu, L.3    Woulfe, D.S.4
  • 2
    • 0024532116 scopus 로고
    • Molecular mechanisms of platelet activation
    • Siess W. Molecular mechanisms of platelet activation. Physiol Rev. 1989;69:58-178.
    • (1989) Physiol Rev , vol.69 , pp. 58-178
    • Siess, W.1
  • 4
    • 8644224902 scopus 로고    scopus 로고
    • Computational modeling reveals how interplay between components of a GTPase-cycle module regulates signal transduction
    • Bornheimer SJ, Maurya MR, Farquhar MG, Subramaniam S. Computational modeling reveals how interplay between components of a GTPase-cycle module regulates signal transduction. Proc Natl Acad Sci U S A. 2004;101:15899- 15904.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 15899-15904
    • Bornheimer, S.J.1    Maurya, M.R.2    Farquhar, M.G.3    Subramaniam, S.4
  • 5
    • 0033570090 scopus 로고    scopus 로고
    • Quantification of short term signaling by the epidermal growth factor receptor
    • Kholodenko BN, Demin OV, Moehren G, Hoek JB. Quantification of short term signaling by the epidermal growth factor receptor. J Biol Chem. 1999;274:30169-30181.
    • (1999) J Biol Chem , vol.274 , pp. 30169-30181
    • Kholodenko, B.N.1    Demin, O.V.2    Moehren, G.3    Hoek, J.B.4
  • 6
    • 0037166290 scopus 로고    scopus 로고
    • A model for the stoichiometric regulation of blood coagulation
    • Hockin MF, Jones KC, Everse SJ, Mann KG. A model for the stoichiometric regulation of blood coagulation. J Biol Chem. 2002;277:18322- 18333.
    • (2002) J Biol Chem , vol.277 , pp. 18322-18333
    • Hockin, M.F.1    Jones, K.C.2    Everse, S.J.3    Mann, K.G.4
  • 7
    • 0035119193 scopus 로고    scopus 로고
    • Surface-mediated control of blood coagulation: The role of binding site densities and platelet deposition
    • Kuharsky AL, Fogelson AL. Surface-mediated control of blood coagulation: the role of binding site densities and platelet deposition. Biophys J. 2001;80:1050-1074.
    • (2001) Biophys J , vol.80 , pp. 1050-1074
    • Kuharsky, A.L.1    Fogelson, A.L.2
  • 8
    • 34547577428 scopus 로고    scopus 로고
    • Computationally derived points of fragility of a human cascade are consistent with current therapeutic strategies
    • Luan D, Zai M, Varner JD. Computationally derived points of fragility of a human cascade are consistent with current therapeutic strategies. PLoS Comput Biol. 2007;3:e142.
    • (2007) PLoS Comput Biol , vol.3
    • Luan, D.1    Zai, M.2    Varner, J.D.3
  • 9
    • 17644427718 scopus 로고    scopus 로고
    • Causal protein-signaling networks derived from multiparameter single-cell data
    • Sachs K, Perez O, Pe'er D, Lauffenburger DA, Nolan GP. Causal protein-signaling networks derived from multiparameter single-cell data. Science. 2005;308:523-529.
    • (2005) Science , vol.308 , pp. 523-529
    • Sachs, K.1    Perez, O.2    Pe'er, D.3    Lauffenburger, D.A.4    Nolan, G.P.5
  • 10
    • 33750351769 scopus 로고    scopus 로고
    • Data-driven modelling of signal-transduction networks
    • Janes KA, Yaffe MB. Data-driven modelling of signal-transduction networks. Nat Rev Mol Cell Biol. 2006;7:820-828.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 820-828
    • Janes, K.A.1    Yaffe, M.B.2
  • 11
    • 38949096839 scopus 로고    scopus 로고
    • Congenital disorders associated with platelet dysfunctions
    • Nurden P, Nurden AT. Congenital disorders associated with platelet dysfunctions. Thromb Haemost. 2008;99:253-263.
    • (2008) Thromb Haemost , vol.99 , pp. 253-263
    • Nurden, P.1    Nurden, A.T.2
  • 12
    • 34147162377 scopus 로고    scopus 로고
    • A guide to murine platelet structure, function, assays, and genetic alterations
    • Jirouskova M, Shet AS, Johnson GJ. A guide to murine platelet structure, function, assays, and genetic alterations. J Thromb Haemost. 2007;5: 661-669.
    • (2007) J Thromb Haemost , vol.5 , pp. 661-669
    • Jirouskova, M.1    Shet, A.S.2    Johnson, G.J.3
  • 13
    • 34247176342 scopus 로고    scopus 로고
    • In vivo thrombus formation in murine models
    • Sachs UJ, Nieswandt B. In vivo thrombus formation in murine models. Circ Res. 2007;100:979- 991.
    • (2007) Circ Res , vol.100 , pp. 979-991
    • Sachs, U.J.1    Nieswandt, B.2
  • 14
    • 59049106412 scopus 로고    scopus 로고
    • A brief history of ideas about platelets in health and disease
    • Michelson AD, ed, 2nd ed. Amsterdam: Elsevier Science;
    • Coller BS. A brief history of ideas about platelets in health and disease. In: Michelson AD, ed. Platelets, 2nd ed. Amsterdam: Elsevier Science; 2007:xxiii-xlii.
    • (2007) Platelets
    • Coller, B.S.1
  • 16
    • 0026643005 scopus 로고
    • Rapid ultrastructural changes in the dense tubular system following platelet activation
    • Ebbeling L, Robertson C, McNicol A, Gerrard JM. Rapid ultrastructural changes in the dense tubular system following platelet activation. Blood. 1992;80:718-723.
    • (1992) Blood , vol.80 , pp. 718-723
    • Ebbeling, L.1    Robertson, C.2    McNicol, A.3    Gerrard, J.M.4
  • 18
    • 0035884353 scopus 로고    scopus 로고
    • Ragged spiking of free calcium in ADPstimulated human platelets: Regulation of puff-like calcium signals in vitro and ex vivo
    • Heemskerk JW, Willems GM, Rook MB, Sage SO. Ragged spiking of free calcium in ADPstimulated human platelets: regulation of puff-like calcium signals in vitro and ex vivo. J Physiol. 2001;535:625-635.
    • (2001) J Physiol , vol.535 , pp. 625-635
    • Heemskerk, J.W.1    Willems, G.M.2    Rook, M.B.3    Sage, S.O.4
  • 19
    • 32544443964 scopus 로고    scopus 로고
    • Systems Biology Toolbox for MATLAB: A computational platform for research in systems biology
    • Schmidt H, Jirstrand M. Systems Biology Toolbox for MATLAB: a computational platform for research in systems biology. Bioinformatics. 2006; 22:514-515.
    • (2006) Bioinformatics , vol.22 , pp. 514-515
    • Schmidt, H.1    Jirstrand, M.2
  • 21
    • 1642498136 scopus 로고    scopus 로고
    • Agonist binding and Gqstimulating activities of the purified human P2Y1 receptor
    • Waldo GL, Harden TK. Agonist binding and Gqstimulating activities of the purified human P2Y1 receptor. Mol Pharmacol. 2004;65:426-436.
    • (2004) Mol Pharmacol , vol.65 , pp. 426-436
    • Waldo, G.L.1    Harden, T.K.2
  • 22
    • 0033828411 scopus 로고    scopus 로고
    • The roles of P(2X1)and P(2T AC)receptors in ADP-evoked calcium signalling in human platelets
    • Sage SO, Yamoah EH, Heemskerk JW. The roles of P(2X1)and P(2T AC)receptors in ADP-evoked calcium signalling in human platelets. Cell Calcium. 2000;28:119-126.
    • (2000) Cell Calcium , vol.28 , pp. 119-126
    • Sage, S.O.1    Yamoah, E.H.2    Heemskerk, J.W.3
  • 23
    • 27844508567 scopus 로고    scopus 로고
    • Two distinct Ca2+ compartments show differential sensitivity to thrombin, ADP and vasopressin in human platelets
    • Lopez JJ, Redondo PC, Salido GM, Pariente JA, Rosado JA. Two distinct Ca2+ compartments show differential sensitivity to thrombin, ADP and vasopressin in human platelets. Cell Signal. 2006;18:373-381.
    • (2006) Cell Signal , vol.18 , pp. 373-381
    • Lopez, J.J.1    Redondo, P.C.2    Salido, G.M.3    Pariente, J.A.4    Rosado, J.A.5
  • 24
    • 0037160144 scopus 로고    scopus 로고
    • Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 3 isoforms by steady-state and transient kinetic analyses
    • Dode L, Vilsen B, Van Baelen K, Wuytack F, Clausen JD, Andersen JP. Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 3 isoforms by steady-state and transient kinetic analyses. J Biol Chem. 2002;277:45579-45591.
    • (2002) J Biol Chem , vol.277 , pp. 45579-45591
    • Dode, L.1    Vilsen, B.2    Van Baelen, K.3    Wuytack, F.4    Clausen, J.D.5    Andersen, J.P.6
  • 25
    • 0037133251 scopus 로고    scopus 로고
    • A dynamic model of the type-2 inositol trisphosphate receptor
    • Sneyd J, Dufour JF. A dynamic model of the type-2 inositol trisphosphate receptor. Proc Natl Acad Sci U S A. 2002;99:2398-2403.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 2398-2403
    • Sneyd, J.1    Dufour, J.F.2
  • 26
    • 0023788853 scopus 로고
    • Calcium channels in thrombin-activated human platelet membrane
    • Zschauer A, van Breemen C, Buhler FR, Nelson MT. Calcium channels in thrombin-activated human platelet membrane. Nature. 1988;334:703- 705.
    • (1988) Nature , vol.334 , pp. 703-705
    • Zschauer, A.1    van Breemen, C.2    Buhler, F.R.3    Nelson, M.T.4
  • 27
    • 84884754706 scopus 로고    scopus 로고
    • Platelet structure
    • Michelson AD, ed, 2nd ed. Amsterdam: Elsevier Science;
    • White JG. Platelet structure. In: Michelson AD, ed. Platelets, 2nd ed. Amsterdam: Elsevier Science; 2007:45-73.
    • (2007) Platelets , pp. 45-73
    • White, J.G.1
  • 28
    • 0034664988 scopus 로고    scopus 로고
    • Biogenesis of endoplasmic reticulum proteins involved in Ca2+ signalling during megakaryocytic differentiation: An in vitro study
    • Lacabaratz-Porret C, Launay S, Corvazier E, Bredoux R, Papp B, Enouf J. Biogenesis of endoplasmic reticulum proteins involved in Ca2+ signalling during megakaryocytic differentiation: an in vitro study. Biochem J. 2000;350:723-734.
    • (2000) Biochem J , vol.350 , pp. 723-734
    • Lacabaratz-Porret, C.1    Launay, S.2    Corvazier, E.3    Bredoux, R.4    Papp, B.5    Enouf, J.6
  • 30
    • 0022340109 scopus 로고
    • A role for inositol triphosphate in intracellular Ca2+ mobilization and granule secretion in platelets
    • Brass LF, Joseph SK. A role for inositol triphosphate in intracellular Ca2+ mobilization and granule secretion in platelets. J Biol Chem. 1985;260: 15172-15179.
    • (1985) J Biol Chem , vol.260 , pp. 15172-15179
    • Brass, L.F.1    Joseph, S.K.2
  • 31
    • 0023621276 scopus 로고    scopus 로고
    • Tarver AP, King WG, Rittenhouse SE. Inositol 1,4,5-trisphosphate and inositol 1,2-cyclic 4,5- trisphosphate are minor components of total mass of inositol trisphosphate in thrombin-stimulated platelets: rapid formation of inositol 1,3,4- trisphosphate. J Biol Chem. 1987;262:17268- 17271.
    • Tarver AP, King WG, Rittenhouse SE. Inositol 1,4,5-trisphosphate and inositol 1,2-cyclic 4,5- trisphosphate are minor components of total mass of inositol trisphosphate in thrombin-stimulated platelets: rapid formation of inositol 1,3,4- trisphosphate. J Biol Chem. 1987;262:17268- 17271.
  • 32
    • 0021964583 scopus 로고
    • Phosphoinositide interconversion in thrombin-stimulated human platelets
    • Wilson DB, Neufeld EJ, Majerus PW. Phosphoinositide interconversion in thrombin-stimulated human platelets. J Biol Chem. 1985;260:1046- 1051.
    • (1985) J Biol Chem , vol.260 , pp. 1046-1051
    • Wilson, D.B.1    Neufeld, E.J.2    Majerus, P.W.3
  • 33
    • 0022970190 scopus 로고
    • Quantitative measurement of sn-1,2- diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells
    • Preiss J, Loomis CR, Bishop WR, Stein R, Niedel JE, Bell RM. Quantitative measurement of sn-1,2- diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells. J Biol Chem. 1986;261:8597-8600.
    • (1986) J Biol Chem , vol.261 , pp. 8597-8600
    • Preiss, J.1    Loomis, C.R.2    Bishop, W.R.3    Stein, R.4    Niedel, J.E.5    Bell, R.M.6
  • 35
    • 38849144753 scopus 로고    scopus 로고
    • Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes
    • Wang Y, Litvinov RI, Chen X, et al. Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes. J Clin Invest. 2008; 118:812-819.
    • (2008) J Clin Invest , vol.118 , pp. 812-819
    • Wang, Y.1    Litvinov, R.I.2    Chen, X.3
  • 36
    • 0031914973 scopus 로고    scopus 로고
    • Molecular basis for ADP-induced platelet activation: I. Evidence for three distinct ADP receptors on human platelets
    • Daniel JL, Dangelmaier C, Jin J, Ashby B, Smith JB, Kunapuli SP. Molecular basis for ADP-induced platelet activation: I. Evidence for three distinct ADP receptors on human platelets. J Biol Chem. 1998;273:2024-2029.
    • (1998) J Biol Chem , vol.273 , pp. 2024-2029
    • Daniel, J.L.1    Dangelmaier, C.2    Jin, J.3    Ashby, B.4    Smith, J.B.5    Kunapuli, S.P.6
  • 37
    • 0033104670 scopus 로고    scopus 로고
    • Phosphorylation by protein kinase C decreases catalytic activity of avian phospholipase C-beta
    • Filtz TM, Cunningham ML, Stanig KJ, Paterson A, Harden TK. Phosphorylation by protein kinase C decreases catalytic activity of avian phospholipase C-beta. Biochem J. 1999;338:257-264.
    • (1999) Biochem J , vol.338 , pp. 257-264
    • Filtz, T.M.1    Cunningham, M.L.2    Stanig, K.J.3    Paterson, A.4    Harden, T.K.5
  • 38
    • 0025027211 scopus 로고
    • Feedback regulation of phospholipase C-beta by protein kinase C
    • Ryu SH, Kim UH, Wahl MI, et al. Feedback regulation of phospholipase C-beta by protein kinase C. J Biol Chem. 1990;265:17941-17945.
    • (1990) J Biol Chem , vol.265 , pp. 17941-17945
    • Ryu, S.H.1    Kim, U.H.2    Wahl, M.I.3
  • 39
    • 0033555859 scopus 로고    scopus 로고
    • Emergent properties of networks of biological signaling pathways
    • Bhalla US, Iyengar R. Emergent properties of networks of biological signaling pathways. Science. 1999;283:381-387.
    • (1999) Science , vol.283 , pp. 381-387
    • Bhalla, U.S.1    Iyengar, R.2
  • 40
    • 14944348417 scopus 로고    scopus 로고
    • Differential regulation and relocalization of the platelet P2Y receptors after activation: A way to avoid loss of hemostatic properties?
    • Baurand A, Eckly A, Hechler B, et al. Differential regulation and relocalization of the platelet P2Y receptors after activation: a way to avoid loss of hemostatic properties? Mol Pharmacol. 2005;67: 721-733.
    • (2005) Mol Pharmacol , vol.67 , pp. 721-733
    • Baurand, A.1    Eckly, A.2    Hechler, B.3
  • 41
    • 0022363852 scopus 로고
    • Isolation of a phosphomonoesterase from human platelets that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate
    • Connolly TM, Bross TE, Majerus PW. Isolation of a phosphomonoesterase from human platelets that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate. J Biol Chem. 1985; 260:7868-7874.
    • (1985) J Biol Chem , vol.260 , pp. 7868-7874
    • Connolly, T.M.1    Bross, T.E.2    Majerus, P.W.3
  • 42
    • 0035793347 scopus 로고    scopus 로고
    • Inhibition of platelet function by administration of MRS2179, a P2Y1 receptor antagonist
    • Baurand A, Raboisson P, Freund M, et al. Inhibition of platelet function by administration of MRS2179, a P2Y1 receptor antagonist. Eur J Pharmacol. 2001;412:213-221.
    • (2001) Eur J Pharmacol , vol.412 , pp. 213-221
    • Baurand, A.1    Raboisson, P.2    Freund, M.3
  • 43
    • 0033578385 scopus 로고    scopus 로고
    • Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins
    • Mukhopadhyay S, Ross EM. Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins. Proc Natl Acad Sci U S A. 1999;96:9539-9544.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 9539-9544
    • Mukhopadhyay, S.1    Ross, E.M.2
  • 44
    • 0019381296 scopus 로고
    • Platelet aggregation induced by ADP from unsheared erythrocytes at physiological Ca++-concentration
    • Aursnes I, Gjesdal K, Abildgaard U. Platelet aggregation induced by ADP from unsheared erythrocytes at physiological Ca++-concentration. Br J Haematol. 1981;47:149-152.
    • (1981) Br J Haematol , vol.47 , pp. 149-152
    • Aursnes, I.1    Gjesdal, K.2    Abildgaard, U.3
  • 45
    • 0022343675 scopus 로고
    • Mass changes in myoinositol trisphosphate in human platelets stimulated by thrombin: Inhibitory effects of phorbol ester
    • Rittenhouse SE, Sasson JP. Mass changes in myoinositol trisphosphate in human platelets stimulated by thrombin: inhibitory effects of phorbol ester. J Biol Chem. 1985;260:8657-8660.
    • (1985) J Biol Chem , vol.260 , pp. 8657-8660
    • Rittenhouse, S.E.1    Sasson, J.P.2
  • 46
    • 33846503153 scopus 로고    scopus 로고
    • Both ligandand cell-specific parameters control ligand agonism in a kinetic model of g protein-coupled receptor signaling
    • Kinzer-Ursem TL, Linderman JJ. Both ligandand cell-specific parameters control ligand agonism in a kinetic model of g protein-coupled receptor signaling. PLoS Comput Biol. 2007;3: e6.
    • (2007) PLoS Comput Biol , vol.3
    • Kinzer-Ursem, T.L.1    Linderman, J.J.2
  • 47
    • 0026606856 scopus 로고
    • Spiking in cytosolic calcium concentration in single fibrinogen-bound fura-2-loaded human platelets
    • Heemskerk JW, Hoyland J, Mason WT, Sage SO. Spiking in cytosolic calcium concentration in single fibrinogen-bound fura-2-loaded human platelets. Biochem J. 1992;283:379-383.
    • (1992) Biochem J , vol.283 , pp. 379-383
    • Heemskerk, J.W.1    Hoyland, J.2    Mason, W.T.3    Sage, S.O.4
  • 48
    • 61849131149 scopus 로고
    • Exact stochastic simulation of coupled chemical-reactions
    • Gillespie DT. Exact stochastic simulation of coupled chemical-reactions. Abstr Am Chem Soc. 1977;173:128.
    • (1977) Abstr Am Chem Soc , vol.173 , pp. 128
    • Gillespie, D.T.1
  • 49
    • 0030612449 scopus 로고    scopus 로고
    • Ca2+]i oscillations and [Ca2+]i waves in rat megakaryocytes
    • Tertyshnikova S, Fein A. [Ca2+]i oscillations and [Ca2+]i waves in rat megakaryocytes. Cell Calcium. 1997;21:331-344.
    • (1997) Cell Calcium , vol.21 , pp. 331-344
    • Tertyshnikova, S.1    Fein, A.2
  • 50
    • 84884795579 scopus 로고    scopus 로고
    • Megakaryocyte development and platelet formation
    • Michelson AD, ed, 2nd ed. Amsterdam: Elsevier Science;
    • Italiano JEH. Megakaryocyte development and platelet formation. In: Michelson AD, ed. Platelets, 2nd ed. Amsterdam: Elsevier Science; 2007: 23-44.
    • (2007) Platelets , pp. 23-44
    • Italiano, J.E.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.