The influence of smoking on bone loss and response to nasal estradiol

Climacteric

Volumn 12, Issue 1, 2009, Pages 59-65

  Bjarnason, N H ^a,b   Nielsen, T F ^a   Jorgensen H L ^c   Christiansen, C ^d  

^a CENTER FOR CLINICAL AND BASIC RESEARCH   (Denmark)

^b DANISH MEDICINES AGENCY   (Denmark)

^c BISPEBJERG HOSPITAL   (Denmark)

^d NORDIC BIOSCIENCE A S   (Denmark)

Author keywords

Bone mass; Bone turnover; Estrogen; Nasal; Smoking; Thinness

Indexed keywords

ESTRADIOL; OSTEOCALCIN; PLACEBO; PROGESTERONE;

ADULT; ARTICLE; BONE DENSITY; BONE MASS; BONE TURNOVER; CIGARETTE SMOKING; CONTROLLED STUDY; DRUG EFFICACY; EXPLORATORY RESEARCH; FEMALE; HUMAN; LUMBAR SPINE; OSTEOLYSIS; POSTMENOPAUSE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

ADMINISTRATION, INTRANASAL; ADULT; AGED; BODY MASS INDEX; BONE DENSITY; BONE RESORPTION; DOUBLE-BLIND METHOD; ESTRADIOL; FEMALE; FOLLICLE STIMULATING HORMONE; HUMANS; LUMBAR VERTEBRAE; MIDDLE AGED; OSTEOPOROSIS, POSTMENOPAUSAL; PLACEBOS; PROGESTERONE; SMOKING;

EID: 58149142657     PISSN: 13697137     EISSN: 14730804     Source Type: Journal    
DOI: 10.1080/13697130802587689     Document Type: Article

References (31)

1. Notelovitz M, Lenihan JP, McDermott M, Kerber IJ, Nanavati N, Arce J. Initial 17beta-estradiol dose for treating vasomotor symptoms. Obstet Gynecol 2000;95:726-31
2. Manson JE, Hsia J, Johnson KC, et al. Women's Health Initiative Investigators. Estrogen plus progestin and the risk of coronary heart disease. N Engl J Med 2003;349:523-34
3. Cauley JA, Robbins J, Chen Z, et al. Women's Health Initiative Investigators. Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women's Health Initiative randomized trial. JAMA 2003;290:1729-38
4. Mokdad AH, Marks JS, Stroup DF, Gerberding JL. Actual causes of death in the United States, 2000. JAMA 2004;291:1238-45
5. Tankó LB, Christiansen C. An update on the antiestrogenic effect of smoking: a literature review with implications for researchers and practitioners. Menopause 2004;11:104-9
6. Szulc P, Garnero P, Claustrat B, Marchand F, Duboeuf F, Delmas PD. Increased bone resorption in moderate smokers with low body weight: The MINOS study. J Clin Endocrinol Metab 2002;87:666-74
7. Ward KD, Klesges RC. A meta-analysis of the effects of cigarette smoking on bone mineral density. Calcif Tissue Int 2001;68:259-70
8. Cassidenti DL, Vijod AG, Vijod MA, Stanczyk FZ, Lobo RA. Short-term effects of smoking on the pharmacokinetic profiles of micronized estradiol in postmenopausal women. Am J Obstet Gynecol 1990;163:1953-60
9. Jensen J, Christiansen C, Rodbro P. Cigarette smoking, serum estrogens, and bone loss during hormone-replacement therapy early after menopause. N Engl J Med 1985;313:973-5
10. Bjarnason NH, Christiansen C. The influence of thinness and smoking on bone loss and response to hormone replacement therapy in early postmenopausal women. J Clin Endocrinol Metab 2000;85:590-6
11. Bjarnason NH, Jørgensen C, Kremmer H, Alexandersen P, Christiansen C. Smoking reduces breast tenderness during oral hormone replacement therapy. Climacteric 2004;7:390-6
12. Bjarnason NH, Jørgensen HL, Byrjalsen I, Alexandersen P, Christiansen C. The influence of smoking on uterine bleeding during continuous and interrupted oral hormone therapy. Climacteric 2007;10:480-90
13. Bjarnason NH, Byrjalsen I, Jørgensen HL, Christiansen C. The influence of smoking on uterine bleeding during sequential oral hormone therapy. Climacteric 2007;10:147-54
14. Geisler J, Omsjø H, Helle SI, Ekse D, Silsand T, Lønning PE. Plasma oestrogen fractions in postmenopausal women receiving hormone replacement therapy: influence of route of administration and cigarette smoking. J Endocrinol 1999;162:265-70
15. Mattsson LA, Christiansen C, Colau JC, et al. Clinical equivalence of intranasal and oral 17beta-estradiol for postmenopausal symptoms. Am J Obstet Gynecol 2000;182:545-52
16. Devissaguet JP, Brion N, L'Hote O, Deloffre P. Pulsed estrogen therapy: pharmacokinetics of intranasal 17-beta-estradiol (S21400) in postmenopausal women and comparison with oral and transdermal formulations. Eur J Drug Metab Pharmacokinet 1999;24:265-71
17. Nielsen TF, Ravn P, Bagger YZ, Warming L, Christiansen C. Pulsed estrogen therapy in prevention of postmenopausal osteoporosis. A 2-year randomized, double blind, placebo-controlled study. Osteoporosis Int 2004;15:168-74
18. Rosenquist C, Qvist P, Bjarnason NH, Christiansen C. Measurement of a more stable region of osteocalcin in human serum using two monoclonal antibodies in an enzyme-linked immunosorbent assay (ELISA). Clin Chem 1995;41:1439-45
19. Bonde M, Qvist P, Fledelius C, Riis BJ, Christiansen C. Applications of an enzyme immunoassay for a new marker of bone resorption (CrossLaps): follow-up on hormone replacement therapy and osteoporosis risk assessment. J Clin Endocrinol Metab 1995;80:864-8
20. Bjarnason NH, Byrjalsen I, Hassager C, Haarbo J, Christiansen C. Low dose estradiol in combination with gestodene to prevent early postmenopausal bone loss. Am J Obstet Gynecol 2000;183:550-60
21. Bjarnason NH, Alexandersen P, Christiansen C. Number of years since menopause: Spontaneous bone loss is dependent, but response to HRT is independent. Bone 2002;30:637-42
22. Michnovicz JJ, Hershcopf RJ, Naganuma H, Bradlow HL, Fishman J. Increased 2-hydroxylation of estradiol as a possible mechanism for the anti-estrogenic effect of cigarette smoking. N Engl J Med 1986;3151:1305-9
23. Yamazaki H, Shaw PM, Guengerich FP, Shimada T. Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes. Chem Res Toxicol 1998;11:659-65
24. Ding X, Kaminsky LS. Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts. Annu Rev Pharmacol Toxicol 2003;43:149-73
25. Zhang J, Zhang Q-Y, Guo J, Zhou Y, Ding Z. Identification and functional characterization of a conserved nuclear factor 1-like element in the proximal promotor region of CYP1A2 gene specifically expressed in the liver and olfactory mucosa. J Biol Chem 2000;275:8895-902
26. Wardlaw SA, Nikula KJ, Kracko DA, Finch GL, Thornton-Manning JR, Dahl AR. Effect of cigarette smoke on CYP1A1, CYP1A2 and CYP2B1/2 of nasal mucosa in F344 rats. Carcinogenesis 1998;19:655-62
27. Jensen J, Christiansen C. Effects of smoking on serum lipoproteins and bone mineral content during postmenopausal hormone replacement. Am J Obstet Gynecol 1988;159:820-5
28. Bjarnason NH. Drug metabolism and variability. N Engl J Med 2005;353:955-6
29. Komulainen M, Kroger H, Tuppurainen MT, Heikkinen AM, Honkanen R, Saarikoski S. Identification of early postmenopausal women with no bone response to HRT: results of a five-year clinical trial. Osteoporos Int 2000;11:211-18
30. Ravn P, Cizza G, Bjarnason NH, et al. for the early postmenopausal intervention cohort (EPIC) study group. Low body mass index is an important risk factor for low bone mass and increased bone loss in early postmenopausal women. J Bone Miner Res 1999;14:1622-7
31. The Writing Group for the PEPI. Effects of hormone therapy on bone mineral density: results from the postmenopausal estrogen/ progestin interventions (PEPI) trial. JAMA 1996;276:1389-96