Tubular epithelial cells have the capacity to transdifferentiate into CD68-positive macrophage-like cells by oxidative stress

Inflammation Research

Volumn 57, Issue 12, 2008, Pages 593-600

  Tanaka, M ^a,b   Suzuki, Y ^a   Shirato, I ^a   Takahara, H ^a   Shibata, T ^a   Sugaya, T ^a   Shimamoto, K ^b   Horikoshi, S ^a   Tomino, Y ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

CD68 positive macrophage like cells; Free fatty acid; Oxdative stress; Transdifferentiation; Tubular epithelial cells

Indexed keywords

3 NITROTYROSINE; CD63 ANTIGEN; CD68 ANTIGEN; CYTOKERATIN AE1; CYTOKERATIN AE3; RAC1 PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL TRANSDIFFERENTIATION; IMMUNOHISTOCHEMISTRY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MACROPHAGE; MALE; NEPHROSIS; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; EPITHELIAL CELLS; KERATINS; KIDNEY TUBULES, PROXIMAL; LIPID METABOLISM; MACROPHAGES; MALE; MICE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CELL SURFACE; URINE;

EID: 58149139076     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-008-7171-1     Document Type: Article

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