Analysis of structure and function of the giant protein Pf332 in Plasmodium falciparum

Molecular Microbiology

Volumn 71, Issue 1, 2009, Pages 48-65

  Hodder, Anthony N ^a   Maier, Alexander G ^a   Rug, Melanie ^a   Brown, Monica ^a   Hommel, Mirja ^a   Pantic, Ivan ^b   Puig De Morales Marinkovic, Marina ^b   Smith, Brian ^a   Triglia, Tony ^a   Beeson, James ^a   Cowman, Alan F ^a  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CELL PROTEIN; PROTEIN PF 332; PROTEIN PK ALPHA DBL; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CELL CULTURE; CELL INVASION; DISULFIDE BOND; ERYTHROCYTE; IN VITRO STUDY; OXIDATION; PARASITOSIS; PLASMODIUM FALCIPARUM; PLASMODIUM KNOWLESI; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; BINDING SITES; ERYTHROCYTES; GENE DELETION; HUMANS; MEROZOITES; MODELS, MOLECULAR; PEPTIDE MAPPING; PLASMODIUM FALCIPARUM; PROTEIN FOLDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

PLASMODIUM FALCIPARUM; PLASMODIUM KNOWLESI;

EID: 58149133825     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2008.06508.x     Document Type: Article

References (51)

1. Adams, J.H., Blair, P.L., Kaneko, O. Peterson, D.S. (2001) An expanding ebl family of Plasmodium falciparum. Trends Parasitol 17 : 297 299.
2. Ahlborg, N., Iqbal, J., Hansson, M., Uhlen, M., Mattei, D., Perlmann, P., et al. (1995) Immunogens containing sequences from antigen Pf332 induce Plasmodium falciparum-reactive antibodies which inhibit parasite growth but not cytoadherence. Parasite Immunol 17 : 341 352.
3. Ahlborg, N., Iqbal, J., Bjork, L., Stahl, S., Perlmann, P. Berzins, K. (1996) Plasmodium falciparum: differential parasite growth inhibition mediated by antibodies to the antigens Pf332 and Pf155/RESA. Exp Parasitol 82 : 155 163.
4. Aley, S.B., Sherwood, J.A., Marsh, K., Eidelman, O. Howard, R.J. (1986) Identification of isolate-specific proteins on sorbitol-enriched Plasmodium falciparum infected erythrocytes from Gambian patients. Parasitology 92 : 511 525.
5. Baruch, D.I., Pasloske, B.L., Singh, H.B., Bi, X., Ma, X.C., Feldman, M., et al. (1995) Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes. Cell 82 : 77 87.
6. Baum, J., Thomas, A.W. Conway, D.J. (2003) Evidence for diversifying selection on erythrocyte-binding antigens of Plasmodium falciparum and P. vivax. Genetics 163 : 1327 1336.
7. Beeson, J.G., Mann, E.J., Elliott, S.R., Lema, V.M., Tadesse, E., Molyneux, M.E., et al. (2004) Antibodies to variant surface antigens of Plasmodium falciparum-infected erythrocytes and adhesion inhibitory antibodies are associated with placental malaria and have overlapping and distinct targets. J Infect Dis 189 : 540 551.
8. Beeson, J.G., Mann, E.J., Byrne, T.J., Caragounis, A., Elliott, S.R., Brown, G.V. Rogerson, S.J. (2006) Antigenic differences and conservation among placental Plasmodium falciparum-infected erythrocytes and acquisition of variant-specific and cross-reactive antibodies. J Infect Dis 193 : 721 730.
9. Beeson, J.G., Ndungu, F., Persson, K.E., Chesson, J.M., Kelly, G.L., Uyoga, S., et al. (2007) Antibodies among men and children to placental-binding Plasmodium falciparum-infected erythrocytes that express var2csa. Am J Trop Med Hyg 77 : 22 28.
10. Berendsen, H.J., Postma, J.P.M., van Gunsteren, W.F., Dinola, A. Haak, J.R. (1984) Molecular dynamics with coupling to an external bath. J Chem Phys 81 : 3684 3690.
11. Blisnick, T., Morales Betoulle, M.E., Barale, J., Uzureau, P., Berry, L., Desroses, S., et al. (2000) Pfsbp1, a Maurer's cleft Plasmodium falciparum protein, is associated with the erythrocyte skeleton. Mol Biochem Parasitol 111 : 107 121.
12. Bozdech, Z., Llinas, M., Pulliam, B.L., Wong, E.D., Zhu, J. DeRisi, J.L. (2003) The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum. PLoS Biol 1 : E5.
13. Choe, H., Moore, M.J., Owens, C.M., Wright, P.L., Vasilieva, N., Li, W., et al. (2005) Sulphated tyrosines mediate association of chemokines and Plasmodium vivax Duffy binding protein with the Duffy antigen/receptor for chemokines (DARC). Mol Microbiol 55 : 1413 1422.
14. Cowman, A.F. Crabb, B.S. (2006) Invasion of red blood cells by malaria parasites. Cell 124 : 755 766.
15. Culvenor, J.G., Langford, C.J., Crewther, P.E., Saint, R.B., Coppel, R.L., Kemp, D.J., et al. (1987) Plasmodium falciparum: identification and localization of a knob protein antigen expressed by a cDNA clone. Exp Parasitol 63 : 58 67.
16. Duffy, M.F., Maier, A.G., Byrne, T.J., Marty, A.J., Elliott, S.R., O'Neill, T., et al. (2006) VAR2CSA is the principal ligand for chondroitin sulfate A in two allogeneic isolates of Plasmodium falciparum. Mol Biochem Parasitol 148 : 117 124.
17. Elliott, S.R., Duffy, M.F., Byrne, T.J., Beeson, J.G., Mann, E.J., Wilson, D.W., et al. (2005) Cross-reactive surface epitopes on chondroitin sulfate A-adherent Plasmodium falciparum-infected erythrocytes are associated with transcription of var2csa. Infect Immun 73 : 2848 2856.
18. Fabry, B., Maksym, G.N., Shore, S.A., Moore, P.E., Panettieri, R.A., Butler, J.P., Jr. Fredberg, J.J. (2001) Selected contribution: time course and heterogeneity of contractile responses in cultured human airway smooth muscle cells. J Appl Physiol 91 : 986 994.
19. Fabry, B., Maksym, G.N., Butler, J.P., Glogauer, M., Navajas, D., Taback, N.A., et al. (2003) Time scale and other invariants of integrative mechanical behavior in living cells. Phys Rev E Stat Nonlin Soft Matter Phys 68 : 041914.
20. Fiser, A. Sali, A. (2003) ModLoop: automated modeling of loops in protein structures. Bioinformatics 19 : 2500 2501.
21. Gardner, M.J.N., Hall, E., Fung, O., White, M., Berriman, R.W., Hyman, J.M., et al. (2002) Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 419 : 498 511.
22. Glenister, F.K., Fernandez, K.M., Kats, L.M., Hanssen, E., Mohandas, N., Coppel, R.L. Cooke, B.M. (2008) Functional alteration of red blood cells by a Mega-Dalton protein of Plasmodium falciparum. Blood. Epub ahead of print 2 October.
23. Hess, B., Bekker, H., Berendsen, H.J.C. Fraaije, J.G.E.M. (1997) LINCS: a linear constraint solver for molecular stimulations. J Comput Chem 18 : 1463 1472.
24. Hodder, A.N., Crewther, P.E., Matthew, M.L., Reid, G.E., Moritz, R.L., Simpson, R.J. Anders, R.F. (1996) The disulfide bond structure of Plasmodium apical membrane antigen-1. J Biol Chem 271 : 29446 29452.
25. Hodder, A.N., Crewther, P.E. Anders, R.F. (2001) Specificity of the protective antibody response to apical membrane antigen 1. Infect Immun 69 : 3286 3294.
26. Hodder, A.N., Drew, D.R., Epa, V.C., Delorenzi, M., Bourgon, R., Miller, S.K., et al. (2003) Enzymic, phylogenetic, and structural characterization of the unusual papain-like protease domain of Plasmodium falciparum SERA5. J Biol Chem 278 : 48169 48177.
27. Holder, A.A. Freeman, R.R. (1982) Biosynthesis and processing of a Plasmodium falciparum schizont antigen recognized by immune serum and a monoclonal antibody. J Exp Med 156 : 1528 1538.
28. Kilejian, A. (1979) Characterization of a protein correlated with the production of knob-like protrusions on membranes of erythrocytes infected with Plasmodium falciparum. Proc Natl Acad Sci USA 76 : 4650 4653.
29. Lambros, C. Vanderberg, J.P. (1979) Synchronization of Plasmodium falciparum erythrocytic stages in culture. J Parasitol 65 : 418 420.
30. Le Roch, K.G., Zhou, Y., Blair, P.L., Grainger, M., Moch, J.K., Haynes, J.D., et al. (2003) Discovery of gene function by expression profiling of the malaria parasite life cycle. Science 301 : 1503 1508.
31. Leech, J.H., Barnwell, J.W., Miller, L.H. Howard, R.J. (1984) Identification of a strain-specific malarial antigen exposed on the surface of Plasmodium falciparum-infected erythrocytes. J Exp Med 159 : 1567 1575.
32. Lindahl, M. (2001) Strul - a method for 3D alignment of single-particle projections based on common line correlation in Fourier space. Ultramicroscopy 87 : 165 175.
33. Lopez-Estrano, C., Bhattacharjee, S., Harrison, T. Haldar, K. (2003) Cooperative domains define a unique host cell-targeting signal in Plasmodium falciparum-infected erythrocytes. Proc Natl Acad Sci USA 100 : 12402 12407.
34. Maier, A.G., Braks, J.A., Waters, A.P. Cowman, A.F. (2006) Negative selection using yeast cytosine deaminase/uracil phosphoribosyl transferase in Plasmodium falciparum for targeted gene deletion by double crossover recombination. Mol Biochem Parasitology 150 : 118 121.
35. Maier, A.G., Rug, M., O'Neill, M.T., Brown, M., Chakravorty, S., Szestak, T., et al. (2008) Exported proteins required for virulence and rigidity of Plasmodium falciparum-infected human erythrocytes. Cell 134 : 48 61.
36. Marti, M., Baum, J., Rug, M., Tilley, L. Cowman, A.F. (2005) Signal-mediated export of proteins from the malaria parasite to the host erythrocyte. J Cell Biol 171 : 587 592.
37. Mattei, D. Scherf, A. (1992) The Pf332 gene of Plasmodium falciparum codes for a giant protein that is translocated from the parasite to the membrane of infected erythrocytes. Gene 110 : 71 79.
38. Mattei, D., Hinterberg, K. Scherf, A. (1992) Pf11-1 and Pf332: two giant proteins synthesized in erythrocytes infected with Plasmodium falciparum. Parasitol Today 8 : 426 428.
39. Miller, L.H., Baruch, D.I., Marsh, K. Doumbo, O.K. (2002) The pathogenic basis of malaria. Nature 415 : 673 679.
40. Moll, K., Chene, A., Ribacke, U., Kaneko, O., Nilsson, S., Winter, G., et al. (2007) A novel DBL-domain of the P. falciparum 332 molecule possibly involved in erythrocyte adhesion. PLoS ONE 2 : e477.
41. Puig-de-Morales-Marinkovic, M., Turner, K.T., Butler, J.P., Fredberg, J.J. Suresh, S. (2007) Viscoelasticity of the human red blood cell. Am J Physiol Cell Physiol 293 : C597 C605.
42. Rubio, J.P., Triglia, T., Kemp, D.J., de Bruin, D., Ravetch, J.V. Cowman, A.F. (1995) A YAC contig map of Plasmodium falciparum chromosome 4: characterization of a DNA amplification between two recently separated isolates. Genomics 26 : 192 198.
43. Rug, M., Wickham, M.E., Foley, M., Cowman, A.F. Tilley, L. (2004) Correct promoter control is needed for trafficking of the ring-infected erythrocyte surface antigen to the host cytosol in transfected malaria parasites. Infect Immun 72 : 6095 6105.
44. Singh, S.K., Hora, R., Belrhali, H., Chitnis, C.E. Sharma, A. (2006) Structural basis for Duffy recognition by the malaria parasite Duffy-binding-like domain. Nature 439 : 741 744.
45. Smith, J.D., Chitnis, C.E., Craig, A.G., Roberts, D.J., Hudson-Taylor, D.E., Peterson, D.S., et al. (1995) Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes. Cell 82 : 101 110.
46. Smith, R.H., Jr., Jorgensen, W.L., Tirado-Rives, J., Lamb, M.L., Janssen, P.A., Michejda, C.J. Kroeger Smith, M.B. (1998) Prediction of binding affinities for TIBO inhibitors of HIV-1 reverse transcriptase using Monte Carlo simulations in a linear response method. J Med Chem 41 : 5272 5286.
47. Snow, R.W., Guerra, C.A., Noor, A.M., Myint, H.Y. Hay, S.I. (2005) The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature 434 : 214 217.
48. Su, X.Z., Heatwole, V.M., Wertheimer, S.P., Guinet, F., Herrfeldt, J.A., Peterson, D.S., et al. (1995) The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of Plasmodium falciparum-infected erythrocytes. Cell 82 : 89 100.
49. Tolia, N.H., Enemark, E.J., Sim, B.K. Joshua-Tor, L. (2005) Structural basis for the EBA-175 erythrocyte invasion pathway of the malaria parasite Plasmodium falciparum. Cell 122 : 183 193.
50. Waterkeyn, J.F., Wickham, M.E., Davern, K., Cooke, B.M., Reeder, J.C., Culvenor, J.G., et al. (2000) Targeted mutagenesis of Plasmodium falciparum erythrocyte membrane protein 3 (PfEMP3) disrupts cytoadherence of malaria-infected red blood cells. EMBO J 19 : 2813 2823.
51. Wickham, M.E., Rug, M., Ralph, S.A., Klonis, N., McFadden, G.I., Tilley, L. Cowman, A.F. (2001) Trafficking and assembly of the cytoadherence complex in Plasmodium falciparum-infected human erythrocytes. EMBO J 20 : 1 14.