Mutations at human immunodeficiency virus type 1 reverse transcriptase tryptophan repeat motif attenuate the inhibitory effect of efavirenz on virus production

Virology

Volumn 383, Issue 2, 2009, Pages 261-270

  Chiang, Chien Cheng ^a,b   Wang, Shiu Mei ^a,b   Tseng, Ying Tzu ^a,b   Huang, Kuo Jung ^a,b   Wang, Chin Tien ^a,b  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Efavirenz; Gag processing; Gag Pol; HIV 1; NNRTI; RT dimerization; Tryptophan repeat motif

Indexed keywords

ALANINE; EFAVIRENZ; GAG PROTEIN; PROTEINASE; RNA DIRECTED DNA POLYMERASE; TRYPTOPHAN;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DIMERIZATION; DRUG INHIBITION; ENZYME ACTIVITY; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; VIRUS PARTICLE; VIRUS REPLICATION;

AMINO ACID MOTIFS; AMINO ACID SUBSTITUTION; ANTI-HIV AGENTS; BENZOXAZINES; CELL LINE; HIV REVERSE TRANSCRIPTASE; HIV-1; HUMANS; MUTATION, MISSENSE; VIRUS ASSEMBLY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 58149107293     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2008.10.027     Document Type: Article

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