Enforced expression of the transcriptional coactivator OBF1 impairs B cell differentiation at the earliest stage of development

PLoS ONE

Volumn 3, Issue 12, 2008, Pages

  Bordon, Alain ^a   Bosco, Nabil ^b   Du Roure, Camille ^a   Bartholdy, Boris ^a,c   Kohler, Hubertus ^a   Matthias, Gabriele ^a   Rolink, Antonius G ^b   Matthias, Patrick ^a  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR OBF1; UNCLASSIFIED DRUG; POU2AF1 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL MATURATION; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DOWN REGULATION; ENHANCER REGION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE OVEREXPRESSION; IMMUNE RESPONSE; LYMPHOCYTE COUNT; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; REGULATORY MECHANISM; TRANSCRIPTOMICS; TRANSGENIC MOUSE; TRANSLATION REGULATION; UPREGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; EMBRYO DEVELOPMENT; EXTRAMEDULLARY HEMATOPOIESIS; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; SPLEEN; TIME;

MUS; MUS MUSCULUS;

ANIMALS; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; EMBRYONIC DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEMATOPOIESIS, EXTRAMEDULLARY; LYMPHOCYTE COUNT; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; SPLEEN; TIME FACTORS; TRANS-ACTIVATORS; TRANSFECTION; UP-REGULATION;

EID: 58049196844     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004007     Document Type: Article

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