메뉴 건너뛰기




Volumn 320, Issue 1-2, 2009, Pages 149-162

Ameliorative effect of combination of benfotiamine and fenofibrate in diabetes-induced vascular endothelial dysfunction and nephropathy in the rat

Author keywords

Benfotiamine; Diabetes; Fenofibrate; Nephropathy; Oxidative stress; Vascular endothelial dysfunction

Indexed keywords

BENFOTIAMINE; CHOLESTEROL; CREATININE; FENOFIBRATE; LISINOPRIL; TRIACYLGLYCEROL; UREA;

EID: 58049134293     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-008-9917-z     Document Type: Article
Times cited : (72)

References (59)
  • 1
    • 0033533807 scopus 로고    scopus 로고
    • Nephropathy in patients with type 2 diabetes mellitus
    • doi: 10.1056/NEJM199910073411506
    • Ritz E, Orth SR (1999) Nephropathy in patients with type 2 diabetes mellitus. N Engl J Med 341:1127-1133. doi: 10.1056/NEJM199910073411506
    • (1999) N Engl J Med , vol.341 , pp. 1127-1133
    • Ritz, E.1    Orth, S.R.2
  • 2
    • 0033920419 scopus 로고    scopus 로고
    • Endothelial dysfunction in diabetes
    • doi: 10.1038/sj.bjp.0703393
    • De Vriese AS, Verbeuren TJ, De Voorde JV et al (2000) Endothelial dysfunction in diabetes. Br J Pharmacol 130:963-974. doi: 10.1038/ sj.bjp.0703393
    • (2000) Br J Pharmacol , vol.130 , pp. 963-974
    • De Vriese, A.S.1    Verbeuren, T.J.2    De Voorde, J.V.3
  • 3
    • 0035116150 scopus 로고    scopus 로고
    • Diabetes and endothelial dysfunction: A clinical perspective
    • doi: 10.1210/er.22.1.36
    • Escandon JC, Cipolla M (2001) Diabetes and endothelial dysfunction: A clinical perspective. Endocr Rev 22:36-52. doi: 10.1210/er.22.1.36
    • (2001) Endocr Rev , vol.22 , pp. 36-52
    • Escandon, J.C.1    Cipolla, M.2
  • 4
    • 44449158575 scopus 로고    scopus 로고
    • Pharmacological interventions to prevent vascular endothelial dysfunction: Future directions
    • doi: 10.1248/jhs.54.1
    • Balakumar P, Koladiya RU, Ramasamy S et al (2008) Pharmacological interventions to prevent vascular endothelial dysfunction: Future directions. J Health Sci 54:1-16. doi: 10.1248/jhs.54.1
    • (2008) J Health Sci , vol.54 , pp. 1-16
    • Balakumar, P.1    Koladiya, R.U.2    Ramasamy, S.3
  • 5
    • 0035960677 scopus 로고    scopus 로고
    • Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease
    • doi: 10.1161/hc4601.099485
    • Heitzer T, Schlinzig T, Krohn K et al (2001) Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation 104:2673-2703. doi: 10.1161/ hc4601.099485
    • (2001) Circulation , vol.104 , pp. 2673-2703
    • Heitzer, T.1    Schlinzig, T.2    Krohn, K.3
  • 6
    • 0034820972 scopus 로고    scopus 로고
    • Endothelium-dependent vasorelaxation is inhibited by in vivo depletion of vascular thiol levels: Role of endothelial nitric oxide synthase
    • doi: 10.1080/10715760100300901
    • Laursen JB, Boesgaard S, Trautner S et al (2001) Endothelium-dependent vasorelaxation is inhibited by in vivo depletion of vascular thiol levels: Role of endothelial nitric oxide synthase. Free Radic Res 35:387-394. doi: 10.1080/10715760100300901
    • (2001) Free Radic Res , vol.35 , pp. 387-394
    • Laursen, J.B.1    Boesgaard, S.2    Trautner, S.3
  • 7
    • 0037337890 scopus 로고    scopus 로고
    • Vitamins reverse endothelial dysfunction through regulation of eNOS and NADPH oxidase activities
    • doi: 10.1161/01.HYP.0000057421.28533.37
    • Ulker S, McKeown P, Bayraktutan U (2003) Vitamins reverse endothelial dysfunction through regulation of eNOS and NADPH oxidase activities. Hypertension 41:534-541. doi: 10.1161/01.HYP.0000057421.28533.37
    • (2003) Hypertension , vol.41 , pp. 534-541
    • Ulker, S.1    McKeown, P.2    Bayraktutan, U.3
  • 8
    • 39249083879 scopus 로고    scopus 로고
    • Potential target sites to modulate vascular endothelial dysfunction: Current perspectives and future directions
    • doi: 10.1016/j.tox.2007.12.011
    • Balakumar P, Kaur T, Singh M (2008) Potential target sites to modulate vascular endothelial dysfunction: Current perspectives and future directions. Toxicology 245:49-64. doi: 10.1016/j.tox.2007.12.011
    • (2008) Toxicology , vol.245 , pp. 49-64
    • Balakumar, P.1    Kaur, T.2    Singh, M.3
  • 9
    • 0035793616 scopus 로고    scopus 로고
    • Mechanisms underlying endothelial dysfunction in diabetes mellitus
    • Hink U, Li H, Mollnau H et al (2001) Mechanisms underlying endothelial dysfunction in diabetes mellitus. Circ Res 88:e14-e22
    • (2001) Circ Res , vol.88
    • Hink, U.1    Li, H.2    Mollnau, H.3
  • 10
    • 0036599334 scopus 로고    scopus 로고
    • Advanced glycation end products and endothelial dysfunction in type 2 diabetes
    • doi: 10.2337/diacare.25.6.1055
    • Kathryn CB, Chow WS, Victor HG et al (2002) Advanced glycation end products and endothelial dysfunction in type 2 diabetes. Diabetes Care 25:1055-1059. doi: 10.2337/diacare.25.6.1055
    • (2002) Diabetes Care , vol.25 , pp. 1055-1059
    • Kathryn, C.B.1    Chow, W.S.2    Victor, H.G.3
  • 11
    • 33644859602 scopus 로고    scopus 로고
    • Elevated markers of endothelial dysfunction predict type 2 diabetes mellitus in middle-aged men and women from the general population
    • doi: 10.1161/01.ATV.0000198392.05307.aa
    • Thorand B, Baumert J, Chambless L et al (2006) Elevated markers of endothelial dysfunction predict type 2 diabetes mellitus in middle-aged men and women from the general population. Arterioscler Thromb Vasc Biol 26:398-412. doi: 10.1161/01.ATV.0000198392.05307.aa
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 398-412
    • Thorand, B.1    Baumert, J.2    Chambless, L.3
  • 12
    • 33846701668 scopus 로고    scopus 로고
    • Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy
    • doi: 10.1681/ASN.2006050459
    • Nakagawa T, Sato W, Glushakova W et al (2007) Diabetic endothelial nitric oxide synthase knockout mice develop advanced diabetic nephropathy. J Am Soc Nephrol 18:539-550. doi: 10.1681/ASN.2006050459
    • (2007) J Am Soc Nephrol , vol.18 , pp. 539-550
    • Nakagawa, T.1    Sato, W.2    Glushakova, W.3
  • 13
    • 35848956112 scopus 로고    scopus 로고
    • Diabetic nephropathy is associated with oxidative stress and decreased renal nitric oxide production
    • doi: 10.1681/ASN.2006080895
    • Prabhakar S, Starnes J, Shi S et al (2007) Diabetic nephropathy is associated with oxidative stress and decreased renal nitric oxide production. J Am Soc Nephrol 18:2945-2952. doi: 10.1681/ASN.2006080895
    • (2007) J Am Soc Nephrol , vol.18 , pp. 2945-2952
    • Prabhakar, S.1    Starnes, J.2    Shi, S.3
  • 14
    • 42349104656 scopus 로고    scopus 로고
    • Endothelial dysfunction in hyperglycemia as a trigger of atherosclerosis
    • doi: 10.2174/1573399052952550
    • Nakagami H, Kaneda Y, Ogihara T et al (2005) Endothelial dysfunction in hyperglycemia as a trigger of atherosclerosis. Curr Diabetes Rev 1:59-63. doi: 10.2174/1573399052952550
    • (2005) Curr Diabetes Rev , vol.1 , pp. 59-63
    • Nakagami, H.1    Kaneda, Y.2    Ogihara, T.3
  • 15
    • 34347375693 scopus 로고    scopus 로고
    • Circulating levels of endothelial adhesion molecules and risk of diabetes in an ethnically diverse cohort of women
    • doi: 10.2337/db07-0250
    • Song Y, Maanson JE, Tinker L et al (2007) Circulating levels of endothelial adhesion molecules and risk of diabetes in an ethnically diverse cohort of women. Diabetes 56:1898-1904. doi: 10.2337/db07-0250
    • (2007) Diabetes , vol.56 , pp. 1898-1904
    • Song, Y.1    Maanson, J.E.2    Tinker, L.3
  • 16
    • 61349119943 scopus 로고    scopus 로고
    • Vascular endothelial dysfunction: A tug of war in diabetic nephropathy?
    • doi: 10.1016/j.biopha.2008.08.008
    • Balakumar P, Chakkarwar VA, Krishan P et al (2008) Vascular endothelial dysfunction: A tug of war in diabetic nephropathy? Biomed Pharmacother. doi: 10.1016/j.biopha.2008.08.008
    • (2008) Biomed Pharmacother
    • Balakumar, P.1    Chakkarwar, V.A.2    Krishan, P.3
  • 17
    • 0034993799 scopus 로고    scopus 로고
    • Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells
    • doi: 10.2337/diabetes.50.6.1472
    • Nakagami H, Morishita R, Yamamoto K et al (2001) Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells. Diabetes 50:1472-1481. doi: 10.2337/diabetes.50.6.1472
    • (2001) Diabetes , vol.50 , pp. 1472-1481
    • Nakagami, H.1    Morishita, R.2    Yamamoto, K.3
  • 18
    • 33749236623 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice
    • doi: 10.1681/ASN.2006070798
    • Zhao HJ, Wang S, Cheng H et al (2006) Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice. J Am Soc Nephrol 17:2664-2669. doi: 10.1681/ASN.2006070798
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2664-2669
    • Zhao, H.J.1    Wang, S.2    Cheng, H.3
  • 19
    • 3943073097 scopus 로고    scopus 로고
    • Glomerular endothelial dysfunction in chronic kidney disease
    • doi: 10.1081/JDI-120039524
    • Futrakul N, Panichakul T, Sirisinha S et al (2004) Glomerular endothelial dysfunction in chronic kidney disease. Ren Fail 26:259-264. doi: 10.1081/JDI-120039524
    • (2004) Ren Fail , vol.26 , pp. 259-264
    • Futrakul, N.1    Panichakul, T.2    Sirisinha, S.3
  • 20
    • 33645774175 scopus 로고    scopus 로고
    • Involvement of Rho-kinase in experimental vascular endothelial dysfunction
    • doi: 10.1007/s11010-006-2679-6
    • Shah DI, Singh M (2006) Involvement of Rho-kinase in experimental vascular endothelial dysfunction. Mol Cell Biochem 283:191-199. doi: 10.1007/s11010-006-2679-6
    • (2006) Mol Cell Biochem , vol.283 , pp. 191-199
    • Shah, D.I.1    Singh, M.2
  • 21
    • 34250797380 scopus 로고    scopus 로고
    • The Rho-kinase inhibitor, fasudil, attenuates diabetic nephropathy in streptozotocin-induced diabetic rats
    • doi: 10.1016/j.ejphar.2007.04.011
    • Gojo A, Utsunomiya K, Taniguchi K et al (2007) The Rho-kinase inhibitor, fasudil, attenuates diabetic nephropathy in streptozotocin-induced diabetic rats. Eur J Pharmacol 568:242-247. doi: 10.1016/ j.ejphar.2007.04.011
    • (2007) Eur J Pharmacol , vol.568 , pp. 242-247
    • Gojo, A.1    Utsunomiya, K.2    Taniguchi, K.3
  • 22
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • doi: 10.1038/414813a
    • Brownlee M (2001) Biochemistry and molecular cell biology of diabetic complications. Nature 414:813-820. doi: 10.1038/414813a
    • (2001) Nature , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 23
    • 33845295849 scopus 로고    scopus 로고
    • Benfotiamine prevents macro and microvascular endothelial dysfunction and oxidative stress following a meal rich in advanced glycation end products in individuals with type 2 diabetes
    • doi: 10.2337/dc06-0531
    • Stirban A, Negrean M, Stratmann B et al (2006) Benfotiamine prevents macro and microvascular endothelial dysfunction and oxidative stress following a meal rich in advanced glycation end products in individuals with type 2 diabetes. Diabetes 29:2064-2071. doi: 10.2337/dc06-0531
    • (2006) Diabetes , vol.29 , pp. 2064-2071
    • Stirban, A.1    Negrean, M.2    Stratmann, B.3
  • 24
    • 0042266256 scopus 로고    scopus 로고
    • Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine
    • doi: 10.2337/diabetes.52.8.2110
    • Babaei-Jadidi R, Karachalias N, Ahmed N et al (2003) Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine. Diabetes 52:2110-2120. doi: 10.2337/diabetes.52.8.2110
    • (2003) Diabetes , vol.52 , pp. 2110-2120
    • Babaei-Jadidi, R.1    Karachalias, N.2    Ahmed, N.3
  • 25
    • 33749350412 scopus 로고    scopus 로고
    • Benfotiamine counteracts glucose toxicity effects on endothelial progenitor cell differentiation via Akt/Foxo signaling
    • doi: 10.2337/db06-0369
    • Marchetti V, Menghini R, Rizzal S et al (2006) Benfotiamine counteracts glucose toxicity effects on endothelial progenitor cell differentiation via Akt/Foxo signaling. Diabetes 55:2231-2237. doi: 10.2337/db06-0369
    • (2006) Diabetes , vol.55 , pp. 2231-2237
    • Marchetti, V.1    Menghini, R.2    Rizzal, S.3
  • 26
    • 23644438916 scopus 로고    scopus 로고
    • Regulation of renal lipid metabolism, lipid accumulation, and glomerulosclerosis in FVB db/db mice with type 2 diabetes
    • doi: 10.2337/diabetes.54.8.2328
    • Wang Z, Jiang T, Li J et al (2005) Regulation of renal lipid metabolism, lipid accumulation, and glomerulosclerosis in FVB db/db mice with type 2 diabetes. Diabetes 54:2328-2335. doi: 10.2337/diabetes.54.8.2328
    • (2005) Diabetes , vol.54 , pp. 2328-2335
    • Wang, Z.1    Jiang, T.2    Li, J.3
  • 27
    • 34548379454 scopus 로고    scopus 로고
    • Management of dyslipidemias in patients with diabetes and chronic kidney disease
    • doi: 10.2215/CJN.00780306
    • Molitch ME (2006) Management of dyslipidemias in patients with diabetes and chronic kidney disease. Clin J Am Soc Nephrol 1:1090-1099. doi: 10.2215/CJN.00780306
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 1090-1099
    • Molitch, M.E.1
  • 28
    • 34548182594 scopus 로고    scopus 로고
    • PPAR dual agonists: Are they opening pandora's box?
    • doi: 10.1016/j.phrs.2007.03.002
    • Balakumar P, Rose M, Ganti SS et al (2007) PPAR dual agonists: Are they opening pandora's box? Pharmacol Res 56:91-98. doi: 10.1016/ j.phrs.2007.03.002
    • (2007) Pharmacol Res , vol.56 , pp. 91-98
    • Balakumar, P.1    Rose, M.2    Ganti, S.S.3
  • 29
    • 4544287560 scopus 로고    scopus 로고
    • Effect of fenofibrate on LDL-induced endothelial dysfunction in rats
    • Yang TL, Chen MF, Xia X et al (2004) Effect of fenofibrate on LDL-induced endothelial dysfunction in rats. Naunyn Schmiedebergs Arch Pharmacol 370:79-83
    • (2004) Naunyn Schmiedebergs Arch Pharmacol , vol.370 , pp. 79-83
    • Yang, T.L.1    Chen, M.F.2    Xia, X.3
  • 30
    • 33644817175 scopus 로고    scopus 로고
    • Effect of fenofibrate on the level of asymmetric dimethylarginine in individuals with hypertriglyceridemia
    • doi: 10.1007/s00228-005-0095-6
    • Yang TL, Chen MF, Xia X (2005) Effect of fenofibrate on the level of asymmetric dimethylarginine in individuals with hypertriglyceridemia. Eur J Clin Pharmacol 62:179-184. doi: 10.1007/s00228-005-0095-6
    • (2005) Eur J Clin Pharmacol , vol.62 , pp. 179-184
    • Yang, T.L.1    Chen, M.F.2    Xia, X.3
  • 31
    • 33646156170 scopus 로고    scopus 로고
    • Renoprotective effects of fenofibrate in diabetic rats are achieved by suppressing kidney plasminogen activator inhibitor-1
    • doi: 10.1016/j.vph.2006.01.004
    • Chen LL, Zhang JY, Wang BP (2006) Renoprotective effects of fenofibrate in diabetic rats are achieved by suppressing kidney plasminogen activator inhibitor-1. Vascul Pharmacol 44:309-315. doi: 10.1016/ j.vph.2006.01.004
    • (2006) Vascul Pharmacol , vol.44 , pp. 309-315
    • Chen, L.L.1    Zhang, J.Y.2    Wang, B.P.3
  • 32
    • 0018381577 scopus 로고
    • Determination of glucose in blood using glucose oxidase-peroxidase system and 8-hydroxyquinoline-p-anisidine
    • Trinder K, Hiraga Y, Nakamura N et al (1979) Determination of glucose in blood using glucose oxidase-peroxidase system and 8-hydroxyquinoline-p-anisidine. Chem Pharm Bull (Tokyo) 27:568-570
    • (1979) Chem Pharm Bull (Tokyo) , vol.27 , pp. 568-570
    • Trinder, K.1    Hiraga, Y.2    Nakamura, N.3
  • 33
    • 0016373654 scopus 로고
    • Enzymatic determination of total serum cholesterol
    • Allain CC, Poon LS, Chan CS et al (1974) Enzymatic determination of total serum cholesterol. Clin Chem 20:470
    • (1974) Clin Chem , vol.20 , pp. 470
    • Allain, C.C.1    Poon, L.S.2    Chan, C.S.3
  • 34
    • 0019420916 scopus 로고
    • Ultramicro determination of serum triglycerides by bioluminescent assay
    • Werner M, Gabrielson DJ, Eastman J (1981) Ultramicro determination of serum triglycerides by bioluminescent assay. Clin Chem 27:268-271
    • (1981) Clin Chem , vol.27 , pp. 268-271
    • Werner, M.1    Gabrielson, D.J.2    Eastman, J.3
  • 35
    • 48149110989 scopus 로고    scopus 로고
    • Effect of bis (maltolato) oxovanadium (BMOV) in uric acid and sodium arsenite-induced vascular endothelial dysfunction in rats
    • doi: 10.1016/j.ijcard.2007.05.031
    • Jindal S, Singh S, Balakumar P (2008) Effect of bis (maltolato) oxovanadium (BMOV) in uric acid and sodium arsenite-induced vascular endothelial dysfunction in rats. Int J Cardiol 128:383-391. doi: 10.1016/ j.ijcard.2007.05.031
    • (2008) Int J Cardiol , vol.128 , pp. 383-391
    • Jindal, S.1    Singh, S.2    Balakumar, P.3
  • 36
    • 0017337492 scopus 로고    scopus 로고
    • Regeneration of endothelium in rat aorta after local freezing. A scanning electron microscopic study
    • Malczak HT, Buck RC (1997) Regeneration of endothelium in rat aorta after local freezing. A scanning electron microscopic study. Am J Pathol 86:133-148
    • (1997) Am J Pathol , vol.86 , pp. 133-148
    • Malczak, H.T.1    Buck, R.C.2
  • 37
    • 0041736424 scopus 로고    scopus 로고
    • Ultrastructural evidence of early endothelial damage in coronary arteries of rat cardiac allografts
    • doi: 10.1016/S1053-2498(02)01163-4
    • Lai JCK, Tranfield EM, Walker DC et al (2003) Ultrastructural evidence of early endothelial damage in coronary arteries of rat cardiac allografts. J Heart Lung Transplant 22:993-1001. doi: 10.1016/ S1053-2498(02)01163-4
    • (2003) J Heart Lung Transplant , vol.22 , pp. 993-1001
    • Lai, J.C.K.1    Tranfield, E.M.2    Walker, D.C.3
  • 38
    • 58049137500 scopus 로고
    • The chemistry jaffe's reaction for creatinine. A red tautomer of creatinine picrate
    • Greenwald I, Gross J (1924) The chemistry jaffe's reaction for creatinine. A red tautomer of creatinine picrate. Biol Chem 59:601-612
    • (1924) Biol Chem , vol.59 , pp. 601-612
    • Greenwald, I.1    Gross, J.2
  • 39
    • 72949127206 scopus 로고
    • A rapid and precise method for the determination of urea
    • doi: 10.1136/jcp.13.2.156
    • Fawcett JK, Scott E (1960) A rapid and precise method for the determination of urea. J Clin Pathol 13:156-159. doi: 10.1136/ jcp.13.2.156
    • (1960) J Clin Pathol , vol.13 , pp. 156-159
    • Fawcett, J.K.1    Scott, E.2
  • 40
    • 0022870712 scopus 로고
    • Urinary protein as measured with a pyrogallol red-molybdate complex manually and in a hitachi 726 automated analyzer
    • Watanabe N, Kame S, Ohkubo A et al (1986) Urinary protein as measured with a pyrogallol red-molybdate complex manually and in a hitachi 726 automated analyzer. Clin Chem 32:1551-1554
    • (1986) Clin Chem , vol.32 , pp. 1551-1554
    • Watanabe, N.1    Kame, S.2    Ohkubo, A.3
  • 41
    • 12344324985 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is increased during early stage of diabetic nephropathy in type II diabetic rats
    • doi: 10.1677/joe.1.05647
    • Cha DR, Kang YS, Han SY et al (2004) Vascular endothelial growth factor is increased during early stage of diabetic nephropathy in type II diabetic rats. J Endocrinol 183:183-194. doi: 10.1677/joe.1.05647
    • (2004) J Endocrinol , vol.183 , pp. 183-194
    • Cha, D.R.1    Kang, Y.S.2    Han, S.Y.3
  • 42
    • 33847669673 scopus 로고    scopus 로고
    • Hypertension aggravates glomerular dysfunction with oxidative stress in a rat model of diabetic nephropathy
    • doi: 10.1016/j.lfs.2006.11.054
    • Tomohiro T, Kumai T, Sato T et al (2007) Hypertension aggravates glomerular dysfunction with oxidative stress in a rat model of diabetic nephropathy. Life Sci 80:1364-1372. doi: 10.1016/j.lfs.2006.11.054
    • (2007) Life Sci , vol.80 , pp. 1364-1372
    • Tomohiro, T.1    Kumai, T.2    Sato, T.3
  • 43
    • 4544349321 scopus 로고    scopus 로고
    • Effect of antioxidants and ACE inhibition on chemical modification of proteins and progression of nephropathy in the streptozotocin diabetic rat
    • doi: 10.1007/s00125-004-1474-8
    • Alderson NL, Chachich ME, Frizzel N et al (2004) Effect of antioxidants and ACE inhibition on chemical modification of proteins and progression of nephropathy in the streptozotocin diabetic rat. Diabetologia 47:1385-1395. doi: 10.1007/s00125-004-1474-8
    • (2004) Diabetologia , vol.47 , pp. 1385-1395
    • Alderson, N.L.1    Chachich, M.E.2    Frizzel, N.3
  • 44
    • 33749352941 scopus 로고    scopus 로고
    • Effect of fasudil on macrovascular disorder-induced endothelial dysfunction
    • doi: 10.1139/Y06-036
    • Shah DI, Singh M (2006) Effect of fasudil on macrovascular disorder-induced endothelial dysfunction. Can J Physiol Pharmacol 84:835-845. doi: 10.1139/Y06-036
    • (2006) Can J Physiol Pharmacol , vol.84 , pp. 835-845
    • Shah, D.I.1    Singh, M.2
  • 45
    • 31844452060 scopus 로고    scopus 로고
    • Benfotiamine accelerates the healing of ischemia diabetic limbs in mice through protein kinase B/Akt-mediated potentiation of angiogenesis and inhibition of apoptosis
    • doi: 10.1007/s00125-005-0103-5
    • Gadau S, Emanueli C, Linthout S et al (2006) Benfotiamine accelerates the healing of ischemia diabetic limbs in mice through protein kinase B/ Akt-mediated potentiation of angiogenesis and inhibition of apoptosis. Diabetologia 49:405-420. doi: 10.1007/s00125-005-0103-5
    • (2006) Diabetologia , vol.49 , pp. 405-420
    • Gadau, S.1    Emanueli, C.2    Linthout, S.3
  • 46
    • 34248662090 scopus 로고    scopus 로고
    • Fenofibrate improves age-related endothelial dysfunction in rat resistance arteries
    • doi: 10.1016/j.atherosclerosis.2006.08.041
    • De Sotomayor MA, Mingorance C, Andriantsitohaina R (2007) Fenofibrate improves age-related endothelial dysfunction in rat resistance arteries. Atherosclerosis 193:112-120. doi: 10.1016/j.atherosclerosis.2006.08.041
    • (2007) Atherosclerosis , vol.193 , pp. 112-120
    • De Sotomayor, M.A.1    Mingorance, C.2    Andriantsitohaina, R.3
  • 47
    • 0033813512 scopus 로고    scopus 로고
    • Does ADMA Cause endothelial dysfunction?
    • Cooke JP (2000) Does ADMA Cause endothelial dysfunction? Arterioscler Thromb Vasc Biol 20:2032-2037
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2032-2037
    • Cooke, J.P.1
  • 48
    • 2542617126 scopus 로고    scopus 로고
    • Medical applications of transforming growth factor-beta
    • Flanders KC, Burmester JK (2003) Medical applications of transforming growth factor-beta. Clin Med Res 1:13-20
    • (2003) Clin Med Res , vol.1 , pp. 13-20
    • Flanders, K.C.1    Burmester, J.K.2
  • 49
    • 20144386753 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 deficiency retards diabetic nephropathy
    • doi: 10.1111/j.1523-1755.2005.00207.x
    • Nicholas SB, Aguiniga E, Ren Y et al (2005) Plasminogen activator inhibitor-1 deficiency retards diabetic nephropathy. Kidney Int 67:1297-1307. doi: 10.1111/j.1523-1755.2005.00207.x
    • (2005) Kidney Int , vol.67 , pp. 1297-1307
    • Nicholas, S.B.1    Aguiniga, E.2    Ren, Y.3
  • 50
    • 0036098955 scopus 로고    scopus 로고
    • Microangiopathic injury and augmented PAI-1 in human diabetic nephropathy
    • doi: 10.1046/j.1523-1755.2002.00384.x
    • Paueksakon P, Revelo MP, Ma LJ et al (2002) Microangiopathic injury and augmented PAI-1 in human diabetic nephropathy. Kidney Int 61:2142-2148. doi: 10.1046/j.1523-1755.2002.00384.x
    • (2002) Kidney Int , vol.61 , pp. 2142-2148
    • Paueksakon, P.1    Revelo, M.P.2    Ma, L.J.3
  • 51
    • 0031128130 scopus 로고    scopus 로고
    • Albuminuria is directly associated with increased plasma PAI-1 and factor VII levels in NIDDM patients
    • doi: 10.1016/S0168-8227(97)01384-3
    • Hirano T, Kashiwazaki K, Moritomo Y et al (1997) Albuminuria is directly associated with increased plasma PAI-1 and factor VII levels in NIDDM patients. Diabetes Res Clin Pract 36:11-18. doi: 10.1016/ S0168-8227(97)01384-3
    • (1997) Diabetes Res Clin Pract , vol.36 , pp. 11-18
    • Hirano, T.1    Kashiwazaki, K.2    Moritomo, Y.3
  • 52
    • 0036068351 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 and the kidney
    • Eddy AA (2002) Plasminogen activator inhibitor-1 and the kidney. Am J Physiol Renal Physiol 283:F209-F220
    • (2002) Am J Physiol Renal Physiol , vol.283
    • Eddy, A.A.1
  • 53
    • 0025636047 scopus 로고
    • Hyperlipidaemia in diabetes
    • doi: 10.1016/S0950-351X(05)80078-3
    • Taskinen MR (1990) Hyperlipidaemia in diabetes. Baillieres Clin Endocrinol Metab 4:743-775. doi: 10.1016/S0950-351X(05)80078-3
    • (1990) Baillieres Clin Endocrinol Metab , vol.4 , pp. 743-775
    • Taskinen, M.R.1
  • 54
    • 0030295350 scopus 로고    scopus 로고
    • Effects of chronic treatment with lisinopril on cardiovascular complications in streptozotocin diabetic and DOCA hypertensive rats
    • doi: 10.1006/phrs.1996.0089
    • Sevak AR, Goyal RK (1996) Effects of chronic treatment with lisinopril on cardiovascular complications in streptozotocin diabetic and DOCA hypertensive rats. Pharmacol Res 34:201-209. doi: 10.1006/phrs.1996.0089
    • (1996) Pharmacol Res , vol.34 , pp. 201-209
    • Sevak, A.R.1    Goyal, R.K.2
  • 55
  • 56
    • 0037406315 scopus 로고    scopus 로고
    • Molecular mechanism of altered cholesterol metabolism in focal glomerulosclerosis
    • doi: 10.1046/j.1523-1755.2003.00911.x
    • Vaziri ND, Sato T, Liang K (2003) Molecular mechanism of altered cholesterol metabolism in focal glomerulosclerosis. Kidney Int 63:1756-1763. doi: 10.1046/j.1523-1755.2003.00911.x
    • (2003) Kidney Int , vol.63 , pp. 1756-1763
    • Vaziri, N.D.1    Sato, T.2    Liang, K.3
  • 57
    • 0034938227 scopus 로고    scopus 로고
    • Lisinopril improves endothelial function in chronic cigarette smokers
    • doi: 10.1042/CS20010070
    • Butler R, Morris AD, Struthers AD (2001) Lisinopril improves endothelial function in chronic cigarette smokers. Clin Sci 101:53-58. doi: 10.1042/ CS20010070
    • (2001) Clin Sci , vol.101 , pp. 53-58
    • Butler, R.1    Morris, A.D.2    Struthers, A.D.3
  • 58
    • 0042524595 scopus 로고    scopus 로고
    • ACE inhibitors improve diabetic nephropathy through suppression of renal MCP-1
    • doi: 10.2337/diacare.26.8.2421
    • Amann B, Tinzmann R, Angelkort B (2003) ACE inhibitors improve diabetic nephropathy through suppression of renal MCP-1. Diabetes 26:2421-2425. doi: 10.2337/diacare.26.8.2421
    • (2003) Diabetes , vol.26 , pp. 2421-2425
    • Amann, B.1    Tinzmann, R.2    Angelkort, B.3
  • 59
    • 0038205926 scopus 로고    scopus 로고
    • Add-on anti-TGF-β antibody to ACE inhibitor arrests progressive diabetic nephropathy in the rat
    • doi: 10.1097/01.ASN.0000074238.61967.B7
    • Benigni A, Zoja C, Corna D et al (2003) Add-on anti-TGF-β antibody to ACE inhibitor arrests progressive diabetic nephropathy in the rat. J Am Soc Nephrol 14:1816-1824. doi: 10.1097/01.ASN.0000074238.61967.B7
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1816-1824
    • Benigni, A.1    Zoja, C.2    Corna, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.