메뉴 건너뛰기




Volumn 121, Issue 1, 2009, Pages 98-105

KD-501, a standardized extract of Scrophularia buergeriana has both cognitive-enhancing and antioxidant activities in mice given scopolamine

Author keywords

Acetylcholinesterase; Alzheimer's disease; Antioxidant activity; Cognitive enhancing activity; KD 501; Scrophularia buergeriana

Indexed keywords

ACETYLCHOLINESTERASE; CENTRAL STIMULANT AGENT; GLUTATHIONE; GLUTATHIONE REDUCTASE; KD 501; SCOPOLAMINE; SCROPHULARIA BUERGERIANA EXTRACT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

EID: 58049127052     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2008.10.006     Document Type: Article
Times cited : (50)

References (49)
  • 1
    • 0031033149 scopus 로고    scopus 로고
    • Antioxidant activity of peptide fractions of capelin protein hydrolysates
    • Amarowicz R., and Shahidi F. Antioxidant activity of peptide fractions of capelin protein hydrolysates. Food Chemistry 58 (1997) 355-359
    • (1997) Food Chemistry , vol.58 , pp. 355-359
    • Amarowicz, R.1    Shahidi, F.2
  • 3
    • 0019972810 scopus 로고
    • The cholinergic hypothesis of geriatric memory dysfunction
    • Bartus R.T., Dean III R.L., Beer B., and Lippa A.S. The cholinergic hypothesis of geriatric memory dysfunction. Science 217 (1982) 408-414
    • (1982) Science , vol.217 , pp. 408-414
    • Bartus, R.T.1    Dean III, R.L.2    Beer, B.3    Lippa, A.S.4
  • 4
    • 0022636674 scopus 로고
    • Patterns of memory failure after scopolamine treatment: implications for cholinergic hypothesis of dementia
    • Beatty W.W., Butters N., and Janowsky D.S. Patterns of memory failure after scopolamine treatment: implications for cholinergic hypothesis of dementia. Behavioral and Neural Biology 45 (1986) 196-211
    • (1986) Behavioral and Neural Biology , vol.45 , pp. 196-211
    • Beatty, W.W.1    Butters, N.2    Janowsky, D.S.3
  • 5
    • 0032763708 scopus 로고    scopus 로고
    • Effect of rivastigmine on scopolamine-induced memory impairment in rats
    • Bejar C., Wang R.H., and Weinstock M. Effect of rivastigmine on scopolamine-induced memory impairment in rats. European Journal of Pharmacology 383 (1999) 231-240
    • (1999) European Journal of Pharmacology , vol.383 , pp. 231-240
    • Bejar, C.1    Wang, R.H.2    Weinstock, M.3
  • 6
    • 0029553116 scopus 로고
    • Acetylcholine: a neurotransmitter for learning and memory?
    • Blokland A. Acetylcholine: a neurotransmitter for learning and memory?. Brain Research 21 (1995) 285-300
    • (1995) Brain Research , vol.21 , pp. 285-300
    • Blokland, A.1
  • 7
    • 0030014585 scopus 로고    scopus 로고
    • An inverted U-shaped curve for heptylphysostigmine on radial maze performance in rats: comparison with other cholinesterase inhibitors
    • Braida D., Paladini E., Griffini P., Lamerti M., Maggi A., and Sala M. An inverted U-shaped curve for heptylphysostigmine on radial maze performance in rats: comparison with other cholinesterase inhibitors. European Journal of Pharmacology 302 (1996) 13-20
    • (1996) European Journal of Pharmacology , vol.302 , pp. 13-20
    • Braida, D.1    Paladini, E.2    Griffini, P.3    Lamerti, M.4    Maggi, A.5    Sala, M.6
  • 8
    • 0016808562 scopus 로고
    • Purification and characterization of the flavoenzyme glutathione reductase from rat liver
    • Carlberg I., and Mannervik B. Purification and characterization of the flavoenzyme glutathione reductase from rat liver. The Journal of Biological Chemistry 25 (1975) 5475-5480
    • (1975) The Journal of Biological Chemistry , vol.25 , pp. 5475-5480
    • Carlberg, I.1    Mannervik, B.2
  • 9
    • 0025832844 scopus 로고
    • Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity and loss in temporal and spatial memory by chronic administration of the spin trapping compound N-tert-butyl-a-phenylnitrone
    • Carney J.M., Starke-Reed P.E., Oliver C.N., Landum R.W., Cheng M.S., and Wu J.F. Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity and loss in temporal and spatial memory by chronic administration of the spin trapping compound N-tert-butyl-a-phenylnitrone. Proceedings of the National Academy of Sciences of the United States of America 88 (1991) 3633-3666
    • (1991) Proceedings of the National Academy of Sciences of the United States of America , vol.88 , pp. 3633-3666
    • Carney, J.M.1    Starke-Reed, P.E.2    Oliver, C.N.3    Landum, R.W.4    Cheng, M.S.5    Wu, J.F.6
  • 10
    • 0028385744 scopus 로고
    • Regional brain activity of free radical defense enzyme in autopsy samples from patients with Alzheimer's disease and from nondemented controls
    • Chen L., Richardson J.S., Caldwell J.E., and Ang L.C. Regional brain activity of free radical defense enzyme in autopsy samples from patients with Alzheimer's disease and from nondemented controls. The International Journal of Neuroscience 75 (1994) 83-90
    • (1994) The International Journal of Neuroscience , vol.75 , pp. 83-90
    • Chen, L.1    Richardson, J.S.2    Caldwell, J.E.3    Ang, L.C.4
  • 11
    • 0032101015 scopus 로고    scopus 로고
    • Comparative studies of huperzine A, E2020, and tacrine on behavior and cholinesterase activities
    • Cheng D.H., and Tang X.C. Comparative studies of huperzine A, E2020, and tacrine on behavior and cholinesterase activities. Pharmacology, Biochemistry, and Behavior 60 (1998) 377-386
    • (1998) Pharmacology, Biochemistry, and Behavior , vol.60 , pp. 377-386
    • Cheng, D.H.1    Tang, X.C.2
  • 12
    • 0022875838 scopus 로고
    • Cholinergic function and intellectual decline in Alzheimer's disease
    • Collerton D. Cholinergic function and intellectual decline in Alzheimer's disease. Neuroscience 19 (1986) 1-28
    • (1986) Neuroscience , vol.19 , pp. 1-28
    • Collerton, D.1
  • 13
    • 0026005792 scopus 로고
    • The behavioral effects of heptylphysostigmine, a new cholinesterase inhibitor, in tests of long-term and working memory in rodents
    • Dawson G.R., Bentley G., Drapper F., Rycroft W., Iversen S.D., and Pagella P.G. The behavioral effects of heptylphysostigmine, a new cholinesterase inhibitor, in tests of long-term and working memory in rodents. Pharmacology, Biochemistry, and Behavior 39 (1991) 865-871
    • (1991) Pharmacology, Biochemistry, and Behavior , vol.39 , pp. 865-871
    • Dawson, G.R.1    Bentley, G.2    Drapper, F.3    Rycroft, W.4    Iversen, S.D.5    Pagella, P.G.6
  • 15
    • 0031744035 scopus 로고    scopus 로고
    • Scopolamine model of dementia: electroencephalogram findings and cognitive performance
    • Ebert U., and Kirch W. Scopolamine model of dementia: electroencephalogram findings and cognitive performance. European Journal of Clinical Investigation 28 (1998) 944-949
    • (1998) European Journal of Clinical Investigation , vol.28 , pp. 944-949
    • Ebert, U.1    Kirch, W.2
  • 16
    • 0345708155 scopus 로고    scopus 로고
    • Hypericum perforatum extract demonstrates antioxidant properties against elevated rat brain oxidative status induced by amnestic dose of scopolamine
    • El-Sherbiny D.A., Khalifa A.E., Attia A.S., and Eldenshary E.E.S. Hypericum perforatum extract demonstrates antioxidant properties against elevated rat brain oxidative status induced by amnestic dose of scopolamine. Pharmacology, Biochemistry, and Behavior 76 (2003) 523-533
    • (2003) Pharmacology, Biochemistry, and Behavior , vol.76 , pp. 523-533
    • El-Sherbiny, D.A.1    Khalifa, A.E.2    Attia, A.S.3    Eldenshary, E.E.S.4
  • 18
    • 0021288821 scopus 로고
    • Assays of glutathione peroxidase
    • Flohe L., and Gunzler W.A. Assays of glutathione peroxidase. Methods in Enzymology 105 (1984) 114-121
    • (1984) Methods in Enzymology , vol.105 , pp. 114-121
    • Flohe, L.1    Gunzler, W.A.2
  • 23
    • 58049123160 scopus 로고    scopus 로고
    • JiansuNewMedical College (Ed.), 1997. Dictionary of Chinese Crude Drugs. Shanghai Scientific Technology Publisher, Shanghai, p. 769.
    • JiansuNewMedical College (Ed.), 1997. Dictionary of Chinese Crude Drugs. Shanghai Scientific Technology Publisher, Shanghai, p. 769.
  • 25
    • 33646095419 scopus 로고
    • Phenolic constituents in the leaves of northern willows, methods for the analysis of certain phenolics
    • Julkunen-Tiito R. Phenolic constituents in the leaves of northern willows, methods for the analysis of certain phenolics. Journal of Agricultural and Food Chemistry 33 (1985) 213-217
    • (1985) Journal of Agricultural and Food Chemistry , vol.33 , pp. 213-217
    • Julkunen-Tiito, R.1
  • 26
    • 0030920835 scopus 로고    scopus 로고
    • The antioxidant activity of sine and its consequences on the volatile profiles of liposomes during iron/ascorbate induced phospholipids oxidation
    • Kansci G., Genot C., Meynier A., and Gandemer G. The antioxidant activity of sine and its consequences on the volatile profiles of liposomes during iron/ascorbate induced phospholipids oxidation. Food Chemistry 60 (1997) 165-175
    • (1997) Food Chemistry , vol.60 , pp. 165-175
    • Kansci, G.1    Genot, C.2    Meynier, A.3    Gandemer, G.4
  • 29
    • 0000103844 scopus 로고    scopus 로고
    • Neuroprotective phenylpropanoid esters of rhamnose isolated from roots of Scrophularia buergeriana
    • Kim S.R., and Kim Y.C. Neuroprotective phenylpropanoid esters of rhamnose isolated from roots of Scrophularia buergeriana. Phytochemistry 54 (2000) 503-509
    • (2000) Phytochemistry , vol.54 , pp. 503-509
    • Kim, S.R.1    Kim, Y.C.2
  • 30
    • 0345171432 scopus 로고    scopus 로고
    • Iridoids from Scrophularia buergeriana attenuate glutamate-induced neurotoxicity in rat cortical cultures
    • Kim S.R., Koo K.A., Sung S.H., Ma C.J., Yoon J.S., and Kim Y.C. Iridoids from Scrophularia buergeriana attenuate glutamate-induced neurotoxicity in rat cortical cultures. Journal of Neuroscience Research 74 (2003) 948-955
    • (2003) Journal of Neuroscience Research , vol.74 , pp. 948-955
    • Kim, S.R.1    Koo, K.A.2    Sung, S.H.3    Ma, C.J.4    Yoon, J.S.5    Kim, Y.C.6
  • 32
    • 0036202359 scopus 로고    scopus 로고
    • E-p-Methoxycinnamic acid protects cultured neuronal cells against neurotoxicity induced by glutamate
    • Kim S.R., Sung S.H., Jang Y.P., Markelonis G.J., Oh T.H., and Kim Y.C. E-p-Methoxycinnamic acid protects cultured neuronal cells against neurotoxicity induced by glutamate. British Journal of Pharmacology 135 (2002) 1281-1291
    • (2002) British Journal of Pharmacology , vol.135 , pp. 1281-1291
    • Kim, S.R.1    Sung, S.H.2    Jang, Y.P.3    Markelonis, G.J.4    Oh, T.H.5    Kim, Y.C.6
  • 33
    • 0023808332 scopus 로고    scopus 로고
    • Cholinergic "blockage" as a model of cholinergic depletion
    • Kopolman M.D., and Corn T.H. Cholinergic "blockage" as a model of cholinergic depletion. Brain 111 (1998) 1079-1110
    • (1998) Brain , vol.111 , pp. 1079-1110
    • Kopolman, M.D.1    Corn, T.H.2
  • 34
    • 35648938731 scopus 로고    scopus 로고
    • Simultaneous determination of four active constituents in the roots of Schrophularia buergeriana by HPLC-DAD and LC-ESI-MS
    • Lee M.K., Choi O.G., Park J.H., Cho H.J., Ahn M.J., Kim S.H., Kim Y.C., and Sung S.H. Simultaneous determination of four active constituents in the roots of Schrophularia buergeriana by HPLC-DAD and LC-ESI-MS. Journal of Separation Science 30 (2007) 2345-2350
    • (2007) Journal of Separation Science , vol.30 , pp. 2345-2350
    • Lee, M.K.1    Choi, O.G.2    Park, J.H.3    Cho, H.J.4    Ahn, M.J.5    Kim, S.H.6    Kim, Y.C.7    Sung, S.H.8
  • 35
    • 0033067354 scopus 로고    scopus 로고
    • Regulation of hepatic glutathione synthesis: current concepts and controversies
    • Lu S.C. Regulation of hepatic glutathione synthesis: current concepts and controversies. The FASEB Journal 13 (1999) 1169-1183
    • (1999) The FASEB Journal , vol.13 , pp. 1169-1183
    • Lu, S.C.1
  • 36
    • 0031020521 scopus 로고    scopus 로고
    • Antioxidative activity of extracts from selected species of the family Lamiaceae in sunflower oil
    • Marinova E.M., and Yanishlieva N.V. Antioxidative activity of extracts from selected species of the family Lamiaceae in sunflower oil. Food Chemistry 58 (1997) 245-248
    • (1997) Food Chemistry , vol.58 , pp. 245-248
    • Marinova, E.M.1    Yanishlieva, N.V.2
  • 37
    • 0032454039 scopus 로고    scopus 로고
    • Effects of amyloid precursor protein derivatives and oxidative stress on basal forebrain cholinergic systems in Alzheimer's disease
    • Mattson M.P., and Pedersen W.A. Effects of amyloid precursor protein derivatives and oxidative stress on basal forebrain cholinergic systems in Alzheimer's disease. International Journal of Development Neuroscience 16 (1998) 626-642
    • (1998) International Journal of Development Neuroscience , vol.16 , pp. 626-642
    • Mattson, M.P.1    Pedersen, W.A.2
  • 38
    • 0014691273 scopus 로고
    • The utility of superoxide dismutase in studying free radical reactions. I. Radicals generated by interaction of sulfite, dimethyl sulfoxide, and oxygen
    • McCord J.M., and Fridovich I. The utility of superoxide dismutase in studying free radical reactions. I. Radicals generated by interaction of sulfite, dimethyl sulfoxide, and oxygen. The Journal of Biological Chemistry 25 (1969) 6056-6063
    • (1969) The Journal of Biological Chemistry , vol.25 , pp. 6056-6063
    • McCord, J.M.1    Fridovich, I.2
  • 39
    • 0021173996 scopus 로고
    • Development of a water maze procedure for studying spatial learning in the rat
    • Morris R.G. Development of a water maze procedure for studying spatial learning in the rat. Journal of Neuroscience Methods 11 (1984) 47-60
    • (1984) Journal of Neuroscience Methods , vol.11 , pp. 47-60
    • Morris, R.G.1
  • 40
    • 58049087267 scopus 로고    scopus 로고
    • Muanza, D., Robert, R., Sparks, W., 1998. Antioxidant derived from lentil and its preparation and uses. U.S. Patent US5,762,936.
    • Muanza, D., Robert, R., Sparks, W., 1998. Antioxidant derived from lentil and its preparation and uses. U.S. Patent US5,762,936.
  • 41
    • 0030607694 scopus 로고    scopus 로고
    • d-Cycloserine, a glycine site agonist, reverses working memory failure by hippocampal muscarinic receptor in rats
    • Ohno M., and Watanabe S. d-Cycloserine, a glycine site agonist, reverses working memory failure by hippocampal muscarinic receptor in rats. European Journal of Pharmacology 318 (1996) 267-271
    • (1996) European Journal of Pharmacology , vol.318 , pp. 267-271
    • Ohno, M.1    Watanabe, S.2
  • 42
    • 0032917662 scopus 로고    scopus 로고
    • The activity of the pentose phosphate pathway is increased in response to oxidative stress in Alzheimer's disease
    • Palmer A.M. The activity of the pentose phosphate pathway is increased in response to oxidative stress in Alzheimer's disease. Journal of Neural Transmission 106 (1999) 317-328
    • (1999) Journal of Neural Transmission , vol.106 , pp. 317-328
    • Palmer, A.M.1
  • 44
    • 0037321379 scopus 로고    scopus 로고
    • Oxidative stress in neurodegenerative disease: therapeutic implications for superoxide dismutase mimetics
    • Pong K. Oxidative stress in neurodegenerative disease: therapeutic implications for superoxide dismutase mimetics. Expert Opinion on Biological Therapy 3 (2003) 127-139
    • (2003) Expert Opinion on Biological Therapy , vol.3 , pp. 127-139
    • Pong, K.1
  • 46
    • 0014481378 scopus 로고
    • Enzymatic method of quantitative determination of nanogram amounts of total and oxidized glutathione
    • Tietz F. Enzymatic method of quantitative determination of nanogram amounts of total and oxidized glutathione. Analytical Biochemistry 27 (1969) 502-522
    • (1969) Analytical Biochemistry , vol.27 , pp. 502-522
    • Tietz, F.1
  • 49
    • 0024490143 scopus 로고
    • Superoxide dismutase activity in Alzheimer's disease: possible mechanism for paired helical filament formation
    • Zemlan F.P., Thienhaus O.J., and Bosmann H.B. Superoxide dismutase activity in Alzheimer's disease: possible mechanism for paired helical filament formation. Brain Research 476 (1989) 160-162
    • (1989) Brain Research , vol.476 , pp. 160-162
    • Zemlan, F.P.1    Thienhaus, O.J.2    Bosmann, H.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.