메뉴 건너뛰기




Volumn 22, Issue 12, 2008, Pages 2169-2175

SOCS2: Inhibitor of JAK2V617F-mediated signal transduction

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; CYTOKINE RECEPTOR; ERYTHROPOIETIN; GRANULOCYTE COLONY STIMULATING FACTOR; GROWTH FACTOR; JANUS KINASE 2; PHENYLALANINE; STAT5 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 2; TRANSCRIPTION FACTOR; VALINE;

EID: 57949086449     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2008.226     Document Type: Article
Times cited : (38)

References (30)
  • 7
    • 33644867711 scopus 로고    scopus 로고
    • Epigenetic modification of SOCS-1 differentially regulates STAT3 activation in response to interleukin-6 receptor and epidermal growth factor receptor signaling through JAK and/ or MEK in head and neck squamous cell carcinomas
    • Lee TL, Yeh J, van Waes C, Chen Z. Epigenetic modification of SOCS-1 differentially regulates STAT3 activation in response to interleukin-6 receptor and epidermal growth factor receptor signaling through JAK and/ or MEK in head and neck squamous cell carcinomas. Mol Cancer Ther 2006; 5: 8-19.
    • (2006) Mol Cancer Ther , vol.5 , pp. 8-19
    • Lee, T.L.1    Yeh, J.2    van Waes, C.3    Chen, Z.4
  • 8
    • 27144433826 scopus 로고    scopus 로고
    • Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma
    • Niwa Y, Kanda H, Shikauchi Y, Saiura Y, Matsubara K, Kitagawa T et al Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma. Oncogene 2006; 24: 6404-6417.
    • (2006) Oncogene , vol.24 , pp. 6404-6417
    • Niwa, Y.1    Kanda, H.2    Shikauchi, Y.3    Saiura, Y.4    Matsubara, K.5    Kitagawa, T.6
  • 9
    • 24944476696 scopus 로고    scopus 로고
    • Hypermethylation of the suppressor of cytokine signalling-1 (SOCS-1) in myelodysplastic syndrome
    • Brakensiek K, Länger F, Schlegelberger B, Kreipe H, Lehmann U. Hypermethylation of the suppressor of cytokine signalling-1 (SOCS-1) in myelodysplastic syndrome. Br J Haematol 2005; 130: 209-217.
    • (2005) Br J Haematol , vol.130 , pp. 209-217
    • Brakensiek, K.1    Länger, F.2    Schlegelberger, B.3    Kreipe, H.4    Lehmann, U.5
  • 10
    • 33847223121 scopus 로고    scopus 로고
    • Epigenetic alterations complement mutation of JAK2 tyrosine kinase in patients with BCR/ABL1-negative myeloproliferative disorders
    • Jost E, do ÓN, Dahl E, Maintz CE, Jousten P, Habets L et al. Epigenetic alterations complement mutation of JAK2 tyrosine kinase in patients with BCR/ABL1-negative myeloproliferative disorders. Leukemia 2007; 21: 505-510.
    • (2007) Leukemia , vol.21 , pp. 505-510
    • Jost, E.1    Dahl, E.2    Maintz, C.E.3    Jousten, P.4    Habets, L.5
  • 11
    • 34250207360 scopus 로고    scopus 로고
    • Rearrangements involving 12q in myeloproliferative disorders: Possible role of HMGA2 and SOCS2 genes
    • Etienne A, Carbuccia N, Adelaide J, Bekhouche I, Remy V, Sohn C et al Rearrangements involving 12q in myeloproliferative disorders: possible role of HMGA2 and SOCS2 genes. Cancer Genet Cytogenet 2007; 176: 80-88.
    • (2007) Cancer Genet Cytogenet , vol.176 , pp. 80-88
    • Etienne, A.1    Carbuccia, N.2    Adelaide, J.3    Bekhouche, I.4    Remy, V.5    Sohn, C.6
  • 12
    • 30044437118 scopus 로고    scopus 로고
    • Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation
    • Lu X, Levine R, Tong W, Wernig G, Pikman Y, Zarnegar S et al. Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation. Proc Natl Acad Sci USA 2005; 102: 18962-18967.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 18962-18967
    • Lu, X.1    Levine, R.2    Tong, W.3    Wernig, G.4    Pikman, Y.5    Zarnegar, S.6
  • 13
    • 41949118675 scopus 로고    scopus 로고
    • Dimerization by a cytokine receptor is necessary for constitutive activation of JAK2V617F
    • Lu X, Huang LJS, Lodish HF. Dimerization by a cytokine receptor is necessary for constitutive activation of JAK2V617F. J Biol Chem 2008; 283: 5258-5266.
    • (2008) J Biol Chem , vol.283 , pp. 5258-5266
    • Lu, X.1    Huang, L.J.S.2    Lodish, H.F.3
  • 14
    • 33644546402 scopus 로고    scopus 로고
    • JAK2V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders
    • Quentmeier H, MacLeod RAF, Zaborski M, Drexler HG. JAK2V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders. Leukemia 2006; 20: 471-476.
    • (2006) Leukemia , vol.20 , pp. 471-476
    • Quentmeier, H.1    MacLeod, R.A.F.2    Zaborski, M.3    Drexler, H.G.4
  • 15
    • 0025719947 scopus 로고
    • Granulocyte-macrophage colony-stimulating factor-dependent growth and erythropoietin-induced differentiation of a human cell line MB-02
    • Morgan DA, Gumucio DL, Brodsky I. Granulocyte-macrophage colony-stimulating factor-dependent growth and erythropoietin-induced differentiation of a human cell line MB-02. Blood 1991; 78: 2860-2871.
    • (1991) Blood , vol.78 , pp. 2860-2871
    • Morgan, D.A.1    Gumucio, D.L.2    Brodsky, I.3
  • 17
    • 0028962455 scopus 로고
    • Establishment of a myeloid leukaemic cell line (SKNO-1) from a patient with t(8;21) who acquired monosomy 17 during disease progression
    • Matozaki S, Nakagawa T, Kawaguchi R, Aozaki R, Tsutsumi M, Murayama T et al. Establishment of a myeloid leukaemic cell line (SKNO-1) from a patient with t(8;21) who acquired monosomy 17 during disease progression. Br J Haematol 1995; 89: 805-811.
    • (1995) Br J Haematol , vol.89 , pp. 805-811
    • Matozaki, S.1    Nakagawa, T.2    Kawaguchi, R.3    Aozaki, R.4    Tsutsumi, M.5    Murayama, T.6
  • 18
    • 0034650193 scopus 로고    scopus 로고
    • Derivation of a new hematopoietic cell line with endothelial features from a patient with transformed myeloproliferative syndrome
    • Fiedler W, Henke RP, Ergün S, Schumacher U, Gehling UM, Vohwinkel G et al. Derivation of a new hematopoietic cell line with endothelial features from a patient with transformed myeloproliferative syndrome. Cancer 2000; 88: 344-351.
    • (2000) Cancer , vol.88 , pp. 344-351
    • Fiedler, W.1    Henke, R.P.2    Ergün, S.3    Schumacher, U.4    Gehling, U.M.5    Vohwinkel, G.6
  • 20
    • 0034882530 scopus 로고    scopus 로고
    • Cloning of human thymic stromal lymphopoietin (TSLP) and signaling mechanisms leading to proliferation
    • Quentmeier H, Drexler HG, Fleckenstein D, Zaborski M, Armstrong A, Sims JE et al. Cloning of human thymic stromal lymphopoietin (TSLP) and signaling mechanisms leading to proliferation. Leukemia 2001; 15: 1286-1292.
    • (2001) Leukemia , vol.15 , pp. 1286-1292
    • Quentmeier, H.1    Drexler, H.G.2    Fleckenstein, D.3    Zaborski, M.4    Armstrong, A.5    Sims, J.E.6
  • 21
    • 34347247338 scopus 로고    scopus 로고
    • Cytogenetic harvesting of commonly used tumor cell lines
    • MacLeod RAF, Kaufmann M, Drexler HG. Cytogenetic harvesting of commonly used tumor cell lines. Nat Protoc 2007; 2: 372-382.
    • (2007) Nat Protoc , vol.2 , pp. 372-382
    • MacLeod, R.A.F.1    Kaufmann, M.2    Drexler, H.G.3
  • 22
    • 0141611749 scopus 로고    scopus 로고
    • Modulation of gene expression by lentiviral-mediated delivery of small interfering RNA
    • Scherr M, Battmer K, Ganser A, Eder M. Modulation of gene expression by lentiviral-mediated delivery of small interfering RNA. Cell Cycle 2003; 3: 251-257.
    • (2003) Cell Cycle , vol.3 , pp. 251-257
    • Scherr, M.1    Battmer, K.2    Ganser, A.3    Eder, M.4
  • 23
    • 0037079742 scopus 로고    scopus 로고
    • Lentiviral gene transfer into peripheral blood-derived CD34+ NOD/SCID-repopulating cells
    • Scherr M, Battmer K, Blömer U, Schiedlmeier B, Ganser A, Grez M et al. Lentiviral gene transfer into peripheral blood-derived CD34+ NOD/SCID-repopulating cells. Blood 2002; 99: 709-712.
    • (2002) Blood , vol.99 , pp. 709-712
    • Scherr, M.1    Battmer, K.2    Blömer, U.3    Schiedlmeier, B.4    Ganser, A.5    Grez, M.6
  • 24
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine RL, Madleigh M, Cools J, Ebert BL, Wernig G, Huntly BJP et al Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 2005; 7: 387-397.
    • (2005) Cancer Cell , vol.7 , pp. 387-397
    • Levine, R.L.1    Madleigh, M.2    Cools, J.3    Ebert, B.L.4    Wernig, G.5    Huntly, B.J.P.6
  • 26
    • 34247265497 scopus 로고    scopus 로고
    • Overexpression of SOCS-2 and SOCS-3 genes reverses erythorid overgrowth and IGF-I hypersensitivity of primary polycythemia vera (PV) cells
    • Usenko T, Eskinazi D, Correa PN, Amato D, Ben-David Y, Axelrad AA. Overexpression of SOCS-2 and SOCS-3 genes reverses erythorid overgrowth and IGF-I hypersensitivity of primary polycythemia vera (PV) cells. Leuk Lymphoma 2007; 48: 134-146.
    • (2007) Leuk Lymphoma , vol.48 , pp. 134-146
    • Usenko, T.1    Eskinazi, D.2    Correa, P.N.3    Amato, D.4    Ben-David, Y.5    Axelrad, A.A.6
  • 28
    • 34249728880 scopus 로고    scopus 로고
    • The myeloproliferative disorder-associated JAK2 V617F mutant escapes negative regulation by suppressor of cytokine signaling 3
    • Hookham MB, Elliott J, Suessmuth Y, Staerk J, Ward AC, Vainchenker W et al. The myeloproliferative disorder-associated JAK2 V617F mutant escapes negative regulation by suppressor of cytokine signaling 3. Blood 2007; 109: 4924-4929.
    • (2007) Blood , vol.109 , pp. 4924-4929
    • Hookham, M.B.1    Elliott, J.2    Suessmuth, Y.3    Staerk, J.4    Ward, A.C.5    Vainchenker, W.6
  • 29
    • 0036408435 scopus 로고    scopus 로고
    • Differential roles of SOCS family members in EpoR signal transduction
    • Jegalian AG, Wu H. Differential roles of SOCS family members in EpoR signal transduction. J Interferon Cytokine Res 2002; 22: 853-860.
    • (2002) J Interferon Cytokine Res , vol.22 , pp. 853-860
    • Jegalian, A.G.1    Wu, H.2
  • 30
    • 35348868573 scopus 로고    scopus 로고
    • Epigenetic regulation of normal and malignant hematopoiesis
    • Rice KL, Hormaeche I, Licht JD. Epigenetic regulation of normal and malignant hematopoiesis. Oncogene 2007; 26: 6697-6714.
    • (2007) Oncogene , vol.26 , pp. 6697-6714
    • Rice, K.L.1    Hormaeche, I.2    Licht, J.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.