Lap3 is a selective target of autophagy in yeast, Saccharomyces cerevisiae

Biochemical and Biophysical Research Communications

Volumn 378, Issue 3, 2009, Pages 551-557

  Kageyama, Takuya ^a,b   Suzuki, Kuninori ^a,b   Ohsumi, Yoshinori ^a,b  

^a NATIONAL INSTITUTE FOR BASIC BIOLOGY   (Japan)

^b GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

Author keywords

Bleomycin hydrolase; Cvt complex; Lap3; Protein degradation; Selective autophagy; Yeast

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE 6; AMINOPEPTIDASE I; CYTOSOL AMINOPEPTIDASE; CYTOSOL AMINOPEPTIDASE III; DEOXYRIBONUCLEASE I; NITROGEN; UNCLASSIFIED DRUG;

ARTICLE; ATG11 GENE; ATG19 GENE; AUTOPHAGY; CELL VACUOLE; CONTROLLED STUDY; GENE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE;

AMINOPEPTIDASES; AUTOPHAGY; CYSTEINE ENDOPEPTIDASES; DNA-BINDING PROTEINS; NITROGEN; PROTEIN KINASES; PROTEIN TRANSPORT; RECEPTORS, CELL SURFACE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; VACUOLES; VESICULAR TRANSPORT PROTEINS;

SACCHAROMYCES CEREVISIAE;

EID: 57749173129     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.11.084     Document Type: Article

References (30)

1. Mizushima N. Autophagy: process and function. Genes Dev. 21 (2007) 2861-2873
2. Takeshige K., Baba M., Tsuboi S., Noda T., and Ohsumi Y. Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction. J. Cell Biol. 119 (1992) 301-311
3. Rubinsztein D.C. The roles of intracellular protein-degradation pathways in neurodegeneration. Nature 443 (2006) 780-786
4. Sakai Y., Oku M., van der Klei I.J., and Kiel J.A. Pexophagy: autophagic degradation of peroxisomes. Biochim. Biophys. Acta 1763 (2006) 1767-1775
5. Kanki T., and Klionsky D.J. Mitophagy in yeast occurs through a selective mechanism. J. Biol. Chem. 283 (2008) 32386-32393
6. Kraft C., Deplazes A., Sohrmann M., and Peter M. Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease. Nat. Cell Biol. 10 (2008) 602-610
7. Onodera J., and Ohsumi Y. Ald6p is a preferred target for autophagy in yeast, Saccharomyces cerevisiae. J. Biol. Chem. 279 (2004) 16071-16076
8. Baba M., Osumi M., Scott S.V., Klionsky D.J., and Ohsumi Y. Two distinct pathways for targeting proteins from the cytoplasm to the vacuole/lysosome. J. Cell Biol. 139 (1997) 1687-1695
9. Yorimitsu T., and Klionsky D.J. Atg11 links cargo to the vesicle-forming machinery in the cytoplasm to vacuole targeting pathway. Mol. Biol. Cell 16 (2005) 1593-1605
10. Kim J., Scott S.V., Oda M.N., and Klionsky D.J. Transport of a large oligomeric protein by the cytoplasm to vacuole protein targeting pathway. J. Cell Biol. 137 (1997) 609-618
11. Oda M.N., Scott S.V., Hefner-Gravink A., Caffarelli A.D., and Klionsky D.J. Identification of a cytoplasm to vacuole targeting determinant in aminopeptidase I. J. Cell Biol. 132 (1996) 999-1010
12. Scott S.V., Guan J., Hutchins M.U., Kim J., and Klionsky D.J. Cvt19 is a receptor for the cytoplasm-to-vacuole targeting pathway. Mol. Cell 7 (2001) 1131-1141
13. Shintani T., Huang W.P., Stromhaug P.E., and Klionsky D.J. Mechanism of cargo selection in the cytoplasm to vacuole targeting pathway. Dev. Cell 3 (2002) 825-837
14. Klionsky D.J., Cueva R., and Yaver D.S. Aminopeptidase I of Saccharomyces cerevisiae is localized to the vacuole independent of the secretory pathway. J. Cell Biol. 119 (1992) 287-299
15. Kabeya Y., Kawamata T., Suzuki K., and Ohsumi Y. Cis1/Atg31 is required for autophagosome formation in Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 356 (2007) 405-410
16. Kawamata T., Kamada Y., Kabeya Y., Sekito T., and Ohsumi Y. Organization of the pre-autophagosomal structure responsible for autophagosome formation. Mol. Biol. Cell 19 (2008) 2039-2050
17. Trumbly R.J., and Bradley G. Isolation and characterization of aminopeptidase mutants of Saccharomyces cerevisiae. J. Bacteriol. 156 (1983) 36-48
18. Joshua-Tor L., Xu H.E., Johnston S.A., and Rees D.C. Crystal structure of a conserved protease that binds DNA: the bleomycin hydrolase, Gal6. Science 269 (1995) 945-950
19. Enenkel C., and Wolf D.H. BLH1 codes for a yeast thiol aminopeptidase, the equivalent of mammalian bleomycin hydrolase. J. Biol. Chem. 268 (1993) 7036-7043
20. O'Farrell P.A., Gonzalez F., Zheng W., Johnston S.A., and Joshua-Tor L. Crystal structure of human bleomycin hydrolase A self-compartmentalizing cysteine protease. Structure 7 (1999) 619-627
21. Bruke D., Dawson D., and Stearn T. Method in Yeast Genetics (2005), Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
22. Longtine M.S., McKenzie III A., Demarini D.J., Shah N.G., Wach A., Brachat A., Philippsen P., and Pringle J.R. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14 (1998) 953-961
23. Janke C., Magiera M.M., Rathfelder N., Taxis C., Reber S., Maekawa H., Moreno-Borchart A., Doenges G., Schwob E., Schiebel E., and Knop M. A versatile toolbox for PCR-based tagging of yeast genes: new fluorescent proteins More markers and promoter substitution cassettes. Yeast 21 (2004) 947-962
24. Suzuki K., Kirisako T., Kamada Y., Mizushima N., Noda T., and Ohsumi Y. The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation. EMBO J. 20 (2001) 5971-5981
25. Stromhaug P.E., Reggiori F., Guan J., Wang C.W., and Klionsky D.J. Atg21 is a phosphoinositide binding protein required for efficient lipidation and localization of Atg8 during uptake of aminopeptidase I by selective autophagy. Mol. Biol. Cell 15 (2004) 3553-3566
26. Suzuki K., Kubota Y., Sekito T., and Ohsumi Y. Hierarchy of Atg proteins in pre-autophagosomal structure organization. Genes Cells 12 (2007) 209-218
27. Shintani T., and Klionsky D.J. Cargo proteins facilitate the formation of transport vesicles in the cytoplasm to vacuole targeting pathway. J. Biol. Chem. 279 (2004) 29889-29894
28. Suzuki K., Kamada Y., and Ohsumi Y. Studies of cargo delivery to the vacuole mediated by autophagosomes in Saccharomyces cerevisiae. Dev. Cell 3 (2002) 815-824
29. Reggiori F., Monastyrska I., Shintani T., and Klionsky D.J. The actin cytoskeleton is required for selective types of autophagy, but not nonspecific autophagy, in the yeast Saccharomyces cerevisiae. Mol. Biol. Cell 16 (2005) 5843-5856
30. Miura F., Kawaguchi N., Sese J., Toyoda A., Hattori M., Morishita S., and Ito T. A large-scale full-length cDNA analysis to explore the budding yeast transcriptome. Proc. Natl. Acad. Sci. USA 103 (2006) 17846-17851