Modular control analysis of effects of chronic hypoxia on mouse heart

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 295, Issue 6, 2008, Pages

  Calmettes, Guillaume ^a   Deschodt Arsac, Véronique ^a   Thiaudière, Eric ^a   Muller, Bernard ^b   Diolez, Philippe ^a  

^a CNRS University Bordeaux Segalen   (France)

^b CENTRE DE RECHERCHE CARDIO THORACIQUE DE BORDEAUX   (France)

Author keywords

31P labeled magnetic resonance spectroscopy; Perfused mouse heart; Systems biology

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELASTICITY; ENERGY METABOLISM; ENERGY TRANSFER; FEMALE; HEART MITOCHONDRION; HEART MUSCLE CONTRACTILITY; HEART PERFUSION; HYPOXIA; METABOLIC REGULATION; MOUSE; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; REGULATORY MECHANISM;

EID: 57749091789     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.90548.2008     Document Type: Article

References (41)

1. Arsac LM, Beuste C, Miraux S, Deschodt-Arsac V, Thiaudiere E, Franconi JM, Diolez PH. In vivo modular control analysis of energy metabolism in contracting skeletal muscle. Biochem J 414: 391-397, 2008.
2. Balaban RS. Cardiac energy metabolism homeostasis: role of cytosolic calcium. J Mol Cell Cardiol 34: 1259-1271, 2002.
3. Balaban RS, Bose S, French SA, Territo PR. Role of calcium in metabolic signaling between cardiac sarcoplasmic reticulum and mitochondria in vitro. Am J Physiol Cell Physiol 284: C285-C293, 2003.
4. Bers DM. Cardiac excitation-contraction coupling. Nature 415: 198-205, 2002.
5. Brand MD. Top down metabolic control analysis. J Theor Biol 182: 351-360, 1996.
6. Brand MD, Curtis RK. Simplifying metabolic complexity. Biochem Soc Trans 30: 25-30, 2002.
7. Brdiczka D, Beutner G, Ruck A, Dolder M, Wallimann T. The molecular structure of mitochondrial contact sites. Their role in regulation of energy metabolism and permeability transition. Biofactors 8: 235-242, 1998.
8. Brown GC, Hafner RP, Brand MD. A "top-down" approach to the determination of control coefficients in metabolic control theory. Eur J Biochem 188: 321-325, 1990.
9. Casey TM, Pakay JL, Guppy M, Arthur PG. Hypoxia causes down-regulation of protein and RNA synthesis in noncontracting mammalian cardiomyocytes. Circ Res 90: 777-783, 2002.
10. Cazorla O, Ait Mou Y, Goret L, Vassort G, Dauzat M, Lacampagne A, Tanguy S, Obert P. Effects of high-altitude exercise training on contractile function of rat skinned cardiomyocyte. Cardiovasc Res 71: 652-660, 2006.
11. Chatham J, Gilbert HF, Radda GK. Inhibition of glucose phosphorylation by fatty acids in the perfused rat heart. FEBS Lett 238: 445-449, 1988.
12. Clyne CA, Alpert JS, Benotti JR. Interdependence of the left and right ventricles in health and disease. Am Heart J 117: 1366-1373, 1989.
13. Daneshrad Z, Garcia-Riera MP, Verdys M, Rossi A. Differential responses to chronic hypoxia and dietary restriction of aerobic capacity and enzyme levels in the rat myocardium. Mol Cell Biochem 210: 159-166, 2000.
14. Daneshrad Z, Novel-Chate V, Birot O, Serrurier B, Sanchez H, Bigard AX, Rossi A. Diet restriction plays an important role in the alterations of heart mitochondrial function following exposure of young rats to chronic hypoxia. Pflügers Arch 442: 12-18, 2001.
15. Delbridge LM, Connell PJ, Morgan TO, Harris PJ. Contractile function of cardiomyocytes from the spontaneously hypertensive rat. J Mol Cell Cardiol 28: 723-733, 1996.
16. Diolez P, Raffard G, Simon C, Leducq N, Dos SP, Canioni P. Mitochondria do not control heart bioenergetics. Mol Biol Rep 29: 193-196, 2002.
17. Diolez P, Deschodt-Arsac V, Raffard G, Simon C, Santos PD, Thiaudiere E, Arsac L, Franconi JM. Modular regulation analysis of heart contraction: application to in situ demonstration of a direct mitochondrial activation by calcium in beating heart. Am J Physiol Regul Integr Comp Physiol 293: R13-R19, 2007.
18. Dos Santos P, Aliev MK, Diolez P, Duclos F, Besse P, Bonoron-Adele S, Sikk P, Canioni P, Saks VA. Metabolic control of contractile performance in isolated perfused rat heart. Analysis of experimental data by reaction:diffusion mathematical model. J Mol Cell Cardiol 32: 1703-1734, 2000.
19. Epstein FH. MR in mouse models of cardiac disease. NMR Biomed 20: 238-255, 2007.
20. Essop MF. Cardiac metabolic adaptations in response to chronic hypoxia. J Physiol 584: 715-726, 2007.
21. Falk JA, Kadiev S, Criner GJ, Scharf SM, Minai OA, Diaz P. Cardiac disease in chronic obstructive pulmonary disease. Proc Am Thorac Soc 5: 543-548, 2008.
22. Han MK, McLaughlin VV, Criner GJ, Martinez FJ. Pulmonary diseases and the heart. Circulation 116: 2992-3005, 2007.
23. 31P magnetic resonance spectroscopy of the Sherpa heart: a phosphocreatine/adenosine triphosphate signature of metabolic defense against hypobaric hypoxia. Proc Natl Acad Sci USA 93: 1215-1220, 1996.
24. Hoerter J, Gonzalez-Barroso MD, Couplan E, Mateo P, Gelly C, Cassard-Doulcier AM, Diolez P, Bouillaud F. Mitochondrial uncoupling protein 1 expressed in the heart of transgenic mice protects against ischemic-reperfusion damage. Circulation 110: 528-533, 2004.
25. Holden JE, Stone CK, Clark CM, Brown WD, Nickles RJ, Stanley C, Hochachka PW. Enhanced cardiac metabolism of plasma glucose in high-altitude natives: adaptation against chronic hypoxia. J Appl Physiol 79: 222-228, 1995.
26. Kacser H, Burns JA. The control of flux. Symp Soc Exp Biol 27: 65-104, 1973.
27. Korzeniewski B, Deschodt-Arsac V, Calmettes G, Franconi JM, Diolez PH. Physiological heart activation by adrenaline involves parallel activation of ATP usage and supply. Biochem J 413: 343-347, 2008.
28. Leverve X. Metabolic and nutritional consequences of chronic hypoxia. Clin Nutr 17: 241-251, 1998.
29. Nouette-Gaulain K, Malgat M, Rocher C, Savineau JP, Marthan R, Mazat JP, Sztark F. Time course of differential mitochondrial energy metabolism adaptation to chronic hypoxia in right and left ventricles. Cardiovasc Res 66: 132-140, 2005.
30. Novel-Chate V, Aussedat J, Saks VA, Rossi A. Adaptation to chronic hypoxia alters cardiac metabolic response to beta stimulation: novel face of phosphocreatine overshoot phenomenon. J Mol Cell Cardiol 27: 1679-1687, 1995.
31. Novel-Chate V, Mateo P, Saks VA, Hoerter JA, Rossi A. Chronic exposure of rats to hypoxic environment alters the mechanism of energy transfer in myocardium. J Mol Cell Cardiol 30: 1295-1303, 1998.
32. Omerovic E, Basetti M, Bollano E, Bohlooly YM, Tornell J, Isgaard J, Hjalmarson A, Soussi B, Waagstein F. In vivo metabolic imaging of cardiac bioenergetics in transgenic mice. Biochem Biophys Res Commun 271: 222-228, 2000.
33. Ostadal B, Kolar F. Cardiac adaptation to chronic high-altitude hypoxia: beneficial and adverse effects. Respir Physiol Neurobiol 158: 224-236, 2007.
34. Pei JM, Kravtsov GM, Wu S, Das R, Fung ML, Wong TM. Calcium homeostasis in rat cardiomyocytes during chronic hypoxia: a time course study. Am J Physiol Cell Physiol 285: C1420-C1428, 2003.
35. Pissarek M, Bigard X, Mateo P, Guezennec CY, Hoerter JA. Adaptation of cardiac myosin and creatine kinase to chronic hypoxia: role of anorexia and hypertension. Am J Physiol Heart Circ Physiol 272: H1690-H1695, 1997.
36. Razeghi P, Young ME, Abbasi S, Taegtmeyer H. Hypoxia in vivo decreases peroxisome proliferator-activated receptor alpha-regulated gene expression in rat heart. Biochem Biophys Res Commun 287: 5-10, 2001.
37. Rumsey WL, Abbott B, Bertelsen D, Mallamaci M, Hagan K, Nelson D, Erecinska M. Adaptation to hypoxia alters energy metabolism in rat heart. Am J Physiol Heart Circ Physiol 276: H71-H80, 1999.
38. Schlattner U, Dolder M, Wallimann T, Tokarska-Schlattner M. Mitochondrial creatine kinase and mitochondrial outer membrane porin show a direct interaction that is modulated by calcium. J Biol Chem 276: 48027-48030, 2001.
39. Silverman HS, Wei S, Haigney MC, Ocampo CJ, Stern MD. Myocyte adaptation to chronic hypoxia and development of tolerance to subsequent acute severe hypoxia. Circ Res 80: 699-707, 1997.
40. Ten Hove M, Neubauer S. MR spectroscopy in heart failure - clinical and experimental findings. Heart Fail Rev 12: 48-57, 2007.
41. Weiss JN, Yang L, Qu Z. Systems biology approaches to metabolic and cardiovascular disorders: network perspectives of cardiovascular metabolism. J Lipid Res 47: 2355-2366, 2006.