Mechanism of CNS drugs and their combinations for Alzheimer's disease

Central Nervous System Agents in Medicinal Chemistry

Volumn 8, Issue 4, 2008, Pages 241-248

  Keowkase, Roongpetch ^a   Luo, Yuan ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

Author keywords

Alzheimer's disease; Combination therapy; Ginkgo biloba

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; BILOBALIDE; BUNGAROTOXIN RECEPTOR; CHOLINESTERASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DIZOCILPINE; DONEPEZIL; FLUOXETINE; GALANTAMINE; GINKGO BILOBA EXTRACT; GINKGOLIDE A; GINKGOLIDE B; GINKGOLIDE C; GINKGOLIDE J; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PLACEBO; RIVASTIGMINE; TACRINE; TRICYCLIC ANTIDEPRESSANT AGENT;

ALZHEIMER DISEASE; BRAIN REGION; BRAIN SLICE; CAENORHABDITIS ELEGANS; CLINICAL TRIAL; COGNITIVE DEFECT; CONCENTRATION RESPONSE; CONSTIPATION; DAILY LIFE ACTIVITY; DEPRESSION; DIARRHEA; DIZZINESS; DRUG EFFICACY; DRUG HYPERSENSITIVITY; DRUG MECHANISM; DRUG POTENTIATION; DRUG RECEPTOR BINDING; FOOD AND DRUG ADMINISTRATION; FOREBRAIN; GASTROINTESTINAL SYMPTOM; GINKGO BILOBA; GRANULE CELL; HEADACHE; HIPPOCAMPUS; HUMAN; IN VITRO STUDY; LIVER FUNCTION; LIVER INJURY; LONG TERM POTENTIATION; LOW DRUG DOSE; MAZE TEST; MULTIINFARCT DEMENTIA; NAUSEA; NERVE CELL CULTURE; NERVOUS SYSTEM DEVELOPMENT; NEUROPHARMACOLOGY; NEUROPROTECTION; NONHUMAN; OLIGOMERIZATION; OXIDATIVE STRESS; PLANT LEAF; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; REVIEW; SENILE DEMENTIA; SIDE EFFECT; SKIN MANIFESTATION; SLEEP DISORDER; THERAPY EFFECT; TREATMENT RESPONSE; VOMITING; XEROSTOMIA;

EID: 57749089428     PISSN: 18715249     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152408786848166     Document Type: Review

References (82)

1. Blennow, K.; Leon, M.J.; Zetterberg, H. Lancet, 2006, 368, 387-403.
2. Terry, A.; Buccafusco, J. J. Pharmacol. Exp. Ther., 2003, 306, 821-827.
3. Giacobini, E. CNS Drugs, 2001, 15, 85-91.
4. Racchi, M.; Mazzucchelli, M.; Porrello, E.; Lanni, C.; Govoni, S. Pharmacol. Res., 2004, 50, 441-451.
5. Racchi, M.; Govoni, S. Trends Pharmacol. Sci., 1999, 20, 418-423.
6. Wagstaff, A.; McTavish, D. Drugs Aging, 1994, 4, 510-540.
7. Dooley, M.; Lamb, H. Drugs Aging, 2000, 16, 199-226.
8. Van Dam, D.; Coen, K.; De Deyn, P.P. Psychopharmacology, 2008, 197, 37-43
9. Moriguchi, S.; Zhao, X.; Marszalec, W.; Yeh, J.Z.; Narahashi, T. J. Pharmacol. Exp. Ther., 2005, 315, 125-135.
10. Takada, Y.; Yonezawa, A.; Kume, T.; Katsuki, H.; Kaneko, S.; Sugimoto, H.; Akaike, A. J. Pharmacol. Exp. Ther., 2003, 306, 772-777.
11. Kume, T.; Sugimoto, M.; Takada, Y.; Yamagushi, T.; Yonezawa, A.; Katsuki, H.; Sugimoto, H.; Akaike, A. Eur. J. .Pharmacol., 2005, 527, 77-85.
12. Ohara, T.; Tanaka, K.-i.; Fukaya, H. Jpn. J. Pharmacol., 1996, 71, 98.
13. Spencer, C.; Noble, S. Drugs Aging, 1998, 13, 391-411.
14. Lilienfeld, S. CNS Drug Rev., 2002, 8, 159-176.
15. Lenzken, S.C.; Lanni, C.; Govoni, S.; Lucchelli, A.; Schettini, G.; Racchi, M. Chem. Biol. Interact., 2007, 165, 138-145.
16. Moriguchi, S.; Marszalec, W.; Zhao, X.; Yeh, J.Z.; Narahashi, T. J. Pharmacol. Exp. Ther., 2004, 310, 933-942.
17. Takada, Y.; Kume, T.; Sugimoto, M.; Katsuki, H.; Niidome, T.; Sugimoto, H.; Fujii, T.; Okabe, S.; Akaike, A. Eur. J. Pharmacol., 2006, 549, 19-26.
18. Geerts, H. Brain Res. Bull., 2005, 64, 519-524.
19. Cacabelos, R.; Takeda, M.; Winblad, B. Int. J. Geriatr. Psychiatry, 1999, 14, 3-47.
20. Lipton, S.A. Curr. Alzheimer Res., 2005, 2, 155-65.
21. Robinson, D.M.; Keating, G.M. Drugs, 2006, 66, 1515-34.
22. Parsons, C.G.; Stoffler, A.; Danysz, W. Neuropharmacology, 2007, 53, 699-723.
23. Wilcock, G.K. Lancet Neurol., 2003, 2, 503-505.
24. Volbracht, C.; Beek, J.v.; Zhu, C.; Blomgren, K.; Leist, M. Eur. J. Neurosci., 2006, 23, 2611-2622.
25. Miguel-Hidalgo, J.; Alvarez, X.; Cacabelos, R.; Quack, G. Brain Res., 2002, 958, 210-221.
26. Nakamura, S.; Murayama, N.; Noshita, T.; Katsuragi, R.; Ohno, T. Eur. J. Pharmacol., 2006, 548, 115-122.
27. Minkeviciene, R.; Banerjee, P.; Tanila, H. J. Pharmacol. Exp. Ther., 2004, 311, 677-682.
28. Aracava, Y.; Pereira, E.F.; Maelicke, A.; X, A.E. J. Pharmacol. Exp. Ther., 2005, 312, 1195-1205.
29. Smith, J.V.; Luo, Y. Appl. Microbiol. Biotechnol., 2004, 64, 465-72.
30. Yao, Z.-X.; Drieu, K.; Papadopoulos, V. Brain Res., 2001, 889, 181-190.
31. Luo, Y.; Smith, J.V.; Paramasivam, V.; Burdick, A.; Curry, K.J.; Buford, J.P. Proc. Natl. Acad. Sci. USA, 2002, 99, 12197-12202.
32. Bastianetto, S.; Ramassamy, C.; Dore, S.; Christen, Y.; Poirier, J.; Quirion, R. Eur. J. Neurosci., 2000, 12, 1882-1890.
33. Eckert, A.; Keil, U.; Scherping, I.; Hauptmann, S.; Muller, W. Ann. N. Y. Acad. Sci., 2005, 1056, 474-85.
34. Eckert, A.; Keil, U.; Kressmann, S.; Schindowski, K.; Leutner, S.; Leutz, S.; Muller, W. Pharmacopsychiatry, 2003, 36, S15-23.
35. Bastianetto, S.; Zheng, W.-H.; Quirion, R. J. Neurochem., 2000, 74, 2268-2277.
36. Bate, C.; Tayebi, M.; Williams, A. Mol. Neurodegener., 2008, 3, 1.
37. Ahlemeyer, B.; Krieglstein, J. Pharmacopsychiatry, 2003, 36, 8-14.
38. Ahlemeyer, B.; Mowes, A.; Krieglstein, J. Eur. J. Pharmacol., 1999, 367, 423-30.
39. Strange, K. Meth. Mol. Biol., 2006, 351, 1-11.
40. Link, C.D. Exp. Gerontol., 2006, 41, 1007-13.
41. Link, C.D. Proc. Natl. Acad. Sci. USA, 1995, 92, 9368-72.
42. Crouch, P.J.; Harding, S.-M.E.; White, A.R.; Camakaris, J.; Bush, A.I.; Masters, C.L. Int. J. Biochem. Cell Biol., 2008, 40, 181-198.
43. Smith, J.V.; Luo, Y. J. Alzheimers Dis., 2003, 5, 287-300.
44. Kampkotter, A.; Pielarski, T.; Rohrig, R.; Timpel, C.; Chovolou, Y.; Watjen, W.; Kahl, R. Pharmacol. Res., 2007, 55, 139-147.
45. Wu, Y.; Smith, J.V.; Paramasivam, V.; Butko, P.; Khan, I.; Cypser, J.; Luo, Y. Cell Mol. Biol., (Noisy-le-grand), 2002, 48, 725-31.
46. Wu, Y.; Wu, Z.; Butko, P.; Christen, Y.; Lambert, M.P.; Klein, W.L.; Link, C.D.; Luo, Y. J. Neurosci., 2006, 26, 13102-13.
47. Strayer, A.; Wu, Z.; Christen, Y.; Link, C.D.; Luo, Y. FASEB J., 2003, 17, 2305-2307.
48. Tong, L.; Thornton, P.L.; Balazs, R.; Cotman, C.W. J. Biol. Chem., 2001, 276, 17301-17306.
49. Tchantchou, F.; Xu, Y.; Wu, Y.; Christen, Y.; Luo, Y. FASEB J., 2007, 21, 2400-8.
50. Cohen-salmon, C.; Venault, P.; Martin, B.; Raffalli-Sebille, M.-J.; Barkats, M.; Clostre, F.; Pardon, M.-C.; Christen, Y.; Chapouthier, G. J. Physiol. (Paris), 1997, 91, 291-300.
51. Williams, B.; Watanabe, C.M.; Schultz, P.G.; Rimbach, G.; Krucker, T. Neurobiol. Aging, 2004, 25, 955-962.
52. Stoll, S.; Scheuer, K.; Pohl, O.; Muller, W. Pharmacopsychiatry, 1996, 29, 144-149.
53. Stackman, R.W.; Eckenstein, F.; Frei, B.; Kulhanek, D.; Nowlin, J.; Quinn, J. Exp. Neurol., 2003, 184, 510-520.
54. Huguet, F.; Drieu, K.; Piriou, A. J. Pharm. Pharmacol., 1994, 46, 316-318.
55. Ramassamy, C.; Christen, Y.; Clostre, F.; Costentin, J. J. Pharm. Pharmacol., 1992, 44, 943-5.
56. Sakakibara, H.; Ishida, K.; Grundmann, O.; Nakajima, J.-i.; Seo, S.; Butterweck, V.; Minami, Y.; Saito, S.; Kawai, Y.; Nakaya, Y.; Terao, J. Biol. Pharm. Bull., 2006, 29, 1767-1770.
57. Vitolo, O.; Gong, B.; Cao, Z.; Ishii, H.; Jaracz, S.; Nakanishi, K.; Arancio, O.; Dzyuba, S.V.; Lefort, R.; Shelanski, M. Neurobiol. Aging, 2007.
58. Chandrasekaran, K.; Mehrabian, Z.; Spinnewyn, B.; Chinopoulos, C.; Drieu, K.; Fiskum, G. Pharmacopsychiatry, 2003, 36, 89-94.
59. Wang, S.-J.; Chen, H.-H. Eur. J. Pharmacol., 2005, 514, 141-149.
60. Le Bars, P.; Katz, M.; Berman, N.; Itil, T.; Freedman, A.; Schatzberg, A. JAMA, 1997, 278.
61. Mix, J.A.; Crew, D.W. Hum. Psychopharmacol. Clin. Exp., 2002, 17, 267-277.
62. Solomon, P.R.; Adam, F.; Silver, A.; Zimmer, J.; DeVeaux, R. JAMA, 2002, 288, 835-840.
63. Carlson, J.J.; Farquhar, J.W.; DiNucci, E.; Ausserer, L.; Zehnder, J.; Miller, D.; Berra, K.; Hagerty, L.; Haskell, W.L. J. Am. Diet Assoc., 2007, 107, 422-432.
64. Birks, J.; Grimley, E.J. Cochrane Database Syst. Rev., 2002, 4, CD003120.
65. Mazza, M.; Capuano, A.; Bria, P.; Mazza, S. Eur. J. Neurol., 2006, 13, 981-985.
66. DeKosky, S.T.; Fitzpatrick, A.; Ives, D.G.; Saxton, J.; Williamson, J.; Lopez, O.L.; Burke, G.; Fried, L.; Kuller, L.H.; Robbins, J.; Tracy, R.; Woolard, N.; Dunn, L.; Kronmal, R.; Nahin, R.; Furberg, C. Contemp. Clin. Trials, 2006, 27, 238-53.
67. Vellas, B.; Andrieu, S.; Ousset, P.; Ouzid, M.; Mathiex-Fortunet, H. Neurology, 2006, 67, S6-S11.
68. Dodge, H.; Zitzelberger, T.; Oken, B.; Howieson, D.; Kaye, J. Neurology, 2008, 70, 1809-17.
69. Xiong, G.; Doraiswamy, P.M. Geriatrics, 2005, 60, 22-6.
70. Wenk, G.L.; Quack, G.; Moebius, H.-J.; Danysz, W. Life Sci., 2000, 66, 1079-1083.
71. Zhao, X.; Marszalec, W.; Toth, P.T.; Huang, J.; Yeh, J.Z.; Narahashi, T. Neuropharmacology, 2006, 51, 1181-1191.
72. Enz, A.; Gentsch, C. Neuropharmacology, 2004, 47, 408-413.
73. Yamada, K.; Takayanagi, M.; Kamei, H.; Nagai, T.; Dohniwa, M.; Kobayashi, K.; Yoshida, S.; Ohhara, T.; Takauma, K.; Nabeshima, T. Behav. Brain Res., 2005, 162, 191-199.
74. Woodruff-Pak, D.S.; Tobia, M.J.; Jiao, X.; Beck, K.D.; Servatius, R.J. Neuropsychopharmacology, 2007, 32, 1284-1294.
75. Rodriguez, G.; Copello, F.; Vitali, P.; Perego, G.; Nobili, F. Clin. Neurophysiol., 1999, 110, 1831-1837.
76. Dringerberg, H.; Diavolitsis, P. Neuropharmacology, 2002, 42, 154-161.
77. Creeley, C.E.; Wozniak, D.F.; Nardi, A.; Farber, N.B.; Olney, J.W. Neurobiol. Aging, 2008, 29, 153-167.
78. Tariot, P.N.; Farlow, M.R.; Grossberg, G.T.; Graham, S.M.; McDonald, S.; Gergel, I. JAMA, 2004, 291, 317-324.
79. Dantoine, T.; Auriacombe, S.; Sarazin, M.; Becker, H.; Pere, J.-J.; Bourdeix, I. Int. J. Clin. Pract., 2006, 60, 110-118.
80. Yasui-Furukori, N.; Furukori, H.; Kaneda, A.; Kanebo, S.; Tateishi, T. J. Clin. Pharmacol., 2004, 44, 538-542.
81. DeFeudis, F. Ginkgo biloba extract (EGb 761): from chemistry to clinic, Publi Ullstein Med: Weisbaden, 1998.
82. Albrecht, D.; Van Ackern, K.; Bender, H.; Hof, H.; Kox, W.; Victor, N.; Funk, P.; Kieser, M.; Kohler, S.; Krausch, D.; Marzi, I.; Menges, T.; Schmidt, H. Clin. Drug Investig., 2004, 24, 137-147.