-
1
-
-
0344688198
-
Galantamine prevents apoptosis induced by β-amyloid and thapsigargin: Involvement of nicotinic acetylcholine receptors
-
E. Arias, E. Alés, N. Gabilan, M. Cano-Abad, M. Villarroya, A. García, and M.G. López Galantamine prevents apoptosis induced by β-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors Neuropharmacology 46 2004 103 114
-
(2004)
Neuropharmacology
, vol.46
, pp. 103-114
-
-
Arias, E.1
Alés, E.2
Gabilan, N.3
Cano-Abad, M.4
Villarroya, M.5
García, A.6
López, M.G.7
-
2
-
-
0030626839
-
Protocols to demonstrate slowing of Alzheimer disease progression. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines. the Disease Progression Sub-Group
-
N. Bodick, F. Forette, D. Hadler, R.J. Harvey, P. Leber, I.G. McKeith, P.J. Riekkinen, M.N. Rossor, P. Scheltens, S. Shimohama, R. Spiegel, S. Tanaka, L.J. Thal, Y. Urata, P. Whitehouse, and G. Wilcock Protocols to demonstrate slowing of Alzheimer disease progression. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines. The Disease Progression Sub-Group Alzheimer Dis. Assoc. Disord. 11 Suppl. 3 1997 50 53
-
(1997)
Alzheimer Dis. Assoc. Disord.
, vol.11
, Issue.3
, pp. 50-53
-
-
Bodick, N.1
Forette, F.2
Hadler, D.3
Harvey, R.J.4
Leber, P.5
McKeith, I.G.6
Riekkinen, P.J.7
Rossor, M.N.8
Scheltens, P.9
Shimohama, S.10
Spiegel, R.11
Tanaka, S.12
Thal, L.J.13
Urata, Y.14
Whitehouse, P.15
Wilcock, G.16
-
3
-
-
12644273785
-
Pharmacological evaluation of novel Alzheimer's disease therapeutics: Acetylcholinesterase inhibitors related to galantamine
-
G.M. Bores, F.P. Huger, and W. Petko Pharmacological evaluation of novel Alzheimer's disease therapeutics: acetylcholinesterase inhibitors related to galantamine J. Pharmacol. Exp. Ther. 277 1996 728 738
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.277
, pp. 728-738
-
-
Bores, G.M.1
Huger, F.P.2
Petko, W.3
-
4
-
-
0034612256
-
Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice
-
S. Capsoni, G. Ugolini, A. Comparini, F. Ruberti, N. Berardi, and A. Cattaneo Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice Proc. Natl. Acad. Sci. 97 12 2000 6826 6831
-
(2000)
Proc. Natl. Acad. Sci.
, vol.97
, Issue.12
, pp. 6826-6831
-
-
Capsoni, S.1
Ugolini, G.2
Comparini, A.3
Ruberti, F.4
Berardi, N.5
Cattaneo, A.6
-
5
-
-
0037125974
-
Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice
-
S. Capsoni, S. Giannotta, and A. Cattaneo Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice Proc. Natl. Acad. Sci. 99 19 2002 12432 12437
-
(2002)
Proc. Natl. Acad. Sci.
, vol.99
, Issue.19
, pp. 12432-12437
-
-
Capsoni, S.1
Giannotta, S.2
Cattaneo, A.3
-
6
-
-
0035896466
-
Differential increase in cerebrospinal fluid-acetylcholinesterase after treatment with acetylcholinesterase inhibitors in patients with Alzheimer's disease
-
P. Davidsson, K. Blennow, N. Andreasen, B. Eriksson, L. Minthon, and C. Hesse Differential increase in cerebrospinal fluid-acetylcholinesterase after treatment with acetylcholinesterase inhibitors in patients with Alzheimer's disease Neurosci. Lett. 300 3 2001 157 160
-
(2001)
Neurosci. Lett.
, vol.300
, Issue.3
, pp. 157-160
-
-
Davidsson, P.1
Blennow, K.2
Andreasen, N.3
Eriksson, B.4
Minthon, L.5
Hesse, C.6
-
7
-
-
0011162190
-
Selective loss of central cholinergic neurons in Alzheimer's disease
-
P. Davies, and A.J. Maloney Selective loss of central cholinergic neurons in Alzheimer's disease Lancet 2 1976 1403
-
(1976)
Lancet
, vol.2
, pp. 1403
-
-
Davies, P.1
Maloney, A.J.2
-
8
-
-
0033591017
-
Cholinergic markers in elderly patients with early signs of Alzheimer disease
-
K.L. Davis, R.C. Mohs, D. Marin, D.P. Purohit, D.P. Perl, M. Lantz, G. Austin, and V. Haroutunian Cholinergic markers in elderly patients with early signs of Alzheimer disease JAMA 281 15 1999 1401 1406
-
(1999)
JAMA
, vol.281
, Issue.15
, pp. 1401-1406
-
-
Davis, K.L.1
Mohs, R.C.2
Marin, D.3
Purohit, D.P.4
Perl, D.P.5
Lantz, M.6
Austin, G.7
Haroutunian, V.8
-
9
-
-
0642340251
-
M1 muscarinic agonists can modulate some of the hallmarks in Alzheimer's disease: Implications in future therapy
-
A. Fisher, Z. Pittel, R. Haring, N. Bar-Ner, M. Kliger-Spatz, N. Natan, I. Egozi, H. Sonego, I. Marcovitch, and R. Brandeis M1 muscarinic agonists can modulate some of the hallmarks in Alzheimer's disease: implications in future therapy J. Mol. Neurosci. 20 3 2003 349 356
-
(2003)
J. Mol. Neurosci.
, vol.20
, Issue.3
, pp. 349-356
-
-
Fisher, A.1
Pittel, Z.2
Haring, R.3
Bar-Ner, N.4
Kliger-Spatz, M.5
Natan, N.6
Egozi, I.7
Sonego, H.8
Marcovitch, I.9
Brandeis, R.10
-
10
-
-
11444257171
-
Functional studies of brain level and AChE inhibition with galantamine and donepezil in rats, mice and rabbits
-
H. Geerts, C. Grantham, Guillaumat Pierre-Olivier, Nini Bode, Katelijne Anciaux, and Sachak Sohel Functional studies of brain level and AChE inhibition with galantamine and donepezil in rats, mice and rabbits Neurobiol. Aging 25 S2 2004 187
-
(2004)
Neurobiol. Aging
, vol.25
, Issue.2
, pp. 187
-
-
Geerts, H.1
Grantham, C.2
Pierre-Olivier, G.3
Bode, N.4
Anciaux, K.5
Sohel, S.6
-
11
-
-
1542270719
-
Reduced levels of Abeta 40 and Abeta 42 in brains of smoking controls and Alzheimer's patients
-
E. Hellstrom-Lindahl, M. Mousavi, R. Ravid, and A. Nordberg Reduced levels of Abeta 40 and Abeta 42 in brains of smoking controls and Alzheimer's patients Neurobiol. Dis. 15 2 2004 351 360
-
(2004)
Neurobiol. Dis.
, vol.15
, Issue.2
, pp. 351-360
-
-
Hellstrom-Lindahl, E.1
Mousavi, M.2
Ravid, R.3
Nordberg, A.4
-
12
-
-
12444313989
-
Treatment with the selective muscarinic m1 agonist talsaclidine decreases cerebrospinal fluid levels of Abeta 42 in patients with Alzheimer's disease
-
C. Hock, A. Maddalena, A. Raschig, F. Muller-Spahn, G. Eschweiler, K. Hager, I. Heuser, H. Hampel, T. Muller-Thomsen, W. Oertel, M. Wienrich, A. Signorell, C. Gonzalez-Agosti, and R.M. Nitsch Treatment with the selective muscarinic m1 agonist talsaclidine decreases cerebrospinal fluid levels of Abeta 42 in patients with Alzheimer's disease Amyloid 10 1 2003 1 6
-
(2003)
Amyloid
, vol.10
, Issue.1
, pp. 1-6
-
-
Hock, C.1
Maddalena, A.2
Raschig, A.3
Muller-Spahn, F.4
Eschweiler, G.5
Hager, K.6
Heuser, I.7
Hampel, H.8
Muller-Thomsen, T.9
Oertel, W.10
Wienrich, M.11
Signorell, A.12
Gonzalez-Agosti, C.13
Nitsch, R.M.14
-
13
-
-
0141676771
-
Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury?
-
C. Ikonomidou, and L. Turski Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury? Lancet Neurol. 1 6 2002 383 386
-
(2002)
Lancet Neurol.
, vol.1
, Issue.6
, pp. 383-386
-
-
Ikonomidou, C.1
Turski, L.2
-
14
-
-
19944428324
-
Long-term effects of galantamine treatment on brain cortical acetylcholinesterase inhibition and nicotinic receptors in Alzheimer patients visualized by PET
-
Montreal
-
Ahmadul Kadir, Michaela Grut, Anders Wall, Elka Stefanova, Ove Almkvist, Gunnar Blomqvist, Birgitta Strandberg, Bo Eriksson, Bengt Långström, and Agneta Nordberg Long-term effects of galantamine treatment on brain cortical acetylcholinesterase inhibition and nicotinic receptors in Alzheimer patients visualized by PET Springfield Symposium Montreal 2004
-
(2004)
Springfield Symposium
-
-
Ahmadul, K.1
Michaela, G.2
Anders, W.3
Elka, S.4
Ove, A.5
Gunnar, B.6
Birgitta, S.7
Bo, E.8
Bengt, L.9
Agneta, N.10
-
15
-
-
0030756236
-
Nicotinic receptor stimulation protects neurons against β-amyloid toxicity
-
T. Kihara, S. Shimohama, H. Sawada, J. Kimura, T. Kume, H. Kochiyama, T. Maeda, and A. Akaike Nicotinic receptor stimulation protects neurons against β-amyloid toxicity Ann. Neurol. 42 1997 159 163
-
(1997)
Ann. Neurol.
, vol.42
, pp. 159-163
-
-
Kihara, T.1
Shimohama, S.2
Sawada, H.3
Kimura, J.4
Kume, T.5
Kochiyama, H.6
Maeda, T.7
Akaike, A.8
-
16
-
-
0032507506
-
Stimulation of alpha4beta2 nicotinic acetylcholine receptors inhibits beta-amyloid toxicity
-
T. Kihara, S. Shimohama, M. Urushitani, H. Sawada, J. Kimura, T. Kume, T. Maeda, and A. Akaike Stimulation of alpha4beta2 nicotinic acetylcholine receptors inhibits beta-amyloid toxicity Brain Res. 792 1998 331 334
-
(1998)
Brain Res.
, vol.792
, pp. 331-334
-
-
Kihara, T.1
Shimohama, S.2
Urushitani, M.3
Sawada, H.4
Kimura, J.5
Kume, T.6
Maeda, T.7
Akaike, A.8
-
17
-
-
0033844518
-
Limited donepezil inhibition of acetylcholinesterase measured with positron emission tomography in living Alzheimer cerebral cortex
-
D.E. Kuhl, S. Minoshima, K.A. Frey, N.L. Foster, M.R. Kilbourn, and R.A. Koeppe Limited donepezil inhibition of acetylcholinesterase measured with positron emission tomography in living Alzheimer cerebral cortex Ann. Neurol. 48 3 2000 391 395
-
(2000)
Ann. Neurol.
, vol.48
, Issue.3
, pp. 391-395
-
-
Kuhl, D.E.1
Minoshima, S.2
Frey, K.A.3
Foster, N.L.4
Kilbourn, M.R.5
Koeppe, R.A.6
-
18
-
-
1342328037
-
Alcohol and tobacco consumption as risk factors of dementia: A review of epidemiological studies
-
L. Letenneur, S. Larrieu, and P. Barberger-Gateau Alcohol and tobacco consumption as risk factors of dementia: a review of epidemiological studies Biomed. Pharmacother. 58 2 2004 95 99
-
(2004)
Biomed. Pharmacother.
, vol.58
, Issue.2
, pp. 95-99
-
-
Letenneur, L.1
Larrieu, S.2
Barberger-Gateau, P.3
-
19
-
-
0036316642
-
Chronic nicotine treatment reduces beta-amyloidosis in the brain of a mouse model of Alzheimer's disease (APPsw)
-
A. Nordberg, E. Hellstrom-Lindahl, M. Lee, M. Johnson, M. Mousavi, R. Hall, E. Perry, I. Bednar, and J. Court Chronic nicotine treatment reduces beta-amyloidosis in the brain of a mouse model of Alzheimer's disease (APPsw) J. Neurochem. 81 3 2002 655 658
-
(2002)
J. Neurochem.
, vol.81
, Issue.3
, pp. 655-658
-
-
Nordberg, A.1
Hellstrom-Lindahl, E.2
Lee, M.3
Johnson, M.4
Mousavi, M.5
Hall, R.6
Perry, E.7
Bednar, I.8
Court, J.9
-
20
-
-
3042843491
-
AMPA receptor potentiators for the treatment of CNS disorders
-
M.J. O'Neill, D. Bleakman, D.M. Zimmerman, and E.S. Nisenbaum AMPA receptor potentiators for the treatment of CNS disorders Curr. Drug Targets CNS Neurol. Disord. 3 3 2004 181 194
-
(2004)
Curr. Drug Targets CNS Neurol. Disord.
, vol.3
, Issue.3
, pp. 181-194
-
-
O'Neill, M.J.1
Bleakman, D.2
Zimmerman, D.M.3
Nisenbaum, E.S.4
-
21
-
-
18744417222
-
Cerebrospinal fluid levels of biomarkers and activity of acetylcholinesterase (AChE) and butyrylcholinesterase in AD patients before and after treatment with different AChE inhibitors
-
L. Parnetti, S. Amici, A. Lanari, C. Romani, C. Antognelli, N. Andreasen, L. Minthon, P. Davidsson, H. Pottel, K. Blennow, and V. Gallai Cerebrospinal fluid levels of biomarkers and activity of acetylcholinesterase (AChE) and butyrylcholinesterase in AD patients before and after treatment with different AChE inhibitors Neurol. Sci. 23 Suppl. 2 2002 S95 S96
-
(2002)
Neurol. Sci.
, vol.23
, Issue.2
-
-
Parnetti, L.1
Amici, S.2
Lanari, A.3
Romani, C.4
Antognelli, C.5
Andreasen, N.6
Minthon, L.7
Davidsson, P.8
Pottel, H.9
Blennow, K.10
Gallai, V.11
-
22
-
-
1042291157
-
The cognitive benefits of galantamine are sustained for at least 36 months: A long-term extension trial
-
M.A. Raskind, E.R. Peskind, L. Truyen, P. Kershaw, and C.V. Damaraju The cognitive benefits of galantamine are sustained for at least 36 months: a long-term extension trial Arch. Neurol. 61 2 2004 252 256
-
(2004)
Arch. Neurol.
, vol.61
, Issue.2
, pp. 252-256
-
-
Raskind, M.A.1
Peskind, E.R.2
Truyen, L.3
Kershaw, P.4
Damaraju, C.V.5
-
23
-
-
10744232323
-
Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors
-
M. Samochocki, A. Hoffle, A. Fehrenbacher, R. Jostock, J. Ludwig, C. Christner, M. Radina, M. Zerlin, C. Ullmer, E.F. Pereira, H. Lubbert, E.X. Albuquerque, and A. Maelicke Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors J. Pharmacol. Exp. Ther. 305 3 2003 1024 1036
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.305
, Issue.3
, pp. 1024-1036
-
-
Samochocki, M.1
Hoffle, A.2
Fehrenbacher, A.3
Jostock, R.4
Ludwig, J.5
Christner, C.6
Radina, M.7
Zerlin, M.8
Ullmer, C.9
Pereira, E.F.10
Lubbert, H.11
Albuquerque, E.X.12
Maelicke, A.13
-
24
-
-
0036232874
-
The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system
-
M.D. Santos, M. Alkondon, and E.F. Pereira The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system Mol. Pharmacol. 61 2002 1222 1234
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 1222-1234
-
-
Santos, M.D.1
Alkondon, M.2
Pereira, E.F.3
-
25
-
-
0035852825
-
Effect of donepezil on brain acetylcholinesterase activity in patients with AD measured by PET
-
H. Shinotoh, A. Aotsuka, K. Fukushi, S. Nagatsuka, N. Tanaka, T. Ota, S. Tanada, and T. Irie Effect of donepezil on brain acetylcholinesterase activity in patients with AD measured by PET Neurology 56 3 2001 408 410
-
(2001)
Neurology
, vol.56
, Issue.3
, pp. 408-410
-
-
Shinotoh, H.1
Aotsuka, A.2
Fukushi, K.3
Nagatsuka, S.4
Tanaka, N.5
Ota, T.6
Tanada, S.7
Irie, T.8
-
26
-
-
2942560510
-
Proteins released from degenerating neurons are surrogate markers for acute brain damage
-
R. Siman, T.K. McIntosh, K.M. Soltesz, Z. Chen, R.W. Neumar, and V.L. Roberts Proteins released from degenerating neurons are surrogate markers for acute brain damage Neurobiol. Dis. 16 2 2004 311 320
-
(2004)
Neurobiol. Dis.
, vol.16
, Issue.2
, pp. 311-320
-
-
Siman, R.1
McIntosh, T.K.2
Soltesz, K.M.3
Chen, Z.4
Neumar, R.W.5
Roberts, V.L.6
-
27
-
-
3042732149
-
Galantamine and memantine produce different degrees of neuroprotection in rat hippocampal slices subjected to oxygen-glucose deprivation
-
M. Sobrado, J.M. Roda, M.G. Lopez, J. Egea, and A.G. Garcia Galantamine and memantine produce different degrees of neuroprotection in rat hippocampal slices subjected to oxygen-glucose deprivation Neurosci. Lett. 365 2 2004 132 136
-
(2004)
Neurosci. Lett.
, vol.365
, Issue.2
, pp. 132-136
-
-
Sobrado, M.1
Roda, J.M.2
Lopez, M.G.3
Egea, J.4
Garcia, A.G.5
-
28
-
-
0028262405
-
A longitudinal study of Alzheimer's disease: Measurement, rate, and predictors of cognitive deterioration
-
R.G. Stern, R.C. Mohs, M. Davidson, J. Schmeidler, J. Silverman, E. Kramer-Ginsberg, T. Searcey, L. Bierer, and K.L. Davis A longitudinal study of Alzheimer's disease: measurement, rate, and predictors of cognitive deterioration Am. J. Psychiatry 151 1994 390 396
-
(1994)
Am. J. Psychiatry
, vol.151
, pp. 390-396
-
-
Stern, R.G.1
Mohs, R.C.2
Davidson, M.3
Schmeidler, J.4
Silverman, J.5
Kramer-Ginsberg, E.6
Searcey, T.7
Bierer, L.8
Davis, K.L.9
-
29
-
-
0037622682
-
Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons
-
Y. Takada, A. Yonezawa, T. Kume, H. Katsuki, S. Kaneko, H. Sugimoto, and A. Akaike Nicotinic acetylcholine receptor-mediated neuroprotection by donepezil against glutamate neurotoxicity in rat cortical neurons J. Pharmacol. Exp. Ther. 306 2 2003 772 777
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.306
, Issue.2
, pp. 772-777
-
-
Takada, Y.1
Yonezawa, A.2
Kume, T.3
Katsuki, H.4
Kaneko, S.5
Sugimoto, H.6
Akaike, A.7
-
30
-
-
0025339542
-
Selective inhibition of human acetylcholinesterase by galanthamine in vitro and in vivo
-
T. Thomsen, and H. Kewitz Selective inhibition of human acetylcholinesterase by galanthamine in vitro and in vivo Life Sci. 46 1990 1553 1558
-
(1990)
Life Sci.
, vol.46
, pp. 1553-1558
-
-
Thomsen, T.1
Kewitz, H.2
-
31
-
-
11444251978
-
Long-term effects of treatment with galantamine on patients with Alzheimer's disease
-
L. Truyen Long-term effects of treatment with galantamine on patients with Alzheimer's disease Res. Pract. Alzheimers Dis. 8 2004 1 4
-
(2004)
Res. Pract. Alzheimers Dis.
, vol.8
, pp. 1-4
-
-
Truyen, L.1
-
32
-
-
0347479327
-
Nerve growth factor: From animal models of cholinergic neuronal degeneration to gene therapy in Alzheimer's disease
-
M.H. Tuszynski, and A. Blesch Nerve growth factor: from animal models of cholinergic neuronal degeneration to gene therapy in Alzheimer's disease Prog. Brain Res. 146 2004 441 449
-
(2004)
Prog. Brain Res.
, vol.146
, pp. 441-449
-
-
Tuszynski, M.H.1
Blesch, A.2
-
33
-
-
0032237793
-
Clinical trial designs for demonstrating disease-course-altering effects in dementia
-
P.J. Whitehouse, B. Kittner, M. Roessner, M. Rossor, M. Sano, L. Thal, and B. Winblad Clinical trial designs for demonstrating disease-course-altering effects in dementia Alzheimer Dis. Assoc. Disord. 12 4 1998 281 294
-
(1998)
Alzheimer Dis. Assoc. Disord.
, vol.12
, Issue.4
, pp. 281-294
-
-
Whitehouse, P.J.1
Kittner, B.2
Roessner, M.3
Rossor, M.4
Sano, M.5
Thal, L.6
Winblad, B.7
|