The opioid receptor antagonist naltrexone attenuates reinstatement of amphetamine drug-seeking in the rat

Behavioural Brain Research

Volumn 197, Issue 1, 2009, Pages 219-224

  Häggkvist, Jenny ^a   Lindholm, Sara ^a,b   Franck, Johan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

Dopamine; Psychostimulant dependence; Relapse; Wistar rat

Indexed keywords

AMPHETAMINE; NALTREXONE; OPIATE ANTAGONIST; SODIUM CHLORIDE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; DRUG ABUSE; DRUG EFFECT; DRUG MECHANISM; INSTRUMENTAL CONDITIONING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REINFORCEMENT;

EID: 57649222034     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2008.08.021     Document Type: Article

References (68)

1. Adams P.M., Beauchamp R., and Alston C. Potentiation of apomorphine and d-amphetamine effects by naloxone. Life Sci 28 (1981) 629-634
2. A.P. American Psychiatric Association. Diagnostic and statistical manual of mental disorders vol. IV (1994), American Psychiatric Association, Washington, DC, USA
3. Amir S., Solomon M., and Amit Z. The effect of acute and chronic naloxone administration on motor activation in the rat. Neuropharmacology 18 (1979) 171-173
4. Anggadiredja K., Sakimura K., Hiranita T., and Yamamoto T. Naltrexone attenuates cue- but not drug-induced methamphetamine seeking: a possible mechanism for the dissociation of primary and secondary reward. Brain Res 1021 (2004) 272
5. Azzaro A.J., and Rutledge C.O. Selectivity of release of norepinephrine, dopamine and 5-hydroxytryptamine by amphetamine in various regions of rat brain. Biochem Pharmacol 22 (1973) 2801-2813
6. Bachteler D., Economidou D., Danysz W., Ciccocioppo R., and Spanagel R. The effects of acamprosate and neramexane on cue-induced reinstatement of ethanol-seeking behavior in rat. Neuropsychopharmacology 30 (2005) 1104-1110
7. Balcells-Olivero M., and Vezina P. Effects of naltrexone on amphetamine-induced locomotion and rearing: acute and repeated injections. Psychopharmacology 131 (1997) 230-238
8. Bosse K.E., Jutkiewicz E.M., Gnegy M.E., and Traynor J.R. The selective delta opioid agonist SNC80 enhances amphetamine-mediated efflux of dopamine from rat striatum. Neuropharmacology 55 (2008) 755-762
9. Brebner K., Ahn S., and Phillips A.G. Attenuation of d-amphetamine self-administration by baclofen in the rat: behavioral and neurochemical correlates. Psychopharmacol (Berl) 177 (2005) 409-417
10. Breiter H.C., Gollub R.L., Weisskoff R.M., Kennedy D.N., Makris N., Berke J.D., et al. Acute effects of cocaine on human brain activity and emotion. Neuron 19 (1997) 591-611
11. Burattini C., Burbassi S., Aicardi G., and Cervo L. Effects of naltrexone on cocaine- and sucrose-seeking behaviour in response to associated stimuli in rats. Int J Neuropsychopharmacol 11 (2008) 103-109
12. Ciccocioppo R., Lin D., Martin-Fardon R., and Weiss F. Reinstatement of ethanol-seeking behavior by drug cues following single versus multiple ethanol intoxication in the rat: effects of naltrexone. Psychopharmacol (Berl) 168 (2003) 208-215
13. Collins S.L., Gerdes R.M., D'Addario C., and Izenwasser S. Kappa opioid agonists alter dopamine markers and cocaine-stimulated locomotor activity. Behav Pharmacol 12 (2001) 237-245
14. Comer S.D., Lac S.T., Curtis L.K., and Carroll M.E. Effects of buprenorphine and naltrexone on reinstatement of cocaine-reinforced responding in rats. J Pharmacol Exp Ther 267 (1993) 1470-1477
15. Corrigall W.A., and Coen K.M. Opiate antagonists reduce cocaine but not nicotine self-administration. Psychopharmacol (Berl) 104 (1991) 167-170
16. de Wit H., and Stewart J. Reinstatement of cocaine-reinforced responding in the rat. Psychopharmacol (Berl) 75 (1981) 134-143
17. DeRossett S.E., and Holtzman S.G. Effects of naloxone and diprenorphine on spontaneous activity in rats and mice. Pharmacol Biochem Behav 17 (1982) 347-351
18. Dettmar P.W., Cowan A., and Walter D.S. Naloxone antagonizes behavioural effects of d-amphetamine in mice and rats. Neuropharmacology 17 (1978) 1041-1044
19. Epstein D.H., Preston K.L., Stewart J., and Shaham Y. Toward a model of drug relapse: an assessment of the validity of the reinstatement procedure. Psychopharmacol (Berl) 189 (2006) 1-16
20. Erb S., Shaham Y., and Stewart J. Stress reinstates cocaine-seeking behavior after prolonged extinction and a drug-free period. Psychopharmacol (Berl) 128 (1996) 408-412
21. Gerrits M.A.F.M., Kuzmin A.V., and van Ree J.M. Reinstatement of cocaine-seeking behavior in rats is attenuated following repeated treatment with the opioid receptor antagonist naltrexone. Eur Neuropsychopharmacol 15 (2005) 297-303
22. Gray A.M., Rawls S.M., Shippenberg T.S., and McGinty J.F. The kappa-opioid agonist, U-69593, decreases acute amphetamine-evoked behaviors and calcium-dependent dialysate levels of dopamine and glutamate in the ventral striatum. J Neurochem 73 (1999) 1066-1074
23. Harrigan S.E., and Downs D.A. Continuous intravenous naltrexone effects on morphine self-administration in rhesus monkeys. J Pharmacol Exp Ther 204 (1978) 481-486
24. Hemby S.E., Smith J.E., and Dworkin S.I. The effects of eticlopride and naltrexone on responding maintained by food, cocaine, heroin and cocaine/heroin combinations in rats. J Pharmacol Exp Ther 277 (1996) 1247-1258
25. Holtzman S.G. Behavioral effects of separate and combined administration of naloxone and d-amphetamine. J Pharmacol Exp Ther 189 (1974) 51-60
26. Hooks M.S., Jones D.N., Justice Jr. J.B., and Holtzman S.G. Naloxone reduces amphetamine-induced stimulation of locomotor activity and in vivo dopamine release in the striatum and nucleus accumbens. Pharmacol Biochem Behav 42 (1992) 765-770
27. Hubner C.B., Bain G.T., and Kornetsky C. The combined effects of morphine and d-amphetamine on the threshold for brain stimulation reward. Pharmacol Biochem Behav 28 (1987) 311-315
28. Jayaram-Lindstrom N., Konstenius M., Eksborg S., Beck O., Hammarberg A., and Franck J. Naltrexone attenuates the subjective effects of amphetamine in patients with amphetamine dependence. Neuropsychopharmacology 33 (2008) 1856-1863
29. Jayaram-Lindstrom N., Wennberg P., Hurd Y.L., and Franck J. Effects of naltrexone on the subjective response to amphetamine in healthy volunteers. J Clin Psychopharmacol 24 (2004) 665-669
30. Jutkiewicz E.M., Baladi M.G., Folk J.E., Rice K.C., and Woods J.H. The delta-opioid receptor agonist SNC80 [(+)-4-[alpha(R)-alpha-[(2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl]-(3-methoxybenzyl)-N,N-diethylbenzamide] synergistically enhances the locomotor-activating effects of some psychomotor stimulants, but not direct dopamine agonists, in rats. J Pharmacol Exp Ther 324 (2008) 714-724
31. Jutkiewicz E.M., Baladi M.G., Folk J.E., Rice K.C., and Woods J.H. The delta-opioid receptor agonist SNC80 synergistically enhances the locomotor-activating effects of some psychomotor stimulants, but not direct dopamine agonists in rats. J Pharmacol Exp Ther JPET 107. (2007) 123844
32. Kalivas P.W., and Stewart J. Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity. Brain Res Rev 16 (1991) 223-244
33. Kimmel H.L., and Holtzman S.G. Mu opioid agonists potentiate amphetamine- and cocaine-induced rotational behavior in the rat. J Pharmacol Exp Ther 282 (1997) 734-746
34. Koob G.F., and Le Moal M. Neurobiology of addiction (2006), Elsevier Inc. p. 490
35. Koob G.F., and Moal M.L. Drug abuse: hedonic homeostatic dysregulation. Science 278 (1997) 52-58
36. Kranzler H.R., Armeli S., Tennen H., Blomqvist O., Oncken C., Petry N., et al. Targeted naltrexone for early problem drinkers. J Clin Psychopharmacol 23 (2003) 294-304
37. Kuczenski R., Segal D.S., Cho A.K., and Melega W. Hippocampus norepinephrine, caudate dopamine and serotonin, and behavioral responses to the stereoisomers of amphetamine and methamphetamine. J Neurosci 15 (1995) 1308-1317
38. Kuzmin A.V., Gerrits M.A., van Ree J.M., and Zvartau E.E. Naloxone inhibits the reinforcing and motivational aspects of cocaine addiction in mice. Life Sci 60 (1997) 257-264
39. Le A.D., Poulos C.X., Harding S., Watchus J., Juzytsch W., and Shaham Y. Effects of naltrexone and fluoxetine on alcohol self-administration and reinstatement of alcohol seeking induced by priming injections of alcohol and exposure to stress. Neuropsychopharmacology 21 (1999) 435-444
40. Leri F., Bruneau J., and Stewart J. Understanding polydrug use: review of heroin and cocaine co-use. Addiction 98 (2003) 7-22
41. Maisonneuve I.M., Archer S., and Glick S.D. U50,488, a kappa opioid receptor agonist, attenuates cocaine-induced increases in extracellular dopamine in the nucleus accumbens of rats. Neurosci Lett 181 (1994) 57-60
42. Meil W.M., and See R.E. Conditioned cued recovery of responding following prolonged withdrawal from self-administered cocaine in rats: an animal model of relapse. Behav Pharmacol 7 (1996) 754-763
43. Melega W.P., Williams A.E., Schmitz D.A., DiStefano E.W., and Cho A.K. Pharmacokinetic and pharmacodynamic analysis of the actions of d-amphetamine and d-methamphetamine on the dopamine terminal. J Pharmacol Exp Ther 274 (1995) 90-96
44. O'Malley S.S., Jaffe A.J., Chang G., Schottenfeld R.S., Meyer R.E., and Rounsaville B. Naltrexone and coping skills therapy for alcohol dependence. A controlled study. Arch Gen Psychiatry 49 (1992) 881-887
45. Olive M.F., Koenig H.N., Nannini M.A., and Hodge C.W. Stimulation of endorphin neurotransmission in the nucleus accumbens by ethanol, cocaine, and amphetamine. J Neurosci 21 (2001) 184RC-
46. Panlilio L.V., and Goldberg S.R. Self-administration of drugs in animals and humans as a model and an investigative tool. Addiction 102 (2007) 1863-1870
47. Pickens R., and Harris W.C. Self-administration of d-amphetamine by rats. Psychopharmacologia 12 (1968) 158-163
48. Ramsey N.F., Gerrits M.A., and Van Ree J.M. Naltrexone affects cocaine self-administration in naive rats through the ventral tegmental area rather than dopaminergic target regions. Eur Neuropsychopharmacol 9 (1999) 93-99
49. Ramsey N.F., and van Ree J.M. Intracerebroventricular naltrexone treatment attenuates acquisition of intravenous cocaine self-administration in rats. Pharmacol Biochem Behav 40 (1991) 807-810
50. Rodgers R.J., and Deacon R.M. Effect of naloxone on the behaviour of rats exposed to a novel environment. Psychopharmacol (Berl) 65 (1979) 103-105
51. Sass H., Soyka M., Mann K., and Zieglgansberger W. Relapse prevention by acamprosate. Results from a placebo-controlled study on alcohol dependence. Arch Gen Psychiatry 53 (1996) 673-680
52. Schad C.A., Justice J.B., and Holtzman S.G. Naloxone reduces the neurochemical and behavioral effects of amphetamine but not those of cocaine. Eur J Pharmacol 275 (1995) 9-16
53. Schad C.A., Justice Jr. J.B., and Holtzman S.G. Differential effects of delta- and mu-opioid receptor antagonists on the amphetamine-induced increase in extracellular dopamine in striatum and nucleus accumbens. J Neurochem 67 (1996) 2292-2299
54. Schad C.A., Justice Jr. J.B., and Holtzman S.G. Endogenous opioids in dopaminergic cell body regions modulate amphetamine-induced increases in extracellular dopamine levels in the terminal regions. J Pharmacol Exp Ther 300 (2002) 932-938
55. Shaham Y., and Stewart J. Stress reinstates heroin-seeking in drug-free animals: an effect mimicking heroin, not withdrawal. Psychopharmacol (Berl) 119 (1995) 334-341
56. Shalev U., Highfield D., Yap J., and Shaham Y. Stress and relapse to drug seeking in rats: studies on the generality of the effect. Psychopharmacol (Berl) 150 (2000) 337-346
57. Shoblock J.R., Sullivan E.B., Maisonneuve I.M., and Glick S.D. Neurochemical and behavioral differences between d-methamphetamine and d-amphetamine in rats. Psychopharmacol (Berl) 165 (2003) 359-369
58. Spealman R.D., and Goldberg S.R. Drug self-administration by laboratory animals: control by schedules of reinforcement. Ann Rev Pharmacol Toxicol 18 (1978) 313-339
59. Srisurapanont M., Jarusuraisin N., and Kittirattanapaiboon P. Treatment for amphetamine dependence and abuse. Cochrane Database Syst Rev (2001) CD003022
60. Tang X.-C., McFarland K., Cagle S., and Kalivas P.W. Cocaine-induced reinstatement requires endogenous stimulation of {micro}-opioid receptors in the ventral pallidum. J Neurosci 25 (2005) 4512-4520
61. Tempesta E., Janiri L., Bignamini A., Chabac S., and Potgieter A. Acamprosate and relapse prevention in the treatment of alcohol dependence: a placebo-controlled study. Alcohol Alcohol 35 (2000) 202-209
62. Trujillo K.A., Belluzzi J.D., and Stein L. Naloxone blockade of amphetamine place preference conditioning. Psychopharmacol (Berl) 104 (1991) 265-274
63. Uwai K., Uchiyama H., Sakurada S., Kabuto C., and Takeshita M. Syntheses and receptor-binding studies of derivatives of the opioid antagonist naltrexone. Bioorg Med Chem 12 (2004) 417-421
64. Waddell A.B., and Holtzman S.G. Modulation of cocaine-induced motor activity in the rat by opioid receptor agonists. Behav Pharmacol 9 (1998) 397-407
65. Walker J.M., Berntson G.G., Paulucci T.S., and Champney T.C. Blockade of endogenous opiates reduces activity in the rat. Pharmacol Biochem Behav 14 (1981) 113-116
66. Weiss F., Maldonado-Vlaar C.S., Parsons L.H., Kerr T.M., Smith D.L., and Ben-Shahar O. Control of cocaine-seeking behavior by drug-associated stimuli in rats: effects on recovery of extinguished operant-responding and extracellular dopamine levels in amygdala and nucleus accumbens. Proc Natl Acad Sci USA 97 (2000) 4321-4326
67. Winslow J.T., and Miczek K.A. Naltrexone blocks amphetamine-induced hyperactivity, but not disruption of social and agonistic behavior in mice and squirrel monkeys. Psychopharmacol (Berl) 96 (1988) 493-499
68. Volpicelli J.R., Alterman A.I., Hayashida M., and O'Brien C.P. Naltrexone in the treatment of alcohol dependence. Arch Gen Psychiatry 49 (1992) 876-880