Allostatic load and frailty in the women's health and aging studies

Biological Research for Nursing

Volumn 10, Issue 3, 2009, Pages 248-256

  Szanton, S L ^a   Allen, J K ^a,b   Seplaki, C L ^a   Bandeen Roche, K ^a   Fried, L P ^a,b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Allostatic load; Frailty; Older adults; Physiologic dysregulation

Indexed keywords

AGED; AGING; ARTICLE; BODY MASS; COHORT ANALYSIS; CROSS-SECTIONAL STUDY; FEMALE; FRAIL ELDERLY; HUMAN; UNITED STATES;

AGED; AGING; BALTIMORE; BODY MASS INDEX; COHORT STUDIES; CROSS-SECTIONAL STUDIES; FEMALE; FRAIL ELDERLY; HUMANS;

EID: 57649159012     PISSN: 10998004     EISSN: 15524175     Source Type: Journal    
DOI: 10.1177/1099800408323452     Document Type: Article

References (41)

1. Bandeen-Roche, K., Xue, Q.L., Ferrucci, L., Walston, J., Guralnik, J.M., Chaves, P., et al. (2006). Phenotype of frailty: Characterization in the women's health and aging studies. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 61, 262-266.
2. Barbieri, M., Ferrucci, L., Ragno, E., Corsi, A., Bandinelli, S., Bonafe, M., et al. (2003). Chronic inflammation and the effect of IGF-I on muscle strength and power in older persons. American Journal of Physiology. Endocrinology and Metabolism, 284, E481 - E487.
3. Bartali, B., Frongillo, E.A., Bandinelli, S., Lauretani, F., Semba, R.D., Fried, L.P., et al. (2006). Low nutrient intake is an essential component of frailty in older persons. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 61, 589-593.
4. Barzilay, J.I., Blaum, C., Moore, T., Xue, Q.L., Hirsch, C.H., Walston, J.D., et al. (2007). Insulin resistance and inflammation as precursors of frailty: The cardiovascular health study. Archives of Internal Medicine, 167, 635-641.
5. Bergman, H., Ferrucci, L., Guralnik, J., Hogan, D.B., Hummel, S., Karunananthan, S., et al. (2007). Frailty: An emerging research and clinical paradigm-issues and controversies. The Journals of Gerontology, Series A, Biological Sciences and Medical Sciences, 62, 731-737.
6. Cappola, A.R., Xue, Q.L., Ferrucci, L., Guralnik, J.M., Volpato, S., & Fried, L.P. (2003). Insulin-like growth factor I and interleukin-6 contribute synergistically to disability and mortality in older women. The Journal of Clinical Endocrinology and Metabolism, 88, 2019-2025.
7. Chaves, P.H., Garrett, E.S., & Fried, L.P. (2000). Predicting the risk of mobility difficulty in older women with screening nomograms: The women's health and aging study II. Archives of Internal Medicine, 160, 2525-2533.
8. Cockcroft, D.W., & Gault, M.H. (1976). Prediction of creatinine clearance from serum creatinine. Nephron, 16, 31-41.
9. Cohen, M.B., & Mather, P.J. (2007). A review of the association between congestive heart failure and cognitive impairment. The American Journal of Geriatric Cardiology, 16, 171-174.
10. Folsom, A.R., Jacobs, D.R., Jr, Caspersen, C.J., Gomez-Marin, O., & Knudsen, J. (1986). Test-retest reliability of the Minnesota leisure time physical activity questionnaire. Journal of Chronic Diseases, 39, 505-511.
11. Fried, L.P., Bandeen-Roche, K., Chaves, P.H., & Johnson, B.A. (2000). Preclinical mobility disability predicts incident mobility disability in older women. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 55, M43 - M52.
12. Fried, L.P., Ferrucci, L., Darer, J., Williamson, J.D., & Anderson, G. (2004). Untangling the concepts of disability, frailty, and comorbidity: Implications for improved targeting and care. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 59, 255-263.
13. Fried, L.P., Tangen, C.M., Walston, J., Newman, A.B., Hirsch, C., Gottdiener, J., et al. (2001). Frailty in older adults: Evidence for a phenotype.. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 56, M146-156.
14. Geronimus, A.T., Hicken, M., Keene, D., & Bound, J. (2006). 'Weathering' and age patterns of allostatic load scores among blacks and whites in the United States. American Journal of Public Health, 96, 826-833.
15. Guralnik, J.M., Fried, L.P., Simonsick, E.M., Kasper, J., & Lafferty, M. (1995). The women's health and aging study: Health and social characteristics of older women with disability. Bethesda, MD: NIH.
16. Hirsch, C., Anderson, M.L., Newman, A., Kop, W., Jackson, S., Gottdiener, J., et al. (2006). The association of race with frailty: The cardiovascular health study. Annals of Epidemiology, 16 (7). 545-553.
17. Holzenberger, M., Dupont, J., Ducos, B., Leneuve, P., Geloen, A., Even, P.C., et al. (2003). IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature, 421, 182-187.
18. Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure. (1997). The sixth report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure. Archives of Internal Medicine, 157, 2413-2446.
19. Karlamangla, A.S., Singer, B.H., McEwen, B.S., Rowe, J.W., & Seeman, T.E. (2002). Allostatic load as a predictor of functional decline. MacArthur studies of successful aging. Journal of Clinical Epidemiology, 55, 696-710.
20. Kimonides, V.G., Khatibi, N.H., Svendsen, C.N., Sofroniew, M.V., & Herbert, J. (1998). Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity. Proceedings of the National Academy of Sciences of the USA, 95, 1852-1857.
21. Kop, W.J., Gottdiener, J.S., Tangen, C.M., Fried, L.P., McBurnie, M.A., Walston, J., et al. (2002). Inflammation and coagulation factors in persons > 65 years of age with symptoms of depression but without evidence of myocardial ischemia. The American Journal of Cardiology, 89, 419-424.
22. Leng, S.X., Xue, Q.L., Tian, J., Walston, J.D., & Fried, L.P. (2007). Inflammation and frailty in older women. Journal of the American Geriatrics Society, 55, 864-871.
23. McEwen, B.S. (1998). Protective and damaging effects of stress mediators. The New England Journal of Medicine, 338, 171-179.
24. McEwen, B.S., & Seeman, T. (1999). Protective and damaging effects of mediators of stress. Elaborating and testing the concepts of allostasis and allostatic load. Annals of the New York Academy of Sciences, 896, 30-47.
25. McEwen, B.S., & Stellar, E. (1993). Stress and the individual. Mechanisms leading to disease. Archives of Internal Medicine, 153, 2093-2101.
26. Michelon, E., Blaum, C., Semba, R.D., Xue, Q.L., Ricks, M.O., & Fried, L.P. (2006). Vitamin and carotenoid status in older women: Associations with the frailty syndrome. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 61, 600-607.
27. Morley, J.E., & Baumgartner, R.N. (2004). Cytokine-related aging process. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 59, M924 - M929.
28. Rockwood, K., & Mitnitski, A. (2007). Frailty in relation to the accumulation of deficits. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 62, 722-727.
29. Rockwood, K., Mitnitski, A., Song, X., Steen, B., & Skoog, I. (2006). Long-term risks of death and institutionalization of elderly people in relation to deficit accumulation at age 70. Journal of the American Geriatrics Society, 54, 975-979.
30. Seeman, T.E., Crimmins, E., Huang, M.H., Singer, B., Bucur, A., Gruenewald, T., et al. (2004). Cumulative biological risk and socio-economic differences in mortality: MacArthur studies of successful aging. Social Science and Medicine (1982). 58, 1985-1997.
31. Seeman, T.E., McEwen, B.S., Rowe, J.W., & Singer, B.H. (2001). Allostatic load as a marker of cumulative biological risk: MacArthur studies of successful aging. Proceedings of the National Academy of Sciences of the USA, 98, 4770-4775.
32. Seeman, T.E., Singer, B.H., Rowe, J.W., Horwitz, R.I., & McEwen, B.S. (1997). Price of adaptation-allostatic load and its health consequences. MacArthur studies of successful aging. Archives of Internal Medicine, 157, 2259-2268.
33. Seeman, T.E., Singer, B.H., Ryff, C.D., Dienberg, L.G., & Levy-Storms, L. (2002). Social relationships, gender, and allostatic load across two age cohorts. Psychosomatic Medicine, 64, 395-406.
34. Semba, R.D., Bartali, B., Zhou, J., Blaum, C., Ko, C.W., & Fried, L.P. (2006). Low serum micronutrient concentrations predict frailty among older women living in the community. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 61, 594-599.
35. Seplaki, C.L., Goldman, N., Glei, D., & Weinstein, M. (2005). A comparative analysis of measurement approaches for physiological dysregulation in an older population. Experimental Gerontology, 40, 438-449.
36. Seplaki, C.L., Goldman, N., Weinstein, M., & Lin, Y.H. (2006). Measurement of cumulative physiological dysregulation in an older population. Demography, 43, 165-183.
37. Stata Corporation. (1999). Stata reference manual: Release 6. College Station, TX: Stata Press.
38. Szanton, S.L., Gill, J.M., & Allen, J.K. (2005). Allostatic load: A mechanism of socioeconomic health disparities ? Biological Research for Nursing, 7, 7-15.
39. Visser, M., Pahor, M., Taaffe, D.R., Goodpaster, B.H., Simonsick, E.M., Newman, A.B., et al. (2002). Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: The health ABC study. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 57, M326 - M332.
40. Walston, J., Hadley, E.C., Ferrucci, L., Guralnik, J.M., Newman, A.B., Studenski, S.A., et al. (2006). Research agenda for frailty in older adults: Toward a better understanding of physiology and etiology: Summary from the american geriatrics Society/National institute on aging research conference on frailty in older adults. Journal of the American Geriatrics Society, 54, 991-1001.
41. Woods, N.F., LaCroix, A.Z., Gray, S.L., Aragaki, A., Cochrane, B.B., Brunner, R.L., et al. (2005). Frailty: Emergence and consequences in women aged 65 and older in the women's health initiative observational study. Journal of the American Geriatrics Society, 53, 1321-1330.