A characteristic Glu17 residue of pig carnitine palmitoyltransferase 1 is responsible for the low Km for carnitine and the low sensitivity to malonyl-CoA inhibition of the enzyme

FEBS Journal

Volumn 276, Issue 1, 2009, Pages 210-218

  Relat, Joana ^a   Pujol Vidal, Magdalena ^a   Haro, Diego ^a   Marrero, Pedro F ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Carnitine affinity; Fatty acid oxidation; Human CPT1B; Malonyl CoA inhibition; Pig CPT1B

Indexed keywords

CARNITINE; CARNITINE PALMITOYLTRANSFERASE I; GLUTAMIC ACID; MALONYL COENZYME A;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; ENZYME INHIBITION; FATTY ACID OXIDATION; NONHUMAN; PRIORITY JOURNAL; SWINE;

AMINO ACID SUBSTITUTION; ANIMALS; CARNITINE; CARNITINE O-PALMITOYLTRANSFERASE; ENZYME INHIBITORS; GLUTAMIC ACID; HUMANS; KINETICS; MALONYL COENZYME A; MICROSOMES; MITOCHONDRIA; NEURONS; SEQUENCE DELETION; SWINE;

RATTUS; SUIDAE;

EID: 57649142833     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06774.x     Document Type: Article

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