A single amino acid change (substitution of glutamate 3 with alanine) in the N-terminal region of rat liver carnitine palmitoyltransferase I abolishes malonyl-CoA inhibition and high affinity binding

Journal of Biological Chemistry

Volumn 274, Issue 14, 1999, Pages 9421-9426

  Shi, Jianying ^a   Zhu, Hongfa ^a   Arvidson, Dennis N ^a   Woldegiorgis, Gebre ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CARNITINE PALMITOYLTRANSFERASE; GLUTAMIC ACID; MALONYL COENZYME A;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CATALYSIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ALANINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BLOTTING, WESTERN; CARNITINE O-PALMITOYLTRANSFERASE; GLUTAMIC ACID; LIVER; MALONYL COENZYME A; MOLECULAR SEQUENCE DATA; POINT MUTATION; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033515467     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.14.9421     Document Type: Article

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