Substitution of glutamate-3, valine-19, leucine-23, and serine-24 with alanine in the N-terminal region of human heart muscle carnitine palmitoyltransferase I abolishes malonyl CoA inhibition and binding

Archives of Biochemistry and Biophysics

Volumn 413, Issue 1, 2003, Pages 67-74

  Zhu, Hongfa ^a,b   Shi, Jianying ^a,c   Treber, Michelle ^a   Dai, Jia ^a   Arvidson, Dennis N ^a,d   Woldegiorgis, Gebre ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^d MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Essential N terminal residues; Malonyl CoA inhibition; Muscle carnitine palmitoyltransferase I

Indexed keywords

ALANINE; CARNITINE PALMITOYLTRANSFERASE; GLUTAMIC ACID; LEUCINE; MALONYL COENZYME A; SERINE; VALINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CATALYSIS; ENZYME BINDING; ENZYME INHIBITION; HEART MUSCLE; MUTAGENESIS; MUTATION; PRIORITY JOURNAL;

EID: 0037405394     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-9861(03)00081-X     Document Type: Article

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