The mitochondrial intermembrane loop region of rat carnitine palmitoyltransferase 1A is a major determinant of its malonyl-CoA sensitivity

Journal of Biological Chemistry

Volumn 281, Issue 44, 2006, Pages 32946-32952

  Borthwick, Karen ^a   Jackson, Vicky N ^a   Price, Nigel T ^a   Zammit, Victor A ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LOOP SEQUENCE; POLYTOPIC CONFORMATION; TRANSMEMBRANE (TM);

CELL MEMBRANES; CONFORMATIONS; ENZYME INHIBITION; MUTAGENESIS;

ENZYMES;

CARNITINE PALMITOYLTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE 1A; CARNITINE PALMITOYLTRANSFERASE 1B; MALONYL COENZYME A; MUTANT PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHIMERA; ENZYME INHIBITION; ENZYME KINETICS; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN INTERACTION;

AMINO ACID SEQUENCE; ANIMALS; CARNITINE O-PALMITOYLTRANSFERASE; GENE DELETION; ISOENZYMES; KINETICS; MALONYL COENZYME A; MITOCHONDRIAL MEMBRANES; MOLECULAR SEQUENCE DATA; MUTATION; PROLINE; RATS; SENSITIVITY AND SPECIFICITY; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

EID: 33845964421     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M600843200     Document Type: Article

References (30)

1. Zammit, V. A. (1999) Biochem. J. 343, 505-515
2. Fraser, F., Corstorphine, C. G., and Zammit, V. A. (1997) Biochem. J. 323, 711-718
3. Cook, G. A. (1984) J. Biol. Chem. 259, 12030-12033
4. Grantham, B. D., and Zammit, V. A. (1986) Biochem. J. 239, 485-488
5. Grantham, B. D., and Zammit, V. A. (1988) Biochem. J. 249, 409-414
6. Ontko, J. A., and Johns, M. L. (1980) Biochem. J. 192, 959-962
7. Wong, S. H., Nestel, P. J., Trimble, R. P., Storer, G. B., Illman, R. J., and Topping, D. L. (1984) Biochim. Biophys. Acta 792, 103-109
8. Zammit, V., Corstorphine, C., Kolodziej, M., and Fraser, F. (1998) Lipids 33, 371-376
9. Zammit, V. A., Fraser, F., and Corstorphine, C. G. (1997) Adv. Enzyme. Regul. 37, 295-317
10. Kolodziej, M. P., and Zammit, V. A. (1990) Biochem. J. 272, 421-425
11. Faye, A., Borhtwick, K., Price, N., Esnous, C., Jackson, V., Zammit, V., Girard, J., and Prip-Buus, C. (2005) Biochem. J. 387, 67-76
12. Shi, J., Zhu, H., Arvidson, D. N., and Woldegiorgis, G. (1999) J. Biol. Chem. 274, 9421-9426
13. Jackson, V., Price, N., and Zammit, V. (2001) Biochemistry 40, 14629-14634
14. Jackson, V. N., Zammit, V. A., and Price, N. T. (2000) J. Biol. Chem. 275, 38410-38416
15. Lemmon, M. A., and Engelman, D. M. (1994) Q. Rev. Biophys. 27, 157-218
16. Lemmon, M. A., Treutlein, H. R., Adams, P. D., Brunger, A. T., and Engelman, D. M. (1994) Nat. Struct. Biol. 1, 157-163
17. Popot, J. L., and Engelman, D. M. (2000) Annu. Rev. Biochem. 69, 881-922
18. Jackson, V. N., Cameron, J. M., Fraser, F., Zammit, V. A., and Price, N. T. (2000) J. Biol. Chem. 275, 19560-19566
19. Van Der Leij, F. R., Cox, K. B., Jackson, V. N., Huijkman, N. C., Bartelds, B., Kuipers, J. R., Dijkhuizen, T., Terpstra, P., Wood, P. A., Zammit, V. A., and Price, N. T. (2002) J. Biol. Chem. 277, 26994-27005
20. Park, E. A., and Cook, G. A. (1998) Mol. Cell Biochem. 180, 27-32
21. Kraegen, E. W., Saha, A. K., Preston, E., Wilks, D., Hoy, A. J., Cooney, G. J., and Ruderman, N. B. (2005) Am. J. Physiol. 290, E471-E479
22. Obici, S., Feng, Z., Arduini, A., Conti, R., and Rossetti, L. (2003) Nat. Med. 9, 756-761
23. Corkey, B. E., Deeney, J. T., Yaney, G. C., Tornheim, K., and Prentki, M. (2000) J. Nutr. 130, (Suppl. 2S) 299S-304S
24. Zammit, V. (1999) Progr. Lipid Res. 38, 199-224
25. Fraser, F., Padovese, R., and Zammit, V. A. (2001) J. Biol. Chem. 276, 20182-20185
26. Prip-Buus, C., Cohen, I., Kohl, C., Esser, V., McGarry, J. D., and Girard, J. (1998) FEBS Lett. 429, 173-178
27. Hsiao, Y. S., Jogl, G., and Tong, L. (2004) J. Biol. Chem. 279, 31584-31589
28. Jogl, G., Hsiao, Y. S., and Tong, L. (2004) Ann. N. Y. Acad. Sci. 1033, 17-29
29. Jogl, G., and Tong, L. (2003) Cell 112, 113-122
30. Morillas, M., Lopez, V. E., Valencia, A., Serra, D., Gomez-Puertas, P., Hegardt, F. G., and Asins, G. (2004) Biochem. J. 379, 777-784