Genetic inactivation of adenosine A2A receptors attenuates acute traumatic brain injury in the mouse cortical impact model

Experimental Neurology

Volumn 215, Issue 1, 2009, Pages 69-76

  Li, Wei ^a   Dai, Shuangshuang ^a   An, Jianhong ^a   Xiong, Renping ^a   Li, Ping ^a   Chen, Xingyun ^a   Zhao, Yan ^a   Liu, Ping ^a   Wang, Hua ^a   Zhu, Peifang ^a   Chen, Jiangfan ^b   Zhou, Yuanguo ^a  

^a Burns and Combined Injury   (China)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine A2A receptor; Cortical impact injury, glutamate; Inflammatory cytokines; Traumatic brain injury

Indexed keywords

ADENOSINE A2A RECEPTOR; GLUTAMIC ACID; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; BRAIN CORTEX; BRAIN LEVEL; BRAIN WATER; CONTROLLED STUDY; EXPERIMENTAL MODEL; GENE EXPRESSION; GENE INACTIVATION; HISTOPATHOLOGY; KNOCKOUT MOUSE; MALE; MOUSE; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRAUMATIC BRAIN INJURY;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN EDEMA; BRAIN INJURIES; CELL DEATH; CEREBRAL CORTEX; CYTOKINES; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FUNCTIONAL LATERALITY; GENE EXPRESSION REGULATION; GLUTAMIC ACID; IN SITU NICK-END LABELING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVOUS SYSTEM DISEASES; RECEPTOR, ADENOSINE A2A; STATISTICS, NONPARAMETRIC;

EID: 57649109608     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2008.09.012     Document Type: Article

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