Structural correlates of implicit learning deficits in subjects with developmental dyslexia

Annals of the New York Academy of Sciences

Volumn 1145, Issue , 2008, Pages 212-221

  Menghini, Deny ^a,b   Hagberg, Gisela E ^b   Petrosini, Laura ^b,c   Bozzali, Marco ^b   Macaluso, Emiliano ^b   Caltagirone, Carlo ^b,d   Vicari, Stefano ^a,e  

^a BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d UNIVERSITY OF ROME TOR VERGATA   (Italy)

^e LUMSA UNIVERSITY   (Italy)

Author keywords

Developmental disorders; Developmental dyslexia; Implicit memory; Volumetric MRI; Voxel based morphometry

Indexed keywords

ADULT; BRAIN MAPPING; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; DYSLEXIA; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; IMAGE ANALYSIS; IMPLICIT MEMORY; LEARNING DISORDER; MALE; MOTOR CORTEX; PARIETAL LOBE; PHONETICS; READING; TASK PERFORMANCE;

EID: 57649108742     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1416.010     Document Type: Conference Paper

References (65)

1. American Psychiatric Association. 1994. Diagnostic and statistical manual of mental disorders, 4th edition [DSM-IV]. Washington, DC : American Psychiatric Association.
2. Ashburner, J., & Friston, K. J. 2000. Voxel-based morphometry: the methods. Neuroimage, 11 : 805 821.
3. Brambati, S. M., Termine, C., Ruffino, M., Danna, M., Lanzi, G., Stella, G., et al. 2004. Regional reductions of gray matter volume in familial dyslexia. Neurology, 63 : 742 745.
4. Brown, W. E., Eliez, S., Menon, V., Rumsey, J. M., White, C. D., & Reiss, A. L. 2001. Preliminary evidence of widespread morphological variations of the brain in dyslexia. Neurology, 56 : 781 783.
5. Chang, F., Dell, G. S., Bock, K., & Griffin, Z. M. 2000. Structural priming as implicit learning: a comparison of models of sentence production. Journal of Psycholinguistic Research, 29 (2 217 229.
6. Clark, R. E., & Squire, L. R. 1998. Classical conditioning and brain systems: the role of awareness. Science, 280 : 77 81.
7. Committeri, G., Galati, G., Paradis, A. L., Pizzamiglio, L., Berthoz, A., & LeBihan, D. 2004. Reference frames for spatial cognition: different brain areas are involved in viewer-, object-, and landmark-centered judgments about object location. Journal of Cognitive Neuroscience, 16 : 1517 1535.
8. Committeri, G., Pitzalis, S., Galati, G., Patria, F., Pelle, G., Sabatini, U., et al. 2007. Neural bases of personal and extrapersonal neglect in humans. Brain, 130 : 431 441.
9. Corbetta, M. 1998. Frontoparietal cortical networks for directing attention and the eye to visual locations: identical, independent, or overlapping neural systems? Proceedings of the National Academy of Sciences of the United States of America, 95 : 831 838.
10. Corbetta, M., Kincade, J. M., Ollinger, J. M., McAvoy, M. P., & Shulman, G. L. 2000. Voluntary orienting is dissociated from target detection in human posterior parietal cortex. Nature Neuroscience, 3 : 292 297.
11. Corbetta, M., Miezin, F.M., Shulman, G.L., & Petersen, S.E. 1993. A PET study of visuospatial attention. Journal of Neuroscience, 13 : 1202 1226.
12. Culham, J. C., & Kahnwishher, N. G. 2001. Neuroimaging of cognitive functions in human parietal cortex. Current Opinion in Neurobiology, 11 : 157 163.
13. Curran, T. 1997. Implicit sequence learning from a cognitive neuroscience perspective. In M. A. Stadler & P. A. Frensch (Eds. Handbook of implicit learning (pp. 365 400). Thousand Oaks, CA : Sage Publications.
14. Demonet, J. F. 2004. Developmental dyslexia. Lancet, 9419 : 1451 1460.
15. Desmond, J., & Fiez, J. 1998. Neuroimaging studies of the cerebellum: language, learning and memory. Trends in Cognitive Science, 2 : 355 362.
16. Doyon, J., Gaudreau, D., Laforce, R., Castonguay, M., Bédard, F., & Bouchard, J.-P. 1997. Role of the striatum, cerebellum, and frontal lobes in the learning of a visual sequence. Brain & Cognition, 34 : 218 245.
17. Eden, G. F., Howard, J. H., Jr., Howard, D. V., & Japikse, K. C. 2006. Dyslexics are impaired on implicit higher-order sequence learning, but not on implicit spatial context learning. Neuropsychologia, 44 : 1131 1144.
18. Eden, G. F., VanMeter, J. W., Rumsey, J. M., Maisog, J. M., Woods, R. P., & Zeffiro, T. A. 1996. Abnormal processing of visual motion in dyslexia revealed by functional brain imaging. Nature, 382 : 66 69.
19. Exner, C., Koschack, J., & Irle, E. 2002. The differential role of premotor frontal cortex and basal ganglia in motor sequence learning: evidence from focal basal ganglia lesions. Learning & Memory, 9 : 376 386.
20. Ferraro, F.R., Balota, D.A., & Connor, L.T. 1993. Implicit memory and the formation of new associations in nondemented Parkinson's disease individuals and individuals with senile dementia of the Alzheimer type: a serial reaction time (SRT) investigation. Brain and Cognition, 21 : 163 180.
21. Fisher, S. E., & DeFries, J. C. 2002. Developmental dyslexia: genetic dissection of a complex cognitive trait. Nature Review of Neuroscience, 3 : 767 780.
22. Galaburda, A. M., Sherman, G. F., Rosen, G. D., Aboitiz, F., & Geschwind, N. 1985. Developmental dyslexia: four consecutive patients with cortical anomalies. Annals of Neurology, 18 : 222 233.
23. Gaux, C., & Gombert, J. E. 1999. Implicit and explicit syntactic knowledge and reading in pre-adolescents. British Journal of Developmental Psychology, 17 : 169 188.
24. Gomez-Beldarrain, M., Garcia-Monco, J.C., Rubio, B., & Pascual-Leone, A. 1998. Effect of focal cerebellar lesions on procedural learning in the serial reaction time task. Experimental Brain Research, 120 : 25 30.
25. Good, C. D., Johnsrude, I. S., Ashburner, J., Henson, R. N., Friston, K. J., & Frackowiak R. S. 2001. A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage, 14 : 21 36.
26. Goswami, U. 2006. Sensorimotor impairments in dyslexia: getting the beat. Developmental Science, 9 : 257 259.
27. Grafton, S. T., Hazeltine, E., & Ivry, R. B. 1995. Functional mapping of sequence learning in normal humans. Journal of Cognitive Neuroscience, 7 : 497 510.
28. Grafton, S. T., Hazeltine, E., & Ivry, R. B. 1998. Abstract and effector-specific representations of motor sequences identified with PET. Journal of Neuroscience, 18 : 9420 9428.
29. Halsband, U., & Passingham, R.E. 1985. Premotor cortex and the conditions for movement in monkey (Macaca fascicularis). Behavioural Brain Research, 18 : 69 277.
30. Hazeltine, E., Grafton, S. T., & Ivry, R. B. 1997. Attention and stimulus characteristics determine the locus of motor-sequence encoding a PET study. Brain, 120 : 123 140.
31. Howard, J. H., Howard, D. V., Japikse, K. C., & Eden, G. F. 2006. Dyslexics are impaired on implicit higher-order sequence learning, but not on implicit spatial context learning. Neuropsychologia, 44 : 1131 1144.
32. Jackson, G.M., Jackson, S.R., Harrison, J., Henderson, L., & Kennard, C. 1995. Serial reaction time learning and Parkinson's disease: evidence for a procedural learning deficit. Neuropsychologia, 33 : 577 593.
33. Jenkins, I.H., Brooks, D.J., Nixon, P.D., Frackowiak, R.S.J., & Passingham, R.E. 1994. Motor sequence learning: a study with positron emission tomography. Journal of Neuroscience, 14 : 3775 3790.
34. Jueptner, M., Stephan, K.M., Frith, C.D., Brooks, D.J., Frackowiak, R.S.J., & Passingham, R.E. 1997. Anatomy of motor learning. II. Subcortical structures and learning by trial and error. Journal of Neurophysiology, 77 : 1325 1337.
35. Knopman, D., & Nissen, M.J. 1991. Procedural learning is impaired in Huntington's disease: evidence from the serial reaction time task. Neuropsychologia, 29 : 245 254.
36. Lyytinen, H., Aro, M., Eklund, K., Erskine, J., Guttorm, T., Laakso, M. L., et al. 2004. The development of children at familial risk for dyslexia: birth to early school age. Annals of Dyslexia, 54 : 184 220.
37. Menghini, D., Hagberg, G. E., Caltagirone, C., Petrosini, L., & Vicari, S. 2006. Implicit learning deficits in dyslexic adults: an fMRI study. NeuroImage, 33 : 1218 1226.
38. Molinari, M., Leggio, M.G., Solida, A., Ciorra, R., Misciagna, S., Silveri, M.C., et al. 1997. Cerebellum and procedural learning: evidence from focal cerebellar lesions. Brain, 120 : 1753 1762.
39. Müller, R. A., Kleinhans, N., Pierce, K., Kemmotsu, N., & Courchesne, E. 2002. Functional MRI of motor sequence acquisition: effects of learning stage and performance. Cognitive Brain Research, 14 : 277 293.
40. Nicolson, R. I., & Fawcett, A. J. 1990. Automaticity: a new framework for dyslexia research? Cognition, 35 : 159 182.
41. Nissen, M. J., & Bullemer, P. 1987. Attentional requirements of learning: evidence from performance measures. Cognitive Psychology, 19 : 1 32.
42. Pascual-Leone, A., Grafman, J., Clark, K., Steward, M., Massaquoi, S., Lou, J.-S., et al. 1993. Procedural learning in Parkinson's disease and cerebellar degeneration. Annals of Neurology, 34 : 594 602.
43. Paulesu, E., Démonet, J. F., Fazio, F., McCrory, E., Chanoine, V., Brunswick, N., et al. 2001. Dyslexia: cultural diversity and biological unity. Science, 291 : 2064 2065.
44. Pennington, B. F., & Gilger, J. W. 1996. How is dyslexia transmitted?. In C. H. Chase, G. D. Rosen, & G. F. Sherman (Eds Developmental dyslexia: neural, cognitive, and genetic mechanisms (pp. 41 61). Baltimore, MD : York Press.
45. Rauch, S. L. Savage, C. R., Brown, H. D., Curran, T., Alpert, N. M., Kendrick, A., et al. 1995. A PET investigation of implicit and explicit sequence learning. Human Brain Mapping, 3 : 271 286.
46. Rauch, S. L., Whalen, P. J., Savage, C. R., Curran, T., Kendrick, A., Brown, H. D., et al. 1997. Striatal recruitment during an implicit sequence learning task as measured by functional magnetic resonance imaging. Human Brain Mapping, 5 : 124 132.
47. Richter, S., Matthies, K., Ohde, T, Dimitrova, A, Gizewski, E, Beck, A., et al. 2004. Stimulus-response versus stimulus-stimulus-response learning in cerebellar patients. Experimental Brain Research, 158 (4 438 449.
48. Rorden, C. & Brett, M. 2000. Stereotaxic display of brain lesions. Behavioural Neurology, 12 : 191 200.
49. Sadato, N., Campbell, G., Ibáñez, V., Deiber, M., & Hallett, M. 1996. Complexity affects regional cerebral blood flow change during sequential finger movements. Journal of Neuroscience, 16 : 2691 2700.
50. Sakai, K., Hikosaka, O., Miyachi, S., Takino, R., Sasaki, Y., & Pütz, B. 1998. Transition of brain activation from frontal to parietal areas in visuomotor sequence learning. Journal of Neuroscience, 18 : 1827 1840.
51. Sartori, G., Job, R., & Tressoldi, P. E. 1995. Batteria per la valutazione della dislessia e della disortografia evolutiva. Firenze : Edizioni O.S.
52. Share, D. L. 1995. Phonological receding and self-teaching: sine qua non of reading acquisition. Cognition, 55 : 151 218.
53. Shaywitz, B. A., Shaywitz, S. E., Pugh, K. R., Mencl, W. E., Fulbright, R. K., Skudlarski, P., et al. 2002. Disruption of posterior brain systems for reading in children with developmental dyslexia. Biological Psychiatry, 52 (2 101 110.
54. Shaywitz, S. 1998. Current concepts: dyslexia. New England Journal of Medicine, 338 : 307 312.
55. Silani, G., Frith, U., Demonet, J. F., Fazio, F., Perani, D., Price, C., et al. 2005. Brain abnormalities underlying altered activation in dyslexia: a voxel based morphometry study. Brain, 23 : 1 9.
56. Snowling, M. J. 2001. From language to reading and dyslexia. Dyslexia, 7 : 37 46.
57. Sperling, A. J., Lu, Z. L., & Manis, F. R. 2004. Slower implicit categorical learning in adult poor readers. Annals of Dyslexia, 54 : 281 303.
58. Talairach, J., & Tournoux, P. 1988. Co-planar stereotaxic atlas of the human brain: A 3-dimensional proportional system, an approach to cerebral imaging. New York : Thieme.
59. Tallal, P., Miller, S., & Fitch, R. H. 1993. Neurobiological basis of speech: a case for the preeminence of temporal processing [review]. Annals of the New York Academy of Sciences, 682 : 27 47.
60. Torriero, S., Olivieri, M., Koch, G., Caltagirone, C., & Petrosini, L. 2004. Interference of left and right cerebellar rTMS with procedural learning. Journal of Cognitive Neuroscience, 16 : 1605 1611.
61. Tzourio-Mazoyer, N., Landeau, B., Papathanassiou, D., Crivello, F., Etard, O., Delcroix, N., et al. 2002. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI- MRI single-subject brain. NeuroImage, 15 : 273 289.
62. Van Ingelghem, M., van Wieringen, A., Wouters, J., Vandenbussche, E., Onghena, P., & Ghesquière, P. 2001. Psychophysical evidence for a general temporal processing deficit in children with dyslexia. Neuroreport, 12 : 3603 3607.
63. Vicari, S., Finzi, A., Menghini, D., Marotta, L., Baldi, S., & Petrosini, L. 2005. Do children with developmental dyslexia have an implicit learning deficit? Journal of Neurology, Neurosurgery, and Psychiatry, 76 : 1392 1397.
64. Vinckenbosch, E., Robichon, F. & Eliez, S. 2005. Gray matter alteration in dyslexia: converging evidence from volumetric and voxel-by-voxel MRI analyses. Neuropsychologia, 43 : 324 331.
65. Willingham, D. B., Salidis, J., & Gabrieli, J. D. E. 2002. Direct comparison of neural systems mediating conscious and unconscious skill learning. Journal of Neurophysiology, 88 : 1451 1460.