메뉴 건너뛰기




Volumn 14, Issue 12, 2008, Pages

The retinoblastoma paradigm revisited

Author keywords

"Two hit" theory; Aneuploidy; Cancer genetics; Epigenetics; Gene mutations; Retinoblastoma

Indexed keywords

ANEUPLOIDY; CANCER GENETICS; CHILDHOOD CANCER; DISEASE ASSOCIATION; DNA TUMOR VIRUS; EPIGENETICS; FAMILIAL CANCER; GENE MUTATION; HUMAN; INTRAOCULAR TUMOR; NONHUMAN; ONSET AGE; PATHOGENESIS; RETINOBLASTOMA; REVIEW; SYSTEMATIC REVIEW; TUMOR DIAGNOSIS; TUMOR SUPPRESSOR GENE; WART VIRUS;

EID: 57349196431     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (23)

References (105)
  • 2
    • 10644267600 scopus 로고    scopus 로고
    • Continuing challenges in the management of Rb with chemotherapy
    • Shields CL, Meadows AT, Leahey AM, Shields JA: Continuing challenges in the management of Rb with chemotherapy. Retina, 2004; 24(6): 849-62
    • (2004) Retina , vol.24 , Issue.6 , pp. 849-862
    • Shields, C.L.1    Meadows, A.T.2    Leahey, A.M.3    Shields, J.A.4
  • 3
    • 0015043748 scopus 로고
    • Mutation and cancer: Statistical study of Rb
    • Knudson AG: Mutation and cancer: statistical study of Rb. Proc Nat Acad Sci USA, 1971; 68(4): 820-23
    • (1971) Proc Nat Acad Sci USA , vol.68 , Issue.4 , pp. 820-823
    • Knudson, A.G.1
  • 4
    • 0016134997 scopus 로고
    • Heredity and human cancer
    • Knudson AG Jr: Heredity and human cancer. Am J Pathol, 1974; 77: 1. 77-84
    • (1974) Am J Pathol , vol.77 , Issue.1 , pp. 77-84
    • Knudson Jr, A.G.1
  • 5
    • 0016682680 scopus 로고
    • The genetics of childhood cancer
    • Knudson AG: The genetics of childhood cancer. Cancer, 1975; 3(Suppl.): 1022-26
    • (1975) Cancer , vol.3 , Issue.SUPPL. , pp. 1022-1026
    • Knudson, A.G.1
  • 6
    • 0016807269 scopus 로고
    • Genetics of human cancer
    • Knudson AG: Genetics of human cancer. Genetics, 1975; 79(Suppl.): 305-16
    • (1975) Genetics , vol.79 , Issue.SUPPL. , pp. 305-316
    • Knudson, A.G.1
  • 7
    • 0039712065 scopus 로고
    • Mutation and childhood cancer: A probabilistic model for the incidence of Rb
    • Knudson AG: Mutation and childhood cancer: a probabilistic model for the incidence of Rb. Proc Natl Acad Sci, 1975; 72(12): 5116-20
    • (1975) Proc Natl Acad Sci , vol.72 , Issue.12 , pp. 5116-5120
    • Knudson, A.G.1
  • 8
    • 0017724098 scopus 로고
    • Mutation and cancer in man
    • Knudson AG: Mutation and cancer in man. Cancer, 1977; 39(Suppl.4): 1882-86
    • (1977) Cancer , vol.39 , Issue.SUPPL.4 , pp. 1882-1886
    • Knudson, A.G.1
  • 9
    • 0018148959 scopus 로고
    • Model for the incidence of embryonal cancers: Application to Rb
    • Knudson AG: Model for the incidence of embryonal cancers: application to Rb. Proc Natl Acad Sci, 1978; 75(5): 2453-57
    • (1978) Proc Natl Acad Sci , vol.75 , Issue.5 , pp. 2453-2457
    • Knudson, A.G.1
  • 10
    • 84944659585 scopus 로고
    • Hereditary cancer
    • Knudson AG: Hereditary cancer. JAMA, 1979; 241(3): 279
    • (1979) JAMA , vol.241 , Issue.3 , pp. 279
    • Knudson, A.G.1
  • 11
    • 0018698006 scopus 로고
    • Persons at high risk of cancer
    • Knudson AG: Persons at high risk of cancer. N Engl J Med, 1979; 301(11): 606-7
    • (1979) N Engl J Med , vol.301 , Issue.11 , pp. 606-607
    • Knudson, A.G.1
  • 12
    • 0018828848 scopus 로고
    • Genetics and cancer
    • Knudson AG: Genetics and cancer. Am J Med, 1980; 69(1): 1-3
    • (1980) Am J Med , vol.69 , Issue.1 , pp. 1-3
    • Knudson, A.G.1
  • 13
    • 0021879645 scopus 로고
    • Hereditary cancer, oncogenes, and antioncogenes
    • Knudson AG: Hereditary cancer, oncogenes, and antioncogenes. Cancer Res, 1985; 45(4): 1437-43
    • (1985) Cancer Res , vol.45 , Issue.4 , pp. 1437-1443
    • Knudson, A.G.1
  • 14
    • 0024557049 scopus 로고
    • Hereditary cancers disclose a class of cancer genes
    • Knudson AG: Hereditary cancers disclose a class of cancer genes. Cancer, 1989; 63(10): 1888-91
    • (1989) Cancer , vol.63 , Issue.10 , pp. 1888-1891
    • Knudson, A.G.1
  • 15
    • 0027504088 scopus 로고
    • Antioncogenes and human cancer
    • Knudson AG: Antioncogenes and human cancer. Proc Natl Acad Sci, 1993; 90(23): 10914-21
    • (1993) Proc Natl Acad Sci , vol.90 , Issue.23 , pp. 10914-10921
    • Knudson, A.G.1
  • 16
    • 0029445186 scopus 로고
    • Hereditary cancers: From discovery to intervention
    • Knudson AG: Hereditary cancers: from discovery to intervention. J Natl Cancer Inst Monogr, 1995; 17: 5-7
    • (1995) J Natl Cancer Inst Monogr , vol.17 , pp. 5-7
    • Knudson, A.G.1
  • 17
    • 0029919109 scopus 로고    scopus 로고
    • Hereditary cancer: Two hits revisited
    • Knudson AG: Hereditary cancer: two hits revisited. J Cancer Res Clin Oncol, 1996; 122(3): 135-40
    • (1996) J Cancer Res Clin Oncol , vol.122 , Issue.3 , pp. 135-140
    • Knudson, A.G.1
  • 18
    • 0037157786 scopus 로고    scopus 로고
    • Cancer genetics
    • Knudson AG: Cancer genetics. Am J Med Genet, 2002; 111(1): 96-102
    • (2002) Am J Med Genet , vol.111 , Issue.1 , pp. 96-102
    • Knudson, A.G.1
  • 19
    • 0344412837 scopus 로고    scopus 로고
    • Cancer genetics through a personal retrospectroscope
    • Knudson AG: Cancer genetics through a personal retrospectroscope. Genes Chromosomes Cancer, 2003; 38(4): 288-91
    • (2003) Genes Chromosomes Cancer , vol.38 , Issue.4 , pp. 288-291
    • Knudson, A.G.1
  • 20
    • 1642514808 scopus 로고    scopus 로고
    • Of sea urchins and worms: Development and cancer
    • Knudson AG: Of sea urchins and worms: development and cancer. Cell Death Differ, 2004; 11(1): 11-12
    • (2004) Cell Death Differ , vol.11 , Issue.1 , pp. 11-12
    • Knudson, A.G.1
  • 21
    • 25844499158 scopus 로고    scopus 로고
    • A personal sixty-year tour of genetics and medicine
    • Epub ahead of print
    • Knudson AG: A personal sixty-year tour of genetics and medicine. Ann Rev Gen Hum Genet, 2005; [Epub ahead of print]; http://www.cancerindex.org/ geneweb/RB1.htm#t51
    • (2005) Ann Rev Gen Hum Genet
    • Knudson, A.G.1
  • 22
    • 42449127634 scopus 로고    scopus 로고
    • Diagnosis, classification, and treatment of Rb
    • Kiss S, Leiderman YI, Mukai S: Diagnosis, classification, and treatment of Rb. Int Ophthalmol Clin, 2008; 48(2): 135-47
    • (2008) Int Ophthalmol Clin , vol.48 , Issue.2 , pp. 135-147
    • Kiss, S.1    Leiderman, Y.I.2    Mukai, S.3
  • 24
    • 57349185344 scopus 로고    scopus 로고
    • http://www.geneclinics.org/profiles/Rb/details.html
  • 25
    • 84907115384 scopus 로고
    • Italian register for Rb. Pros and cons of a retrospective statistical study
    • Mastrangelo D, Acquaviva A, Di Pisa F et al: Italian register for Rb. Pros and cons of a retrospective statistical study. Ophthalmic Paediatr Genet, 1991; 12(2): 73-78
    • (1991) Ophthalmic Paediatr Genet , vol.12 , Issue.2 , pp. 73-78
    • Mastrangelo, D.1    Acquaviva, A.2    Di Pisa, F.3
  • 26
    • 35648976977 scopus 로고    scopus 로고
    • Does the evidence matter in medicine? The Rb paradigm
    • Mastrangelo D, De Francesco S, Di Leonardo A et al: Does the evidence matter in medicine? The Rb paradigm. Int J Cancer, 2007; 121(11): 2501-5
    • (2007) Int J Cancer , vol.121 , Issue.11 , pp. 2501-2505
    • Mastrangelo, D.1    De Francesco, S.2    Di Leonardo, A.3
  • 27
  • 28
    • 57349145619 scopus 로고    scopus 로고
    • http://www.ruf.rice.edu/~lane/stat_sim/descriptive/index.html
  • 29
    • 0002393922 scopus 로고
    • Genetics of Rb
    • Shields JA, Shields CL, eds, Philadelphia, Pa: WB Saunders
    • Shields JA, Shields CL: Genetics of Rb. In: Shields JA, Shields CL, eds. Intraocular Tumors: A Text and Atlas. Philadelphia, Pa: WB Saunders, 1992; 333-40
    • (1992) Intraocular Tumors: A Text and Atlas , pp. 333-340
    • Shields, J.A.1    Shields, C.L.2
  • 30
    • 14644397851 scopus 로고    scopus 로고
    • Diagnosis and management of Rb
    • Shields CL, Shields JA: Diagnosis and management of Rb. Cancer Control, 2004; 11(5): 317-27
    • (2004) Cancer Control , vol.11 , Issue.5 , pp. 317-327
    • Shields, C.L.1    Shields, J.A.2
  • 31
    • 2942574955 scopus 로고    scopus 로고
    • Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically deathresistant cell-of-origin in Rb
    • Chen D, Livne-Bar I, Vanderluit JL et al: Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically deathresistant cell-of-origin in Rb. Cancer Cell, 2004; 5: 539-51
    • (2004) Cancer Cell , vol.5 , pp. 539-551
    • Chen, D.1    Livne-Bar, I.2    Vanderluit, J.L.3
  • 32
    • 2942512013 scopus 로고    scopus 로고
    • Cell type-specific effects of Rb deletion in the murine retina
    • MacPherson D, Sage J, Kim T et al: Cell type-specific effects of Rb deletion in the murine retina. Genes Dev, 2004; 18: 1681-94
    • (2004) Genes Dev , vol.18 , pp. 1681-1694
    • MacPherson, D.1    Sage, J.2    Kim, T.3
  • 33
    • 1842588322 scopus 로고    scopus 로고
    • Rb regulates proliferation and rod photoreceptor development in the mouse retina
    • Zhang J, Gray J, Wu L et al: Rb regulates proliferation and rod photoreceptor development in the mouse retina. Nat Genet, 2004; 36: 351-60
    • (2004) Nat Genet , vol.36 , pp. 351-360
    • Zhang, J.1    Gray, J.2    Wu, L.3
  • 34
    • 33745304849 scopus 로고    scopus 로고
    • Compensation by tumor suppressor genes during retinal development in mice and humans
    • Donovan SL, Schweers B, Martins R et al: Compensation by tumor suppressor genes during retinal development in mice and humans. BMC Biol, 2006; 4: 14
    • (2006) BMC Biol , vol.4 , pp. 14
    • Donovan, S.L.1    Schweers, B.2    Martins, R.3
  • 35
    • 0031872818 scopus 로고    scopus 로고
    • Distribution of tumors in the retina in hereditary Rb patients
    • Brinkert AW, Moll AC, Jager MJ et al: Distribution of tumors in the retina in hereditary Rb patients. Ophthalmic Genet, 1998; 19(2): 63-67
    • (1998) Ophthalmic Genet , vol.19 , Issue.2 , pp. 63-67
    • Brinkert, A.W.1    Moll, A.C.2    Jager, M.J.3
  • 36
    • 35348849572 scopus 로고    scopus 로고
    • Differentiated Horizontal Interneurons Clonally Expand to Form Metastatic Rb in Mice
    • Ajioka I, Martins RAP, Bayazitov IT et al: Differentiated Horizontal Interneurons Clonally Expand to Form Metastatic Rb in Mice Cell, 2007; 131(2): 378-90
    • (2007) Cell , vol.131 , Issue.2 , pp. 378-390
    • Ajioka, I.1    Martins, R.A.P.2    Bayazitov, I.T.3
  • 37
    • 35348829231 scopus 로고    scopus 로고
    • te Riele H: Rb teaches a new lesson. Cell, 2007; 131(2): 227-29
    • te Riele H: Rb teaches a new lesson. Cell, 2007; 131(2): 227-29
  • 38
    • 40849092627 scopus 로고    scopus 로고
    • The relationship between tumor cell differentiation and age at diagnosis in Rb
    • Madhavan J, Ganesh A, Roy J et al: The relationship between tumor cell differentiation and age at diagnosis in Rb. J Pediatr Ophthalmol Strabismus, 2008; 45(1): 22-25
    • (2008) J Pediatr Ophthalmol Strabismus , vol.45 , Issue.1 , pp. 22-25
    • Madhavan, J.1    Ganesh, A.2    Roy, J.3
  • 39
    • 0030457758 scopus 로고    scopus 로고
    • Geographic and ethnic variations in the incidence of childhood cancer
    • Stiller C, Parkin D: Geographic and ethnic variations in the incidence of childhood cancer. Br Med Bull, 1996; 52: 682-703
    • (1996) Br Med Bull , vol.52 , pp. 682-703
    • Stiller, C.1    Parkin, D.2
  • 40
    • 4444328118 scopus 로고    scopus 로고
    • Epidemiology and genetics of childhood cancer
    • Stiller CA: Epidemiology and genetics of childhood cancer. Oncogene, 2004; 23(38): 6429-44
    • (2004) Oncogene , vol.23 , Issue.38 , pp. 6429-6444
    • Stiller, C.A.1
  • 41
    • 20444395828 scopus 로고    scopus 로고
    • Fruit and vegetable intake during pregnancy and risk for development of sporadic Rb
    • Orjuela MA, Titievsky L, Liu X et al: Fruit and vegetable intake during pregnancy and risk for development of sporadic Rb. Cancer Epidemiol Biomarkers Prev, 2005; 14(6): 1433-40
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , Issue.6 , pp. 1433-1440
    • Orjuela, M.A.1    Titievsky, L.2    Liu, X.3
  • 42
    • 0033754920 scopus 로고    scopus 로고
    • Presence of human papilloma virus in tumor tissue from children with Rb: An alternative mechanism for tumor development
    • Orjuela M, Castaneda VP, Ridaura C et al: Presence of human papilloma virus in tumor tissue from children with Rb: An alternative mechanism for tumor development. Clin Cancer Res, 2000; 6: 4010-16
    • (2000) Clin Cancer Res , vol.6 , pp. 4010-4016
    • Orjuela, M.1    Castaneda, V.P.2    Ridaura, C.3
  • 43
    • 37549062918 scopus 로고    scopus 로고
    • Role of Rb-dependent and Rb-independent functions of papillomavirus E7 oncogene in head and neck cancer
    • Strati K, Lambert PF: Role of Rb-dependent and Rb-independent functions of papillomavirus E7 oncogene in head and neck cancer. Cancer Res, 2007; 67(24): 11585-93
    • (2007) Cancer Res , vol.67 , Issue.24 , pp. 11585-11593
    • Strati, K.1    Lambert, P.F.2
  • 44
    • 38149075312 scopus 로고    scopus 로고
    • Papillomavirus E6 and E7 proteins and their cellular targets
    • Wise-Draper TM, Wells SI: Papillomavirus E6 and E7 proteins and their cellular targets. Front Biosci, 2008; 13: 1003-17
    • (2008) Front Biosci , vol.13 , pp. 1003-1017
    • Wise-Draper, T.M.1    Wells, S.I.2
  • 45
    • 33847686752 scopus 로고    scopus 로고
    • Human Rb is not caused by known pRb-inactivating human DNA tumor viruses
    • Gillison ML, Chen R, Goshu E et al: Human Rb is not caused by known pRb-inactivating human DNA tumor viruses. Int J Cancer, 2007; 120(7): 1482-90
    • (2007) Int J Cancer , vol.120 , Issue.7 , pp. 1482-1490
    • Gillison, M.L.1    Chen, R.2    Goshu, E.3
  • 46
    • 33750220492 scopus 로고    scopus 로고
    • RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts
    • Iovino F, Lentini L, Amato A, Di Leonardo A: RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts. Mol Cancer, 2006; 5: 38
    • (2006) Mol Cancer , vol.5 , pp. 38
    • Iovino, F.1    Lentini, L.2    Amato, A.3    Di Leonardo, A.4
  • 47
    • 2542550364 scopus 로고    scopus 로고
    • Systematic Review of Genomic Integration Sites of Human Papillomavirus Genomes in Epithelial Dysplasia and Invasive Cancer of the Female Lower Genital Tract
    • Wentzensen N, Vinokurova S, Doeberitz MvK: Systematic Review of Genomic Integration Sites of Human Papillomavirus Genomes in Epithelial Dysplasia and Invasive Cancer of the Female Lower Genital Tract. Cancer Research, 2004; 64, 3878-84
    • (2004) Cancer Research , vol.64 , pp. 3878-3884
    • Wentzensen, N.1    Vinokurova, S.2    Doeberitz, M.K.3
  • 48
    • 44049107548 scopus 로고    scopus 로고
    • Phosphorylation of Rb protein by viral protein with cyclin-dependent kinase function
    • Hume AJ, Finkel JS, Kamil JP et al: Phosphorylation of Rb protein by viral protein with cyclin-dependent kinase function. Science, 2008; 320(5877): 797-99
    • (2008) Science , vol.320 , Issue.5877 , pp. 797-799
    • Hume, A.J.1    Finkel, J.S.2    Kamil, J.P.3
  • 49
    • 0028907719 scopus 로고
    • Spectrum of germline mutations in the RB1 gene: A study of 232 patients with hereditary and non hereditary Rb
    • Blanquet V, Turleau C, Gross-Morand MS et al: Spectrum of germline mutations in the RB1 gene: a study of 232 patients with hereditary and non hereditary Rb. Hum Mol Genet, 1995; 4(3): 383-88
    • (1995) Hum Mol Genet , vol.4 , Issue.3 , pp. 383-388
    • Blanquet, V.1    Turleau, C.2    Gross-Morand, M.S.3
  • 50
    • 46749098393 scopus 로고    scopus 로고
    • Evaluation of in silico splice tools for decision-making in molecular diagnosis
    • Houdayer C, Dehainault C, Mattler C et al: Evaluation of in silico splice tools for decision-making in molecular diagnosis. Hum Mutat, 2008
    • (2008) Hum Mutat
    • Houdayer, C.1    Dehainault, C.2    Mattler, C.3
  • 51
    • 10744228566 scopus 로고    scopus 로고
    • Comprehensive screening for constitutional RB1 mutations by DHPLC and QMPSF
    • Houdayer C, Gauthier-Villars M, LaugeA et al: Comprehensive screening for constitutional RB1 mutations by DHPLC and QMPSF. Hum Mutat, 2004; 23: 193-202
    • (2004) Hum Mutat , vol.23 , pp. 193-202
    • Houdayer, C.1    Gauthier-Villars, M.2    LaugeA3
  • 52
    • 57349094556 scopus 로고    scopus 로고
    • http://www.cancerindex.org/geneweb//RB1.htm
  • 53
    • 27844480644 scopus 로고    scopus 로고
    • RB1 gene mutation up-date, a meta-analysis based on 932 reported mutations available in a searchable database
    • Valverde JR, Alonso J, Palacios I, Pestaña A: RB1 gene mutation up-date, a meta-analysis based on 932 reported mutations available in a searchable database. BMC Genetics, 2005, 6: 53, http://www.biomedcentral.com/ 1471-2156/6/53
    • (2005) BMC Genetics , vol.6 , pp. 53
    • Valverde, J.R.1    Alonso, J.2    Palacios, I.3    Pestaña, A.4
  • 54
    • 57349107553 scopus 로고    scopus 로고
    • http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijovs/ vol1n2/gene.xml
  • 55
    • 33947310031 scopus 로고    scopus 로고
    • Environmental epigenomics and disease susceptibility
    • Jirtle RL, Skinner MK: Environmental epigenomics and disease susceptibility. Nature Reviews Genetics, 2007; 8: 252-62
    • (2007) Nature Reviews Genetics , vol.8 , pp. 252-262
    • Jirtle, R.L.1    Skinner, M.K.2
  • 56
    • 39749171775 scopus 로고    scopus 로고
    • Environmental epigenomics in human health and disease
    • Dolinoy DC, Jirtle RL: Environmental epigenomics in human health and disease. Environ Mol Mutagen, 2008; 49(1): 4-8
    • (2008) Environ Mol Mutagen , vol.49 , Issue.1 , pp. 4-8
    • Dolinoy, D.C.1    Jirtle, R.L.2
  • 57
    • 57349175300 scopus 로고    scopus 로고
    • http://www.infobiogen.fr/services/chromcancer/Genes/RB1ID90.html
  • 58
    • 33644956860 scopus 로고    scopus 로고
    • Molecular diagnostics of genetic eye diseases
    • Fan BJ, Tam PO, Choy KW et al: Molecular diagnostics of genetic eye diseases. Clin Biochem, 2006; 39(3): 231-39
    • (2006) Clin Biochem , vol.39 , Issue.3 , pp. 231-239
    • Fan, B.J.1    Tam, P.O.2    Choy, K.W.3
  • 59
    • 0037322272 scopus 로고    scopus 로고
    • Sensitive and efficient detection of RB1 gene mutations enhances care for families with Rb
    • Richter S, Vandezande K, Chen N et al: Sensitive and efficient detection of RB1 gene mutations enhances care for families with Rb. Am J Hum Genet, 2003; 72(2): 253-69
    • (2003) Am J Hum Genet , vol.72 , Issue.2 , pp. 253-269
    • Richter, S.1    Vandezande, K.2    Chen, N.3
  • 60
    • 57349151940 scopus 로고    scopus 로고
    • http://www.Rbsolutions.org/testsent.html
  • 61
    • 20344399159 scopus 로고    scopus 로고
    • Nichols KE, Houseknecht MD, Godmilow et al: Multistep clinical molecular screening of 180 unrelated individuals with Rb detects 36 novel mutations in the RB1 gene. Hum Mutat, 2005; 6: 566-74
    • Nichols KE, Houseknecht MD, Godmilow et al: Multistep clinical molecular screening of 180 unrelated individuals with Rb detects 36 novel mutations in the RB1 gene. Hum Mutat, 2005; 6: 566-74
  • 62
    • 57349089942 scopus 로고    scopus 로고
    • http://www.cancerindex.org/geneweb/RB1.htm#t51
  • 63
    • 0036903986 scopus 로고    scopus 로고
    • Missing expression of pRb2/p130 in human Rbs is associated with reduced apoptosis and lesser differentiation invest
    • Bellan C, De Falco G, Tosi GM et al: Missing expression of pRb2/p130 in human Rbs is associated with reduced apoptosis and lesser differentiation invest. Ophthalmol Vis Sci, 2002; 43: 3602-8
    • (2002) Ophthalmol Vis Sci , vol.43 , pp. 3602-3608
    • Bellan, C.1    De Falco, G.2    Tosi, G.M.3
  • 64
    • 18444379044 scopus 로고    scopus 로고
    • Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines
    • Harada K, Toyooka S, Maitra A et al: Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines. Oncogene, 2002; 21(27): 4345-49
    • (2002) Oncogene , vol.21 , Issue.27 , pp. 4345-4349
    • Harada, K.1    Toyooka, S.2    Maitra, A.3
  • 65
    • 0037108859 scopus 로고    scopus 로고
    • Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines
    • Harada K, Toyooka S, Shivapurkar N et al: Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines. Cancer Res, 2002; 62(20): 5897-901
    • (2002) Cancer Res , vol.62 , Issue.20 , pp. 5897-5901
    • Harada, K.1    Toyooka, S.2    Shivapurkar, N.3
  • 66
    • 12444250673 scopus 로고    scopus 로고
    • Aberrant methylation of the HIC1 promoter is a frequent event in specific pediatric neoplasms
    • Rathi A, Virmani AK, Harada K et al: Aberrant methylation of the HIC1 promoter is a frequent event in specific pediatric neoplasms. Clin Cancer Res, 2003; 9(10 Pt 1): 3674-78
    • (2003) Clin Cancer Res , vol.9 , Issue.10 PART 1 , pp. 3674-3678
    • Rathi, A.1    Virmani, A.K.2    Harada, K.3
  • 67
    • 19944415836 scopus 로고    scopus 로고
    • Aberrant methylation of HIN-1 (high in normal-1) is a frequent event in many human malignancies
    • Shigematsu H, Suzuki M, Takahashi T et al: Aberrant methylation of HIN-1 (high in normal-1) is a frequent event in many human malignancies. Int J Cancer, 2005; 113(4): 600-4
    • (2005) Int J Cancer , vol.113 , Issue.4 , pp. 600-604
    • Shigematsu, H.1    Suzuki, M.2    Takahashi, T.3
  • 68
    • 33750590095 scopus 로고    scopus 로고
    • Inactivation of the p53 pathway in retinoblastoma
    • Laurie NA, Donovan SL, Shih CS et al: Inactivation of the p53 pathway in retinoblastoma. Nature, 2006; 444(7115): 45-46
    • (2006) Nature , vol.444 , Issue.7115 , pp. 45-46
    • Laurie, N.A.1    Donovan, S.L.2    Shih, C.S.3
  • 70
    • 33750596704 scopus 로고    scopus 로고
    • Cancer biology: Second step to retinal tumours
    • Wallace VA: Cancer biology: Second step to retinal tumours. Nature, 2006; 444: 45-46
    • (2006) Nature , vol.444 , pp. 45-46
    • Wallace, V.A.1
  • 71
    • 0034724312 scopus 로고    scopus 로고
    • Aneuploidy vs. gene mutation hypothesis of cancer: Recent studies claims mutation but is found to support aneuploidy
    • Li R, Sonik A, Rasnik D, Duesberg P: Aneuploidy vs. gene mutation hypothesis of cancer: Recent studies claims mutation but is found to support aneuploidy. Proc Natl Acad Sci, 2000; 97(7): 3236-41
    • (2000) Proc Natl Acad Sci , vol.97 , Issue.7 , pp. 3236-3241
    • Li, R.1    Sonik, A.2    Rasnik, D.3    Duesberg, P.4
  • 72
    • 12844279839 scopus 로고    scopus 로고
    • Aneuploidy approaching a perfect score in predicting and preventing cancer
    • Duesberg P, Li R, Rasnick D: Aneuploidy approaching a perfect score in predicting and preventing cancer. Cell Cycle, 2004; 3: 823-28
    • (2004) Cell Cycle , vol.3 , pp. 823-828
    • Duesberg, P.1    Li, R.2    Rasnick, D.3
  • 73
    • 0037992405 scopus 로고    scopus 로고
    • Are cancers dependent on oncogenes or on aneuploidy?
    • Duesberg PH: Are cancers dependent on oncogenes or on aneuploidy? Cancer Genet Cytogent, 2003; 143: 89-91
    • (2003) Cancer Genet Cytogent , vol.143 , pp. 89-91
    • Duesberg, P.H.1
  • 74
    • 0038668792 scopus 로고    scopus 로고
    • Instability of chromosome structure in cancer cells increases exponentially with degrees of aneuploidy
    • Fabarius A, Hehlmann R, Duesberg PH: Instability of chromosome structure in cancer cells increases exponentially with degrees of aneuploidy. Cancer Genet Cytogenet, 2003; 143: 59-72
    • (2003) Cancer Genet Cytogenet , vol.143 , pp. 59-72
    • Fabarius, A.1    Hehlmann, R.2    Duesberg, P.H.3
  • 75
    • 57349085411 scopus 로고    scopus 로고
    • Li R, Rasnick D, Duesberg P: Correspondence re: D Zimonjic et al. Derivation of human tumor cells in vitro without widespread genomic instability. Cancer Res, 2001; 61: 8838-44, Cancer Res 2002; 62: 6345-48, author reply 6348-49
    • Li R, Rasnick D, Duesberg P: Correspondence re: D Zimonjic et al. Derivation of human tumor cells in vitro without widespread genomic instability. Cancer Res, 2001; 61: 8838-44, Cancer Res 2002; 62: 6345-48, author reply 6348-49
  • 76
    • 0037076325 scopus 로고    scopus 로고
    • Specific aneusomies in Chinese hamster cells at different stages of neoplastic transformation, initiated by nitrosomethylurea
    • Fabarius A, Willer A, Yerganian G et al: Specific aneusomies in Chinese hamster cells at different stages of neoplastic transformation, initiated by nitrosomethylurea. Proc Natl Acad Sci, 2002; 99: 6778-83
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 6778-6783
    • Fabarius, A.1    Willer, A.2    Yerganian, G.3
  • 77
    • 0037752456 scopus 로고    scopus 로고
    • Aneuploidy versus gene mutation as cause of cancer
    • Duesberg P, Stindl R, Li RH et al: Aneuploidy versus gene mutation as cause of cancer. Curr Sci, 2001; 81: 490-500
    • (2001) Curr Sci , vol.81 , pp. 490-500
    • Duesberg, P.1    Stindl, R.2    Li, R.H.3
  • 79
    • 85078507894 scopus 로고    scopus 로고
    • Multistep carcinogenesis: A chain reaction of aneuploidizations
    • Duesberg P, Li R: Multistep carcinogenesis: a chain reaction of aneuploidizations. Cell Cycle, 2003; 2: 202-10
    • (2003) Cell Cycle , vol.2 , pp. 202-210
    • Duesberg, P.1    Li, R.2
  • 80
    • 11844262086 scopus 로고    scopus 로고
    • Does aneuploidy or mutation start cancer?
    • Duesberg P: Does aneuploidy or mutation start cancer? Science, 2004; 307(5706): 41
    • (2004) Science , vol.307 , Issue.5706 , pp. 41
    • Duesberg, P.1
  • 81
    • 0033564230 scopus 로고    scopus 로고
    • How aneuploidy affects metabolic control and causes cancer
    • Rasnick D, Duesberg PH: How aneuploidy affects metabolic control and causes cancer. Biochem J, 1999; 340: 621-30
    • (1999) Biochem J , vol.340 , pp. 621-630
    • Rasnick, D.1    Duesberg, P.H.2
  • 82
    • 0034040855 scopus 로고    scopus 로고
    • Aneuploidy precedes, and segregates with chemical carcinogenesis
    • Duesberg P, Li R, Rasnick D et al: Aneuploidy precedes, and segregates with chemical carcinogenesis. Cancer Genet Cytogenet, 2000; 119: 83-93
    • (2000) Cancer Genet Cytogenet , vol.119 , pp. 83-93
    • Duesberg, P.1    Li, R.2    Rasnick, D.3
  • 83
    • 13744250510 scopus 로고    scopus 로고
    • Which came first? Studies clarify role of aneuploidy in cancer
    • Hede K: Which came first? Studies clarify role of aneuploidy in cancer. J Natl Cancer Inst, 2005; 97(2): 87-89
    • (2005) J Natl Cancer Inst , vol.97 , Issue.2 , pp. 87-89
    • Hede, K.1
  • 84
    • 0036708499 scopus 로고    scopus 로고
    • Functional inactivation of pRB results in aneuploid mammalian cells after release from a mitotic block
    • Lentini L, Pipitone L, Di Leonardo A: Functional inactivation of pRB results in aneuploid mammalian cells after release from a mitotic block. Neoplasia, 2002; 4(5): 380-87
    • (2002) Neoplasia , vol.4 , Issue.5 , pp. 380-387
    • Lentini, L.1    Pipitone, L.2    Di Leonardo, A.3
  • 85
    • 4043093341 scopus 로고    scopus 로고
    • Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control
    • Hernando E, Nahle Z, Juan G et al: Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control. Nature, 2004; 430(7001): 797-802
    • (2004) Nature , vol.430 , Issue.7001 , pp. 797-802
    • Hernando, E.1    Nahle, Z.2    Juan, G.3
  • 86
    • 0033594469 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells
    • Matsumoto Y, Hayashi K: Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells. Curr Biol, 1999; 8: 429-32
    • (1999) Curr Biol , vol.8 , pp. 429-432
    • Matsumoto, Y.1    Hayashi, K.2
  • 87
    • 0033145516 scopus 로고    scopus 로고
    • Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A
    • Meraldi P, Lukas J, Fry AM et al: Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A. Nat Cell Biol, 1999; 2: 88-93
    • (1999) Nat Cell Biol , vol.2 , pp. 88-93
    • Meraldi, P.1    Lukas, J.2    Fry, A.M.3
  • 89
    • 33750220492 scopus 로고    scopus 로고
    • RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts
    • Iovino F, Lentini L, Amato A, Di Leonardo A: RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts. Mol Cancer, 2006; 5: 38
    • (2006) Mol Cancer , vol.5 , pp. 38
    • Iovino, F.1    Lentini, L.2    Amato, A.3    Di Leonardo, A.4
  • 90
    • 8844286090 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitor indirubin-30-oxime selectively inhibits human papillomavirus type 16 E7-induced numerical centrosome anomalies
    • Duensing S, Duensing A, Lee DC et al: Cyclin-dependent kinase inhibitor indirubin-30-oxime selectively inhibits human papillomavirus type 16 E7-induced numerical centrosome anomalies. Oncogene, 2004; 23(50): 8206-15
    • (2004) Oncogene , vol.23 , Issue.50 , pp. 8206-8215
    • Duensing, S.1    Duensing, A.2    Lee, D.C.3
  • 91
    • 57349157519 scopus 로고    scopus 로고
    • http://ghr.nlm.nih.gov/condition=Rb
  • 92
    • 57349126588 scopus 로고    scopus 로고
    • http://www.ncbi.nlm.nih.gov/sites/entrez
  • 93
    • 34249004558 scopus 로고    scopus 로고
    • One hit, two hits, three hits, more? Genomic changes in the development of Rb
    • Corson TW, Gallie BL: One hit, two hits, three hits, more? Genomic changes in the development of Rb. Genes Chromosomes Cancer, 2007; 46(7): 617-34
    • (2007) Genes Chromosomes Cancer , vol.46 , Issue.7 , pp. 617-634
    • Corson, T.W.1    Gallie, B.L.2
  • 94
    • 57349152743 scopus 로고    scopus 로고
    • Insight' into Molecular Genetic Testing in Rb
    • Joseph B, Kumaramanickavel B: 'Insight' into Molecular Genetic Testing in Rb Int J Hum Genet, 2007; 7(1): 23-28
    • (2007) Int J Hum Genet , vol.7 , Issue.1 , pp. 23-28
    • Joseph, B.1    Kumaramanickavel, B.2
  • 95
    • 0030822570 scopus 로고    scopus 로고
    • Predictive Testing for Rb Comes of Age
    • Gallie BL: Predictive Testing for Rb Comes of Age. Am J Hum Genet, 1997; 61: 279-81
    • (1997) Am J Hum Genet , vol.61 , pp. 279-281
    • Gallie, B.L.1
  • 96
    • 0037322272 scopus 로고    scopus 로고
    • Sensitive and efficient detection of RB1 gene mutations enhances care for families with Rb
    • Richter S, Vandezande K, Chen N et al: Sensitive and efficient detection of RB1 gene mutations enhances care for families with Rb. Am J Hum Genet, 2003; 72(2): 253-69
    • (2003) Am J Hum Genet , vol.72 , Issue.2 , pp. 253-269
    • Richter, S.1    Vandezande, K.2    Chen, N.3
  • 97
    • 35648981872 scopus 로고    scopus 로고
    • Global issues and opportunities for optimized Rb care
    • Gallie BL, Zhao J, Vandezande K et al: Global issues and opportunities for optimized Rb care. Pediatr Blood Cancer, 2007; 49(Suppl.7): 1083-90
    • (2007) Pediatr Blood Cancer , vol.49 , Issue.SUPPL.7 , pp. 1083-1090
    • Gallie, B.L.1    Zhao, J.2    Vandezande, K.3
  • 98
    • 38149091915 scopus 로고    scopus 로고
    • Genetic testing and tumor surveillance for children with cancer predisposition syndromes
    • Rao A, Rothman J, Nichols KE: Genetic testing and tumor surveillance for children with cancer predisposition syndromes. Curr Opin Pediatr, 2008; 20(1): 1-7
    • (2008) Curr Opin Pediatr , vol.20 , Issue.1 , pp. 1-7
    • Rao, A.1    Rothman, J.2    Nichols, K.E.3
  • 99
    • 57349135021 scopus 로고    scopus 로고
    • http://www.accessexcellence.org/AE/AEPC/NIH/gene16.php
  • 100
    • 0038501057 scopus 로고    scopus 로고
    • American Society of Clinical Oncology Policy Statement Update: Genetic Testing for Cancer Susceptibility
    • American Society for Clinical Oncology
    • American Society for Clinical Oncology: American Society of Clinical Oncology Policy Statement Update: Genetic Testing for Cancer Susceptibility. J Clin Oncol, 2003; 21(12): 1-10
    • (2003) J Clin Oncol , vol.21 , Issue.12 , pp. 1-10
  • 101
  • 102
    • 84878259366 scopus 로고    scopus 로고
    • Murphree L: Local therapy, brachytherapy and enucleation. In: Singh A, D'Amato B, Pe'er J, Murphree L, Perry J: Clinical Ophthalmic Oncology Saunders - Elsevier, 2007; 454-61
    • Murphree L: Local therapy, brachytherapy and enucleation. In: Singh A, D'Amato B, Pe'er J, Murphree L, Perry J: Clinical Ophthalmic Oncology Saunders - Elsevier, 2007; 454-61
  • 103
    • 58349121784 scopus 로고    scopus 로고
    • Merchant TE: Teletherapy: indications, risks, and new delivery options. In: Singh A, D'Amato B, Pe'er J, Murphree L, Perry J: Clinical Ophthalmic Oncology Saunders - Elsevier, 2007; 462-67
    • Merchant TE: Teletherapy: indications, risks, and new delivery options. In: Singh A, D'Amato B, Pe'er J, Murphree L, Perry J: Clinical Ophthalmic Oncology Saunders - Elsevier, 2007; 462-67
  • 104
    • 57349184962 scopus 로고    scopus 로고
    • http://www.orpha.net/consor/cgi-bin/index.php?lng=EN
  • 105
    • 57349114444 scopus 로고    scopus 로고
    • http://www.virusmyth.net/aids/data/drstate.htm


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.