메뉴 건너뛰기




Volumn 6, Issue , 2005, Pages 1-14

A personal sixty-year tour of genetics and medicine

Author keywords

Cancer; Genetic chaos; Two hits

Indexed keywords

CANCER; CYTOGENETICS; GENETIC DISORDER; GENETIC SELECTION; INBORN ERROR OF METABOLISM; INCIDENCE; MEDICAL GENETICS; MOLECULAR BIOLOGY; REVIEW; VIROLOGY;

EID: 25844499158     PISSN: 15278204     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.genom.6.080604.162320     Document Type: Review
Times cited : (15)

References (53)
  • 1
    • 0014964654 scopus 로고
    • RNA-dependent DNA polymerase in virions of RNA tumour viruses
    • Baltimore D. 1970. RNA-dependent DNA polymerase in virions of RNA tumour viruses. Nature 226:1209-11
    • (1970) Nature , vol.226 , pp. 1209-1211
    • Baltimore, D.1
  • 2
    • 0020679049 scopus 로고
    • Patient with 13 chromosome deletion: Evidence that the retinoblastoma gene is a recessive cancer gene
    • Benedict WF, Murphree AL, Banerjee A, Spina CA, Sparkes MC, et al. 1983. Patient with 13 chromosome deletion: evidence that the retinoblastoma gene is a recessive cancer gene. Science 219:973-75
    • (1983) Science , vol.219 , pp. 973-975
    • Benedict, W.F.1    Murphree, A.L.2    Banerjee, A.3    Spina, C.A.4    Sparkes, M.C.5
  • 3
    • 25844493684 scopus 로고
    • Continuing metabolism of nitrogen in animals
    • Borsook H, Keighley GL. 1935. Continuing metabolism of nitrogen in animals. Proc. R. Soc. London 118:488-521
    • (1935) Proc. R. Soc. London , vol.118 , pp. 488-521
    • Borsook, H.1    Keighley, G.L.2
  • 4
    • 36949088975 scopus 로고
    • An unstable intermediate carrying information from genes to ribosomes for protein synthesis
    • Brenner S, Jacob F, Meselson M. 1961. An unstable intermediate carrying information from genes to ribosomes for protein synthesis. Nature 190:576-81
    • (1961) Nature , vol.190 , pp. 576-581
    • Brenner, S.1    Jacob, F.2    Meselson, M.3
  • 5
    • 0020518746 scopus 로고
    • Expression of recessive alleles by chromosomal mechanisms in retinoblastoma
    • Cavenee WK, Dryja TP, Phillips RA, Benedict WF, Godbout R, et al. 1983. Expression of recessive alleles by chromosomal mechanisms in retinoblastoma. Nature 305:779-84
    • (1983) Nature , vol.305 , pp. 779-784
    • Cavenee, W.K.1    Dryja, T.P.2    Phillips, R.A.3    Benedict, W.F.4    Godbout, R.5
  • 7
    • 0001011456 scopus 로고
    • A dominant gene for renal adenomas in the rat
    • Eker R, Mossige J. 1961. A dominant gene for renal adenomas in the rat. Nature 189:858-59
    • (1961) Nature , vol.189 , pp. 858-859
    • Eker, R.1    Mossige, J.2
  • 9
    • 0017060019 scopus 로고
    • Sporadic bilateral retinoblastoma and 13q-chromosomal deletion
    • Francke U, Kung F. 1976. Sporadic bilateral retinoblastoma and 13q-chromosomal deletion. Med. Pediatr. Oncol. 2:379-85
    • (1976) Med. Pediatr. Oncol. , vol.2 , pp. 379-385
    • Francke, U.1    Kung, F.2
  • 10
    • 0022506980 scopus 로고
    • A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
    • Friend SH, Bernards R, Rogelj S, Weinberg RA, Rapaport JM, et al. 1986. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 323:643-46
    • (1986) Nature , vol.323 , pp. 643-646
    • Friend, S.H.1    Bernards, R.2    Rogelj, S.3    Weinberg, R.A.4    Rapaport, J.M.5
  • 12
    • 0020512716 scopus 로고
    • Somatic inactivation of genes on chromosome 13 is a common event in retinoblastoma
    • Godbout R, Dryja TP, Squire J, Gallie BL, Phillips RA. 1983. Somatic inactivation of genes on chromosome 13 is a common event in retinoblastoma. Nature 304:451-53
    • (1983) Nature , vol.304 , pp. 451-453
    • Godbout, R.1    Dryja, T.P.2    Squire, J.3    Gallie, B.L.4    Phillips, R.A.5
  • 13
    • 36949085892 scopus 로고
    • Unstable ribonucleic acid revealed by pulse labelling of Escherichia coli
    • Gros F, Hiatt H, Gilbert W, Kurland CG, Risebrough RW, et al. 1961. Unstable ribonucleic acid revealed by pulse labelling of Escherichia coli. Nature 190:581-85
    • (1961) Nature , vol.190 , pp. 581-585
    • Gros, F.1    Hiatt, H.2    Gilbert, W.3    Kurland, C.G.4    Risebrough, R.W.5
  • 14
    • 0013818190 scopus 로고
    • Absence of detrimental effect of the carrier state for the cystic fibrosis gene
    • Hallett WY, Knudson AG, Massey FJ. 1965. Absence of detrimental effect of the carrier state for the cystic fibrosis gene. Am. Rev. Respir. Dis. 92:714-24
    • (1965) Am. Rev. Respir. Dis. , vol.92 , pp. 714-724
    • Hallett, W.Y.1    Knudson, A.G.2    Massey, F.J.3
  • 15
    • 0027458433 scopus 로고
    • Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer
    • Hino O, Klein-Szanto AJ, Freed JJ, Testa JR, Brown DQ, et al. 1993. Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer. Proc. Natl. Acad. Sci. USA 90:327-31
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 327-331
    • Hino, O.1    Klein-Szanto, A.J.2    Freed, J.J.3    Testa, J.R.4    Brown, D.Q.5
  • 16
    • 36949092449 scopus 로고
    • Allelomorphism and the chemical differences of the human haemoglobins A, S and C
    • Hunt JA, Ingram VM. 1958. Allelomorphism and the chemical differences of the human haemoglobins A, S and C. Nature 181:1062-63
    • (1958) Nature , vol.181 , pp. 1062-1063
    • Hunt, J.A.1    Ingram, V.M.2
  • 17
    • 54249116230 scopus 로고
    • Genetic regulatory mechanisms in the synthesis of proteins
    • Jacob F, Monod J. 1961. Genetic regulatory mechanisms in the synthesis of proteins. J. Mol. Biol. 3:318-56
    • (1961) J. Mol. Biol. , vol.3 , pp. 318-356
    • Jacob, F.1    Monod, J.2
  • 18
    • 0035233041 scopus 로고    scopus 로고
    • Screening and prevention in Tay-Sachs disease: Origins, update, and impact
    • Kaback MM. 2001. Screening and prevention in Tay-Sachs disease: origins, update, and impact. Adv. Genet. 44:253-65
    • (2001) Adv. Genet. , vol.44 , pp. 253-265
    • Kaback, M.M.1
  • 19
    • 25844442468 scopus 로고
    • Mixed adrenal disease of infancy
    • Knudson AG. 1951. Mixed adrenal disease of infancy. J. Pediatr. 39:408-23
    • (1951) J. Pediatr. , vol.39 , pp. 408-423
    • Knudson, A.G.1
  • 20
    • 25844479854 scopus 로고
    • Inborn errors of sphingolipid metabolism
    • Knudson AG. 1961. Inborn errors of sphingolipid metabolism. Am. J. Clin. Nutr. 9:55-62
    • (1961) Am. J. Clin. Nutr. , vol.9 , pp. 55-62
    • Knudson, A.G.1
  • 21
    • 0006414382 scopus 로고
    • Ethnic differences in childhood leukemia as revealed by a study of antecedent variables
    • Knudson AG. 1965. Ethnic differences in childhood leukemia as revealed by a study of antecedent variables. Cancer 18:815-18
    • (1965) Cancer , vol.18 , pp. 815-818
    • Knudson, A.G.1
  • 23
    • 0006454239 scopus 로고
    • Congenital viral infection and human disease
    • Knudson AG. 1966. Congenital viral infection and human disease. Am. Nat. 100:162-64
    • (1966) Am. Nat. , vol.100 , pp. 162-164
    • Knudson, A.G.1
  • 24
    • 0015043748 scopus 로고
    • Mutation and cancer: Statistical study of retinoblastoma
    • Knudson AG. 1971. Mutation and cancer: statistical study of retinoblastoma. Proc. Natl. Acad. Sci. USA 68:820-23
    • (1971) Proc. Natl. Acad. Sci. USA , vol.68 , pp. 820-823
    • Knudson, A.G.1
  • 25
    • 0015549517 scopus 로고
    • Founder effect in Tay-Sachs disease
    • Knudson AG. 1973. Founder effect in Tay-Sachs disease. Am. J. Hum. Genet. 25:108
    • (1973) Am. J. Hum. Genet. , vol.25 , pp. 108
    • Knudson, A.G.1
  • 26
    • 0017819319 scopus 로고
    • Retinoblastoma: A prototypic hereditary neoplasm
    • Knudson AG. 1978. Retinoblastoma: a prototypic hereditary neoplasm. Semin. Oncol. 5:57-60
    • (1978) Semin. Oncol. , vol.5 , pp. 57-60
    • Knudson, A.G.1
  • 27
    • 0018735226 scopus 로고
    • Presidential address. Our load of mutations and its burden of disease
    • Knudson AG. 1979. Presidential address. Our load of mutations and its burden of disease. Am. J. Hum. Genet. 31:401-13
    • (1979) Am. J. Hum. Genet. , vol.31 , pp. 401-413
    • Knudson, A.G.1
  • 28
    • 0014181786 scopus 로고
    • Transient inhibition of avian myeloblastosis virus reproduction by amethopterin and fluorodeoxyuridine
    • Knudson AG, Brodetsky AM, Baluda MA. 1967. Transient inhibition of avian myeloblastosis virus reproduction by amethopterin and fluorodeoxyuridine. J. Virol. 1:1150-57
    • (1967) J. Virol. , vol.1 , pp. 1150-1157
    • Knudson, A.G.1    Brodetsky, A.M.2    Baluda, M.A.3
  • 30
    • 0007767637 scopus 로고
    • Genetics of the sphingolipidoses
    • ed. SM Aronson, BW Volk, New York: Academic
    • Knudson AG, Kaplan WD. 1962. Genetics of the sphingolipidoses. In Cerebral Sphingolipidoses, ed. SM Aronson, BW Volk, pp. 395-411. New York: Academic
    • (1962) Cerebral Sphingolipidoses , pp. 395-411
    • Knudson, A.G.1    Kaplan, W.D.2
  • 32
    • 25844522786 scopus 로고
    • Molecular genetics and disease resistance
    • ed. A Rich, N Davidson, San Francisco: Freeman
    • Knudson AG, Owen RD. 1968. Molecular genetics and disease resistance. In Structural Chemistry and Molecular Biology, ed. A Rich, N Davidson, pp. 281-84. San Francisco: Freeman
    • (1968) Structural Chemistry and Molecular Biology , pp. 281-284
    • Knudson, A.G.1    Owen, R.D.2
  • 33
    • 25844476209 scopus 로고
    • Hypervitaminosis A. A review with a discussion of vitamin A
    • Knudson AG, Rothman PE. 1953. Hypervitaminosis A. A review with a discussion of vitamin A. Am. J. Dis. Child 85:316-34
    • (1953) Am. J. Dis. Child , vol.85 , pp. 316-334
    • Knudson, A.G.1    Rothman, P.E.2
  • 34
    • 0015295131 scopus 로고
    • Mutation and cancer: A model for Wilms' tumor of the kidney
    • Knudson AG, Strong LC. 1972. Mutation and cancer: a model for Wilms' tumor of the kidney. J. Natl. Cancer Inst. 48:313-24
    • (1972) J. Natl. Cancer Inst. , vol.48 , pp. 313-324
    • Knudson, A.G.1    Strong, L.C.2
  • 35
    • 0015402175 scopus 로고
    • Mutation and cancer: Neuroblastoma and pheochromocytoma
    • Knudson AG, Strong LC. 1972. Mutation and cancer: neuroblastoma and pheochromocytoma. Am. J. Hum. Genet. 24:514-32
    • (1972) Am. J. Hum. Genet. , vol.24 , pp. 514-532
    • Knudson, A.G.1    Strong, L.C.2
  • 36
    • 0014086491 scopus 로고
    • On the selective advantage of cystic fibrosis heterozygotes
    • Knudson AG, Wayne L, Hallett WY. 1967. On the selective advantage of cystic fibrosis heterozygotes. Am. J. Hum. Genet. 19:388-92
    • (1967) Am. J. Hum. Genet. , vol.19 , pp. 388-392
    • Knudson, A.G.1    Wayne, L.2    Hallett, W.Y.3
  • 37
    • 0028830856 scopus 로고
    • A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer
    • Kobayashi T, Hirayama Y, Kobayashi E, Kubo Y, Hino O. 1995. A germline insertion in the tuberous sclerosis (Tsc2) gene gives rise to the Eker rat model of dominantly inherited cancer. Nat. Genet. 9:70-74
    • (1995) Nat. Genet. , vol.9 , pp. 70-74
    • Kobayashi, T.1    Hirayama, Y.2    Kobayashi, E.3    Kubo, Y.4    Hino, O.5
  • 38
    • 0344372054 scopus 로고
    • Hemoglobin synthesis in rabbit reticulocytes in vitro
    • Kruh J, Borsook H. 1956. Hemoglobin synthesis in rabbit reticulocytes in vitro. J. Biol. Chem. 220:905-15
    • (1956) J. Biol. Chem. , vol.220 , pp. 905-915
    • Kruh, J.1    Borsook, H.2
  • 39
    • 70449245071 scopus 로고
    • Etude des chromosomes somatiques de neuf enfants mongoliens
    • Lejeune J, Gautier M, Turpin R. 1959. Etude des chromosomes somatiques de neuf enfants mongoliens. C. Rend. Acad. Sc. 248:1721-22
    • (1959) C. Rend. Acad. Sc. , vol.248 , pp. 1721-1722
    • Lejeune, J.1    Gautier, M.2    Turpin, R.3
  • 40
    • 0000286732 scopus 로고
    • A minute chromosome in human chronic granulocytic leukemia
    • Nowell P, Hungerford D. 1960. A minute chromosome in human chronic granulocytic leukemia. Science 132:1497
    • (1960) Science , vol.132 , pp. 1497
    • Nowell, P.1    Hungerford, D.2
  • 41
    • 0014678521 scopus 로고
    • Tay-Sachs disease: Generalized absence of a beta-D-N-acetylhexosaminidase component
    • Okada S, O' Brien JS. 1969. Tay-Sachs disease: generalized absence of a beta-D-N-acetylhexosaminidase component. Science 165:698-700
    • (1969) Science , vol.165 , pp. 698-700
    • Okada, S.1    O'Brien, J.S.2
  • 42
    • 0000658958 scopus 로고
    • Immunogenetic consequences of vascular anastomoses between bovine twins
    • Owen RD. 1945. Immunogenetic consequences of vascular anastomoses between bovine twins. Science 102:400-1
    • (1945) Science , vol.102 , pp. 400-401
    • Owen, R.D.1
  • 43
    • 0000192486 scopus 로고
    • Sickle cell anemia, a molecular disease
    • Pauling L, Itano HA. 1949. Sickle cell anemia, a molecular disease. Science 110:543-48
    • (1949) Science , vol.110 , pp. 543-548
    • Pauling, L.1    Itano, H.A.2
  • 44
    • 0032430266 scopus 로고    scopus 로고
    • Loss of function of the tuberous sclerosis 2 tumor suppressor gene results in embryonic lethality characterized by disrupted neuroepithelial growth and development
    • Rennebeck G, Kleymenova EV, Anderson R, Yeung RS, Artzt K, et al. 1998. Loss of function of the tuberous sclerosis 2 tumor suppressor gene results in embryonic lethality characterized by disrupted neuroepithelial growth and development. Proc. Natl. Acad. Sci. USA 95:15629-34
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 15629-15634
    • Rennebeck, G.1    Kleymenova, E.V.2    Anderson, R.3    Yeung, R.S.4    Artzt, K.5
  • 45
    • 84979948588 scopus 로고
    • A sarcoma of the fowl transmissible by an agent separable from the tumor cells
    • Rous P. 1911. A sarcoma of the fowl transmissible by an agent separable from the tumor cells. J. Exp. Med. 13:397-411
    • (1911) J. Exp. Med. , vol.13 , pp. 397-411
    • Rous, P.1
  • 48
    • 0019190556 scopus 로고
    • Regional assignment of genes for human esterase D and retinoblastoma to chromosome band 13q14
    • Sparkes RS, Sparkes MC, Wilson MG, Towner JW, Benedict W, et al. 1980. Regional assignment of genes for human esterase D and retinoblastoma to chromosome band 13q14. Science 208:1042-44
    • (1980) Science , vol.208 , pp. 1042-1044
    • Sparkes, R.S.1    Sparkes, M.C.2    Wilson, M.G.3    Towner, J.W.4    Benedict, W.5
  • 49
    • 0017250977 scopus 로고
    • DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA
    • Stehelin D, Varmus HE, Bishop JM, Vogt PK. 1976. DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature 260:170-73
    • (1976) Nature , vol.260 , pp. 170-173
    • Stehelin, D.1    Varmus, H.E.2    Bishop, J.M.3    Vogt, P.K.4
  • 50
    • 0014964695 scopus 로고
    • RNA-dependent DNA polymerase in virions of Rous sarcoma virus
    • Temin HM, Mizutani S. 1970. RNA-dependent DNA polymerase in virions of Rous sarcoma virus. Nature 226:1211-13
    • (1970) Nature , vol.226 , pp. 1211-1213
    • Temin, H.M.1    Mizutani, S.2
  • 51
    • 0034607243 scopus 로고    scopus 로고
    • National Cancer Institute Workshop Report: The phakomatoses revisited
    • Tucker M, Goldstein A, Dean M, Knudson A. 2000. National Cancer Institute Workshop Report: the phakomatoses revisited. J. Natl. Cancer Inst. 92:530-33
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 530-533
    • Tucker, M.1    Goldstein, A.2    Dean, M.3    Knudson, A.4
  • 52
    • 0242300088 scopus 로고    scopus 로고
    • Endogenous DNA double-strand breaks: Production, fidelity of repair, and induction of cancer
    • Vilenchik MM, Knudson AG. 2003. Endogenous DNA double-strand breaks: production, fidelity of repair, and induction of cancer. Proc. Natl. Acad. Sci. USA 100:12871-76
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 12871-12876
    • Vilenchik, M.M.1    Knudson, A.G.2
  • 53
    • 0027996238 scopus 로고
    • Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene
    • Yeung RS, Xiao GH, Jin F, Lee WC, Testa JR, et al. 1994. Predisposition to renal carcinoma in the Eker rat is determined by germ-line mutation of the tuberous sclerosis 2 (TSC2) gene. Proc. Natl. Acad. Sci. USA 91:11413-16
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 11413-11416
    • Yeung, R.S.1    Xiao, G.H.2    Jin, F.3    Lee, W.C.4    Testa, J.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.