Development of novel G-protein-coupled receptor 54 agonists with resistance to degradation by matrix metalloproteinase

Journal of Medicinal Chemistry

Volumn 51, Issue 23, 2008, Pages 7645-7649

  Tomita, Kenji ^a   Oishi, Shinya ^a   Ohno, Hiroaki ^a   Peiper, Stephen C ^b   Fujii, Nobutaka ^a  

^a KYOTO UNIVERSITY   (Japan)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 FLUOROBENZOYLPHENYLALANYLGLYCYLLEUCYLARGINYLTRYPTOPHANAMIDE; G PROTEIN COUPLED RECEPTOR 54; G PROTEIN COUPLED RECEPTOR 54 STIMULATING AGENT; GELATINASE B; KISSPEPTIN; KISSPEPTIN 10; PENTAPEPTIDE; UNCLASSIFIED DRUG;

AGONIST; AMINO ACID SEQUENCE; ARTICLE; DRUG DEGRADATION; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; IC 50; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

BINDING SITES; DIPEPTIDES; DRUG DESIGN; LIGANDS; MATRIX METALLOPROTEINASES; MOLECULAR CONFORMATION; RECEPTORS, G-PROTEIN-COUPLED; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS;

EID: 57349191049     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm800930w     Document Type: Article

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