Structure-activity relationship study on small peptidic GPR54 agonists

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 22, 2006, Pages 7595-7603

  Tomita, Kenji ^a   Niida, Ayumu ^a   Oishi, Shinya ^a   Ohno, Hiroaki ^a   Cluzeau, Jérôme ^a   Navenot, Jean Marc ^b   Wang, Zi xuan ^b   Peiper, Stephen C ^b   Fujii, Nobutaka ^a  

^a KYOTO UNIVERSITY   (Japan)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

GPR54; Kisspeptin; Metastin; RW amide; Structure activity relationship study

Indexed keywords

4 (GUANIDINOMETHYL)BENZOIC ACID DEXTRO PHENYLGLYCYLLEUCYLARGINYLTRYPTOPHANAMIDE; 4 (GUANIDINOMETHYL)BENZOIC ACID PHENYL DEXTRO GLYCYLLEUCYLARGINYLTRYPTOPHANAMIDE; 4 (GUANIDINOMETHYL)BENZOIC ACID PHENYLALANYLGLYCYLLEUCYLARGINYLTRPYTOPHANAMIDE; 4 (GUANIDINOMETHYL)BENZOIC ACID PHENYLALANYLLEUCYLARGINYLTRYPTOPHANAMIDE; 4 (GUANIDINOMETHYL)BENZOIC ACID PHENYLGLYCYLALANYLARGINYLTRYPTOPHANAMIDE; 4 (GUANIDINOMETHYL)BENZOIC ACID PHENYLGLYCYLLEUCYL DEXTRO ARGINYLTRYPTOPHANAMIDE; 4 (GUANIDINOMETHYL)BENZOIC ACID PHENYLGLYCYLLEUCYLALANYLTRYPTOPHANAMIDE; 4 (GUANIDINOMETHYL)BENZOIC ACID PHENYLGLYCYLLEUCYLARGINYL 3 (2 NAPHTHYL)ALANINAMIDE; 4 (GUANIDINOMETHYL)BENZOIC ACID PHENYLGLYCYLLEUCYLARGINYL DEXTRO TRYPTOPHANAMIDE; 4 (GUANIDINOMETHYL)BENZOIC ACID PHENYLGLYCYLLEUCYLARGINYLALANINAMIDE; 4 (GUANIDINOMETHYL)BENZOIC ACID PHENYLGLYCYLLEUCYLARGINYLPHENYLALANINAMIDE; 4 (GUANIDINOMETHYL)BENZOIC ACID PHENYLGLYCYLLEUCYLARGINYLTRYPTOPHANAMIDE; 4 (GUANIDINOMETHYL)BENZOIC ACID PHENYLGLYCYLLEUCYLARGINYLTYROSINAMIDE; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 54; N,N BIS(2 PICOLYL) 4 (AMINOMETHYL)BENZOIC ACID ALANYLLEUCYLARGINYLTRYPTOPHANAMIDE; N,N BIS(2 PICOLYL) 4 (AMINOMETHYL)BENZOIC ACID DEXTRO PHENYLGLYCYLLEUCYLARGINYLTRYPTOPHANAMIDE; N,N BIS(2 PICOLYL) 4 (AMINOMETHYL)BENZOIC ACID PHENYL DEXTRO GLYCYLLEUCYLARGINYLTRYPTOPHANAMIDE; N,N BIS(2 PICOLYL) 4 (AMINOMETHYL)BENZOIC ACID PHENYLALANYLGLYCYLLEUCYLARGINYLTRPYTOPHANAMIDE; N,N BIS(2 PICOLYL) 4 (AMINOMETHYL)BENZOIC ACID PHENYLGLYCYLALANYLARGINYLTRYPTOPHANAMIDE; N,N BIS(2 PICOLYL) 4 (AMINOMETHYL)BENZOIC ACID PHENYLGLYCYLLEUCYLARGINYL DEXTRO TRYPTOPHANAMIDE; N,N BIS(2 PICOLYL) 4 (AMINOMETHYL)BENZOIC ACID PHENYLGLYCYLLEUCYLARGINYLALANINAMIDE; N,N BIS(2 PICOLYL) 4 (AMINOMETHYL)BENZOIC ACID PHENYLGLYCYLLEUCYLARGINYLALANYLTRYPTOPHANAMIDE; N,N BIS(2 PICOLYL) 4 (AMINOMETHYL)BENZOIC ACID PHENYLGLYCYLLEUCYLARGINYLTRYPTOPHANAMIDE; PENTAPEPTIDE; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; DRUG POTENCY; PEPTIDE ANALYSIS; STRUCTURE ACTIVITY RELATION;

ALKYLATION; AMIDES; ANIMALS; CHO CELLS; CRICETINAE; HYDRAZINES; MOLECULAR STRUCTURE; PEPTIDES; RECEPTORS, G-PROTEIN-COUPLED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33749251813     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.07.009     Document Type: Article

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