-
1
-
-
33745823159
-
The ATM-mediated DNA-damage response: taking shape
-
Shiloh Y. The ATM-mediated DNA-damage response: taking shape. Trends Biochem. Sci. 31 (2006) 402-410
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 402-410
-
-
Shiloh, Y.1
-
2
-
-
35848967773
-
Causes and consequences of the DNA damage response
-
Nussenzweig A. Causes and consequences of the DNA damage response. Cell Cycle 6 (2007) 2339-2340
-
(2007)
Cell Cycle
, vol.6
, pp. 2339-2340
-
-
Nussenzweig, A.1
-
3
-
-
10944257674
-
Crosslinks and crosstalk: human cancer syndromes and DNA repair defects
-
Risinger M.A., and Groden J. Crosslinks and crosstalk: human cancer syndromes and DNA repair defects. Cancer Cell 6 (2004) 539-545
-
(2004)
Cancer Cell
, vol.6
, pp. 539-545
-
-
Risinger, M.A.1
Groden, J.2
-
4
-
-
9244251125
-
Cell-cycle checkpoints and cancer
-
Kastan M.B., and Bartek J. Cell-cycle checkpoints and cancer. Nature 432 (2004) 316-323
-
(2004)
Nature
, vol.432
, pp. 316-323
-
-
Kastan, M.B.1
Bartek, J.2
-
6
-
-
17244366865
-
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
-
Gorgoulis V.G., Vassiliou L.V., Karakaidos P., Zacharatos P., Kotsinas A., Liloglou T., et al. Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 434 (2005) 907-913
-
(2005)
Nature
, vol.434
, pp. 907-913
-
-
Gorgoulis, V.G.1
Vassiliou, L.V.2
Karakaidos, P.3
Zacharatos, P.4
Kotsinas, A.5
Liloglou, T.6
-
7
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
Bartkova J., Horejsi Z., Koed K., Kramer A., Tort F., Zieger K., et al. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 434 (2005) 864-870
-
(2005)
Nature
, vol.434
, pp. 864-870
-
-
Bartkova, J.1
Horejsi, Z.2
Koed, K.3
Kramer, A.4
Tort, F.5
Zieger, K.6
-
8
-
-
33845235459
-
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
-
Bartkova J., Rezaei N., Liontos M., Karakaidos P., Kletsas D., Issaeva N., et al. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 444 (2006) 633-637
-
(2006)
Nature
, vol.444
, pp. 633-637
-
-
Bartkova, J.1
Rezaei, N.2
Liontos, M.3
Karakaidos, P.4
Kletsas, D.5
Issaeva, N.6
-
9
-
-
33646757879
-
ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency
-
Cao L., Kim S., Xiao C., Wang R.H., Coumoul X., Wang X., et al. ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency. EMBO J. 25 (2006) 2167-2177
-
(2006)
EMBO J.
, vol.25
, pp. 2167-2177
-
-
Cao, L.1
Kim, S.2
Xiao, C.3
Wang, R.H.4
Coumoul, X.5
Wang, X.6
-
10
-
-
33644857012
-
Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism
-
Ayyanan A., Civenni G., Ciarloni L., Morel C., Mueller N., Lefort K., et al. Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism. Proc. Natl. Acad. Sci. USA 103 (2006) 3799-3804
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 3799-3804
-
-
Ayyanan, A.1
Civenni, G.2
Ciarloni, L.3
Morel, C.4
Mueller, N.5
Lefort, K.6
-
11
-
-
35548929551
-
Declining p53 function in the aging process: a possible mechanism for the increased tumor incidence in older populations
-
Feng Z., Hu W., Teresky A.K., Hernando E., Cordon-Cardo C., and Levine A.J. Declining p53 function in the aging process: a possible mechanism for the increased tumor incidence in older populations. Proc. Natl. Acad. Sci. USA 104 (2007) 16633-16638
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 16633-16638
-
-
Feng, Z.1
Hu, W.2
Teresky, A.K.3
Hernando, E.4
Cordon-Cardo, C.5
Levine, A.J.6
-
13
-
-
33847271255
-
Links between DNA double strand break repair and breast cancer: accumulating evidence from both familial and nonfamilial cases
-
Ralhan R., Kaur J., Kreienberg R., and Wiesmuller L. Links between DNA double strand break repair and breast cancer: accumulating evidence from both familial and nonfamilial cases. Cancer Lett. 248 (2007) 1-17
-
(2007)
Cancer Lett.
, vol.248
, pp. 1-17
-
-
Ralhan, R.1
Kaur, J.2
Kreienberg, R.3
Wiesmuller, L.4
-
14
-
-
33750975372
-
The role of estrogen in the initiation of breast cancer
-
Russo J., and Russo I.H. The role of estrogen in the initiation of breast cancer. J. Steroid Biochem. Mol. Biol. 102 (2006) 89-96
-
(2006)
J. Steroid Biochem. Mol. Biol.
, vol.102
, pp. 89-96
-
-
Russo, J.1
Russo, I.H.2
-
15
-
-
33749002551
-
Models of genetic susceptibility to breast cancer
-
Antoniou A.C., and Easton D.F. Models of genetic susceptibility to breast cancer. Oncogene 25 (2006) 5898-5905
-
(2006)
Oncogene
, vol.25
, pp. 5898-5905
-
-
Antoniou, A.C.1
Easton, D.F.2
-
16
-
-
34047201701
-
Association between common variation in 120 candidate genes and breast cancer risk
-
Pharoah P.D., Tyrer J., Dunning A.M., Easton D.F., and Ponder B.A. Association between common variation in 120 candidate genes and breast cancer risk. PLoS Genet. 3 (2007) e42
-
(2007)
PLoS Genet.
, vol.3
-
-
Pharoah, P.D.1
Tyrer, J.2
Dunning, A.M.3
Easton, D.F.4
Ponder, B.A.5
-
17
-
-
34250006413
-
Genome-wide association study identifies novel breast cancer susceptibility loci
-
Easton D.F., Pooley K.A., Dunning A.M., Pharoah P.D., Thompson D., Ballinger D.G., et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 447 (2007) 1087-1093
-
(2007)
Nature
, vol.447
, pp. 1087-1093
-
-
Easton, D.F.1
Pooley, K.A.2
Dunning, A.M.3
Pharoah, P.D.4
Thompson, D.5
Ballinger, D.G.6
-
18
-
-
57349179797
-
Haplotype patterns in cancer-related genes with long-range linkage disequilibrium: no evidence of association with breast cancer or positive selection
-
Ribas G., Milne R.L., Gonzalez-Neira A., and Benitez J. Haplotype patterns in cancer-related genes with long-range linkage disequilibrium: no evidence of association with breast cancer or positive selection. Eur. J. Hum. Genet. (2007)
-
(2007)
Eur. J. Hum. Genet.
-
-
Ribas, G.1
Milne, R.L.2
Gonzalez-Neira, A.3
Benitez, J.4
-
19
-
-
33845206567
-
Gene expression profiles do not consistently predict the clinical treatment response in locally advanced breast cancer
-
Sorlie T., Perou C.M., Fan C., Geisler S., Aas T., Nobel A., et al. Gene expression profiles do not consistently predict the clinical treatment response in locally advanced breast cancer. Mol. Cancer Ther. 5 (2006) 2914-2918
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 2914-2918
-
-
Sorlie, T.1
Perou, C.M.2
Fan, C.3
Geisler, S.4
Aas, T.5
Nobel, A.6
-
20
-
-
33748073782
-
Targeting the double-strand DNA break repair pathway as a therapeutic strategy
-
Lord C.J., Garrett M.D., and Ashworth A. Targeting the double-strand DNA break repair pathway as a therapeutic strategy. Clin. Cancer Res. 12 (2006) 4463-4468
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 4463-4468
-
-
Lord, C.J.1
Garrett, M.D.2
Ashworth, A.3
-
21
-
-
34250887474
-
Taking gene-expression profiling to the clinic: when will molecular signatures become relevant to patient care?
-
Sotiriou C., and Piccart M.J. Taking gene-expression profiling to the clinic: when will molecular signatures become relevant to patient care?. Nat. Rev. Cancer 7 (2007) 545-553
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 545-553
-
-
Sotiriou, C.1
Piccart, M.J.2
-
22
-
-
20444491228
-
P53 mutation profile of squamous cell carcinomas of the esophagus in Kashmir (India): a high-incidence area
-
Mir M.M., Dar N.A., Gochhait S., Zargar S.A., Ahangar A.G., and Bamezai R.N. P53 mutation profile of squamous cell carcinomas of the esophagus in Kashmir (India): a high-incidence area. Int. J. Cancer 116 (2005) 62-68
-
(2005)
Int. J. Cancer
, vol.116
, pp. 62-68
-
-
Mir, M.M.1
Dar, N.A.2
Gochhait, S.3
Zargar, S.A.4
Ahangar, A.G.5
Bamezai, R.N.6
-
23
-
-
40449093646
-
Implication of BRCA2 -26G > A 5′UTR polymorphism in susceptibility to sporadic breast cancer and its modulation by p53 codon 72Arg > Pro polymorphism
-
Gochhait S., Bukhari S.I., Bairwa N., Raish M., Gupta P., Husain S.A., et al. Implication of BRCA2 -26G > A 5′UTR polymorphism in susceptibility to sporadic breast cancer and its modulation by p53 codon 72Arg > Pro polymorphism. Breast Cancer Res. 9 (2007) R71
-
(2007)
Breast Cancer Res.
, vol.9
-
-
Gochhait, S.1
Bukhari, S.I.2
Bairwa, N.3
Raish, M.4
Gupta, P.5
Husain, S.A.6
-
24
-
-
33751568508
-
The cellular control of DNA double-strand breaks
-
Scott S.P., and Pandita T.K. The cellular control of DNA double-strand breaks. J. Cell. Biochem. (2006)
-
(2006)
J. Cell. Biochem.
-
-
Scott, S.P.1
Pandita, T.K.2
-
25
-
-
41149123600
-
The DNA damage signalling kinase ATM is aberrantly reduced or lost in BRCA1/BRCA2-deficient and ER/PR/ERBB2-triple-negative breast cancer
-
Tommiska J., Bartkova J., Heinonen M., Hautala L., Kilpivaara O., Eerola H., et al. The DNA damage signalling kinase ATM is aberrantly reduced or lost in BRCA1/BRCA2-deficient and ER/PR/ERBB2-triple-negative breast cancer. Oncogene (2007)
-
(2007)
Oncogene
-
-
Tommiska, J.1
Bartkova, J.2
Heinonen, M.3
Hautala, L.4
Kilpivaara, O.5
Eerola, H.6
-
26
-
-
33846971222
-
Transcriptional changes associated with breast cancer occur as normal human mammary epithelial cells overcome senescence barriers and become immortalized
-
Li Y., Pan J., Li J.L., Lee J.H., Tunkey C., Saraf K., et al. Transcriptional changes associated with breast cancer occur as normal human mammary epithelial cells overcome senescence barriers and become immortalized. Mol. Cancer 6 (2007) 7
-
(2007)
Mol. Cancer
, vol.6
, pp. 7
-
-
Li, Y.1
Pan, J.2
Li, J.L.3
Lee, J.H.4
Tunkey, C.5
Saraf, K.6
-
27
-
-
33748670457
-
The pathological response to DNA damage does not contribute to p53-mediated tumour suppression
-
Christophorou M.A., Ringshausen I., Finch A.J., Swigart L.B., and Evan G.I. The pathological response to DNA damage does not contribute to p53-mediated tumour suppression. Nature 443 (2006) 214-217
-
(2006)
Nature
, vol.443
, pp. 214-217
-
-
Christophorou, M.A.1
Ringshausen, I.2
Finch, A.J.3
Swigart, L.B.4
Evan, G.I.5
-
28
-
-
33748674375
-
Tumour biology: policing of oncogene activity by p53
-
Efeyan A., Garcia-Cao I., Herranz D., Velasco-Miguel S., and Serrano M. Tumour biology: policing of oncogene activity by p53. Nature 443 (2006) 159
-
(2006)
Nature
, vol.443
, pp. 159
-
-
Efeyan, A.1
Garcia-Cao, I.2
Herranz, D.3
Velasco-Miguel, S.4
Serrano, M.5
-
29
-
-
18344377030
-
The p53 pathway: positive and negative feedback loops
-
Harris S.L., and Levine A.J. The p53 pathway: positive and negative feedback loops. Oncogene 24 (2005) 2899-2908
-
(2005)
Oncogene
, vol.24
, pp. 2899-2908
-
-
Harris, S.L.1
Levine, A.J.2
-
30
-
-
34047216406
-
P53 alterations in human cancer: more questions than answers
-
Soussi T. P53 alterations in human cancer: more questions than answers. Oncogene 26 (2007) 2145-2156
-
(2007)
Oncogene
, vol.26
, pp. 2145-2156
-
-
Soussi, T.1
-
31
-
-
34247329362
-
P53 gain-of-function cancer mutants induce genetic instability by inactivating ATM
-
Song H., Hollstein M., and Xu Y. P53 gain-of-function cancer mutants induce genetic instability by inactivating ATM. Nat. Cell Biol. 9 (2007) 573-580
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 573-580
-
-
Song, H.1
Hollstein, M.2
Xu, Y.3
-
32
-
-
34547792817
-
A gene transcription signature associated with hormone independence in a subset of both breast and prostate cancers
-
Creighton C.J. A gene transcription signature associated with hormone independence in a subset of both breast and prostate cancers. BMC Genomics 8 (2007) 199
-
(2007)
BMC Genomics
, vol.8
, pp. 199
-
-
Creighton, C.J.1
-
33
-
-
35848949304
-
DNA damage response as an anti-cancer barrier: damage threshold and the concept of 'conditional haploinsufficiency'
-
Bartek J., Lukas J., and Bartkova J. DNA damage response as an anti-cancer barrier: damage threshold and the concept of 'conditional haploinsufficiency'. Cell Cycle 6 (2007) 2344-2347
-
(2007)
Cell Cycle
, vol.6
, pp. 2344-2347
-
-
Bartek, J.1
Lukas, J.2
Bartkova, J.3
-
34
-
-
0033119769
-
Comparative genomic hybridization of breast tumors stratified by histological grade reveals new insights into the biological progression of breast cancer
-
Roylance R., Gorman P., Harris W., Liebmann R., Barnes D., Hanby A., et al. Comparative genomic hybridization of breast tumors stratified by histological grade reveals new insights into the biological progression of breast cancer. Cancer Res. 59 (1999) 1433-1436
-
(1999)
Cancer Res.
, vol.59
, pp. 1433-1436
-
-
Roylance, R.1
Gorman, P.2
Harris, W.3
Liebmann, R.4
Barnes, D.5
Hanby, A.6
-
35
-
-
0035860140
-
Tumour markers in breast carcinoma correlate with grade rather than with invasiveness
-
Warnberg F., Nordgren H., Bergkvist L., and Holmberg L. Tumour markers in breast carcinoma correlate with grade rather than with invasiveness. Br. J. Cancer 85 (2001) 869-874
-
(2001)
Br. J. Cancer
, vol.85
, pp. 869-874
-
-
Warnberg, F.1
Nordgren, H.2
Bergkvist, L.3
Holmberg, L.4
|