The 5-hydroxytryptamine2A receptor antagonist R-(+)-α-(2,3- dimethoxyphenyl)-1-2-(4-fluorophenyl)ethyl-4-piperidinemethanol (M100907) attenuates impulsivity after both drug-induced disruption (dizocilpine) and enhancement (antidepressant drugs) of differential-reinforcement-of-low-rate 72-s behavior in the rat

Journal of Pharmacology and Experimental Therapeutics

Volumn 327, Issue 3, 2008, Pages 891-897

  Ardayfio, Paul A ^a   Benvenga, Mark J ^a   Chaney, Stephen F ^a   Love, Patrick L ^a   Catlow, John ^a   Swanson, Steven P ^a   Marek, Gerard J ^a,b  

^a ELI LILLY AND COMPANY   (United States)

^b ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; DESIPRAMINE; DIZOCILPINE; FLUOXETINE; MONOAMINE OXIDASE INHIBITOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; SEROTONIN 2A ANTAGONIST; TRANYLCYPROMINE; TRICYCLIC ANTIDEPRESSANT AGENT; VOLINANSERIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG RECEPTOR BINDING; HISTOPATHOLOGY; IMPULSIVENESS; LOW DRUG DOSE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; REINFORCEMENT; SUICIDE; THALAMOCORTICAL TRACT;

ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; DIZOCILPINE MALEATE; FLUOROBENZENES; PIPERIDINES; RATS; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, N-METHYL-D-ASPARTATE; REINFORCEMENT (PSYCHOLOGY); SEROTONIN ANTAGONISTS;

EID: 57349160498     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.143370     Document Type: Article

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