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Volumn 28, Issue 24, 2008, Pages 7354-7367

Altered TNSALP expression and phosphate regulation contribute to reduced mineralization in mice lacking androgen receptor

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; ANDROGEN RECEPTOR; GLYCOPROTEIN; PHOSPHATE; SMALL INTEGRIN BINDING LIGAND N LINKED GLYCOPROTEIN; TISSUE NONSPECIFIC ALKALINE PHOSPHATASE; UNCLASSIFIED DRUG;

EID: 57349156592     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00582-08     Document Type: Article
Times cited : (18)

References (60)
  • 3
    • 0142149155 scopus 로고    scopus 로고
    • Osteopontin regulation by inorganic phosphate is ERK1/2-, protein kinase C-, and proteasome-dependent
    • Beck, G. R., Jr., and N. Knecht. 2003. Osteopontin regulation by inorganic phosphate is ERK1/2-, protein kinase C-, and proteasome-dependent. J. Biol. Chem. 278:41921-41929.
    • (2003) J. Biol. Chem , vol.278 , pp. 41921-41929
    • Beck Jr., G.R.1    Knecht, N.2
  • 4
    • 12944328005 scopus 로고    scopus 로고
    • Phosphate is a specific signal for induction of osteopontin gene expression
    • Beck, G. R., Jr., B. Zerler, and E. Moran. 2000. Phosphate is a specific signal for induction of osteopontin gene expression. Proc. Natl. Acad. Sci. USA 97:8352-8357.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 8352-8357
    • Beck Jr., G.R.1    Zerler, B.2    Moran, E.3
  • 6
    • 0029984140 scopus 로고    scopus 로고
    • Expression patterns of bone-related proteins during osteoblastic differentiation in MC3T3-E1 cells
    • Choi, J. Y., B. H. Lee, K. B. Song, R. W. Park, I. S. Kim, K. Y. Sohn, J. S. Jo, and H. M. Ryoo. 1996. Expression patterns of bone-related proteins during osteoblastic differentiation in MC3T3-E1 cells. J. Cell Biochem. 61:609-618.
    • (1996) J. Cell Biochem , vol.61 , pp. 609-618
    • Choi, J.Y.1    Lee, B.H.2    Song, K.B.3    Park, R.W.4    Kim, I.S.5    Sohn, K.Y.6    Jo, J.S.7    Ryoo, H.M.8
  • 7
    • 0030878043 scopus 로고    scopus 로고
    • Absence of androgen-mediated transcriptional effects in osteoblastic cells despite presence of androgen receptors
    • Czerwiec, F. S., J. J. Liaw, S. B. Liu, C. Perez-Stable, R. Grumbles, G. A. Howard, B. A. Roos, and K. L. Burnstein. 1997. Absence of androgen-mediated transcriptional effects in osteoblastic cells despite presence of androgen receptors. Bone 21:49-56.
    • (1997) Bone , vol.21 , pp. 49-56
    • Czerwiec, F.S.1    Liaw, J.J.2    Liu, S.B.3    Perez-Stable, C.4    Grumbles, R.5    Howard, G.A.6    Roos, B.A.7    Burnstein, K.L.8
  • 8
    • 0032432558 scopus 로고    scopus 로고
    • Osteopontin expression and function: Role in bone remodeling
    • Denhardt, D. T., and M. Noda. 1998. Osteopontin expression and function: role in bone remodeling. J. Cell Biochem. Suppl. 31:92-102.
    • (1998) J. Cell Biochem. Suppl , vol.31 , pp. 92-102
    • Denhardt, D.T.1    Noda, M.2
  • 9
    • 0014435362 scopus 로고
    • Kinetic studies on the orthophosphatase and iorganic pyrophosphatase activities of human alkaline phosphatase
    • Eaton, R. H., and D. W. Moss. 1968. Kinetic studies on the orthophosphatase and iorganic pyrophosphatase activities of human alkaline phosphatase. Enzymologia 35:168-178.
    • (1968) Enzymologia , vol.35 , pp. 168-178
    • Eaton, R.H.1    Moss, D.W.2
  • 12
    • 0026347652 scopus 로고
    • Fuller Albright. His concept of postmenopausal osteoporosis and what came of it
    • Forbes, A. P. 1991. Fuller Albright. His concept of postmenopausal osteoporosis and what came of it. Clin. Orthop. Relat. Res.:128-141.
    • (1991) Clin. Orthop. Relat. Res , pp. 128-141
    • Forbes, A.P.1
  • 13
    • 0023008195 scopus 로고
    • Osteoporosis in hypogonadal men: Role of decreased plasma 1,25-dihydroxyvitamin D, calcium malabsorption, and low bone formation
    • Francis, R. M., M. Peacock, J. E. Aaron, P. L. Selby, G. A. Taylor, J. Thompson, D. H. Marshall, and A. Horsman. 1986. Osteoporosis in hypogonadal men: role of decreased plasma 1,25-dihydroxyvitamin D, calcium malabsorption, and low bone formation. Bone 7:261-268.
    • (1986) Bone , vol.7 , pp. 261-268
    • Francis, R.M.1    Peacock, M.2    Aaron, J.E.3    Selby, P.L.4    Taylor, G.A.5    Thompson, J.6    Marshall, D.H.7    Horsman, A.8
  • 15
    • 0027175622 scopus 로고
    • Flutamide-mediated androgen blockade evokes osteopenia in the female rat
    • Goulding, A., and E. Gold. 1993. Flutamide-mediated androgen blockade evokes osteopenia in the female rat. J. Bone Miner. Res. 8:763-769.
    • (1993) J. Bone Miner. Res , vol.8 , pp. 763-769
    • Goulding, A.1    Gold, E.2
  • 16
    • 0032949669 scopus 로고    scopus 로고
    • Expression of the vitamin D receptor, of estrogen and thyroid hormone receptor alpha- and beta-isoforms, and of the androgen receptor in cultures of native mouse bone marrow and of stromal/osteoblastic cells
    • Gruber, R., K. Czerwenka, F. Wolf, G. M. Ho, M. Willheim, and M. Peterlik. 1999. Expression of the vitamin D receptor, of estrogen and thyroid hormone receptor alpha- and beta-isoforms, and of the androgen receptor in cultures of native mouse bone marrow and of stromal/osteoblastic cells. Bone 24:465-473.
    • (1999) Bone , vol.24 , pp. 465-473
    • Gruber, R.1    Czerwenka, K.2    Wolf, F.3    Ho, G.M.4    Willheim, M.5    Peterlik, M.6
  • 17
    • 0036219918 scopus 로고    scopus 로고
    • Androgen receptor (AR) coregulators: An overview
    • Heinlein, C. A., and C. Chang. 2002. Androgen receptor (AR) coregulators: an overview. Endocrinol. Rev. 23:175-200.
    • (2002) Endocrinol. Rev , vol.23 , pp. 175-200
    • Heinlein, C.A.1    Chang, C.2
  • 18
    • 0027062860 scopus 로고
    • Missense mutations of the tissuenon-specific alkaline phosphatase gene in hypophosphatasia
    • Henthorn, P. S., and M. P. Whyte. 1992. Missense mutations of the tissuenon-specific alkaline phosphatase gene in hypophosphatasia. Clin. Chem. 38:2501-2505.
    • (1992) Clin. Chem , vol.38 , pp. 2501-2505
    • Henthorn, P.S.1    Whyte, M.P.2
  • 21
    • 0027172509 scopus 로고
    • Immunohistochemical detection and northern blot analysis of estrogen receptor in osteoblastic cells
    • Ikegami, A., S. Inoue, T. Hosoi, Y. Mizuno, T. Nakamura, Y. Ouchi, and H. Orimo. 1993. Immunohistochemical detection and northern blot analysis of estrogen receptor in osteoblastic cells. J. Bone Miner. Res. 8:1103-1109.
    • (1993) J. Bone Miner. Res , vol.8 , pp. 1103-1109
    • Ikegami, A.1    Inoue, S.2    Hosoi, T.3    Mizuno, Y.4    Nakamura, T.5    Ouchi, Y.6    Orimo, H.7
  • 22
    • 10744228509 scopus 로고    scopus 로고
    • Linked deficiencies in extracellular PPi and osteopontin mediate pathologic calcification associated with defective PC-1 and ANK expression
    • Johnson, K., J. Goding, D. Van Etten, A. Sali, S. I. Hu, D. Farley, H. Krug, L. Hessle, J. L. Millan, and R. Terkeltaub. 2003. Linked deficiencies in extracellular PPi and osteopontin mediate pathologic calcification associated with defective PC-1 and ANK expression. J. Bone Miner. Res. 18:994-1004.
    • (2003) J. Bone Miner. Res , vol.18 , pp. 994-1004
    • Johnson, K.1    Goding, J.2    Van Etten, D.3    Sali, A.4    Hu, S.I.5    Farley, D.6    Krug, H.7    Hessle, L.8    Millan, J.L.9    Terkeltaub, R.10
  • 23
    • 0036157487 scopus 로고    scopus 로고
    • IGF-I mediates the stimulatory effect of high phosphate concentration on osteoblastic cell proliferation
    • Kanatani, M., T. Sugimoto, J. Kano, and K. Chihara. 2002. IGF-I mediates the stimulatory effect of high phosphate concentration on osteoblastic cell proliferation. J. Cell Physiol. 190:306-312.
    • (2002) J. Cell Physiol , vol.190 , pp. 306-312
    • Kanatani, M.1    Sugimoto, T.2    Kano, J.3    Chihara, K.4
  • 24
    • 16544387699 scopus 로고    scopus 로고
    • Nongenomic androgen activation of phosphatidylinositol 3-kinase/Akt signaling pathway in MC3T3-E1 osteoblasts
    • Kang, H. Y., C. L. Cho, K. L. Huang, J. C. Wang, Y. C. Hu, H. K. Lin, C. Chang, and K. E. Huang. 2004. Nongenomic androgen activation of phosphatidylinositol 3-kinase/Akt signaling pathway in MC3T3-E1 osteoblasts. J. Bone Miner. Res. 19:1181-1190.
    • (2004) J. Bone Miner. Res , vol.19 , pp. 1181-1190
    • Kang, H.Y.1    Cho, C.L.2    Huang, K.L.3    Wang, J.C.4    Hu, Y.C.5    Lin, H.K.6    Chang, C.7    Huang, K.E.8
  • 25
    • 0037113990 scopus 로고    scopus 로고
    • Differential modulation of androgen receptor-mediated transactivation by Smad3 and tumor suppressor Smad4
    • Kang, H. Y., K. E. Huang, S. Y. Chang, W. L. Ma, W. J. Lin, and C. Chang. 2002. Differential modulation of androgen receptor-mediated transactivation by Smad3 and tumor suppressor Smad4. J. Biol. Chem. 277:43749-43756.
    • (2002) J. Biol. Chem , vol.277 , pp. 43749-43756
    • Kang, H.Y.1    Huang, K.E.2    Chang, S.Y.3    Ma, W.L.4    Lin, W.J.5    Chang, C.6
  • 26
    • 0035853055 scopus 로고    scopus 로고
    • From transforming growth factor-beta signaling to androgen action: Identification of Smad3 as an androgen receptor coregulator in prostate cancer cells
    • Kang, H. Y., H. K. Lin, Y. C. Hu, S. Yeh, K. E. Huang, and C. Chang. 2001. From transforming growth factor-beta signaling to androgen action: identification of Smad3 as an androgen receptor coregulator in prostate cancer cells. Proc. Natl. Acad. Sci. USA 98:3018-3023.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 3018-3023
    • Kang, H.Y.1    Lin, H.K.2    Hu, Y.C.3    Yeh, S.4    Huang, K.E.5    Chang, C.6
  • 27
    • 0142122829 scopus 로고    scopus 로고
    • Mechanisms and clinical relevance of androgens and androgen receptor actions
    • Kang, H. Y., M. Y. Tsai, C. Chang, and K. E. Huang. 2003. Mechanisms and clinical relevance of androgens and androgen receptor actions. Chang Gung Med. J. 26:388-402.
    • (2003) Chang Gung Med. J , vol.26 , pp. 388-402
    • Kang, H.Y.1    Tsai, M.Y.2    Chang, C.3    Huang, K.E.4
  • 28
    • 0033605597 scopus 로고    scopus 로고
    • Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor
    • Kang, H. Y., S. Yeh, N. Fujimoto, and C. Chang. 1999. Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor. J. Biol. Chem. 274:8570-8576.
    • (1999) J. Biol. Chem , vol.274 , pp. 8570-8576
    • Kang, H.Y.1    Yeh, S.2    Fujimoto, N.3    Chang, C.4
  • 29
    • 8344272750 scopus 로고    scopus 로고
    • Coregulator recruitment and histone modifications in transcriptional regulation by the androgen receptor
    • Kang, Z., O. A. Janne, and J. J. Palvimo. 2004. Coregulator recruitment and histone modifications in transcriptional regulation by the androgen receptor. Mol. Endocrinol. 18:2633-2648.
    • (2004) Mol. Endocrinol , vol.18 , pp. 2633-2648
    • Kang, Z.1    Janne, O.A.2    Palvimo, J.J.3
  • 35
    • 18244392685 scopus 로고    scopus 로고
    • Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to bone
    • Murshed, M., D. Harmey, J. L. Millan, M. D. McKee, and G. Karsenty. 2005. Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to bone. Genes Dev. 19:1093-1104.
    • (2005) Genes Dev , vol.19 , pp. 1093-1104
    • Murshed, M.1    Harmey, D.2    Millan, J.L.3    McKee, M.D.4    Karsenty, G.5
  • 39
    • 18144423170 scopus 로고    scopus 로고
    • Regulation of the human tissue-nonspecific alkaline phosphatase gene expression by all-trans-retinoic acid in SaOS-2 osteosarcoma cell line
    • Orimo, H., and T. Shimada. 2005. Regulation of the human tissue-nonspecific alkaline phosphatase gene expression by all-trans-retinoic acid in SaOS-2 osteosarcoma cell line. Bone 36:866-876.
    • (2005) Bone , vol.36 , pp. 866-876
    • Orimo, H.1    Shimada, T.2
  • 40
    • 0037097976 scopus 로고    scopus 로고
    • FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease
    • Ornitz, D. M., and P. J. Marie. 2002. FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease. Genes Dev. 16:1446-1465.
    • (2002) Genes Dev , vol.16 , pp. 1446-1465
    • Ornitz, D.M.1    Marie, P.J.2
  • 43
    • 0029670987 scopus 로고    scopus 로고
    • 17β-Oestradiol enhances the stimulatory effect of 1,25-dihydroxyvitamin D3 on alkaline phosphatase activity in human osteosarcoma SaOS-2 cells in a differentiation-dependent manner
    • Rao, L. G., J. N. Wylie, M. S. Kung Sutherland, and T. M. Murray. 1996. 17β-Oestradiol enhances the stimulatory effect of 1,25-dihydroxyvitamin D3 on alkaline phosphatase activity in human osteosarcoma SaOS-2 cells in a differentiation-dependent manner. J. Endocrinol. 148:181-187.
    • (1996) J. Endocrinol , vol.148 , pp. 181-187
    • Rao, L.G.1    Wylie, J.N.2    Kung Sutherland, M.S.3    Murray, T.M.4
  • 44
    • 84984555110 scopus 로고
    • The metabolic effects of steroid hormones in osteoporosis
    • Reifenstein, E. C., and F. Albright. 1947. The metabolic effects of steroid hormones in osteoporosis. J. Clin. Investig. 26:24-56.
    • (1947) J. Clin. Investig , vol.26 , pp. 24-56
    • Reifenstein, E.C.1    Albright, F.2
  • 45
    • 33644607426 scopus 로고    scopus 로고
    • Osteoporosis and male age-related hypogonadism: Role of sex steroids on bone (patho)physiology
    • Rochira, V., A. Balestrieri, B. Madeo, L. Zirilli, A. R. Granata, and C. Carani. 2006. Osteoporosis and male age-related hypogonadism: role of sex steroids on bone (patho)physiology. Eur. J. Endocrinol. 154:175-185.
    • (2006) Eur. J. Endocrinol , vol.154 , pp. 175-185
    • Rochira, V.1    Balestrieri, A.2    Madeo, B.3    Zirilli, L.4    Granata, A.R.5    Carani, C.6
  • 46
    • 2342563972 scopus 로고    scopus 로고
    • Study of androgen action in bone by analysis of androgen-receptor deficient mice
    • Sato, T., H. Kawano, and S. Kato. 2002. Study of androgen action in bone by analysis of androgen-receptor deficient mice. J. Bone Miner. Metab. 20:326-330.
    • (2002) J. Bone Miner. Metab , vol.20 , pp. 326-330
    • Sato, T.1    Kawano, H.2    Kato, S.3
  • 48
    • 0028030103 scopus 로고
    • Androgens directly stimulate mineralization and increase androgen receptors in human osteoblastlike osteosarcoma cells
    • Takeuchi, M., H. Kakushi, and M. Tohkin. 1994. Androgens directly stimulate mineralization and increase androgen receptors in human osteoblastlike osteosarcoma cells. Biochem. Biophys. Res. Commun. 204:905-911.
    • (1994) Biochem. Biophys. Res. Commun , vol.204 , pp. 905-911
    • Takeuchi, M.1    Kakushi, H.2    Tohkin, M.3
  • 49
    • 0034284970 scopus 로고    scopus 로고
    • Bone resorption by osteoclasts
    • Teitelbaum, S. L. 2000. Bone resorption by osteoclasts. Science 289:1504-1508.
    • (2000) Science , vol.289 , pp. 1504-1508
    • Teitelbaum, S.L.1
  • 53
    • 33645329097 scopus 로고    scopus 로고
    • Relative impact of androgen and estrogen receptor activation in the effects of androgens on trabecular and cortical bone in growing male mice: A study in the androgen receptor knockout mouse model
    • Venken, K., K. De Gendt, S. Boonen, J. Ophoff, R. Bouillon, J. V. Swinnen, G. Verhoeven, and D. Vanderschueren. 2006. Relative impact of androgen and estrogen receptor activation in the effects of androgens on trabecular and cortical bone in growing male mice: a study in the androgen receptor knockout mouse model. J. Bone Miner. Res. 21:576-585.
    • (2006) J. Bone Miner. Res , vol.21 , pp. 576-585
    • Venken, K.1    De Gendt, K.2    Boonen, S.3    Ophoff, J.4    Bouillon, R.5    Swinnen, J.V.6    Verhoeven, G.7    Vanderschueren, D.8
  • 54
    • 0029115393 scopus 로고
    • Mice lacking tissue nonspecific alkaline phosphatase die from seizures due to defective metabolism of vitamin B6
    • Waymire, K. G., J. D. Mahuren, J. M. Jaje, T. R. Guilarte, S. P. Coburn, and G. R. MacGregor. 1995. Mice lacking tissue nonspecific alkaline phosphatase die from seizures due to defective metabolism of vitamin B6. Nat. Genet. 11:45-51.
    • (1995) Nat. Genet , vol.11 , pp. 45-51
    • Waymire, K.G.1    Mahuren, J.D.2    Jaje, J.M.3    Guilarte, T.R.4    Coburn, S.P.5    MacGregor, G.R.6
  • 55
    • 0027930471 scopus 로고
    • Hypophosphatasia and the role of alkaline phosphatase in skeletal mineralization
    • Whyte, M. P. 1994. Hypophosphatasia and the role of alkaline phosphatase in skeletal mineralization. Endocrinol. Rev. 15:439-461.
    • (1994) Endocrinol. Rev , vol.15 , pp. 439-461
    • Whyte, M.P.1
  • 56
    • 22244471028 scopus 로고    scopus 로고
    • Osteopontin and related SIBLING glycoprotein genes are expressed by Sertoli cells during mouse testis development
    • Wilson, M. J., L. Liaw, and P. Koopman. 2005. Osteopontin and related SIBLING glycoprotein genes are expressed by Sertoli cells during mouse testis development. Dev. Dyn. 233:1488-1495.
    • (2005) Dev. Dyn , vol.233 , pp. 1488-1495
    • Wilson, M.J.1    Liaw, L.2    Koopman, P.3
  • 57
    • 0033305183 scopus 로고    scopus 로고
    • Homologous androgen receptor up-regulation in osteoblastic cells may be associated with enhanced functional androgen responsiveness
    • Wiren, K., E. Keenan, X. Zhang, B. Ramsey, and E. Orwoll. 1999. Homologous androgen receptor up-regulation in osteoblastic cells may be associated with enhanced functional androgen responsiveness. Endocrinology 140: 3114-3124.
    • (1999) Endocrinology , vol.140 , pp. 3114-3124
    • Wiren, K.1    Keenan, E.2    Zhang, X.3    Ramsey, B.4    Orwoll, E.5
  • 58
    • 0030954484 scopus 로고    scopus 로고
    • Transcriptional up-regulation of the human androgen receptor by androgen in bone cells
    • Wiren, K. M., X. Zhang, C. Chang, E. Keenan, and E. S. Orwoll. 1997. Transcriptional up-regulation of the human androgen receptor by androgen in bone cells. Endocrinology 138:2291-2300.
    • (1997) Endocrinology , vol.138 , pp. 2291-2300
    • Wiren, K.M.1    Zhang, X.2    Chang, C.3    Keenan, E.4    Orwoll, E.S.5
  • 59
    • 3042541735 scopus 로고    scopus 로고
    • Targeted overexpression of androgen receptor in osteoblasts: Unexpected complex bone phenotype in growing animals
    • Wiren, K. M., X. W. Zhang, A. R. Toombs, V. Kasparcova, M. A. Gentile, S. Harada, and K. J. Jepsen. 2004. Targeted overexpression of androgen receptor in osteoblasts: unexpected complex bone phenotype in growing animals. Endocrinology 145:3507-3522.
    • (2004) Endocrinology , vol.145 , pp. 3507-3522
    • Wiren, K.M.1    Zhang, X.W.2    Toombs, A.R.3    Kasparcova, V.4    Gentile, M.A.5    Harada, S.6    Jepsen, K.J.7


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