Selective vulnerability of neurons in primary cultures and in neurodegenerative diseases

Reviews in the Neurosciences

Volumn 19, Issue 4-5, 2008, Pages 317-326

  Chen, Jianmin ^a   Herrup, Karl ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; Days in vitro; Gender; Inbred strains; Neuronal birth dates; Primary neuron; Selective vulnerability

Indexed keywords

AMYLOID BETA PROTEIN;

ALZHEIMER DISEASE; BRAIN CORTEX; BRAIN NERVE CELL; BRAIN REGION; CELL ASSAY; CELL COMPOSITION; CELL DIVISION; CELL TYPE; DEGENERATIVE DISEASE; DEVELOPMENTAL STAGE; HUMAN; IN VITRO STUDY; MOUSE STRAIN; NEOCORTEX; NERVE CELL CULTURE; NERVE CELL DIFFERENTIATION; NERVE CELL GROWTH; NONHUMAN; PRIORITY JOURNAL; REVIEW; SEX DIFFERENCE;

EID: 57349113719     PISSN: 03341763     EISSN: None     Source Type: Journal    
DOI: 10.1515/REVNEURO.2008.19.4-5.317     Document Type: Review

References (73)

1. Aboitiz F, Morales D, Montiei J. The inverted neurogenetic gradient of the mammalian isocortex: development and evolution. Brain Res Brain Res Rev 2001;38:129-139.
2. Airey DC, Robbins AI, Enzinger KM, Wu F, Collins CE. Variation in the cortical area map of C57BL/6J and DBA/2J inbred mice predicts strain identity. BMC Neurosci 2005;6:18.
3. Angevine JB Jr, Sidman RL. Autoradiographic study of cell migration during histogenesis of cerebral cortex in the mouse. Nature 1961;192:766-768.
4. Banker GA, Cowan WM. Rat hippocampal neurons in dispersed cell culture. Brain Res 1977;126:397-342.
5. Bayer TA, Schafer S, Simons A, et al. Dietary Cu stabilizes brain superoxide dismutase I activity and reduces amyloid Aβ production in APP23 transgenic mice. Proc Natl Acad Sci USA 2003;100:14187-14192.
6. Berry M, Rogers AW. The migration of neuroblasts in the developing cerebral cortex. J Anat 1965;99:691-709.
7. Beyer C, Pilgrim C, Reisert I. Dopamine content and metabolism in mesencephalic and diencephalic cell cultures: sex differences and effects of sex steroids. J Neurosci 1991;11:1325-1333.
8. Braak H, Alafuzoff I, Arzberger T, Kretzschmar H, Del Tredici K. Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry. Acta Neuropathol (Berl) 2006;112:389-404.
9. Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (Berl) 1991;82:239-259.
10. Brewer GJ, Torricelli JR. Isolation and culture of adult neurons and neurospheres. Nat Protoc 2007;2:1490-1498.
11. Callahan MJ, Lipinski WJ, Bian F, Durham RA, Pack A, Walker LC. Augmented senile plaque load in aged female beta-amyloid precursor protein-transgenic mice. Am J Patho 12001;158:1173-1177.
12. Camacho IE, Serneels L, Spittaels K, Merchiers P, Dominguez D, De Strooper B. Peroxisome-proliferatoractivated receptor gamma induces a clearance mechanism for the amyloid-beta peptide. J Neurosci 2004;24:10908-10917.
13. Carruth LL, Reisert I, Arnold AP. Sex chromosome genes directly affect brain sexual differentiation. Nat Neurosci 2002;5:933-934.
14. Cohen D, Eisdorfer C, Gorelick P, et al. Sex differences in the psychiatric manifestations of Alzheimer's disease. J Am Geriatr Soc 1993;41:229-232.
15. Dewing P, Shi T, Horvath S, Vilain E. Sexually dimorphic gene expression in mouse brain precedes gonadal differentiation. Brain Res Mol Brain Res 2003;118:82-90.
16. Drachman DA, Lippa CF. The etiology of Alzheimer's disease: the pathogenesis of dementia. The role of neurotoxins. Ann NY Acad Sci 1992;648:176-186.
17. Gilmore EC, Herrup K. Cortical development: receiving reelin. Curr Biol 2000;10: R162-166.
18. Guo Q, Sebastian L, Sopher BL, et al. Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation. J Neurochem 1999;72:1019-1029.
19. Gupta A, Tsai LH, Wynshaw-Boris A. Life is a journey: a genetic look at neocortical development. Nat Rev Genet 2002;3:342-355.
20. Hatten ME. Central nervous system neuronal migration. Annu Rev Neurosci 1999;22:511-539.
21. Heyer A, Hasselblatt M, von Ahsen N, Hafher H, Siren AL, Ehrenreich H. In vitro gender differences in neuronal survival on hypoxia and in 17p-estradiolmediated neuroprotection. J Cereb Blood Flow Metab 2005;25:427-430.
22. Ho PI, Ashline D, Dhitavat S, et al. Folate deprivation induces neurodegeneration: roles of oxidative stress and increased homocysteine. Neurobiol Dis 2003;14:32-42.
23. Ko J, Humbert S, Bronson RT, et al. p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment. J Neurosci 2001;21:6758-6771.
24. Kraszpulski M, Soininen H, Helisalmi S, Alafuzoff I. The load and distribution of beta-amyloid in brain tissue of patients with Alzheimer's disease. Acta Neurol Scand2001;103:88-92.
25. Lehman EJ, Kulnane LS, Gao Y, et al. Genetic background regulates beta-amyloid precursor protein processing and beta-amyloid deposition in the mouse. Hum Mol Genet 2003;12:2949-2956.
26. Lesuisse C, Martin LJ. Immature and mature cortical neurons engage different apoptotic mechanisms involving caspase-3 and the mitogen-activated protein kinase pathway. J Cereb Blood Flow Metab 2002;22:935-950.
27. Lesuisse C, Martin LJ. Long-term culture of mouse cortical neurons as a model for neuronal development, aging, and death. J Neurobiol 2002;51:9-23.
28. Lewis J, Dickson DW, Lin WL, et al. Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science 2001;293:1487-1491.
29. Li H, Pin S, Zeng Z, Wang MM, Andreasson KA, McCullough LD. Sex differences in cell death. Ann Neurol 2005;58:317-321.
30. Liu M, Hum PD, Roselli CE, Alkayed NJ. Role of P450 aromatase in sex-specific astrocytic cell death. J Cereb Blood Flow Metab 2007;27:135-141.
31. Lorenzo A, Yuan M, Zhang Z, et al. Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease. Nat Neurosci 2000;3:460-464.
32. Lyketsos CG, Steele C, Galik E, et al. Physical aggression in dementia patients and its relationship to depression. Am J Psychiatry 1999;156:66-71.
33. Mann DM, Yates PO, Marcyniuk B. Some morphometric observations on the cerebral cortex and hippocampus in presenile Alzheimer's disease, senile dementia of Alzheimer type and Down's syndrome in middle age. J Neurol Sci 1985;69:139-159.
34. Manzini MC, Joseph DJ, MacDermott AB, Mason CA. Differential effects of AMPA receptor activation on survival and neurite integrity during neuronal development. Mol Cell Neurosci 2007;35:328-338.
35. Manzini MC, Ward MS, Zhang Q, Lieberman MD, Mason CA. The stop signal revised: immature cerebellar granule neurons in the external germinal layer arrest pontine mossy fiber growth. J Neurosci 2006;26:6040-6051.
36. Masliah E, Rockenstein E, Veinbergs I, et al. Betaamyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease. Proc Natl Acad Sci USA 2001;98:12245-12250.
37. Mattson MP, Magnus T. Ageing and neuronal vulnerability. Nat Rev Neurosci 2006;7:278-294.
38. McCarthy MM. Stretching the truth. Why hippocampal neurons are so vulnerable following traumatic brain injury. Exp Neurol 2003;184:40-43.
39. McConnell SK. Strategies for the generation of neuronal diversity in the developing central nervous system. J Neurosci 1995;15:6987-6998.
40. McLaughlin P, Zhou Y, Ma T, et al. Proteomic analysis of microglial contribution to mouse strain-dependent dopaminergic neurotoxicity. Glia 2006;53:567-582.
41. Muller T, Concannon CG, Ward MW, et al. Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD). Mol Biol Cell 2007;18:201-210.
42. Muthane U, Ramsay KA, Jiang H, et al. Differences in nigral neuron number and sensitivity to l-methyl-4- phenyl-1,2,3,6-tetrahydropyridine in C57/bl and CD-I mice. Exp Neurol 1994;126:195-204.
43. Nadler JJ, Zou F, Huang H, et al. Large-scale gene expression differences across brain regions and inbred strains correlate with a behavioral phenotype. Genetics 2006;174:1229-1236.
44. Nawashiro H, Shima K, Chigasaki H. Selective vulnerability of hippocampal CA3 neurons to hypoxia after mild concussion in the rat. Neurol Res 1995;17:455-460.
45. Ott BR, Tate CA, Gordon NM, Heindel WC. Gender differences in the behavioral manifestations of Alzheimer's disease. J Am Geriatr Soc 1996;44:583-587.
46. Owen EH, Logue SF, Rasmussen DL, Wehner JM. Assessment of learning by the Morris water task and fear conditioning in inbred mouse strains and Ft hybrids: implications of genetic background for single gene mutations and quantitative trait loci analyses. Neuroscience 1997;80:1087-1099.
47. Pappas IS, Pamavelas JG. Neurotrophins and basic fibroblast growth factor induce the differentiation of calbindin-containing neurons in the cerebral cortex. ExpNeurol 1997;144:302-314.
48. Patel JR, Brewer GJ. Age-related changes in neuronal glucose uptake in response to glutamate and betaamyloid. J Neurosci Res 2003;72:527-536.
49. Pavlidis P, Noble WS. Analysis of strain and regional variation in gene expression in mouse brain. Genome Biol 2001;2: RESEARCH0042.
50. Paylor R, Tracy R, Wehner J, Rudy JW. DBA/2 and C57BL/6 mice differ in contextual fear but not auditory fear conditioning. Behav Neurosci 1994;108:810-817.
51. Prapong T, Buss J, Hsu WH, Heine P, West Greenlee H, Uemura E. Amyloid beta-peptide decreases neuronal glucose uptake despite causing increase in GLUT3 mRNA transcription and GLUT3 translocation to the plasma membrane. Exp Neurol 2002;174:253-258.
52. Raetzman LT, Siegel RE. Immature granule neurons from cerebella of different ages exhibit distinct developmental potentials. J Neurobiol 1999;38:559-570.
53. Ripich DN, Petrill SA, Whitehouse PJ, Ziol EW. Gender differences in language of AD patients: a longitudinal study. Neurology 1995;45:299-302.
54. Romito-DiGiacomo RR, Menegay H, Cicero SA, Herrup K. Effects of Alzheimer's disease on different cortical layers: the role of intrinsic differences in Ap susceptibility. J Neurosci 2007;27:8496-8504.
55. Ryman D, Lamb BT. Genetic and environmental modifiers of Alzheimer's disease phenotypes in the mouse. Curr Alzheimer Res 2006;3:465-473.
56. Schafer S, Wirths O, Multhaup G, Bayer TA. Gender dependent APP processing in a transgenic mouse model of Alzheimer's disease. J Neural Transm 2007;114:387-394.
57. Shuttleworth CW, Connor JA. Strain-dependent differences in calcium signaling predict excitotoxicity in murine hippocampal neurons. J Neurosci 2001;21:4225-4236.
58. Sibug R, Kuppers E, Beyer C, Maxson SC, Pilgrim C, Reisert I. Genotype-dependent sex differentiation of dopaminergic neurons in primary cultures of embryonic mouse brain. Brain Res Dev Brain Res 1996;93:136-142.
59. Smeyne M, Goloubeva O, Smeyne RJ. Strain-dependent susceptibility to MPTP and MPP+-induced parkinsonism is determined by glia. Glia 2001;34:73-80.
60. Steward O, Schauwecker PE, Guth L, et al. Genetic approaches to neurotrauma research: opportunities and potential pitfalls of murine models. Exp Neurol 1999;157:19-42.
61. Sturchler-Pierrat C, Staufenbiel M. Pathogenic mechanisms of Alzheimer's disease analyzed in the APP23 transgenic mouse model. Ann NY Acad Sci 2000;920:134-139.
62. Uemura E, Greenlee HW. Amyloid beta-peptide inhibits neuronal glucose uptake by preventing exocytosis. Exp Neurol 2001;170:270-276.
63. Upchurch M, Wehner JM. Inheritance of spatial learning ability in inbred mice: a classical genetic analysis. Behav Neurosci 1989;103:1251-1258.
64. Wang J, Tanila H, Puolivali J, Radish I, van Groen T. Gender differences in the amount and deposition of amyloidp in APPswe and PS1 double transgenic mice. Neurobiol Dis 2003;14:318-327.
65. Wang L, Wang R, Herrup K. E2F1 works as a cell cycle suppressor in mature neurons. J Neurosci 2007;27:12555-12564.
66. West MJ. Regionally specific loss of neurons in the aging human hippocampus. Neurobiol Aging 1993;14:287-293.
67. West MJ, Coleman PD, Flood DG, Troncoso JC. Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease. Lancet 1994;344:769-772.
68. Wetzel M, Tibbitts J, Rosenberg GA, Cunningham LA. Vulnerability of mouse cortical neurons to doxorubicininduced apoptosis is strain-dependent and is correlated with mRNAs encoding Fas, Fas-Ligand, and metalloproteinases. Apoptosis 2004;9:649-656.
69. White AR, Cappai R. Neurotoxicity from glutathione depletion is dependent on extracellular trace copper. J Neurosci Res 2003;71:889-897.
70. White AR, Zheng H, Galatis D, et al. Survival of cultured neurons from amyloid precursor protein knockout mice against Alzheimer's amyloid-beta toxicity and oxidative stress. J Neurosci 1998;18:6207-6217.
71. Windisch M, Hutter-Paier B, Schreiner E, Wronski R. P-Synuclein-derived peptides with neuroprotective activity: an alternative treatment of neurodegenerative disorders? J Mol Neurosci 2004;24:155-165.
72. Yohrling GJ, Felsenstein KM, Conway KA, Zupa- Femandez A, Brenneman DE, Arnold HM. A comparative analysis of brain and plasma AP levels in eight common non-transgenic mouse strains: validation of a specific immunoassay for total rodent Ap. Curr Alzheimer Res 2007;4:297-303.
73. Zhang L, Li PP, Feng X, Barker JL, Smith SV, Rubinow DR. Sex-related differences in neuronal cell survival and signaling in rats. Neurosci Lett 2003;337:65-68.