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Volumn 5, Issue 5, 2003, Pages 426-435

Monitoring bcr-abl by polymerase chain reaction in the treatment of chronic myeloid leukemia

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BCR ABL PROTEIN; CYTARABINE; DNA; FLUORESCENT DYE; IMATINIB; INTERFERON; MESSENGER RNA; NUCLEIC ACID; PIPERAZINE DERIVATIVE; PYRIMIDINE DERIVATIVE;

EID: 2142802114     PISSN: 15233790     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11912-003-0030-x     Document Type: Review
Times cited : (13)

References (77)
  • 1
    • 0008947293 scopus 로고    scopus 로고
    • Bone marrow transplants from unrelated donors for patients with chronic myeloid leukemia
    • Hansen JA, Gooley TA, Martin PJ, et al.: Bone marrow transplants from unrelated donors for patients with chronic myeloid leukemia. N Engl J Med 1998, 338:962-968.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 962-968
    • Hansen, J.A.1    Gooley, T.A.2    Martin, P.J.3
  • 2
    • 10744233716 scopus 로고    scopus 로고
    • Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
    • O'Brien SG, Guilhot F, Larson RA, et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med 2003, 348:994-1004.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 994-1004
    • O'Brien, S.G.1    Guilhot, F.2    Larson, R.A.3
  • 4
    • 0037085785 scopus 로고    scopus 로고
    • Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: Results of a phase 2 study
    • Talpaz M, Silver RT, Druker BJ, et al.: Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study. Blood 2002, 99:1928-1937.
    • (2002) Blood , vol.99 , pp. 1928-1937
    • Talpaz, M.1    Silver, R.T.2    Druker, B.J.3
  • 5
    • 0037093092 scopus 로고    scopus 로고
    • Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: Results of a phase II study
    • Sawyers CL, Hochhaus A, Feldman E, et al.: Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study. Blood 2002, 99:3530-3539.
    • (2002) Blood , vol.99 , pp. 3530-3539
    • Sawyers, C.L.1    Hochhaus, A.2    Feldman, E.3
  • 6
    • 0028932038 scopus 로고
    • BCR-ABL, ABL-BCR, BCR, and ABL genes are all expressed in individual granulocyte-macrophage colony-forming unit colonies derived from blood of patients with chronic myeloid leukemia
    • Diamond J, Goldman JM, Melo J V: BCR-ABL, ABL-BCR, BCR, and ABL genes are all expressed in individual granulocyte-macrophage colony-forming unit colonies derived from blood of patients with chronic myeloid leukemia. Blood 1995, 85:2171-2175.
    • (1995) Blood , vol.85 , pp. 2171-2175
    • Diamond, J.1    Goldman, J.M.2    Melo, J.V.3
  • 7
    • 0029995607 scopus 로고    scopus 로고
    • The molecular biology of chronic myeloid leukaemia
    • Melo JV: The molecular biology of chronic myeloid leukaemia. Leukemia 1996, 10:751-756.
    • (1996) Leukemia , vol.10 , pp. 751-756
    • Melo, J.V.1
  • 8
    • 0028960453 scopus 로고
    • Analysis of molecular breakpoint and m-RNA transcripts in a prospective randomized trial of interferon in chronic myeloid leukaemia: No correlation with clinical features, cytogenetic response, duration of chronic phase, or survival
    • Shepherd P, Suffolk R, Halsey J, Allan N: Analysis of molecular breakpoint and m-RNA transcripts in a prospective randomized trial of interferon in chronic myeloid leukaemia: no correlation with clinical features, cytogenetic response, duration of chronic phase, or survival. Br J Haematol 1995, 89:546-554.
    • (1995) Br. J. Haematol. , vol.89 , pp. 546-554
    • Shepherd, P.1    Suffolk, R.2    Halsey, J.3    Allan, N.4
  • 9
    • 0033565561 scopus 로고    scopus 로고
    • The biology of chronic myeloid leukemia
    • Faderl S, Talpaz M, Estrov Z, et al.: The biology of chronic myeloid leukemia. N Engl J Med 1999, 341:164-172.
    • (1999) N. Engl. J. Med. , vol.341 , pp. 164-172
    • Faderl, S.1    Talpaz, M.2    Estrov, Z.3
  • 10
    • 0023649238 scopus 로고
    • Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia
    • Hermans A, Heisterkamp N, von Linden M, et al.: Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia. Cell 1987, 51:33-40.
    • (1987) Cell , vol.51 , pp. 33-40
    • Hermans, A.1    Heisterkamp, N.2    von Linden, M.3
  • 11
    • 9544227358 scopus 로고    scopus 로고
    • A novel BCR-ABL fusion gene (e6a2) in a patient with Philadelphia chromosome-negative chronic myelogenous leukemia
    • Hochhaus A, Reiter A, Skladny H et al.: A novel BCR-ABL fusion gene (e6a2) in a patient with Philadelphia chromosome-negative chronic myelogenous leukemia. Blood 1996, 88:2236-2240.
    • (1996) Blood , vol.88 , pp. 2236-2240
    • Hochhaus, A.1    Reiter, A.2    Skladny, H.3
  • 12
    • 0025763664 scopus 로고
    • bcr-abl mRNA lacking abl exon a2 detected by polymerase chain reaction in a chronic myelogeneous leukemia patient
    • van der Plas DC, Soekarman D, van Gent AM, et al.: bcr-abl mRNA lacking abl exon a2 detected by polymerase chain reaction in a chronic myelogeneous leukemia patient. Leukemia 1991, 5:457-461.
    • (1991) Leukemia , vol.5 , pp. 457-461
    • van der Plas, D.C.1    Soekarman, D.2    van Gent, A.M.3
  • 13
    • 0034693878 scopus 로고    scopus 로고
    • Regulation of cell death by the Abl tyrosine kinase
    • Wang JY: Regulation of cell death by the Abl tyrosine kinase. Oncogene 2000, 19:5643-56450.
    • (2000) Oncogene , vol.19 , pp. 5643-56450
    • Wang, J.Y.1
  • 14
    • 0022544401 scopus 로고
    • The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene
    • Ben-Neriah Y, Daley GQ, Mes-Masson AM, et al.: The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene. Science 1986, 233:212-214.
    • (1986) Science , vol.233 , pp. 212-214
    • Ben-Neriah, Y.1    Daley, G.Q.2    Mes-Masson, A.M.3
  • 15
    • 0034670036 scopus 로고    scopus 로고
    • The molecular biology of chronic myeloid leukemia
    • Deininger MWN, Goldman JM, Melo JV: The molecular biology of chronic myeloid leukemia. Blood 2000, 96:3343-3356.
    • (2000) Blood , vol.96 , pp. 3343-3356
    • Deininger, M.W.N.1    Goldman, J.M.2    Melo, J.V.3
  • 16
    • 0017347991 scopus 로고
    • Exclusion of chromosomal mosaicism: Tables of 90%, 95% and 99% confidence limits and comments on use
    • Hook EB: Exclusion of chromosomal mosaicism: tables of 90%, 95% and 99% confidence limits and comments on use. Am J Hum Genet 1977, 29:94-97.
    • (1977) Am. J. Hum. Genet. , vol.29 , pp. 94-97
    • Hook, E.B.1
  • 17
    • 0023936288 scopus 로고
    • Cytogenetic events after bone marrow transplantation for chronic myeloid leukemia in chronic phase
    • Arthur CK, Apperley JF, Guo AP, et al.: Cytogenetic events after bone marrow transplantation for chronic myeloid leukemia in chronic phase. Blood 1988, 71:1179-1186.
    • (1988) Blood , vol.71 , pp. 1179-1186
    • Arthur, C.K.1    Apperley, J.F.2    Guo, A.P.3
  • 18
    • 0035885928 scopus 로고    scopus 로고
    • Deletions of the derivative chromosome 9 occur at the time of the Philadelphia translocation and provide a powerful and independent prognostic indicator in chronic myeloid leukemia
    • Huntly BJ, Reid AG, Bench AJ, et al.: Deletions of the derivative chromosome 9 occur at the time of the Philadelphia translocation and provide a powerful and independent prognostic indicator in chronic myeloid leukemia. Blood 2001, 98:1732-1738.
    • (2001) Blood , vol.98 , pp. 1732-1738
    • Huntly, B.J.1    Reid, A.G.2    Bench, A.J.3
  • 19
    • 12944295358 scopus 로고    scopus 로고
    • Large deletions at the t(9;22) breakpoint are common and may identify a poor-prognosis subgroup of patients with chronic myeloid leukemia
    • Sinclair PB, Nacheva EP, Leversha M, et al.: Large deletions at the t(9;22) breakpoint are common and may identify a poor-prognosis subgroup of patients with chronic myeloid leukemia. Blood 2000, 95:738-743.
    • (2000) Blood , vol.95 , pp. 738-743
    • Sinclair, P.B.1    Nacheva, E.P.2    Leversha, M.3
  • 20
    • 0029098199 scopus 로고
    • Hypermetaphase fluorescence in situ hybridization for quantitative monitoring of Philadelphia chromosome-positive cells in patients with chronic myelogenous leukemia during treatment
    • Seong DC, Kantarjian HM, Ro JY, et al.: Hypermetaphase fluorescence in situ hybridization for quantitative monitoring of Philadelphia chromosome-positive cells in patients with chronic myelogenous leukemia during treatment. Blood 1995, 86:2343-2349.
    • (1995) Blood , vol.86 , pp. 2343-2349
    • Seong, D.C.1    Kantarjian, H.M.2    Ro, J.Y.3
  • 21
    • 0028077751 scopus 로고
    • Metaphase fluorescence in situ hybridization (FISH) in the follow-up of 60 patients with haemopoietic malignancies
    • Nylund SJ, Ruutu T, Saarinen U, Knuutila S: Metaphase fluorescence in situ hybridization (FISH) in the follow-up of 60 patients with haemopoietic malignancies. Br J Haematol 1994, 88:778-783.
    • (1994) Br. J. Haematol. , vol.88 , pp. 778-783
    • Nylund, S.J.1    Ruutu, T.2    Saarinen, U.3    Knuutila, S.4
  • 22
    • 0030458650 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization in combination with morphology detects minimal residual disease in remission and heralds relapse in acute leukaemia
    • Bernell P, Arvidsson I, Jacobsson B, Hast R: Fluorescence in situ hybridization in combination with morphology detects minimal residual disease in remission and heralds relapse in acute leukaemia. Br J Haematol 1996, 95:666-672.
    • (1996) Br. J. Haematol. , vol.95 , pp. 666-672
    • Bernell, P.1    Arvidsson, I.2    Jacobsson, B.3    Hast, R.4
  • 23
    • 0032916077 scopus 로고    scopus 로고
    • Quantitation of minimal residual disease in acute myelogenous leukemia and myelodysplastic syndromes in complete remission by molecular cytogenetics of progenitor cells
    • Engel H, Drach J, Keyhani A, Jiang S, et al.: Quantitation of minimal residual disease in acute myelogenous leukemia and myelodysplastic syndromes in complete remission by molecular cytogenetics of progenitor cells. Leukemia 1999, 13:568-577.
    • (1999) Leukemia , vol.13 , pp. 568-577
    • Engel, H.1    Drach, J.2    Keyhani, A.3    Jiang, S.4
  • 24
    • 0032532736 scopus 로고    scopus 로고
    • Fluorescent in situ hybridization on flow-sorted cells as a tool for evaluating minimal residual disease or chimerism after allogenic bone marrow transplantation
    • Cotteret S, Belloc F, Boiron JM, et al.: Fluorescent in situ hybridization on flow-sorted cells as a tool for evaluating minimal residual disease or chimerism after allogenic bone marrow transplantation. Cytometry 1998, 34:216-222.
    • (1998) Cytometry , vol.34 , pp. 216-222
    • Cotteret, S.1    Belloc, F.2    Boiron, J.M.3
  • 25
    • 0036919280 scopus 로고    scopus 로고
    • Targeting multiple genetic aberrations in isolated tumor cells by spectral fluorescence in situ hybridization
    • Slovak ML, Zhang F, Tcheurekdjian L, et al.: Targeting multiple genetic aberrations in isolated tumor cells by spectral fluorescence in situ hybridization. Cancer Detect Prev 2002, 26:171-179.
    • (2002) Cancer Detect. Prev. , vol.26 , pp. 171-179
    • Slovak, M.L.1    Zhang, F.2    Tcheurekdjian, L.3
  • 27
    • 0028946866 scopus 로고
    • Polymerase chain reaction detection of BCR/ABL fusion transcript after allogeneic marrow transplantation for chronic myeloid leukemia: Results and implications in 346 patients
    • Radich JP, Gehly G, Gooley T, et al.: Polymerase chain reaction detection of BCR/ABL fusion transcript after allogeneic marrow transplantation for chronic myeloid leukemia: results and implications in 346 patients. Blood 1995, 85:2632-2638.
    • (1995) Blood , vol.85 , pp. 2632-2638
    • Radich, J.P.1    Gehly, G.2    Gooley, T.3
  • 28
    • 0035885940 scopus 로고    scopus 로고
    • The significance of bcr-abl molecular detection in chronic myeloid leukemia patients 'late', 18 months or more after transplantation
    • Radich JP, Gooloey T, Bryant E, et al.: The significance of bcr-abl molecular detection in chronic myeloid leukemia patients 'late', 18 months or more after transplantation. Blood 2001, 98:1701-1707.
    • (2001) Blood , vol.98 , pp. 1701-1707
    • Radich, J.P.1    Gooloey, T.2    Bryant, E.3
  • 29
    • 0344614012 scopus 로고    scopus 로고
    • Accurate and rapid analysis of residual disease in patients with CML using specific fluorescent hybridization probes for real time quantitative RT-PCR
    • Emig M, Saussele S, Wittor H, et al.: Accurate and rapid analysis of residual disease in patients with CML using specific fluorescent hybridization probes for real time quantitative RT-PCR. Leukemia 1999, 13:1825-1832.
    • (1999) Leukemia , vol.13 , pp. 1825-1832
    • Emig, M.1    Saussele, S.2    Wittor, H.3
  • 30
    • 0026504676 scopus 로고
    • Prognostic significance of Philadelphia chromosome-positive cells detected by the polymerase chain reaction after allogeneic bone marrow transplant for chronic myelogenous leukemia
    • Roth MS, Antin JH, Ash R, et al.: Prognostic significance of Philadelphia chromosome-positive cells detected by the polymerase chain reaction after allogeneic bone marrow transplant for chronic myelogenous leukemia. Blood 1992, 79:276-282.
    • (1992) Blood , vol.79 , pp. 276-282
    • Roth, M.S.1    Antin, J.H.2    Ash, R.3
  • 31
    • 0027465939 scopus 로고
    • Long persistent bcr-abl positive transcript detected by polymerase chain reaction after marrow transplant for chronic myelogenous leukemia without clinical relapse: A study of 64 patients
    • Miyamura K, Tahara T, Tanimoto M, et al.: Long persistent bcr-abl positive transcript detected by polymerase chain reaction after marrow transplant for chronic myelogenous leukemia without clinical relapse: a study of 64 patients. Blood 1993, 81:1089-1093.
    • (1993) Blood , vol.81 , pp. 1089-1093
    • Miyamura, K.1    Tahara, T.2    Tanimoto, M.3
  • 32
    • 0031772383 scopus 로고    scopus 로고
    • Minimal residual disease in chronic myeloid leukaemia
    • Cross NC: Minimal residual disease in chronic myeloid leukaemia. Hematol Cell Ther 1998, 40:224-228.
    • (1998) Hematol. Cell Ther. , vol.40 , pp. 224-228
    • Cross, N.C.1
  • 33
    • 0030026450 scopus 로고    scopus 로고
    • Minimal residual disease after allogeneic bone marrow transplantation for chronic myeloid leukaemia: A metaphase-FISH study
    • el-Rifai W, Ruutu T, Vettenranta K, et al.: Minimal residual disease after allogeneic bone marrow transplantation for chronic myeloid leukaemia: a metaphase-FISH study. Br J Haematol 1996, 92:365-369.
    • (1996) Br. J. Haematol. , vol.92 , pp. 365-369
    • el-Rifai, W.1    Ruutu, T.2    Vettenranta, K.3
  • 34
    • 0026059997 scopus 로고
    • Detection of residual leukemia after bone marrow transplant for chronic myeloid leukemia: Role of polymerase chain reaction in predicting relapse
    • Hughes TP, Morgan GJ, Martiat P, Goldman JM: Detection of residual leukemia after bone marrow transplant for chronic myeloid leukemia: role of polymerase chain reaction in predicting relapse. Blood 1991, 77:874-878.
    • (1991) Blood , vol.77 , pp. 874-878
    • Hughes, T.P.1    Morgan, G.J.2    Martiat, P.3    Goldman, J.M.4
  • 35
    • 0035672953 scopus 로고    scopus 로고
    • Molecular studies in patients with chronic myeloid leukaemia in remission 5 years after allogeneic stem cell transplant define the risk of subsequent relapse
    • Mughal TI, Yong A, Szydlo RM, et al.: Molecular studies in patients with chronic myeloid leukaemia in remission 5 years after allogeneic stem cell transplant define the risk of subsequent relapse. Br J Haematol 2001, 115:569-574.
    • (2001) Br. J. Haematol. , vol.115 , pp. 569-574
    • Mughal, T.I.1    Yong, A.2    Szydlo, R.M.3
  • 36
    • 0029060475 scopus 로고
    • Distinct patterns of minimal residual disease associated with graft-versus-host disease after allogeneic bone marrow transplantation for chronic myelogenous leukemia
    • Pichert G, Roy D-C, Gonin R, et al.: Distinct patterns of minimal residual disease associated with graft-versus-host disease after allogeneic bone marrow transplantation for chronic myelogenous leukemia. J Clin Oncol 1995, 13:1704-1713.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 1704-1713
    • Pichert, G.1    Roy, D.-C.2    Gonin, R.3
  • 37
    • 0029563299 scopus 로고    scopus 로고
    • Value of PCR analysis for long term survivors after allogeneic bone marrow transplant for chronic myelogenous leukemia: A comparative study
    • Costello RT, Kirk J, Gabert J: Value of PCR analysis for long term survivors after allogeneic bone marrow transplant for chronic myelogenous leukemia: a comparative study. Leuk Lymphoma 1996, 20:239-242.
    • (1996) Leuk. Lymphoma , vol.20 , pp. 239-242
    • Costello, R.T.1    Kirk, J.2    Gabert, J.3
  • 38
    • 0027945482 scopus 로고
    • Detection of residual leukaemia more than 10 years after allogeneic bone marrow transplantation for chronic myelogenous leukemia
    • van Rhee F, Cross NCP, Reid CDL, et al.: Detection of residual leukaemia more than 10 years after allogeneic bone marrow transplantation for chronic myelogenous leukemia. Bone Marrow Transplant 1994, 14:609-612.
    • (1994) Bone Marrow Transplant , vol.14 , pp. 609-612
    • van Rhee, F.1    Cross, N.C.P.2    Reid, C.D.L.3
  • 39
    • 0035383762 scopus 로고    scopus 로고
    • Hematopoietic cell transplantation in older patients with hematologic malignancies: Replacing high-dose cytotoxic therapy with graft-versus-tumor effects
    • McSweeney PA, Niederwieser D, Shizuru JA, et al.: Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus-tumor effects. Blood 2001, 97:3390-3400.
    • (2001) Blood , vol.97 , pp. 3390-3400
    • McSweeney, P.A.1    Niederwieser, D.2    Shizuru, J.A.3
  • 40
    • 0029981482 scopus 로고    scopus 로고
    • Polymerase chain reaction is highly predictive of relapse in patients following T cell-depleted allogeneic bone marrow transplantation for chronic myeloid leukemia
    • Mackinnon S, Barnett L, Heller G: Polymerase chain reaction is highly predictive of relapse in patients following T cell-depleted allogeneic bone marrow transplantation for chronic myeloid leukemia. Bone Marrow Transplant 1996, 17:643-647.
    • (1996) Bone Marrow Transplant , vol.17 , pp. 643-647
    • Mackinnon, S.1    Barnett, L.2    Heller, G.3
  • 41
    • 0029925863 scopus 로고    scopus 로고
    • Kinetics of increasing BCR-ABL transcript numbers in chronic myeloid leukemia patients who relapse after bone marrow transplantation
    • Lin F, van Rhee F, Goldman JM, Cross NCP: Kinetics of increasing BCR-ABL transcript numbers in chronic myeloid leukemia patients who relapse after bone marrow transplantation. Blood 1996, 87:4473-4478.
    • (1996) Blood , vol.87 , pp. 4473-4478
    • Lin, F.1    van Rhee, F.2    Goldman, J.M.3    Cross, N.C.P.4
  • 42
    • 0031840623 scopus 로고    scopus 로고
    • Quantitation of minimal residual disease in Philadelphia chromosome positive chronic myeloid leukemia patients using real-time quantitative RT-PCR
    • Mensink E, van de Locht A, Schattenberg A, et al.: Quantitation of minimal residual disease in Philadelphia chromosome positive chronic myeloid leukemia patients using real-time quantitative RT-PCR. Br J Haematol 1998, 102:768-774.
    • (1998) Br. J. Haematol. , vol.102 , pp. 768-774
    • Mensink, E.1    van de Locht, A.2    Schattenberg, A.3
  • 43
    • 0033023907 scopus 로고    scopus 로고
    • Detection of BCR-ABL transcripts in chronic myeloid leukemia (CML) using an in situ RT-PCR assay
    • Preudhomme C, Chams-Eddine L, Roumier C, et al.: Detection of BCR-ABL transcripts in chronic myeloid leukemia (CML) using an in situ RT-PCR assay. Leukemia 1999, 13:818-823.
    • (1999) Leukemia , vol.13 , pp. 818-823
    • Preudhomme, C.1    Chams-Eddine, L.2    Roumier, C.3
  • 44
    • 0035869422 scopus 로고    scopus 로고
    • Early detection of BCR-ABL transcripts by quantitative reverse transcriptase-polymerase chain reaction predicts outcome after allogeneic stem cell transplantation for chronic myeloid leukemia
    • Olavarria E, Kanfer E, Szydlo R, et al.: Early detection of BCR-ABL transcripts by quantitative reverse transcriptase-polymerase chain reaction predicts outcome after allogeneic stem cell transplantation for chronic myeloid leukemia. Blood 2001, 97:1560-1565.
    • (2001) Blood , vol.97 , pp. 1560-1565
    • Olavarria, E.1    Kanfer, E.2    Szydlo, R.3
  • 45
    • 0032748325 scopus 로고    scopus 로고
    • Monitoring chronic myeloid leukaemia therapy by real-time quantitative PCR in blood is a reliable alternative to bone marrow cytogenetics
    • Branford S, Hughes TP, Rudzki Z: Monitoring chronic myeloid leukaemia therapy by real-time quantitative PCR in blood is a reliable alternative to bone marrow cytogenetics. Br J Haematol 1999, 107:587-599.
    • (1999) Br. J. Haematol. , vol.107 , pp. 587-599
    • Branford, S.1    Hughes, T.P.2    Rudzki, Z.3
  • 46
    • 0025012831 scopus 로고
    • Molecular relapse in chronic myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction
    • Sawyers CL, Timson L, Kawasaki ES, et al.: Molecular relapse in chronic myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction. Proc Natl Acad Sci U S A 1990, 87:563-567.
    • (1990) Proc. Natl. Acad. Sci. U S A , vol.87 , pp. 563-567
    • Sawyers, C.L.1    Timson, L.2    Kawasaki, E.S.3
  • 47
    • 0034660923 scopus 로고    scopus 로고
    • No evidence for persistence of BCR-ABL-positive cells in patients in molecular remission after conventional allogenic transplantation for chronic myeloid leukemia
    • Deininger M, Lehmann T, Krahl R, et al.: No evidence for persistence of BCR-ABL-positive cells in patients in molecular remission after conventional allogenic transplantation for chronic myeloid leukemia. Blood 2000, 96:779-780.
    • (2000) Blood , vol.96 , pp. 779-780
    • Deininger, M.1    Lehmann, T.2    Krahl, R.3
  • 48
    • 0034661564 scopus 로고    scopus 로고
    • Absence of host-derived cells in the blood of patients in remission after allografting for chronic myeloid leukemia
    • Chase A, Parker S, Kaeda J, et al.: Absence of host-derived cells in the blood of patients in remission after allografting for chronic myeloid leukemia. Blood 2000, 96:777-778.
    • (2000) Blood , vol.96 , pp. 777-778
    • Chase, A.1    Parker, S.2    Kaeda, J.3
  • 49
    • 0034650993 scopus 로고    scopus 로고
    • Persistence of BCR-ABL genomic rearrangement in chronic myeloid leukemia patients in complete and sustained cytogenetic remission after interferon-alpha therapy or allogeneic bone marrow transplantation
    • Chomel JC, Brizard F, Veinstein A, et al.: Persistence of BCR-ABL genomic rearrangement in chronic myeloid leukemia patients in complete and sustained cytogenetic remission after interferon-alpha therapy or allogeneic bone marrow transplantation. Blood 2000, 95:404-409.
    • (2000) Blood , vol.95 , pp. 404-409
    • Chomel, J.C.1    Brizard, F.2    Veinstein, A.3
  • 50
    • 0029078021 scopus 로고
    • Characterization of genomic BCR-ABL breakpoints in chronic myeloid leukaemia by PCR
    • Zhang JG, Goldman JM, Cross NC: Characterization of genomic BCR-ABL breakpoints in chronic myeloid leukaemia by PCR. Br J Haematol 1995, 90:138-146.
    • (1995) Br. J. Haematol. , vol.90 , pp. 138-146
    • Zhang, J.G.1    Goldman, J.M.2    Cross, N.C.3
  • 51
    • 9344261193 scopus 로고    scopus 로고
    • Comparison of genomic DNA and cDNA for detection of residual disease after treatment of chronic myeloid leukemia with allogeneic bone marrow transplantation
    • Zhang JG, Lin F, Chase A, et al.: Comparison of genomic DNA and cDNA for detection of residual disease after treatment of chronic myeloid leukemia with allogeneic bone marrow transplantation. Blood 1996, 87:2588-2593.
    • (1996) Blood , vol.87 , pp. 2588-2593
    • Zhang, J.G.1    Lin, F.2    Chase, A.3
  • 52
    • 0037441629 scopus 로고    scopus 로고
    • Complete cytogenetic and molecular responses to interferon-alpha-based therapy for chronic myelogenous leukemia are associated with excellent long-term prognosis
    • Kantarjian HM, O'Brien S, Cortes J, et al.: Complete cytogenetic and molecular responses to interferon-alpha-based therapy for chronic myelogenous leukemia are associated with excellent long-term prognosis. Cancer 2003, 97:1033-1041.
    • (2003) Cancer , vol.97 , pp. 1033-1041
    • Kantarjian, H.M.1    O'Brien, S.2    Cortes, J.3
  • 53
    • 13344250478 scopus 로고    scopus 로고
    • Quantification of residual disease in chronic myelogenous leukemia patients on interferon-alpha therapy by competitive polymerase chain reaction
    • Hochhaus A, Lin F, Reiter A, et al.: Quantification of residual disease in chronic myelogenous leukemia patients on interferon-alpha therapy by competitive polymerase chain reaction. Blood 1996, 87:1549-1555.
    • (1996) Blood , vol.87 , pp. 1549-1555
    • Hochhaus, A.1    Lin, F.2    Reiter, A.3
  • 54
    • 0030861268 scopus 로고    scopus 로고
    • Monitoring the efficiency of interferon-alpha therapy in chronic myelogenous leukemia (CML) patients by competitive polymerase chain reaction
    • Hochhaus A, Lin F, Reiter A, et al.: Monitoring the efficiency of interferon-alpha therapy in chronic myelogenous leukemia (CML) patients by competitive polymerase chain reaction. Leukemia 1997, 11(Suppl 3):541-544.
    • (1997) Leukemia , vol.11 , Issue.SUPPL. 3 , pp. 541-544
    • Hochhaus, A.1    Lin, F.2    Reiter, A.3
  • 55
    • 0031950324 scopus 로고    scopus 로고
    • Conversion of interferon-induced, long-term cytogenetic remissions in chronic myelogenous leukemia to polymerase chain reaction negativity
    • Kurzrock R, Estrov Z, Kantarjian H, Talpaz M: Conversion of interferon-induced, long-term cytogenetic remissions in chronic myelogenous leukemia to polymerase chain reaction negativity. J Clin Oncol 1998, 16:1526-1531.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 1526-1531
    • Kurzrock, R.1    Estrov, Z.2    Kantarjian, H.3    Talpaz, M.4
  • 56
    • 0029133984 scopus 로고
    • Variable numbers of BCR-ABL transcripts persist in CML patients who achieve complete cytogenetic remission with interferon-alpha
    • Hochhaus A, Lin F, Reiter A, et al.: Variable numbers of BCR-ABL transcripts persist in CML patients who achieve complete cytogenetic remission with interferon-alpha. Br J Haematol 1995, 91:126-131.
    • (1995) Br. J. Haematol. , vol.91 , pp. 126-131
    • Hochhaus, A.1    Lin, F.2    Reiter, A.3
  • 57
    • 0037568145 scopus 로고    scopus 로고
    • Molecular responses to imatinib: (STI571) or interferon + Ara-C as initial therapy for CML: Results in the IRIS study
    • Hughes T, Kaeda J, Branford S, et al.: Molecular responses to imatinib: (STI571) or interferon + Ara-C as initial therapy for CML: results in the IRIS study. Blood 2002, 100:93a-94a.
    • (2002) Blood , vol.100
    • Hughes, T.1    Kaeda, J.2    Branford, S.3
  • 58
    • 0035992329 scopus 로고    scopus 로고
    • Imatinib mesylate for Philadelphia chromosome-positive, chronic-phase myeloid leukemia after failure of interferon-alpha: Follow-up results
    • Kantarjian HM, Talpaz M, O'Brien S, et al.: Imatinib mesylate for Philadelphia chromosome-positive, chronic-phase myeloid leukemia after failure of interferon-alpha: follow-up results. Clin Cancer Res 2002, 8:2177-2187.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 2177-2187
    • Kantarjian, H.M.1    Talpaz, M.2    O'Brien, S.3
  • 59
    • 0036738109 scopus 로고    scopus 로고
    • Early reduction of BCR-ABL mRNA transcript levels predicts cytogenetic response in chronic phase CML patients treated with imatinib after failure of interferon alpha
    • Merx K, Muller MC, Kreil S, et al.: Early reduction of BCR-ABL mRNA transcript levels predicts cytogenetic response in chronic phase CML patients treated with imatinib after failure of interferon alpha. Leukemia 2002, 16:1579-1583.
    • (2002) Leukemia , vol.16 , pp. 1579-1583
    • Merx, K.1    Muller, M.C.2    Kreil, S.3
  • 60
    • 0036891873 scopus 로고    scopus 로고
    • Quantitative monitoring of BCR/ABL transcript during STI-571 therapy
    • Wu CJ, Neuberg D, Chillemi A, et al.: Quantitative monitoring of BCR/ABL transcript during STI-571 therapy. Leuk Lymphoma 2002, 43:2281-2289.
    • (2002) Leuk. Lymphoma , vol.43 , pp. 2281-2289
    • Wu, C.J.1    Neuberg, D.2    Chillemi, A.3
  • 61
    • 0038092769 scopus 로고    scopus 로고
    • Emergence of clonal cytogenetic abnormalities in Ph- cells in some CML patients in cytogenetic remission to imatinib but restoration of polyclonal hematopoiesis in the majority
    • Bumm T, Muller C, Al-Ali HK, et al.: Emergence of clonal cytogenetic abnormalities in Ph- cells in some CML patients in cytogenetic remission to imatinib but restoration of polyclonal hematopoiesis in the majority. Blood 2003, 101:1941-1949.
    • (2003) Blood , vol.101 , pp. 1941-1949
    • Bumm, T.1    Muller, C.2    Al-Ali, H.K.3
  • 62
    • 0345382731 scopus 로고    scopus 로고
    • Demonstration of Philadelphia chromosome negative abnormal clones in patients with chronic myelogenous leukemia during major cytogenetic responses induced by imatinib mesylate
    • O'Dwyer ME, Gatter KM, Loriaux M, et al.: Demonstration of Philadelphia chromosome negative abnormal clones in patients with chronic myelogenous leukemia during major cytogenetic responses induced by imatinib mesylate. Leukemia 2003, 17:481-487.
    • (2003) Leukemia , vol.17 , pp. 481-487
    • O'Dwyer, M.E.1    Gatter, K.M.2    Loriaux, M.3
  • 63
    • 0024973417 scopus 로고
    • Avoiding false positives with PCR
    • Kwok S, Higuchi R: Avoiding false positives with PCR. Nature 1989, 339:237-238.
    • (1989) Nature , vol.339 , pp. 237-238
    • Kwok, S.1    Higuchi, R.2
  • 64
    • 9344257318 scopus 로고    scopus 로고
    • Persistence of multipotent progenitors expressing AML1/ETO transcripts in long-term remission patients with t(8;21) acute myelogenous leukemia
    • Miyamoto T, Nagafuji K, Akashi K, et al.: Persistence of multipotent progenitors expressing AML1/ETO transcripts in long-term remission patients with t(8;21) acute myelogenous leukemia. Blood 1996, 87:4789-4796.
    • (1996) Blood , vol.87 , pp. 4789-4796
    • Miyamoto, T.1    Nagafuji, K.2    Akashi, K.3
  • 65
    • 0028980278 scopus 로고
    • Persistence of RAR alpha-PML fusion mRNA detected by reverse transcriptase polymerase chain reaction in patients in long-term remission of acute promyelocytic leukaemia
    • Tobal K, Saunders MJ, Grey MR, Yin JA: Persistence of RAR alpha-PML fusion mRNA detected by reverse transcriptase polymerase chain reaction in patients in long-term remission of acute promyelocytic leukaemia. Br J Haematol 1995, 90:615-608.
    • (1995) Br. J. Haematol. , vol.90 , pp. 608-615
    • Tobal, K.1    Saunders, M.J.2    Grey, M.R.3    Yin, J.A.4
  • 66
    • 0032211172 scopus 로고    scopus 로고
    • The presence of typical and atypical BCR-ABL fusion genes in leukocytes of normal individuals: Biologic significance and implications for the assessement of minimal residual disease
    • Bose S, Deininger M, Gora-Tybor J, et al.: The presence of typical and atypical BCR-ABL fusion genes in leukocytes of normal individuals: biologic significance and implications for the assessement of minimal residual disease. Blood 1998, 92:3362-3367.
    • (1998) Blood , vol.92 , pp. 3362-3367
    • Bose, S.1    Deininger, M.2    Gora-Tybor, J.3
  • 67
    • 0034568023 scopus 로고    scopus 로고
    • The detection and significance of minimal residual disease in chronic myeloid leukemia
    • Radich JP: The detection and significance of minimal residual disease in chronic myeloid leukemia. Medicina (B Aires) 2000, 60:66-70.
    • (2000) Medicina (B Aires) , vol.60 , pp. 66-70
    • Radich, J.P.1
  • 68
    • 0032190250 scopus 로고    scopus 로고
    • Late relapsing childhood lymphoblastic leukemia
    • Vora A, Frost L, Goodeve A, et al.: Late relapsing childhood lymphoblastic leukemia. Blood 1998, 92:2334-2337.
    • (1998) Blood , vol.92 , pp. 2334-2337
    • Vora, A.1    Frost, L.2    Goodeve, A.3
  • 69
    • 0022229830 scopus 로고
    • Incidence of involvement of the B and T lymphocyte lineages in chronic myelogenous leukemia
    • Nitta M, Kato Y, Strife A, et al.: Incidence of involvement of the B and T lymphocyte lineages in chronic myelogenous leukemia. Blood 1985, 66:1053-1061.
    • (1985) Blood , vol.66 , pp. 1053-1061
    • Nitta, M.1    Kato, Y.2    Strife, A.3
  • 70
  • 71
    • 0030015814 scopus 로고    scopus 로고
    • Estimation of the number of mutations necessary to cause chronic myeloid leukaemia from epidemiological data
    • Vickers M: Estimation of the number of mutations necessary to cause chronic myeloid leukaemia from epidemiological data. Br J Haematol 1996, 94:1-4.
    • (1996) Br. J. Haematol. , vol.94 , pp. 1-4
    • Vickers, M.1
  • 72
    • 0028307601 scopus 로고
    • A comparison of the sensitivity of blood and bone marrow for the detection of minimal residual disease in chronic myeloid leukemia
    • Lin F, Goldman JM, Cross NC: A comparison of the sensitivity of blood and bone marrow for the detection of minimal residual disease in chronic myeloid leukemia. Br J Haematol 1994, 89:684-685.
    • (1994) Br. J. Haematol. , vol.89 , pp. 684-685
    • Lin, F.1    Goldman, J.M.2    Cross, N.C.3
  • 73
    • 0032190169 scopus 로고    scopus 로고
    • A special fluorescent in situ hybridization technique to study peripheral blood and assess the effectiveness of interferon therapy in chronic myeloid leukemia
    • Buno I, Wyatt WA, Zinsmeister AR, et al.: A special fluorescent in situ hybridization technique to study peripheral blood and assess the effectiveness of interferon therapy in chronic myeloid leukemia. Blood 1998, 92:2315-2321.
    • (1998) Blood , vol.92 , pp. 2315-2321
    • Buno, I.1    Wyatt, W.A.2    Zinsmeister, A.R.3
  • 74
    • 0034119298 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization on peripheral-blood specimens is a reliable method to evaluate cytogenetic response in chronic myeloid leukemia
    • Le Gouill S, Talmant F, Milpied N, et al.: Fluorescence in situ hybridization on peripheral-blood specimens is a reliable method to evaluate cytogenetic response in chronic myeloid leukemia. J Clin Oncol 2000, 18:1533-1538.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 1533-1538
    • Le Gouill, S.1    Talmant, F.2    Milpied, N.3
  • 75
    • 0345487506 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization (FISH) on peripheral blood smears for monitoring Philadelphia chromosome-positive chronic myeloid leukemia (CML) during interferon treatment: A new strategy for remission assessment
    • Muhlmann J, Thaler J, Hilbe W, et al.: Fluorescence in situ hybridization (FISH) on peripheral blood smears for monitoring Philadelphia chromosome-positive chronic myeloid leukemia (CML) during interferon treatment: a new strategy for remission assessment. Genes Chromosomes Cancer 1998, 21:90-100.
    • (1998) Genes Chromosomes Cancer , vol.21 , pp. 90-100
    • Muhlmann, J.1    Thaler, J.2    Hilbe, W.3
  • 76
    • 0030759998 scopus 로고    scopus 로고
    • Some observations on fluorescence in situ hybridization evaluation of chronic myelocytic leukemia
    • Chen Z, Notohamiprodjo M, Richards PD, et al.: Some observations on fluorescence in situ hybridization evaluation of chronic myelocytic leukemia. Cancer Genet Cytogenet 1997, 98:1-3.
    • (1997) Cancer Genet. Cytogenet. , vol.98 , pp. 1-3
    • Chen, Z.1    Notohamiprodjo, M.2    Richards, P.D.3
  • 77
    • 0036885719 scopus 로고    scopus 로고
    • Efficiency of interphase fluorescence in situ hybridization for BCR/ABL on peripheral blood smears for monitoring of CML patients: A comparison with bone marrow findings
    • Akel S, Kolialexi A, Mavrou A, et al.: Efficiency of interphase fluorescence in situ hybridization for BCR/ABL on peripheral blood smears for monitoring of CML patients: a comparison with bone marrow findings. Clin Lab Haematol 2002, 24:361-367.
    • (2002) Clin. Lab. Haematol. , vol.24 , pp. 361-367
    • Akel, S.1    Kolialexi, A.2    Mavrou, A.3


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