A stable neurotensin-based radiopharmaceutical for targeted imaging and therapy of neurotensin receptor-positive tumours

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 36, Issue 1, 2009, Pages 37-47

  García Garayoa, Elisa ^a   Bläuenstein, Peter ^a   Blanc, Alain ^a   Maes, Veronique ^b   Tourwé, Dirk ^b   Schubiger, P August ^a,c  

^a ETH Zurich   (Switzerland)

^b VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^c ETH ZURICH   (Switzerland)

Author keywords

188Re; 99mTc; Endocrinology; Neurotensin analogue; Oncology; Peptide receptor radionuclide therapy; Radiolabelled peptides; SPECT CT; Therapy (peptides); Tumour imaging

Indexed keywords

NEUROTENSIN DERIVATIVE; NEUROTENSIN RECEPTOR; NEUROTENSIN RECEPTOR 1; NEUROTENSIN VIII TC 99M; NEUROTENSIN X TC 99M; NEUROTENSIN XI TC 99M; NEUROTENSIN XII TC 99M; NEUROTENSIN XIX RE 188; NEUROTENSIN XIX TC 99M; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG METABOLISM; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; DRUG TUMOR LEVEL; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; ISOTOPE LABELING; MOUSE; NONHUMAN; NUDE MOUSE; RADIOACTIVITY; RECEPTOR AFFINITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TUMOR XENOGRAFT;

AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; HALF-LIFE; HUMANS; MICE; MOLECULAR WEIGHT; NEOPLASMS; NEUROTENSIN; ORGANOTECHNETIUM COMPOUNDS; RADIOISOTOPES; RADIOPHARMACEUTICALS; RECEPTORS, NEUROTENSIN; RHENIUM; STAINING AND LABELING; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED;

EID: 57249115097     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-008-0894-y     Document Type: Article

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