Modulation of group III metabotropic glutamate receptors by hydrogen ions

Pharmacology

Volumn 83, Issue 2, 2009, Pages 88-94

  Levinthal, Cynthia ^a,b   Barkdull, Lisa ^a   Jacobson, Pam ^a   Storjohann, Laura ^a   Van Wagenen, Bradford C ^a   Stormann, Thomas M ^a   Hammerland, Lance G ^a  

^a NPS Pharmaceutical Inc   (United States)

^b Q Therapeutics Inc   (United States)

Author keywords

Allosteric modulator; Hydrogen ions, pH sensitivity; mGluR4a, Group II mGluRs, Group I mGluRs

Indexed keywords

2 (CARBOXYCYCLOPROPYL)GLYCINE; 4 AMINOBUTYRIC ACID; ADENYLATE CYCLASE; CALCIUM; GLUTAMIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; METABOTROPIC RECEPTOR 1A; METABOTROPIC RECEPTOR 3; METABOTROPIC RECEPTOR 4; METABOTROPIC RECEPTOR 4A; METABOTROPIC RECEPTOR 5D; METABOTROPIC RECEPTOR 8B; PHOSPHOLIPASE C; PROTON; UNCLASSIFIED DRUG;

ACIDIFICATION; ALLOSTERISM; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FLUOROMETRY; HUMAN; HUMAN CELL; MAMMAL CELL; NEUROMODULATION; NEUROTRANSMITTER RELEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

ADENYLATE CYCLASE; ALLOSTERIC REGULATION; AMINO ACIDS, DICARBOXYLIC; ANIMALS; CALCIUM; CELL LINE; CELLS, CULTURED; EXTRACELLULAR FLUID; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; HUMANS; HYDROGEN-ION CONCENTRATION; INTRACELLULAR FLUID; NEUROTRANSMITTER AGENTS; PROTONS; RECEPTORS, METABOTROPIC GLUTAMATE; SIGNAL TRANSDUCTION; TYPE C PHOSPHOLIPASES; XENOPUS;

EID: 57149137562     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000180124     Document Type: Article

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