Histidine at position 1042 of the p150 region of a KRT live attenuated rubella vaccine strain is responsible for the temperature sensitivity

Vaccine

Volumn 27, Issue 2, 2009, Pages 234-242

  Sakata, Masafumi ^a   Komase, Katsuhiro ^b   Nakayama, Tetsuo ^a  

^a KITASATO UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

KRT vaccine strain; Reverse genetics; Rubella virus; Temperature sensitivity

Indexed keywords

COMPLEMENTARY DNA; HISTIDINE; LIVE VACCINE; METHYLTRANSFERASE; PROTEINASE; RUBELLA VACCINE; STRUCTURAL PROTEIN;

AMINO ACID COMPOSITION; ANIMAL CELL; ARTICLE; CHIMERA; CONTROLLED STUDY; GENE CONSTRUCT; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; RUBELLA VIRUS; STRAIN DIFFERENCE; TEMPERATURE SENSITIVITY; VIRUS REPLICATION; VIRUS STRAIN; VIRUS TITRATION; WILD TYPE;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; GENOME, VIRAL; HISTIDINE; METHYLTRANSFERASES; MOLECULAR SEQUENCE DATA; PEPTIDE HYDROLASES; POINT MUTATION; RABBITS; RUBELLA VACCINE; RUBELLA VIRUS; SEQUENCE ANALYSIS, DNA; TEMPERATURE; VACCINES, ATTENUATED; VERO CELLS; VIRAL PROTEINS;

EID: 57149104363     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2008.10.049     Document Type: Article

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